PubRank

Linzhao Cheng

Author PubWeight™ 121.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007 9.47
2 Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell 2009 8.97
3 HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell 2007 4.81
4 Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 2009 4.22
5 Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 2011 3.58
6 Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 2010 3.53
7 Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood 2011 3.43
8 Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood 2011 3.21
9 Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells 2008 3.14
10 Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 2005 2.81
11 RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood 2013 2.00
12 In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proc Natl Acad Sci U S A 2008 1.99
13 Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther 2003 1.87
14 Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells 2010 1.74
15 HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells 2006 1.66
16 Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Res 2007 1.61
17 Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell 2008 1.60
18 Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood 2011 1.59
19 PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor. Prostate 2006 1.55
20 The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Res 2008 1.43
21 Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet 2004 1.42
22 The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria. Am J Hum Genet 2012 1.40
23 Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol 2003 1.35
24 Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells. Blood 2011 1.34
25 Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood 2002 1.33
26 Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell 2008 1.32
27 Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nat Protoc 2012 1.32
28 Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A 2002 1.26
29 Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells. J Biol Chem 2008 1.26
30 Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Res 2010 1.24
31 Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. J Cell Biol 2010 1.22
32 Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). J Biol Chem 2004 1.20
33 Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells 2006 1.20
34 Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proc Natl Acad Sci U S A 2013 1.18
35 Electrophysiological properties of pluripotent human and mouse embryonic stem cells. Stem Cells 2005 1.17
36 FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells. Br J Haematol 2007 1.12
37 Radiofrequency-enhanced vascular gene transduction and expression for intravascular MR imaging-guided therapy: feasibility study in pigs. Radiology 2005 1.10
38 Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells. Hum Gene Ther 2003 1.09
39 The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. PLoS One 2012 1.09
40 Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation. Stem Cells 2015 1.07
41 An improved method for generating and identifying human induced pluripotent stem cells. Methods Mol Biol 2010 1.07
42 TEL-AML1, expressed from t(12;21) in human acute lymphocytic leukemia, induces acute leukemia in mice. Cancer Res 2002 1.06
43 Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing. Sci Rep 2013 1.06
44 Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models. Prostate 2007 1.05
45 Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Res 2013 1.02
46 Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Res 2009 1.02
47 Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nat Med 2003 1.00
48 In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC). Cancer Immunol Immunother 2008 0.99
49 Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH. Exp Hematol 2008 0.96
50 Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Blood 2014 0.95
51 Molecular imaging and stem cell research. Mol Imaging 2011 0.95
52 Human induced pluripotent stem cell-derived mesenchymal stem cell seeding on calcium phosphate scaffold for bone regeneration. Tissue Eng Part A 2014 0.94
53 Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation. Blood 2005 0.93
54 How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach. Mol Imaging 2007 0.93
55 Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis. Stem Cells 2014 0.91
56 Ethics: China already has clear stem-cell guidelines. Nature 2006 0.91
57 Promise and challenges of human iPSC-based hematologic disease modeling and treatment. Int J Hematol 2012 0.91
58 Concise review: Human cell engineering: cellular reprogramming and genome editing. Stem Cells 2012 0.90
59 Acceleration of G(1) cooperates with core binding factor beta-smooth muscle myosin heavy chain to induce acute leukemia in mice. Cancer Res 2002 0.88
60 Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Stem Cells Dev 2012 0.88
61 Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality. Hum Mutat 2014 0.87
62 In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals. Blood 2003 0.87
63 Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation. Blood 2002 0.86
64 Culture of human embryonic stem cells on human and mouse feeder cells. Methods Mol Biol 2006 0.86
65 High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system. J Invest Dermatol 2004 0.84
66 The dazzle in germ cell differentiation. J Mol Cell Biol 2009 0.84
67 Detection of dual-gene expression in arteries using an optical imaging method. J Biomed Opt 2004 0.83
68 Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells 2014 0.83
69 Lentiviral gene transduction of mouse and human stem cells. Methods Mol Biol 2008 0.83
70 Potential of human induced pluripotent stem cells derived from blood and other postnatal cell types. Regen Med 2010 0.83
71 Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells. Stem Cells Transl Med 2013 0.79
72 Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Transl Med 2013 0.79
73 Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013. Ann Biomed Eng 2013 0.79
74 Multiple, interconvertible states of human pluripotent stem cells. Cell Stem Cell 2010 0.79
75 And then there were none: no need for pluripotency factors to induce reprogramming. Cell Stem Cell 2013 0.78
76 Generation and homing of iPSC-derived hematopoietic cells in vivo. Mol Ther 2013 0.78
77 Double knockouts in human embryonic stem cells. Cell Res 2010 0.77
78 Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood 2013 0.75
79 Making lentiviral vectors more powerful and universal. Discov Med 2003 0.75