Published in Genes Dev on January 01, 2007
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell (2007) 7.99
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev (2007) 5.83
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature (2009) 5.48
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell (2009) 5.03
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev (2010) 4.75
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest (2009) 4.39
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev (2008) 4.24
Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol (2007) 3.67
Non-coding RNAs as regulators of embryogenesis. Nat Rev Genet (2011) 3.36
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A (2008) 3.33
Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1. Mol Cell (2007) 3.22
Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. Neuron (2008) 3.13
MicroRNA regulatory networks in cardiovascular development. Dev Cell (2010) 3.09
MicroRNA control of muscle development and disease. Curr Opin Cell Biol (2009) 3.04
MicroRNA-206: the skeletal muscle-specific myomiR. Biochim Biophys Acta (2008) 2.64
Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis. Nat Rev Mol Cell Biol (2011) 2.51
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol (2008) 2.39
The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. J Clin Invest (2009) 2.36
MicroRNAs 1, 133, and 206: critical factors of skeletal and cardiac muscle development, function, and disease. Int J Biochem Cell Biol (2009) 2.30
Multilevel regulation of gene expression by microRNAs. Science (2008) 2.28
A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level. Nucleic Acids Res (2009) 2.12
MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. Mol Biol Cell (2010) 1.89
SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control. Nat Struct Mol Biol (2010) 1.78
The role of miRNAs in regulating gene expression networks. J Mol Biol (2013) 1.74
microRNAs and muscle disorders. J Cell Sci (2009) 1.73
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet (2011) 1.69
Evidence of MyomiR network regulation of beta-myosin heavy chain gene expression during skeletal muscle atrophy. Physiol Genomics (2009) 1.62
Tissue-specific splicing factor gene expression signatures. Nucleic Acids Res (2008) 1.49
Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model. J Cell Mol Med (2010) 1.44
Auto- and cross-regulation of the hnRNP L proteins by alternative splicing. Mol Cell Biol (2009) 1.41
Sam68 regulates a set of alternatively spliced exons during neurogenesis. Mol Cell Biol (2008) 1.38
Splicing factor and exon profiling across human tissues. Nucleic Acids Res (2010) 1.37
Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel. Hum Mol Genet (2011) 1.37
Analysis of alternative splicing associated with aging and neurodegeneration in the human brain. Genome Res (2011) 1.35
Autoregulation of Fox protein expression to produce dominant negative splicing factors. RNA (2009) 1.34
MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells. Proc Natl Acad Sci U S A (2007) 1.32
The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration. PLoS One (2011) 1.29
MicroRNAs in skeletal myogenesis. Cell Cycle (2011) 1.26
MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development. Genes Dev (2010) 1.22
microRNA expression during trophectoderm specification. PLoS One (2009) 1.22
Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2. Crit Rev Biochem Mol Biol (2012) 1.20
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins. Mol Cell Biol (2009) 1.20
Vascular smooth muscle phenotypic diversity and function. Physiol Genomics (2010) 1.18
Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation. RNA (2013) 1.17
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression. Mol Cancer (2013) 1.15
Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts. RNA (2011) 1.14
Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression. Brief Funct Genomics (2010) 1.14
Insulin-like growth factor-1 receptor is regulated by microRNA-133 during skeletal myogenesis. PLoS One (2011) 1.13
MicroRNAs-10a and -10b contribute to retinoic acid-induced differentiation of neuroblastoma cells and target the alternative splicing regulatory factor SFRS1 (SF2/ASF). J Biol Chem (2010) 1.11
miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish. Development (2012) 1.10
MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci (2011) 1.10
Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nat Commun (2014) 1.08
De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. PLoS Comput Biol (2014) 1.08
NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression. Am J Physiol Heart Circ Physiol (2010) 1.07
RBM4 down-regulates PTB and antagonizes its activity in muscle cell-specific alternative splicing. J Cell Biol (2011) 1.04
Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes. BMC Genomics (2013) 1.04
Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein. J Biol Chem (2011) 1.01
New insights into functional roles of the polypyrimidine tract-binding protein. Int J Mol Sci (2013) 1.00
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High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression. PLoS One (2010) 0.97
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Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord (2011) 0.93
Expression of human nPTB is limited by extreme suboptimal codon content. PLoS One (2008) 0.92
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The Akt-associated microRNAs. Cell Mol Life Sci (2012) 0.91
MicroRNAs, stem cells and cancer stem cells. World J Stem Cells (2012) 0.91
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MiR-206, a key modulator of skeletal muscle development and disease. Int J Biol Sci (2015) 0.90
Myostatin genotype regulates muscle-specific miRNA expression in mouse pectoralis muscle. BMC Res Notes (2010) 0.88
Identification of differences in microRNA transcriptomes between porcine oxidative and glycolytic skeletal muscles. BMC Mol Biol (2013) 0.88
A role for RNA post-transcriptional regulation in satellite cell activation. Skelet Muscle (2012) 0.88
A role for polypyrimidine tract binding protein in the establishment of focal adhesions. Mol Cell Biol (2009) 0.88
Comparative expression profiles of microRNA in left and right atrial appendages from patients with rheumatic mitral valve disease exhibiting sinus rhythm or atrial fibrillation. J Transl Med (2014) 0.87
Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease. World J Biol Chem (2015) 0.87
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MicroRNA in carcinogenesis & cancer diagnostics: a new paradigm. Indian J Med Res (2013) 0.86
Micro-RNA mediated regulation of proliferation, self-renewal and differentiation of mammalian stem cells. Cell Adh Migr (2009) 0.86
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nat Commun (2015) 0.84
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Alternative splicing switching in stem cell lineages. Front Biol (Beijing) (2013) 0.82
Polypyrimidine tract binding protein (hnRNP I) is possibly a conserved modulator of miRNA-mediated gene regulation. PLoS One (2012) 0.82
Non-coding RNA in apicomplexan parasites. Mol Biochem Parasitol (2010) 0.81
A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart. J Cell Sci (2013) 0.81
Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers. Mol Cell Biol (2015) 0.81
Myomaker, Regulated by MYOD, MYOG and miR-140-3p, Promotes Chicken Myoblast Fusion. Int J Mol Sci (2015) 0.81
Complex interaction between dengue virus replication and expression of miRNA-133a. BMC Infect Dis (2016) 0.80
MicroRNA-regulation of Anopheles gambiae immunity to Plasmodium falciparum infection and midgut microbiota. Dev Comp Immunol (2014) 0.80
A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance. J Cell Sci (2013) 0.80
Identification and profiling of microRNAs and their target genes from developing caprine skeletal Muscle. PLoS One (2014) 0.79
Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5' splice site choice. PLoS Genet (2014) 0.78
Micromanaging alternative splicing during muscle differentiation. Dev Cell (2007) 0.78
Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection? Adv Virol (2016) 0.75
Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing. Elife (2016) 0.75
microRNA133a targets Foxl2 and promotes differentiation of C2C12 into myogenic progenitor cells. DNA Cell Biol (2015) 0.75
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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62
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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
Identification of novel genes coding for small expressed RNAs. Science (2001) 44.44
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
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An extensive class of small RNAs in Caenorhabditis elegans. Science (2001) 34.17
c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res (2005) 18.58
MicroRNA-directed cleavage of HOXB8 mRNA. Science (2004) 18.33
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Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature (2005) 17.17
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MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell (2005) 15.38
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A pancreatic islet-specific microRNA regulates insulin secretion. Nature (2004) 15.02
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Inhibition of translational initiation by Let-7 MicroRNA in human cells. Science (2005) 13.84
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MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16
New microRNAs from mouse and human. RNA (2003) 10.35
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A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell (2005) 9.22
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Muscle-specific microRNA miR-206 promotes muscle differentiation. J Cell Biol (2006) 5.78
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The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. RNA (2012) 1.00
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A role for polypyrimidine tract binding protein in the establishment of focal adhesions. Mol Cell Biol (2009) 0.88
A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Res (2013) 0.85
Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function. Nucleic Acids Res (2013) 0.84
Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure. Nucleic Acids Res (2013) 0.82
MicroRNAs as components of systemic signaling pathways in Drosophila melanogaster. Curr Top Dev Biol (2013) 0.79
Splice isoforms of phosducin-like protein control the expression of heterotrimeric G proteins. J Biol Chem (2013) 0.79
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RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest (2017) 0.75
Correction: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife (2017) 0.75
Corrigendum: Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nat Immunol (2017) 0.75