Published in Brain Res Dev Brain Res on October 21, 1991
The many faces of insulin-like peptide signalling in the brain. Nat Rev Neurosci (2012) 1.87
Insulin-like growth factor-I (IGF-I) inhibits neuronal apoptosis in the developing cerebral cortex in vivo. Int J Dev Neurosci (2007) 0.92
IRS-2 Deficiency impairs NMDA receptor-dependent long-term potentiation. Cereb Cortex (2011) 0.87
Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor I. Proc Natl Acad Sci U S A (1993) 0.82
Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J Neurosci (2001) 2.85
Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med (2002) 2.13
Circulating insulin-like growth factor I mediates effects of exercise on the brain. J Neurosci (2000) 2.11
Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J Neurosci (2001) 1.99
Insulin-like growth factor I is required for vessel remodeling in the adult brain. Proc Natl Acad Sci U S A (2004) 1.75
Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects. Mol Psychiatry (2007) 1.25
Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis. Neurobiol Aging (2005) 1.20
Neurodegeneration is associated to changes in serum insulin-like growth factors. Neurobiol Dis (2000) 1.12
Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B). J Biol Chem (2000) 1.05
Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study. J Neurocytol (1997) 0.98
Molecular characterization of a new PToV strain. Evolutionary implications. Virus Res (2009) 0.96
Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia. Proc Natl Acad Sci U S A (1998) 0.96
IGF-I and the aging mammalian brain. Exp Gerontol (2010) 0.95
Emerging roles of insulin-like growth factor-I in the adult brain. Growth Horm IGF Res (2007) 0.93
Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain. Brain Res (1991) 0.92
Expression of insulin-like growth factor I by astrocytes in response to injury. Brain Res (1992) 0.92
Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation. Neuroscience (1996) 0.90
Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration. Biomaterials (2004) 0.90
Cryopreservation of human brain tissue. Exp Neurol (1990) 0.90
Insulin-like growth factor I treatment for cerebellar ataxia: addressing a common pathway in the pathological cascade? Brain Res Brain Res Rev (2005) 0.89
Neuroprotective actions of peripherally administered insulin-like growth factor I in the injured olivo-cerebellar pathway. Eur J Neurosci (1999) 0.89
Corticotropin releasing factor (CRF): immunocytochemical localization and radioimmunoassay (RIA). Life Sci (1982) 0.89
Role of astroglia and insulin-like growth factor-I in gonadal hormone-dependent synaptic plasticity. Brain Res Bull (1997) 0.88
Astrocytic shape and glial fibrillary acidic protein immunoreactivity are modified by estradiol in primary rat hypothalamic cultures. Brain Res Dev Brain Res (1989) 0.88
Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice. Transl Psychiatry (2013) 0.87
Endocrine-dependent accumulation of IGF-I by hypothalamic glia. Neuroreport (1996) 0.87
Basic fibroblast growth factor modulates insulin-like growth factor-I, its receptor, and its binding proteins in hypothalamic cell cultures. Endocrinology (1992) 0.86
Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology. Mol Psychiatry (2011) 0.85
Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling. Mol Cell Neurosci (2003) 0.85
Inhibition of growth of a prolactin and growth hormone-secreting pituitary tumor in rats by D-tryptophan-6 analog of luteinizing hormone-releasing hormone. Proc Natl Acad Sci U S A (1985) 0.84
Involvement of protein kinase C and nitric oxide in the modulation by insulin-like growth factor-I of glutamate-induced GABA release in the cerebellum. Neuroscience (1996) 0.84
Orthograde transport and release of insulin-like growth factor I from the inferior olive to the cerebellum. J Neurosci Res (1993) 0.84
Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotide. Proc Natl Acad Sci U S A (1994) 0.84
Gonadal steroids as promoters of neuro-glial plasticity. Psychoneuroendocrinology (1994) 0.83
Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor I. Proc Natl Acad Sci U S A (1993) 0.82
Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult. Neuroscience (1997) 0.81
Inhibition of growth of a prolactin-secreting pituitary tumor in rats by analogs of luteinizing hormone-releasing hormone and somatostatin. Proc Natl Acad Sci U S A (1983) 0.81
Insulin-like growth factor I potentiates kainate receptors through a phosphatidylinositol 3-kinase dependent pathway. Neuroreport (2001) 0.80
Estradiol promotes cell shape changes and glial fibrillary acidic protein redistribution in hypothalamic astrocytes in vitro: a neuronal-mediated effect. Glia (1992) 0.80
Synthesis and biological properties of ovine corticotropin-releasing factor (CRF). Life Sci (1982) 0.80
Estradiol modulates insulin-like growth factor I receptors and binding proteins in neurons from the hypothalamus. J Neuroendocrinol (1993) 0.79
Estradiol promotion of changes in the morphology of astroglia growing in culture depends on the expression of polysialic acid of neural membranes. Glia (1995) 0.79
The effects of estradiol on the growth patterns of estrogen receptor-positive hypothalamic cell lines. Endocrinology (1990) 0.79
Insulin-like growth factor I is an afferent trophic signal that modulates calbindin-28kD in adult Purkinje cells. J Neurosci Res (1995) 0.79
Early brain amyloidosis in APP/PS1 mice with serum insulin-like growth factor-I deficiency. Neurosci Lett (2011) 0.78
Immunolocalization of a novel cholesteryl ester hydrolase in the endoplasmic reticulum of murine and human hepatocytes. Hepatology (2001) 0.78
Independent alterations in the central and peripheral somatosensory pathways in rat diabetic neuropathy. Neuroscience (2009) 0.78
Enhancement of lymphocyte proliferation, interleukin-2 production and NK activity by inmunoferon (AM-3), a fungal immunomodulator: variations in normal and immunosuppressed mice. Int J Immunopharmacol (1986) 0.78
D-Trp6-luteinizing hormone-releasing hormone inhibits sulpiride-induced hyperprolactinemia in normal men. J Clin Endocrinol Metab (1987) 0.77
Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus. Horm Res (1996) 0.77
Chronic intraventricular infusion of glial cell line-derived neurotrophic factor (GDNF) rescues some cerebellar Purkinje cells from heredodegeneration. Exp Neurol (2001) 0.77
Effect of [D-Trp6]LHRH infusion on prolactin secretion by perifused rat pituitary cells. Regul Pept (1987) 0.75
Specific alterations of the insulin-like growth factor I system in the cerebellum of diabetic rats. Endocrinology (1996) 0.75
Effect of an antagonistic analog of LH-RH on haloperidol-induced hyperprolactinemia in female rats. Peptides (1986) 0.75
Radioimmunoassay of CRF-like material in rat plasma: validation of the method. Proc Soc Exp Biol Med (1983) 0.75
Growth factors and the developmental neurobiology of the hypothalamus. Acta Paediatr Scand Suppl (1990) 0.75
Antiserum to LH-RH blocks haloperidol-induced hyperprolactinemia in female rats. Neuroendocrinology (1985) 0.75
In vivo effect of isoprinosine on interleukin-2 production, lymphocyte mitogenesis and NK activity in normal and cyclophosphamide immunosuppressed mice. Int J Immunopharmacol (1986) 0.75
Corticosterone-releasing activity of immune mediators. Life Sci (1987) 0.75
Stimulation of insulin secretion by corticotropin-releasing factor (CRF) in anesthetized rats. Peptides (1984) 0.75
Synthesis and biological activity of a cyclic pseudohexapeptide analog of somatostatin. Biochem Biophys Res Commun (1984) 0.75
Isoprinosine restores in vitro T lymphocyte functions of cyclophosphamide immunosuppressed mice. Int J Immunopharmacol (1987) 0.75