The fate of skin homografts in man.

PubWeight™: 17.30‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMC 1252734)

Published in J Anat on July 01, 1943

Authors

T Gibson1, P B Medawar

Author Affiliations

1: Mr Clark's Surgical Unit, Glasgow Royal Infirmary.

Associated clinical trials:

Donor-Alloantigen-Reactive Regulatory T Cell (darTreg) Therapy in Renal Transplantation (The ONE Study ) (DART) | NCT02244801

Articles citing this

The behaviour and fate of skin autografts and skin homografts in rabbits: A report to the War Wounds Committee of the Medical Research Council. J Anat (1944) 16.73

A second study of the behaviour and fate of skin homografts in rabbits: A Report to the War Wounds Committee of the Medical Research Council. J Anat (1945) 11.04

Experiences with renal homotransplantation in the human: report of nine cases. J Clin Invest (1955) 6.64

Effect of cortisone on survival of skin homografts in rabbits. Br Med J (1951) 4.98

Observations on the behaviour of the transplanted kidney in dogs. Ann R Coll Surg Engl (1950) 2.68

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br J Exp Pathol (1948) 2.53

Problems involved in the homotransplantation of tissues, with particular reference to skin. Br Med J (1951) 1.41

Medawar's legacy to cellular immunology and clinical transplantation: a commentary on Billingham, Brent and Medawar (1956) 'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance'. Philos Trans R Soc Lond B Biol Sci (2015) 1.40

The immune response to multiple-set skin homografts: an experimental study in man. Ann Surg (1958) 1.22

The rejection of skin homografts in the normal human subject. II. Histological findings. J Clin Invest (1962) 1.13

Chimerism and tolerance in transplantation. Proc Natl Acad Sci U S A (2004) 1.07

The pattern of tissue reactions to autologous and homologous musculofascial transplants. J Exp Med (1952) 1.03

Vascularized composite allograft tolerance across MHC barriers in a large animal model. Am J Transplant (2014) 0.98

Regional lymph node changes induced by cartilage homo- and heterografts in the rabbit. J Anat (1958) 0.97

Histochemical studies on human skin autografts. J Anat (1953) 0.92

Spontaneous restoration of transplantation tolerance after acute rejection. Nat Commun (2015) 0.91

History of clinical transplantation. World J Surg (2000) 0.91

Vascularized composite tissue allotransplantation--state of the art. Clin Transplant (2013) 0.90

Historic landmarks in clinical transplantation: conclusions from the consensus conference at the University of California, Los Angeles. World J Surg (2000) 0.90

Immunosuppression and its complications. Proc R Soc Med (1969) 0.89

The pathology of renal homograft rejection. A review. Am J Pathol (1976) 0.89

Studies on the survival of skin homografts. I. Prolongation of life of full-thickness grafts by the action of streptokinase-streptodornase. Ann Surg (1952) 0.87

Agammaglobulinemia: an approach to homovital transplantation. Ann Surg (1955) 0.86

AN ASSAY OF GRAFT-HOST INTERACTIONS ACROSS STRONG AND WEAK HISTOCOMPATIBILITY BARRIERS IN MICE. J Exp Med (1963) 0.85

Immunity to homologous grafted skin; the relationship between the antigens of blood and skin. Br J Exp Pathol (1946) 0.84

The effect of compound 48/80 on the autograft and homograft reaction. Br J Exp Pathol (1960) 0.83

Immunity to homologous grafted skin; the suppression of cell division in grafts transplanted to immunized animals. Br J Exp Pathol (1946) 0.83

Clinical transplantation: current problems, possible solutions. Philos Trans R Soc Lond B Biol Sci (2005) 0.83

Rapid detection of homologous recombinants in nontransformed human cells. Proc Natl Acad Sci U S A (1994) 0.82

Organ transplantation: a practical triumph and epistemologic collapse. Proc Am Philos Soc (2003) 0.82

Escaping from rejection. Transplantation (2009) 0.80

Transplant tolerance: new insights and strategies for long-term allograft acceptance. Clin Dev Immunol (2013) 0.80

The story of kidney transplantation. Br Med J (1966) 0.80

Pancreas and islet cell transplantation. Best Pract Res Clin Gastroenterol (2002) 0.78

The mystique of organ transplantation. J Am Coll Surg (2005) 0.78

The present position and future prospects of organ transplantation. Ann R Coll Surg Engl (1968) 0.78

The role of antibodies in transplantation. Transplant Rev (Orlando) (2009) 0.78

Peter Brian Medawar: father of transplantation. J Am Coll Surg (1995) 0.78

Lessons and limits of mouse models. Cold Spring Harb Perspect Med (2013) 0.78

Biological factors in tissue transplantation. Postgrad Med J (1962) 0.77

Tolerance induction strategies in vascularized composite allotransplantation: mixed chimerism and novel developments. Clin Dev Immunol (2012) 0.77

Fashioning the immunological self: the biological individuality of F. Macfarlane Burnet. J Hist Biol (2014) 0.76

Historical overview of transplantation. Cold Spring Harb Perspect Med (2013) 0.76

The birth of clinical organ transplantation. J Am Coll Surg (2001) 0.76

In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg (2009) 0.76

Immunogenetic aspects of intracerebral skin transplantation in inbred rats. Am J Pathol (1979) 0.75

Biological aspects of individuality. Ann R Coll Surg Engl (1970) 0.75

The Transplantation of the Kidney. Ulster Med J (1963) 0.75

SKIN homografts in clinical practice. Br Med J (1951) 0.75

Blood at 70: its roots in the history of hematology and its birth. Blood (2015) 0.75

New concepts in alloimmune recognition. Cell Immunol (2007) 0.75

The homograft. Postgrad Med J (1959) 0.75

Surgery: art or science? Birth of organ transplantation. Chirurgie (1998) 0.75

The burn disease: a disease of great value in the cultural heritage of plastic surgery. Ann Burns Fire Disasters (2014) 0.75

Old game, new players: Linking classical theories to new trends in transplant immunology. World J Transplant (2017) 0.75

In search of the Holy Grail (actively acquired immunologic tolerance). Ann Surg (1995) 0.75

The Outlook for Transplantation of the Kidney in Man. Proc R Soc Med (1961) 0.75

Human Split-Thickness Skin Allograft from Brain-Dead Donors. Int J Organ Transplant Med (2016) 0.75

Lister Oration, 1979. Science and service. Ann R Coll Surg Engl (1980) 0.75

Post-operative medical and surgical complications after primary total joint arthroplasty in solid organ transplant recipients: a case series. Int Orthop (2016) 0.75

Beyond the "take-home baby": pregnancy as a modulator of organ-specific immunity in mother and offspring. Semin Immunopathol (2016) 0.75

Articles by these authors

Nature and mode of action of antilymphocytic antiserum. Proc Natl Acad Sci U S A (1966) 7.56

Rate of regeneration of peripheral nerves in man. J Physiol (1943) 3.02

THE CHEMICAL INHIBITION OF FIBRE REGENERATION AND NEUROMA FORMATION IN PERIPHERAL NERVES. J Neurol Psychiatry (1942) 2.38

Further experiments on the action of antilymphocytic antiserum. Proc Natl Acad Sci U S A (1967) 2.31

Notes on the preparation and assay of anti-lymphocytic serum for use in mice. Immunology (1968) 1.96

A note on the specificity of the corneal epithelium. J Anat (1950) 1.59

Cellular immunity and the homograft reaction. Br Med Bull (1967) 1.54

Acquired immunological tolerance of foreign cells is impaired by recombinant interleukin 2 or vitamin A acetate. Proc Natl Acad Sci U S A (1985) 1.53

'Actively acquired tolerance' of foreign cells. 1953. J Immunol (2010) 1.46

Survival of skin heterografts under treatment with antilymphocytic serum. Lancet (1968) 1.39

Characterization of antilymphocytic antibody. Nature (1967) 1.27

T-cell-mediated enhancement of host-versus-graft reactivity in mice fed a diet enriched in vitamin A acetate. Nature (1983) 1.20

'Actively acquired tolerance' of foreign cells. 1953. Transplantation (2003) 1.12

Toxicity of Sulphonamide Drugs to Cells in Vitro. Br Med J (1941) 1.10

Enhancement of specific antitumor immunity in mice fed a diet enriched in vitamin A acetate. Proc Natl Acad Sci U S A (1983) 1.10

Double-blind controlled trial of immunosuppression in the treatment of multiple sclerosis: final report. Lancet (1982) 1.09

Induction of tolerance with antilymphocytic serum. Transplant Proc (1969) 1.06

Supposed lamarckian inheritance of immunological tolerance. Nature (1981) 1.05

Immunosuppressive effects of heterologous antilymphocyte serum in monkeys. Lancet (1970) 1.04

Influence of dendritic cells on tumor growth. Proc Natl Acad Sci U S A (1985) 1.02

Foetal antigens and cancer. Nature (1973) 1.00

Tolerance reconsidered--a critical survey. Transplant Proc (1973) 0.98

In vitro reactivity of lymphoid cells from tolerant mice. Transplant Proc (1973) 0.98

Intensive immunosuppression in patients with disseminated sclerosis. I. Clinical response. Clin Exp Immunol (1975) 0.98

Anti-cancer action of retinoids. Immunology (1981) 0.95

Vulnerability of methylcholanthrene-induced tumours to immunity aroused by syngeneic foetal cells. Nature (1978) 0.90

Retinyl acetate-mediated augmentation of resistance to a transplantable 3-methylcholanthrene-induced fibrosarcoma. The dose response and time course. Transplantation (1984) 0.90

Can fetal antigens be used for prophylactic immunization? Ciba Found Symp (1983) 0.88

T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2. Cell Immunol (1986) 0.88

Tolerance of rat skin grafts in adult mice. Proc Natl Acad Sci U S A (1969) 0.86

Transplantation tolerance. Br Med Bull (1976) 0.86

Further studies on supposed lamarckian inheritance of immunological tolerance. Nature (1982) 0.80

Mechanism of action of antilymphoid antisera. Surg Forum (1966) 0.79

The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1960. Immunological tolerance. Scand J Immunol (1991) 0.78

Fear and DNA. New York Rev Books (1977) 0.78

Proceedings: Implications of the fetal antigen theory for fetal transplantation. Cancer Res (1974) 0.77

Antilymphocyte serum and the induction of tolerance to transplantation antigens. Fed Proc (1970) 0.76

The future of life expectancy. Clin Orthop Relat Res (1985) 0.75

The genetic improvement of man. Australas Ann Med (1969) 0.75

Reflections. J Gen Intern Med (1991) 0.75

Host recognition of fetal antigens: do they induce specific antibodies? Ciba Found Symp (1983) 0.75

Can genetically transmitted obesity be ascribed to an adipose tissue defect? Proc Nutr Soc (1977) 0.75

Fetal and cancer cells: some intriguing links. Hosp Pract (Off Ed) (1982) 0.75

Alteration of the immune response in mice by dietary factors: effects of irradiating, autoclaving and essential fatty acid deficiency of rodent diets [proceedings]. Proc Nutr Soc (1976) 0.75

Reflections. J Gen Intern Med (1990) 0.75

Synergism between cortisol and antilymphocyte serum. I. Observations in murine allograft systems. Ciba Found Study Group (1970) 0.75

Some reflections on science and civilization. Ciba Found Symp (1971) 0.75

Modern trends in plastic surgery. Homografts. Mod Trends Plast Surg (1966) 0.75

Proceedings: Therapeutic aspects of the fetal antigen theory. Br J Surg (1974) 0.75

The scientific conscience. Hosp Pract (1976) 0.75

Is immunological tolerance (non-responsiveness) a consequence of interleukin 2 deficit during the recognition of antigen? Immunol Today (1984) 0.75

A biological analysis of individuality. Clin Orthop Relat Res (1996) 0.75

Retinoids and in vivo immunity to transplantable tumours: a terra relatively incognita. Immunol Today (1984) 0.75

Thoughts on progress. Hosp Pract (1976) 0.75

Homografts. Mod Trends Plast Surg (1966) 0.75