Human brain evolution.

Variation in transcription factor binding among humans. Science (2010) 9.33

Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates. Proc Natl Acad Sci U S A (2010) 1.47

Intra- and interspecific variation in primate gene expression patterns. Science (2002) 7.92

The evolution of gene expression levels in mammalian organs. Nature (2011) 7.16

A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature (2005) 5.51

Fast mapping of short sequences with mismatches, insertions and deletions using index structures. PLoS Comput Biol (2009) 4.24

Estimating accuracy of RNA-Seq and microarrays with proteomics. BMC Genomics (2009) 3.87

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. Genome Res (2010) 2.44

FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics (2007) 2.32

Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab (2011) 2.22

Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol (2005) 1.82

Transcriptional neoteny in the human brain. Proc Natl Acad Sci U S A (2009) 1.78

Aging and gene expression in the primate brain. PLoS Biol (2005) 1.76

Sequence features associated with microRNA strand selection in humans and flies. BMC Genomics (2009) 1.76

Birth and expression evolution of mammalian microRNA genes. Genome Res (2012) 1.64

Comprehensive survey of human brain microRNA by deep sequencing. BMC Genomics (2010) 1.59

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. PLoS Biol (2011) 1.57

Widespread expression of piRNA-like molecules in somatic tissues. Nucleic Acids Res (2011) 1.56

Evidence for human microRNA-offset RNAs in small RNA sequencing data. Bioinformatics (2009) 1.55

Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron (2008) 1.54

Comparison of protein and mRNA expression evolution in humans and chimpanzees. PLoS One (2007) 1.42

MicroRNA expression and regulation in human, chimpanzee, and macaque brains. PLoS Genet (2011) 1.40

Human and chimpanzee gene expression differences replicated in mice fed different diets. PLoS One (2008) 1.35

Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq. PLoS Comput Biol (2010) 1.33

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques. Genome Res (2012) 1.27

Widespread splicing changes in human brain development and aging. Mol Syst Biol (2013) 1.23

Gene expression becomes heterogeneous with age. Curr Biol (2006) 1.18

Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci (2013) 1.16

Positive selection on gene expression in the human brain. Curr Biol (2006) 1.14

Rapid metabolic evolution in human prefrontal cortex. Proc Natl Acad Sci U S A (2011) 1.09

Evolution of the human-specific microRNA miR-941. Nat Commun (2012) 1.06

Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel. Physiol Genomics (2010) 0.98

Systematic analysis of gene expression in human brains before and after death. Genome Biol (2005) 0.98

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development. Am J Hum Genet (2008) 0.93

Ab initio identification of transcription start sites in the Rhesus macaque genome by histone modification and RNA-Seq. Nucleic Acids Res (2010) 0.90

Functional analysis of human and chimpanzee promoters. Genome Biol (2005) 0.89

Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. Genome Biol (2015) 0.89

Stress-associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain. Aging Cell (2012) 0.87

The effects of probe binding affinity differences on gene expression measurements and how to deal with them. Bioinformatics (2009) 0.86

Evolution of neuronal and endothelial transcriptomes in primates. Genome Biol Evol (2010) 0.85

Evolutionary and ontogenetic changes in RNA editing in human, chimpanzee, and macaque brains. RNA (2013) 0.83

Spatial proximity and similarity of the epigenetic state of genome domains. PLoS One (2012) 0.82

Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series. BMC Bioinformatics (2011) 0.82

Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes. BMC Genomics (2014) 0.81

Accelerated aging-related transcriptome changes in the female prefrontal cortex. Aging Cell (2012) 0.76

Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content. PLoS One (2012) 0.75