Published in Cell on January 25, 1991
Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol (1992) 12.96
Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med (2010) 7.31
Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol (1998) 4.43
Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am J Pathol (1998) 4.41
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci U S A (1991) 3.95
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc Natl Acad Sci U S A (1996) 3.88
Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth. Mol Cell Biol (1997) 3.76
Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest (1995) 3.69
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol (2001) 3.32
Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev (1999) 3.32
The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. Mol Cell Biol (1993) 2.95
Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J Cell Biol (2001) 2.95
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways. Proc Natl Acad Sci U S A (1997) 2.88
Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc Natl Acad Sci U S A (1991) 2.53
Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. Proc Natl Acad Sci U S A (1998) 2.48
Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J Cell Biol (1995) 2.45
B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. Blood (2008) 2.41
PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis. J Clin Invest (2002) 2.31
Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer. J Clin Invest (1993) 2.29
Secreted cathepsin L generates endostatin from collagen XVIII. EMBO J (2000) 2.24
Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1. Proc Natl Acad Sci U S A (1996) 2.12
Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior. Am J Pathol (1997) 2.10
Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc Natl Acad Sci U S A (1993) 2.09
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci U S A (1996) 2.02
Tumor angiogenesis in advanced stage ovarian carcinoma. Am J Pathol (1995) 2.02
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am J Pathol (2002) 1.96
Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester. Biochem J (1993) 1.83
Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells. Proc Natl Acad Sci U S A (1995) 1.80
The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am J Pathol (1994) 1.79
Role of p38 MAP Kinase Signal Transduction in Solid Tumors. Genes Cancer (2013) 1.73
Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis. J Clin Invest (1993) 1.73
Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer. Am J Pathol (1993) 1.71
A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1. Mol Cell Biol (1998) 1.70
Expression of Fas ligand in liver metastases of human colonic adenocarcinomas. Proc Natl Acad Sci U S A (1997) 1.68
A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation. EMBO J (2000) 1.67
Technical considerations for studying cancer metastasis in vivo. Clin Exp Metastasis (1997) 1.62
Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice. Mol Cell Biol (1992) 1.62
Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J (1994) 1.61
The clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer. Clin Cancer Res (2006) 1.59
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter. Mol Cell Biol (1997) 1.57
Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase. Hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle. J Clin Invest (1996) 1.56
Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo. J Clin Invest (1997) 1.53
Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (2001) 1.52
Urokinase type plasminogen activator receptor expression in colorectal neoplasms. Gut (1998) 1.50
Cooperative effect of TNFalpha, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity. J Cell Biol (1996) 1.49
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Mol Cell Biol (1995) 1.47
Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus. J Clin Invest (2002) 1.47
The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors. Am J Pathol (2003) 1.47
Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer. World J Surg (2010) 1.45
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc Natl Acad Sci U S A (1993) 1.45
An emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancers. Neuroscientist (2008) 1.43
Matrix metalloproteinase inhibitors. Invest New Drugs (1997) 1.43
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy. J Cell Biol (2005) 1.42
Concentration of vascular endothelial growth factor in the tumour tissue as a prognostic factor of soft tissue sarcomas. Br J Cancer (2001) 1.41
Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest New Drugs (2004) 1.40
Breakdown of the endothelial barrier function in tumor cell transmigration. Biophys J (2007) 1.39
Cancer as robust intrinsic state of endogenous molecular-cellular network shaped by evolution. Med Hypotheses (2007) 1.39
Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am J Pathol (1993) 1.39
Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer. Mol Cancer (2003) 1.39
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225). EMBO J (1992) 1.38
Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53. Nucleic Acids Res (1995) 1.37
Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene. Proc Natl Acad Sci U S A (1997) 1.36
Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis. Proc Natl Acad Sci U S A (1999) 1.35
Gelatinase A activity directly modulates melanoma cell adhesion and spreading. EMBO J (1995) 1.34
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. Curr Oncol (2006) 1.34
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2. J Virol (1999) 1.33
c-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans. Am J Pathol (1992) 1.33
Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis. Proc Natl Acad Sci U S A (1995) 1.33
The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells. J Cell Biol (1998) 1.32
FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma. Br J Cancer (2003) 1.32
The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. J Clin Invest (1996) 1.31
Host microvasculature influence on tumor vascular morphology and endothelial gene expression. Am J Pathol (1998) 1.31
Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential. Clin Exp Metastasis (1998) 1.28
The role of the tissue microenvironment in the regulation of cancer cell motility and invasion. Cell Commun Signal (2010) 1.27
An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin. J Cell Biol (1994) 1.25
Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well. Proc Natl Acad Sci U S A (1996) 1.25
Quantitation of TIMP-1 in plasma of healthy blood donors and patients with advanced cancer. Br J Cancer (1999) 1.24
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth. Int J Cancer (2007) 1.23
Structural organization and chromosomal localization of the mouse collagenase type I gene. Biochem J (1995) 1.22
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin. Mol Cancer Ther (2009) 1.20
Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells. Appl Phys Lett (2010) 1.19
Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors. Invest New Drugs (2007) 1.18
Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro. J Cell Biol (1992) 1.18
Relationship between phenotypes of cell-function differentiation and pathobiological behavior of gastric carcinomas. World J Gastroenterol (2001) 1.17
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues. Am J Pathol (2001) 1.17
A Trypanosoma cruzi-secreted 80 kDa proteinase with specificity for human collagen types I and IV. Biochem J (1997) 1.17
In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer. Clin Exp Metastasis (1997) 1.16
Tear film MMP accumulation and corneal disease. Br J Ophthalmol (2001) 1.16
Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E. Br J Cancer (1998) 1.16
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites. Biochemistry (2007) 1.16
Inhibition of prostate cancer cell colony formation by the flavonoid quercetin correlates with modulation of specific regulatory genes. Clin Diagn Lab Immunol (2004) 1.14
KAI1 metastasis suppressor gene is frequently down-regulated in cervical carcinoma. Am J Pathol (2001) 1.14
TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression. Clin Exp Metastasis (2008) 1.14
Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach. Am J Pathol (2000) 1.13
Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils. Biochem J (1997) 1.13
AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins. Mol Cell Biol (2006) 1.12
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell (1996) 6.52
Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity. J Exp Med (1982) 5.33
Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science (1997) 4.83
Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature (1989) 3.75
Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res (1991) 3.47
Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem (1994) 3.37
Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell (1991) 3.21
Matrix metalloproteinases and metastasis. Cancer Chemother Pharmacol (1999) 2.91
Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions. Nat Med (1995) 2.74
Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res (1990) 2.40
Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential. Cancer Res (1989) 2.39
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Cell (1990) 2.36
Identification of a second human nm23 gene, nm23-H2. Cancer Res (1991) 2.31
Molecular aspects of tumor cell invasion and metastasis. Cancer (1993) 2.24
Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res (1994) 2.20
Regulation of murine macrophage Ia-antigen expression by products of activated spleen cells. J Exp Med (1980) 2.19
Role of the alpha v beta 3 integrin in human melanoma cell invasion. Proc Natl Acad Sci U S A (1992) 2.18
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. Am J Pathol (1992) 2.17
A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest. J Natl Cancer Inst (1994) 2.16
Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst (1991) 2.15
Metalloproteinases and cancer invasion. Semin Cancer Biol (1990) 2.07
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. Oncogene (1993) 2.04
Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro. J Cell Physiol (1993) 2.01
Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphokines and recombinant interferons. J Clin Invest (1984) 2.00
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma. Cancer Res (2001) 1.99
In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1. J Clin Invest (1998) 1.95
Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J Cell Physiol (1993) 1.88
Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. Am J Pathol (1990) 1.82
Regulation of murine macrophage Ia antigen expression by an immune interferon-like lymphokine: inhibitory effect of endotoxin. J Immunol (1982) 1.79
Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance. J Biol Chem (1999) 1.78
Validation of a model of colon cancer progression. J Pathol (2000) 1.76
A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential. J Biol Chem (1993) 1.69
The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur Respir J (1994) 1.68
Structural biochemistry and activation of matrix metalloproteases. Curr Opin Cell Biol (1993) 1.65
Matrix metalloproteinases in renal development and disease. J Am Soc Nephrol (2000) 1.64
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9. Biochemistry (1994) 1.63
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells. Mol Cell Biol (1999) 1.62
TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int J Cancer (1998) 1.58
Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer (1994) 1.57
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM). Hum Pathol (1997) 1.53
Nm23/nucleoside diphosphate kinase: toward a structural and biochemical understanding of its biological functions. Bioessays (1995) 1.52
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma. Cancer Res (1991) 1.52
Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes. J Biol Chem (1992) 1.46
Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan. J Neurosci (1998) 1.41
Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia. Cancer Res (1993) 1.41
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions. J Biol Chem (1992) 1.40
Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis. Am J Pathol (1996) 1.40
Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan's syndrome. Circulation (1998) 1.40
Induction of nm23 gene expression in human colonic neoplasms and equal expression in colon tumors of high and low metastatic potential. J Natl Cancer Inst (1991) 1.40
Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window. Brain Res (1995) 1.40
Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition. J Biol Chem (2000) 1.39
Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression. Mod Pathol (1991) 1.39
Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions. Am J Pathol (1996) 1.38
Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas. Oncogene (1993) 1.38
Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis. Breast Cancer Res (2000) 1.38
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. Am J Pathol (1994) 1.36
Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine-dependent protein phosphotransferase pathways in vitro. J Biol Chem (1997) 1.36
Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase. J Biol Chem (1996) 1.36
Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1. J Clin Invest (1993) 1.36
Inhibition of cell motility after nm23 transfection of human and murine tumor cells. Cancer Res (1993) 1.35
Gelatinase A activity directly modulates melanoma cell adhesion and spreading. EMBO J (1995) 1.34
Nm23/nucleoside diphosphate kinase in human cancers. J Bioenerg Biomembr (2000) 1.29
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells. J Biol Chem (1996) 1.28
92-kd type IV collagenase (matrix metalloproteinase-9) activity in human amniochorion increases with labor. Am J Pathol (1995) 1.26
Quantitative reverse zymography: analysis of picogram amounts of metalloproteinase inhibitors using gelatinase A and B reverse zymograms. Anal Biochem (1997) 1.26
New approaches to proteomic analysis of breast cancer. Proteomics (2001) 1.23
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis. Clin Exp Metastasis (1998) 1.22
TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase. Brain Res (1992) 1.21
Angiogenesis and colonization in the tumor metastatic process: basic and applied advances. FASEB J (1994) 1.20
Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production. J Biol Chem (1994) 1.19
MMP-2: expression, activation and inhibition. Enzyme Protein (1996) 1.19
Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane. Mod Pathol (1994) 1.19
Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells. J Natl Cancer Inst (2001) 1.18
Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase. Cancer Res (1992) 1.18
Primate smooth muscle cell migration from aortic explants is mediated by endogenous platelet-derived growth factor and basic fibroblast growth factor acting through matrix metalloproteinases 2 and 9. Circulation (1997) 1.17
Production of immune interferon by an interleukin 2-independent murine T cell line. Proc Natl Acad Sci U S A (1982) 1.16
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors. Cancer Res (1993) 1.16
Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J Biol Chem (1995) 1.16
Tissue inhibitor of metalloproteinase-1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis. Am J Pathol (2001) 1.14
Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies. Int J Cancer (1994) 1.14
Bovine dentin phosphophoryn: composition and molecular weight. Biochemistry (1983) 1.13
Matrix metalloproteinases. Novel targets for directed cancer therapy. Drugs Aging (1997) 1.13
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in reactive and neoplastic lymphoid cells. Blood (1997) 1.12
Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy. Cancer Res (1992) 1.11
Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity. Proc Natl Acad Sci U S A (1997) 1.10
Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas. Clin Exp Metastasis (1996) 1.09
Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens. Am J Pathol (1991) 1.09
Embryonic expression of nm23 during mouse organogenesis. Cell Growth Differ (1992) 1.08
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo. Clin Exp Metastasis (1996) 1.08
An added dimension: will three-dimensional cultures improve our understanding of drug resistance? J Natl Cancer Inst (1994) 1.07
Cancer prognostics: past, present and p27. Nat Med (1997) 1.06
Type I collagen shows a specific binding affinity for bovine dentin phosphophoryn. Calcif Tissue Int (1986) 1.06
Cancer invasion and metastasis: positive and negative regulatory elements. Cancer Invest (1991) 1.06
Bovine dentin phosphophoryn: calcium ion binding properties of a high molecular weight preparation. Calcif Tissue Int (1987) 1.06
The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion. Cancer Res (1993) 1.06
Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo. Clin Exp Metastasis (1995) 1.05