Published in Am J Hum Genet on August 30, 2006
Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One (2009) 3.00
Identifying susceptibility loci for nicotine dependence: 2008 update based on recent genome-wide linkage analyses. Hum Genet (2008) 1.94
Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples. Am J Hum Genet (2007) 1.73
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. Am J Med Genet B Neuropsychiatr Genet (2009) 1.68
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. Am J Med Genet B Neuropsychiatr Genet (2010) 1.48
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Drug Alcohol Depend (2007) 1.23
Genome-wide meta-analyses of smoking behaviors in African Americans. Transl Psychiatry (2012) 1.23
Genetics of nicotine dependence and pharmacotherapy. Biochem Pharmacol (2007) 1.21
Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence. Hum Genet (2011) 1.19
Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res (2008) 1.14
Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence. Biol Psychiatry (2008) 1.13
Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. Mol Psychiatry (2009) 1.09
Meta-analysis of 15 genome-wide linkage scans of smoking behavior. Biol Psychiatry (2010) 1.08
Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. Biol Psychiatry (2008) 1.03
Substance dependence low-density whole genome association study in two distinct American populations. Hum Genet (2008) 1.03
Cannabinoid receptor 1 gene association with nicotine dependence. Arch Gen Psychiatry (2008) 1.01
Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations. PLoS One (2009) 1.00
Constitutional mechanisms of vulnerability and resilience to nicotine dependence. Mol Psychiatry (2009) 0.96
Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence. Neuropsychopharmacology (2009) 0.94
Evaluation of the brief wisconsin inventory of smoking dependence motives in african-american and European-american heavy smokers. Front Psychiatry (2012) 0.92
Genetic linkage findings for DSM-IV nicotine withdrawal in two populations. Am J Med Genet B Neuropsychiatr Genet (2009) 0.92
Determination of Methylated CpG Sites in the Promoter Region of Catechol-O-Methyltransferase (COMT) and their Involvement in the Etiology of Tobacco Smoking. Front Psychiatry (2010) 0.87
Neuroimaging, genetics and the treatment of nicotine addiction. Behav Brain Res (2008) 0.87
Genetics of GABAergic signaling in nicotine and alcohol dependence. Hum Genet (2011) 0.87
Genome-wide scan for self-rating of the effects of alcohol in American Indians. Psychiatr Genet (2010) 0.85
A faster pedigree-based generalized multifactor dimensionality reduction method for detecting gene-gene interactions. Stat Interface (2011) 0.84
The contribution of rare and common variants in 30 genes to risk nicotine dependence. Mol Psychiatry (2014) 0.82
Advances in genetic studies of substance abuse in China. Shanghai Arch Psychiatry (2013) 0.81
Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants. Mol Neurobiol (2013) 0.79
Organic cation transporter variation and response to smoking cessation therapies. Nicotine Tob Res (2014) 0.78
Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11. Am J Med Genet B Neuropsychiatr Genet (2009) 0.77
Identification of CHRNA5 rare variants in African-American heavy smokers. Psychiatr Genet (2014) 0.77
Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions. Mol Psychiatry (2016) 0.75
Detecting Gene-Gene Interactions Associated with Multiple Complex Traits with U-Statistics. Curr Genomics (2016) 0.75
The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict (1991) 63.91
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet (1995) 49.77
PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25
Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet (1997) 7.78
Cigarette smoking among adults--United States, 2000. MMWR Morb Mortal Wkly Rep (2002) 7.32
Nicotine metabolism and intake in black and white smokers. JAMA (1998) 5.03
A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
A population-based twin study in women of smoking initiation and nicotine dependence. Psychol Med (1999) 3.78
Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered (2003) 3.33
The genetic epidemiology of smoking. Nicotine Tob Res (1999) 3.21
Common genetic vulnerability for nicotine and alcohol dependence in men. Arch Gen Psychiatry (1999) 3.04
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet (2005) 3.03
Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet (2005) 2.18
Tobacco, alcohol and drug use in eight- to sixteen-year-old twins: the Virginia Twin Study of Adolescent Behavioral Development. J Stud Alcohol (1999) 1.97
All LODs are not created equal. Am J Hum Genet (2000) 1.94
A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet A (2004) 1.88
Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Mol Psychiatry (1999) 1.79
Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. Am J Med Genet B Neuropsychiatr Genet (2004) 1.67
Significant association of BDNF haplotypes in European-American male smokers but not in European-American female or African-American smokers. Am J Med Genet B Neuropsychiatr Genet (2005) 1.55
A genome-wide search for loci contributing to smoking and alcoholism. Genet Epidemiol (1999) 1.55
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q. Genet Epidemiol (1999) 1.28
Progress in searching for susceptibility loci and genes for smoking-related behaviour. Clin Genet (2004) 1.24
Linkage analysis of smoking initiation and quantity in Dutch sibling pairs. Pharmacogenomics J (2004) 1.20
Smoking and alcohol consumption in adult male twins: genetic heritability and shared environmental influences. J Subst Abuse (1990) 1.15
The consumption of tobacco, alcohol, and coffee in Caucasian male twins: a multivariate genetic analysis. J Subst Abuse (1996) 1.14
Multiple genome-wide analyses of smoking behavior in the Framingham Heart Study. BMC Genet (2003) 1.14
Racial and ethnic differences in predictors of smoking cessation. Subst Use Misuse (2006) 1.11
Mapping and verification of susceptibility loci for smoking quantity using permutation linkage analysis. Pharmacogenomics J (2005) 1.11
Genomic screen for loci associated with tobacco usage in Mission Indians. BMC Med Genet (2006) 1.06
Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans. Biol Psychiatry (2006) 1.05
A possible smoking susceptibility locus on chromosome 11p12: evidence from sex-limitation linkage analyses in a sample of Australian twin families. Behav Genet (2005) 1.00
Genetic analysis of maximum cigarette-use phenotypes. BMC Genet (2003) 0.93
Genome-wide linkage scan to identify Loci for age at first cigarette in Dutch sibling pairs. Behav Genet (2005) 0.92
Proteins differentially expressed in response to nicotine in five rat brain regions: identification using a 2-DE/MS-based proteomics approach. Proteomics (2006) 0.92
Dynamin-2 associates with the dopamine receptor signalplex and regulates internalization of activated D2 receptors. Cell Signal (2004) 0.87
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med (2006) 10.97
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science (2007) 6.77
Optimal two-stage genotyping in population-based association studies. Genet Epidemiol (2003) 6.01
Oral topiramate for treatment of alcohol dependence: a randomised controlled trial. Lancet (2003) 4.79
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature (2012) 4.00
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell (2003) 3.86
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol (2007) 3.63
Improved power by use of a weighted score test for linkage disequilibrium mapping. Am J Hum Genet (2006) 3.36
Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered (2003) 3.33
Choosing an optimal method to combine P-values. Stat Med (2009) 3.15
The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol (2007) 3.01
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet (2003) 2.92
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet (2005) 2.80
Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study. Ann Intern Med (2013) 2.74
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat Immunol (2003) 2.48
Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet (2004) 2.36
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol (2003) 2.26
Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet (2004) 2.21
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Mol Cell (2006) 2.21
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. Am J Hum Genet (2008) 2.20
Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet (2005) 2.18
A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Stat Med (2006) 2.18
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (2006) 2.08
Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am J Respir Crit Care Med (2004) 2.03
Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetes. Circulation (2002) 1.91
Continuity of outpatient and inpatient care by primary care physicians for hospitalized older adults. JAMA (2009) 1.90
Outcomes associated with microalbuminuria: effect modification by chronic kidney disease. J Am Coll Cardiol (2013) 1.89
Preoperative statin administration is associated with lower mortality and decreased need for postoperative hemodialysis in patients undergoing coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth (2009) 1.88
The associations between race and geographic area and quality-of-care indicators in patients approaching ESRD. Clin J Am Soc Nephrol (2013) 1.87
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. J Diabetes Complications (2005) 1.87
Hyponatremia, hypernatremia, and mortality in patients with chronic kidney disease with and without congestive heart failure. Circulation (2012) 1.86
Self-reported race and genetic admixture. N Engl J Med (2006) 1.85
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A (2003) 1.84
The meaning of interaction. Hum Hered (2010) 1.83
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models. Mol Cancer Ther (2011) 1.81
A whole-genome scan for obstructive sleep apnea and obesity. Am J Hum Genet (2002) 1.81
Influence of comorbid conditions on long-term mortality after pneumonia in older people. J Am Geriatr Soc (2007) 1.79
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79
Trends in end-of-life ICU use among older adults with advanced lung cancer. Chest (2007) 1.76
External validation of medicare claims for breast cancer chemotherapy compared with medical chart reviews. Med Care (2006) 1.74
Effectiveness of adjuvant chemotherapy for node-positive operable breast cancer in older women. J Gerontol A Biol Sci Med Sci (2005) 1.73
Continuity of care and intensive care unit use at the end of life. Arch Intern Med (2009) 1.70
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest (2008) 1.66
The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1. Blood (2009) 1.65
Long-term survival of dialysis patients in the United States with prosthetic heart valves: should ACC/AHA practice guidelines on valve selection be modified? Circulation (2002) 1.63
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes (2007) 1.61
A survey of oral and maxillofacial surgeons' tobacco-use-related knowledge, attitudes and intervention behaviors. J Am Dent Assoc (2008) 1.58
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia. Pediatr Crit Care Med (2008) 1.57
Significant association of BDNF haplotypes in European-American male smokers but not in European-American female or African-American smokers. Am J Med Genet B Neuropsychiatr Genet (2005) 1.55
Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet (2007) 1.55
Trial design: The St. Jude Children's Research Hospital Cancer Survivors Tobacco Quit Line study. Contemp Clin Trials (2009) 1.55
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet (2003) 1.53
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. Am J Med Genet B Neuropsychiatr Genet (2010) 1.48
Poleward tubulin flux in spindles: regulation and function in mitotic cells. Mol Biol Cell (2007) 1.47
Differentiation of normal thymus from anterior mediastinal lymphoma and lymphoma recurrence at pediatric PET/CT. Radiology (2011) 1.46
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (2007) 1.44
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol (2002) 1.44
Sampling correction in linkage analysis. Genet Epidemiol (2004) 1.43
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol (2011) 1.43
Color doppler hemodynamic study of the superficial temporal arteries in superficial temporal artery-middle cerebral artery (STA-MCA) bypass surgery for Moyamoya disease. World Neurosurg (2011) 1.43
Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One (2008) 1.41
Pancreatic cancer in the general population: Improvements in survival over the last decade. J Gastrointest Surg (2006) 1.41
Plasma aldosterone is independently associated with the metabolic syndrome. Hypertension (2006) 1.40
The 5A's vs 3A's plus proactive quitline referral in private practice dental offices: preliminary results. Tob Control (2007) 1.40
Survival advantage in Medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual? Catheter Cardiovasc Interv (2008) 1.39
Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association. Hum Hered (2007) 1.39