Published in Life Sci on October 14, 2006
Glycoprofiling of cancer biomarkers: Label-free electrochemical lectin-based biosensors. Open Chem (2015) 0.79
TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol (2012) 4.19
Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med (2015) 3.09
FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Cell Mol Immunol (2005) 1.74
Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol Immunol (2006) 1.35
Human coronavirus 229E binds to CD13 in rafts and enters the cell through caveolae. J Virol (2004) 1.18
Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms. Cancer Sci (2011) 1.17
Phase I, dose escalation and pharmacokinetic study of cediranib (RECENTIN), a highly potent and selective VEGFR signaling inhibitor, in Japanese patients with advanced solid tumors. Cancer Chemother Pharmacol (2009) 1.13
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing. Brain Tumor Pathol (2011) 1.12
Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis. Am J Physiol Endocrinol Metab (2007) 1.11
Phase I and pharmacokinetic study of dacomitinib (PF-00299804), an oral irreversible, small molecule inhibitor of human epidermal growth factor receptor-1, -2, and -4 tyrosine kinases, in Japanese patients with advanced solid tumors. Invest New Drugs (2012) 1.11
Randomized phase III trial of regorafenib in metastatic colorectal cancer: analysis of the CORRECT Japanese and non-Japanese subpopulations. Invest New Drugs (2014) 1.03
Carcinoma of duodenum arising from Brunner's gland. J Gastroenterol (2002) 1.00
Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit. BMC Cancer (2013) 0.99
Forensic hair analysis to identify animal species on a case of pet animal abuse. Int J Legal Med (2009) 0.99
A case of V-A shunt catheters migration into the pulmonary artery. Leg Med (Tokyo) (2008) 0.98
Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation. Biochem Biophys Res Commun (2011) 0.97
Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis. Int Immunopharmacol (2010) 0.96
S-1 monotherapy as second-line treatment for advanced pancreatic cancer after gemcitabine failure. Jpn J Clin Oncol (2010) 0.96
Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P. Cell Mol Immunol (2006) 0.96
Clinical outcome of Japanese metastatic colorectal cancer patients harbouring the KRAS p.G13D mutation treated with cetuximab + irinotecan. Jpn J Clin Oncol (2012) 0.95
Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin. Gastric Cancer (2010) 0.95
Postmortem pulmonary edema: a comparison between immediate and delayed postmortem computed tomography. Leg Med (Tokyo) (2011) 0.94
KRAS mutational status in Japanese patients with colorectal cancer: results from a nationwide, multicenter, cross-sectional study. Jpn J Clin Oncol (2013) 0.94
Sudden death as a late sequel of Kawasaki disease: postmortem CT demonstration of coronary artery aneurysm. Forensic Sci Int (2012) 0.93
Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow. Int Immunol (2010) 0.93
Cardiovascular gas on non-traumatic postmortem computed tomography (PMCT): the influence of cardiopulmonary resuscitation. Radiat Med (2005) 0.92
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity. J Nutr (2005) 0.92
Three cases of sudden death due to butane or propane gas inhalation: analysis of tissues for gas components. Forensic Sci Int (2004) 0.92
Efficacy of sequential methotrexate and 5-fluorouracil (MTX/5FU) in improving oral intake in patients with advanced gastric cancer with severe peritoneal dissemination. Gastric Cancer (2009) 0.91
Risk factors and clinical courses of chemoradiation-related arterio-esophageal fistula in esophageal cancer patients with clinical invasion of the aorta. Int J Clin Oncol (2011) 0.91
Effects of long-term administrations of aconitine on electrocardiogram and tissue concentrations of aconitine and its metabolites in mice. Forensic Sci Int (2005) 0.91
Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta. Acta Crystallogr D Biol Crystallogr (2004) 0.91
Leptomeningeal carcinomatosis associated with gastric cancer. Int J Clin Oncol (2011) 0.91
Characteristic signal intensity changes on postmortem magnetic resonance imaging of the brain. Jpn J Radiol (2010) 0.91
Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate. Bioorg Med Chem (2005) 0.90
Efficacy and safety of an irinotecan plus bolus 5-fluorouracil and L-leucovorin regimen for metastatic colorectal cancer in Japanese patients: experience in a single institution in Japan. Jpn J Clin Oncol (2007) 0.90
Potential effect on cellular response to cadmium of a single-nucleotide A --> G polymorphism in the promoter of the human gene for metallothionein IIA. Hum Genet (2006) 0.89
Non-traumatic postmortem computed tomographic (PMCT) findings of the lung. Forensic Sci Int (2004) 0.89
Weekly Paclitaxel after failure of gemcitabine in pancreatic cancer patients with malignant ascites: a retrospective study. Jpn J Clin Oncol (2010) 0.89
Postmortem computed tomographic (PMCT) demonstration of the relation between gastrointestinal (GI) distension and hepatic portal venous gas (HPVG). Radiat Med (2004) 0.89
Postmortem computed tomography for detecting causes of sudden death in infants and children: retrospective review of cases. Radiat Med (2006) 0.89
Subcellular location of the soluble lytic transglycosylase homologue in Staphylococcus aureus. Curr Microbiol (2004) 0.88
Postmortem magnetic resonance imaging dealing with low temperature objects. Magn Reson Med Sci (2010) 0.87
Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study. Jpn J Clin Oncol (2012) 0.86
Phase I study of sunitinib plus modified FOLFOX6 in Japanese patients with treatment-naive colorectal cancer. Anticancer Res (2012) 0.86
Impact of baseline sum of longest diameter in target lesions by RECIST on survival of patients with metastatic colorectal cancer. Jpn J Clin Oncol (2008) 0.86
A phase I study of intravenous aflibercept with FOLFIRI in Japanese patients with previously treated metastatic colorectal cancer. Invest New Drugs (2012) 0.86
Effects of central administration of glucagon on feed intake and endocrine responses in sheep. Anim Sci J (2009) 0.85
Ectodomain shedding of SHPS-1 and its role in regulation of cell migration. J Biol Chem (2004) 0.85
Rapid detection of semenogelin by one-step immunochromatographic assay for semen identification. J Immunol Methods (2004) 0.85
Dual contradictory roles of cAMP signaling pathways in hydroxyl radical production in the rat striatum. Free Radic Biol Med (2012) 0.85
A large form of secretogranin III functions as a sorting receptor for chromogranin A aggregates in PC12 cells. Mol Endocrinol (2008) 0.85
Removal of sphingosine 1-phosphate receptor-3 (S1P(3)) agonism is essential, but inadequate to obtain immunomodulating 2-aminopropane-1,3-diol S1P(1) agonists with reduced effect on heart rate. J Med Chem (2010) 0.85
cAMP production mediated through P2Y(11)-like receptors in rat striatum due to severe, but not moderate, carbon monoxide poisoning. Toxicology (2011) 0.85
Intravenous administration of amino acids during anesthesia stimulates muscle protein synthesis and heat accumulation in the body. Am J Physiol Endocrinol Metab (2005) 0.84
Modified FOLFOX-6 therapy for heavily pretreated advanced gastric cancer refractory to fluorouracil, irinotecan, cisplatin and taxanes: a retrospective study. Jpn J Clin Oncol (2012) 0.84
Comparison of safety and efficacy of S-1 monotherapy and S-1 plus cisplatin therapy in elderly patients with advanced gastric cancer. Int J Clin Oncol (2011) 0.84
An accidental case of aconite poisoning due to Kampo herbal medicine ingestion. Leg Med (Tokyo) (2009) 0.84
Activity of S-1 in advanced or recurrent gastric cancer patients after failure of prior chemotherapy, including irinotecan + cisplatin or fluorouracil (except S-1). Jpn J Clin Oncol (2009) 0.84
Central administration of somatostatin stimulates feeding behavior in chicks. Gen Comp Endocrinol (2009) 0.84
Existence of a threshold for hydroxyl radical generation independent of hypoxia in rat striatum during carbon monoxide poisoning. Arch Toxicol (2011) 0.84
Dilatation of the heart on postmortem computed tomography (PMCT): comparison with live CT. Radiat Med (2003) 0.84
Risk factors of familial pancreatic cancer in Japan: current smoking and recent onset of diabetes. Pancreas (2011) 0.83
A column-switching LC/MS/ESI method for detecting tetrodotoxin and Aconitum alkaloids in serum. Leg Med (Tokyo) (2003) 0.83
Central administration of insulin suppresses food intake in chicks. Neurosci Lett (2007) 0.83
Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate. J Nutr Sci Vitaminol (Tokyo) (2004) 0.83
Cerebral relaxation times from postmortem MR imaging of adults. Magn Reson Med Sci (2014) 0.83
Irinotecan plus cisplatin therapy and S-1 plus cisplatin therapy for advanced or recurrent gastric cancer in a single institution. Jpn J Clin Oncol (2008) 0.83
ABO genotyping by TaqMan assay and allele frequencies in a Japanese population. Leg Med (Tokyo) (2012) 0.83
Role of nitric oxide system in hydroxyl radical generation in rat striatum due to carbon monoxide poisoning, as determined by microdialysis. Toxicology (2007) 0.82
Central administration of neuromedin U suppresses food intake in chicks. Neurosci Lett (2007) 0.82
Use of the "SMITEST" PSA card to identify the presence of prostate-specific antigen in semen and male urine. Forensic Sci Int (2002) 0.82
Safety and efficacy of S-1 monotherapy in elderly patients with advanced gastric cancer. Gastric Cancer (2010) 0.82
Differential dose response of mTOR signaling to oral administration of leucine in skeletal muscle and liver of rats. Biosci Biotechnol Biochem (2013) 0.82
Nutrition support for head and neck squamous cell carcinoma patients treated with chemoradiotherapy: how often and how long? ISRN Oncol (2012) 0.82
Phase I results from a two-part Phase I/II study of cediranib in combination with mFOLFOX6 in Japanese patients with metastatic colorectal cancer. Invest New Drugs (2011) 0.82
Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients. Cancer Sci (2015) 0.82
Determination of prognostic factors in Japanese patients with advanced gastric cancer using the data from a randomized controlled trial, Japan clinical oncology group 9912. Oncologist (2014) 0.82
Neuropeptide Y content in the hypothalamic paraventricular nucleus responds to fasting and refeeding in broiler chickens. Comp Biochem Physiol A Mol Integr Physiol (2005) 0.81
Postmortem computed tomographic (PMCT) demonstration of fatal hemoptysis by pulmonary tuberculosis--radiological-pathological correlation in a case of rupture of Rasmussen's aneurysm. Radiat Med (2004) 0.81
Effects of interleukin-1beta and prostaglandin E2 on prostaglandin D synthase production in cultivated rat leptomeningeal cells. J Cereb Blood Flow Metab (2004) 0.81
Nontraumatic postmortem computed tomographic demonstration of cerebral gas embolism following cardiopulmonary resuscitation. Jpn J Radiol (2010) 0.81
Insulin mediates the linkage acceleration of muscle protein synthesis, thermogenesis, and heat storage by amino acids. Biochem Biophys Res Commun (2009) 0.81
Intranasal immunization with a non-adjuvanted adhesive protein descended from Pasteurella pneumotropica and its preventive efficacy against opportunistic infection in mice. Vaccine (2013) 0.80
Developmental increases in hypothalamic neuropeptide Y content with the embryonic age of meat- and layer-type chicks. Brain Res (2006) 0.80
Bacterial species-characteristic profiles of molecular species, and the antigenicity of phospholipids and glycolipids in symbiotic Lactobacillus, Staphylococcus and Streptococcus species. Glycoconj J (2012) 0.79
L-DOPA induced extracellular dopamine increases in the ventromedial hypothalamus affects food intake by chickens on a lysine-free diet. Neurosci Lett (2011) 0.79
Comparison of combination chemotherapy with irinotecan and cisplatin regimen administered every 2 or 4 weeks in pretreated patients with unresectable or recurrent gastric cancer: retrospective analysis. Int J Clin Oncol (2010) 0.79
The mechanism underlying the central glucagon-induced hyperglycemia and anorexia in chicks. Comp Biochem Physiol A Mol Integr Physiol (2012) 0.79
Retrospective analysis of S-1 monotherapy in patients with metastatic colorectal cancer after failure to fluoropyrimidine and irinotecan or to fluoropyrimidine, irinotecan and oxaliplatin. Jpn J Clin Oncol (2009) 0.79
Distribution of proglucagon mRNA and GLP-1 in the brainstem of chicks. Comp Biochem Physiol A Mol Integr Physiol (2005) 0.79
Immediate non-traumatic postmortem computed tomographic demonstration of myocardial intravascular gas of the left ventricle: effects from cardiopulmonary resuscitation. Springerplus (2013) 0.79
Postmortem computed tomographic (PMCT) findings of pericardial effusion due to acute aortic dissection. Radiat Med (2005) 0.79
Edaravone inhibits collagen-induced arthritis possibly through suppression of nuclear factor-kappa B. Mol Immunol (2007) 0.79