Published in Learn Mem on December 04, 2006
Phasic vs sustained fear in rats and humans: role of the extended amygdala in fear vs anxiety. Neuropsychopharmacology (2010) 5.07
Fear extinction as a model for translational neuroscience: ten years of progress. Annu Rev Psychol (2012) 4.04
Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci (2009) 3.32
Impaired fear inhibition is a biomarker of PTSD but not depression. Depress Anxiety (2010) 2.27
How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD. Am J Psychiatry (2010) 2.24
Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity. Biol Psychiatry (2010) 2.02
Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity. Psychiatry Res (2009) 1.76
Impaired safety signal learning may be a biomarker of PTSD. Neuropharmacology (2011) 1.52
Timing of extinction relative to acquisition: a parametric analysis of fear extinction in humans. Behav Neurosci (2008) 1.45
Attention bias toward threat is associated with exaggerated fear expression and impaired extinction in PTSD. Psychol Med (2011) 1.29
Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures. Depress Anxiety (2011) 1.14
Fear potentiation is associated with hypothalamic-pituitary-adrenal axis function in PTSD. Psychoneuroendocrinology (2009) 1.13
Neural mechanisms of impaired fear inhibition in posttraumatic stress disorder. Front Behav Neurosci (2011) 1.13
Childhood abuse is associated with increased startle reactivity in adulthood. Depress Anxiety (2009) 1.11
Direct comparisons of the size and persistence of anisomycin-induced consolidation and reconsolidation deficits. Learn Mem (2009) 1.09
Genetics of anxiety and trauma-related disorders. Neuroscience (2009) 1.07
Stimulation of the noradrenergic system during memory formation impairs extinction learning but not the disruption of reconsolidation. Neuropsychopharmacology (2011) 1.07
Are fear memories erasable?-reconsolidation of learned fear with fear-relevant and fear-irrelevant stimuli. Front Behav Neurosci (2012) 1.00
Pharmacological enhancement of fear reduction: preclinical models. Br J Pharmacol (2011) 0.99
Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Front Behav Neurosci (2013) 0.98
Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions. Int J Psychophysiol (2014) 0.97
A review on human reinstatement studies: an overview and methodological challenges. Learn Mem (2014) 0.96
Conditioned fear associated phenotypes as robust, translational indices of trauma-, stressor-, and anxiety-related behaviors. Front Psychiatry (2014) 0.91
Is an epigenetic switch the key to persistent extinction? Neurobiol Learn Mem (2011) 0.89
What does it take to demonstrate memory erasure? Theoretical comment on Norrholm et al. (2008). Behav Neurosci (2008) 0.88
Testing the effects of Δ9-THC and D-cycloserine on extinction of conditioned fear in humans. J Psychopharmacol (2012) 0.87
Cortisol suppression by dexamethasone reduces exaggerated fear responses in posttraumatic stress disorder. Psychoneuroendocrinology (2011) 0.87
Versatility of fear-potentiated startle paradigms for assessing human conditioned fear extinction and return of fear. Front Behav Neurosci (2011) 0.84
Development of fear acquisition and extinction in children: effects of age and anxiety. Neurobiol Learn Mem (2013) 0.84
Prior fear conditioning and reward learning interact in fear and reward networks. Front Behav Neurosci (2014) 0.84
Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1. Transl Psychiatry (2012) 0.83
Multimodal assessment of long-term memory recall and reinstatement in a combined cue and context fear conditioning and extinction paradigm in humans. PLoS One (2013) 0.80
Substance Use Attenuates Physiological Responses Associated With PTSD among Individuals with Co-Morbid PTSD and SUDs. J Psychol Psychother (2013) 0.80
Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter. PLoS One (2013) 0.80
Retrieval cues that trigger reconsolidation of associative fear memory are not necessarily an exact replica of the original learning experience. Front Behav Neurosci (2015) 0.80
Human fear extinction and return of fear using reconsolidation update mechanisms: the contribution of on-line expectancy ratings. Neurobiol Learn Mem (2013) 0.79
The CB1 receptor as an important mediator of hedonic reward processing. Neuropsychopharmacology (2014) 0.78
Spontaneous recovery but not reinstatement of the extinguished conditioned eyeblink response in the rat. Behav Neurosci (2011) 0.78
Generalization of fear inhibition by disrupting hippocampal protein synthesis-dependent reconsolidation process. Neuropsychopharmacology (2011) 0.78
Translational neuroscience measures of fear conditioning across development: applications to high-risk children and adolescents. Biol Mood Anxiety Disord (2013) 0.78
The effect of positive mood induction on reducing reinstatement fear: Relevance for long term outcomes of exposure therapy. Behav Res Ther (2015) 0.77
Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines. Psychoneuroendocrinology (2014) 0.77
Generalization of fear-potentiated startle in the presence of auditory cues: a parametric analysis. Front Behav Neurosci (2014) 0.77
Relapse of extinguished fear after exposure to a dangerous context is mitigated by testing in a safe context. Learn Mem (2015) 0.77
Post-extinction conditional stimulus valence predicts reinstatement fear: relevance for long-term outcomes of exposure therapy. Cogn Emot (2014) 0.76
Modification of Fear Memory by Pharmacological and Behavioural Interventions during Reconsolidation. PLoS One (2016) 0.76
Acute nicotine enhances spontaneous recovery of contextual fear and changes c-fos early gene expression in infralimbic cortex, hippocampus, and amygdala. Learn Mem (2016) 0.75
Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy. Behav Res Ther (2016) 0.75
Fear reduction without fear through reinforcement of neural activity that bypasses conscious exposure. Nat Hum Behav (2016) 0.75
Extinction learning in humans: role of the amygdala and vmPFC. Neuron (2004) 8.63
Context and behavioral processes in extinction. Learn Mem (2004) 6.99
The role of the amygdala in fear and anxiety. Annu Rev Neurosci (1992) 6.41
Human amygdala activation during conditioned fear acquisition and extinction: a mixed-trial fMRI study. Neuron (1998) 5.54
The emotion probe. Studies of motivation and attention. Am Psychol (1995) 4.63
Behavioral and neural analysis of extinction. Neuron (2002) 4.53
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci (2002) 4.52
Contextual control of the extinction of conditioned fear: tests for the associative value of the context. J Exp Psychol Anim Behav Process (1983) 3.64
Reinstatement of fear to an extinguished conditioned stimulus. J Exp Psychol Anim Behav Process (1975) 3.41
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala. J Neurosci (1992) 3.40
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
A review of the modulation of the startle reflex by affective states and its application in psychiatry. Clin Neurophysiol (2003) 2.91
Role of conditioned contextual stimuli in reinstatement of extinguished fear. J Exp Psychol Anim Behav Process (1979) 2.78
Effects of D-cycloserine on extinction of conditioned freezing. Behav Neurosci (2003) 2.39
Context modulation of memory for fear extinction in humans. Psychophysiology (2005) 1.95
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology (2005) 1.89
The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav (2002) 1.87
D-cycloserine and the facilitation of extinction of conditioned fear: consequences for reinstatement. Behav Neurosci (2004) 1.75
Reinstatement of conditioned fear in humans is context dependent and impaired in amnesia. Behav Neurosci (2005) 1.59
Fear-potentiated startle conditioning in humans: explicit and contextual cue conditioning following paired versus unpaired training. Psychophysiology (1997) 1.59
Mitogen-activated protein kinase cascade in the basolateral nucleus of amygdala is involved in extinction of fear-potentiated startle. J Neurosci (2001) 1.58
Normal conditioned inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medical prefrontal cortex in rats. Behav Neurosci (1997) 1.55
D-cycloserine facilitates extinction of learned fear: effects on reacquisition and generalized extinction. Biol Psychiatry (2005) 1.53
Fear potentiation and fear inhibition in a human fear-potentiated startle paradigm. Biol Psychiatry (2005) 1.49
Neural circuitry of anxiety: evidence from structural and functional neuroimaging studies. Psychopharmacol Bull (2003) 1.48
Reinstatement of fear responses in human aversive conditioning. Behav Res Ther (2005) 1.44
Reinstatement of fear to an extinguished conditioned stimulus: two roles for context. J Exp Psychol Anim Behav Process (2002) 1.32
Reinstatement of extinguished conditioned responses and negative stimulus valence as a pathway to return of fear in humans. Learn Mem (2004) 1.11
A partial reinforcement extinction effect despite equal rates of reinforcement during Pavlovian conditioning. J Exp Psychol Anim Behav Process (2004) 1.06
Contextual fear-potentiated startle conditioning in humans: replication and extension. Psychophysiology (2001) 0.99
Conditioned odor potentiation of startle in rats. Behav Neurosci (1999) 0.92
Chronic life stress and treatment outcome in agoraphobia with panic attacks. Am J Psychiatry (1993) 0.89
Extinction in fear conditioning: effects on startle modulation and evaluative self-reports. Psychophysiology (1998) 0.88
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry (2004) 5.26
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature (2011) 4.94
Short term outcomes of prostate biopsy in men tested for cancer by prostate specific antigen: prospective evaluation within ProtecT study. BMJ (2012) 4.64
Behavioral and neural analysis of extinction. Neuron (2002) 4.53
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci (2002) 4.52
A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. Am J Psychiatry (2014) 4.25
Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety. Eur J Pharmacol (2003) 4.08
Effects of D-cycloserine on extinction: translation from preclinical to clinical work. Biol Psychiatry (2006) 3.45
Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci (2009) 3.32
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
Applying learning principles to the treatment of post-trauma reactions. Ann N Y Acad Sci (2003) 3.05
Genetic correction of PSA values using sequence variants associated with PSA levels. Sci Transl Med (2010) 2.83
Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci (2004) 2.73
Characterization of Bouveret's syndrome: a comprehensive review of 128 cases. Am J Gastroenterol (2006) 2.58
Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci U S A (2003) 2.56
A significant decline in the American domination of research in gastroenterology with increasing globalization from 1980 to 2005: an analysis of American authorship among 8,251 articles. Am J Gastroenterol (2008) 2.53
Emotion, motivation, and the brain: reflex foundations in animal and human research. Prog Brain Res (2006) 2.52
Impaired fear inhibition is a biomarker of PTSD but not depression. Depress Anxiety (2010) 2.27
Pain symptomatology and pain medication use in civilian PTSD. Pain (2011) 2.16
Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci (2006) 2.10
Regulation of synaptic plasticity genes during consolidation of fear conditioning. J Neurosci (2002) 2.10
Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder. Biol Psychiatry (2012) 2.02
Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity. Biol Psychiatry (2010) 2.02
Role of the extended amygdala in short-duration versus sustained fear: a tribute to Dr. Lennart Heimer. Brain Struct Funct (2008) 1.97
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology (2005) 1.89
The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav (2002) 1.87
Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity. Psychiatry Res (2009) 1.76
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med (2013) 1.74
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A (2010) 1.72
Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction. J Neurosci (2005) 1.72
Conditioned pharmacotherapeutic effects: a preliminary study. Psychosom Med (2009) 1.68
Alterations in diurnal cortisol rhythm and acoustic startle response in nonhuman primates with adverse rearing. Biol Psychiatry (2005) 1.65
Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma. Am J Psychiatry (2014) 1.60
Long-term therapy with aerosolized ribavirin for parainfluenza 3 virus respiratory tract infection in an infant with severe combined immunodeficiency. Pediatr Transplant (2007) 1.54
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. Learn Mem (2004) 1.53
Impaired safety signal learning may be a biomarker of PTSD. Neuropharmacology (2011) 1.52
Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology (2010) 1.51
Fear potentiation and fear inhibition in a human fear-potentiated startle paradigm. Biol Psychiatry (2005) 1.49
Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts. Eur Urol (2009) 1.49
Cognitive behavioral therapy for public-speaking anxiety using virtual reality for exposure. Depress Anxiety (2005) 1.49
Timing of extinction relative to acquisition: a parametric analysis of fear extinction in humans. Behav Neurosci (2008) 1.45
Height and prostate cancer risk: a large nested case-control study (ProtecT) and meta-analysis. Cancer Epidemiol Biomarkers Prev (2008) 1.44
"Hidden" social networks in behavior change interventions. Am J Public Health (2015) 1.41
Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev (2010) 1.40
Dissociable roles for the hippocampus and the amygdala in human cued versus context fear conditioning. J Neurosci (2008) 1.40
Role of the amygdala in fear extinction measured with potentiated startle. Ann N Y Acad Sci (2003) 1.40
Menstrual cycle phase effects on prepulse inhibition of acoustic startle. Psychophysiology (2004) 1.38
Early intervention may prevent the development of posttraumatic stress disorder: a randomized pilot civilian study with modified prolonged exposure. Biol Psychiatry (2012) 1.37
Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial. Arch Gen Psychiatry (2009) 1.35
Return of fear in a human differential conditioning paradigm caused by a return to the original acquistion context. Behav Res Ther (2005) 1.34
PTSD and gene variants: new pathways and new thinking. Neuropharmacology (2011) 1.34
Learning-dependent structural plasticity in the adult olfactory pathway. J Neurosci (2008) 1.34
Brain-derived neurotrophic factor in amygdala-dependent learning. Neuroscientist (2005) 1.31
Contingency awareness and fear inhibition in a human fear-potentiated startle paradigm. Behav Neurosci (2006) 1.30
The effect of gonadal hormones and gender on anxiety and emotional learning. Horm Behav (2006) 1.29
Veterans seeking treatment for posttraumatic stress disorder: what about comorbid chronic pain? J Rehabil Res Dev (2007) 1.29
The Australian Intervention Randomized Control of Rate in Atrial Fibrillation Trial (AIRCRAFT). J Am Coll Cardiol (2003) 1.29
Glutamate receptor antagonist infusions into the basolateral and medial amygdala reveal differential contributions to olfactory vs. context fear conditioning and expression. Learn Mem (2005) 1.28
The role of glutamate and gamma-aminobutyric acid in fear extinction: clinical implications for exposure therapy. Biol Psychiatry (2002) 1.28
Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: moderation by oxytocin receptor gene. Dev Psychopathol (2011) 1.24
AX+, BX- discrimination learning in the fear-potentiated startle paradigm: possible relevance to inhibitory fear learning in extinction. Learn Mem (2004) 1.24
Temporary disruption of fear-potentiated startle following PKMζ inhibition in the amygdala. Nat Neurosci (2011) 1.23
Light-enhanced startle: further pharmacological and behavioral characterization. Psychopharmacology (Berl) (2001) 1.21
Emerging treatments for PTSD. Clin Psychol Rev (2009) 1.21
Involvement of central amygdalar and bed nucleus of the stria terminalis corticotropin-releasing factor in behavioral responses to social defeat. Behav Neurosci (2004) 1.20
Dark-enhanced startle responses and heart rate variability in a traumatized civilian sample: putative sex-specific correlates of posttraumatic stress disorder. Psychosom Med (2012) 1.20
Pharmacological treatments that facilitate extinction of fear: relevance to psychotherapy. NeuroRx (2006) 1.20
Relationship of enhanced norepinephrine activity during memory consolidation to enhanced long-term memory in humans. Am J Psychiatry (2002) 1.18
Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev (2009) 1.18
Olfactory-mediated fear-potentiated startle. Behav Neurosci (2002) 1.18
Neural correlates of attention bias to threat in post-traumatic stress disorder. Biol Psychol (2012) 1.17
Chronic depression: medication (nefazodone) or psychotherapy (CBASP) is effective when the other is not. Arch Gen Psychiatry (2005) 1.17
Daily living with distress and enrichment: the moral experience of families with ventilator-assisted children at home. Pediatrics (2006) 1.17
Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: implications for the neurocircuitry of fear and anxiety. Psychopharmacology (Berl) (2002) 1.16
Effects of the beta-blocker propranolol on cued and contextual fear conditioning in humans. Psychopharmacology (Berl) (2004) 1.16
A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: involvement of nicotinic receptor mechanisms. Schizophr Res (2006) 1.16
Acoustic startle, prepulse inhibition, and fear-potentiated startle measured in rhesus monkeys. Biol Psychiatry (2002) 1.15
White matter integrity in highly traumatized adults with and without post-traumatic stress disorder. Neuropsychopharmacology (2012) 1.14
Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder. J Psychiatr Res (2013) 1.14
Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures. Depress Anxiety (2011) 1.14
The role of neuropeptide Y in the expression and extinction of fear-potentiated startle. J Neurosci (2008) 1.14
Acute thrombosis of the inferior vena cava. Am J Emerg Med (2006) 1.13
Computer-supported cognitive behavioral treatment of anxiety disorders. J Clin Psychol (2004) 1.13