Published in Neuropathol Appl Neurobiol on February 01, 2007
The GSK3 hypothesis of Alzheimer's disease. J Neurochem (2007) 3.16
Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice. Am J Pathol (2008) 1.65
HDAC6 regulates mitochondrial transport in hippocampal neurons. PLoS One (2010) 1.63
NOA: a novel Network Ontology Analysis method. Nucleic Acids Res (2011) 1.60
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice. Am J Pathol (2007) 1.26
Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease. Neurotherapeutics (2008) 1.19
GSK-3β, a pivotal kinase in Alzheimer disease. Front Mol Neurosci (2014) 1.18
Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology. Mol Neurodegener (2007) 1.13
HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs? Mol Neurodegener (2013) 1.12
GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals. Neurobiol Dis (2008) 1.10
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol Neurodegener (2012) 1.10
GSK3 and Alzheimer's Disease: Facts and Fiction…. Front Mol Neurosci (2011) 1.09
WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β. Cell Death Differ (2011) 1.05
The dynamic role of beta-catenin in synaptic plasticity. Neuropharmacology (2011) 1.04
Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease. Neurobiol Dis (2011) 1.04
Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD. J Neurochem (2009) 1.03
Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling. PLoS One (2013) 0.97
PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia. Acta Neuropathol (2015) 0.97
Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation. Genes Brain Behav (2008) 0.95
Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment. Int J Alzheimers Dis (2011) 0.94
Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level. Mol Neurodegener (2012) 0.90
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms. Biochemistry (2011) 0.90
CDK5 activator protein p25 preferentially binds and activates GSK3β. Proc Natl Acad Sci U S A (2014) 0.89
Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. Free Radic Biol Med (2013) 0.89
Recent developments of protein kinase inhibitors as potential AD therapeutics. Front Cell Neurosci (2013) 0.89
Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease. Int J Alzheimers Dis (2012) 0.88
GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration. Front Mol Neurosci (2011) 0.88
Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization. Biochemistry (2009) 0.87
Therapy for Alzheimer's Disease: How Effective are Current Treatments? Ther Adv Neurol Disord (2009) 0.85
Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiol Aging (2011) 0.85
β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. J Neurochem (2010) 0.85
Accelerated human mutant tau aggregation by knocking out murine tau in a transgenic mouse model. Am J Pathol (2011) 0.85
Neurofibrillary tangles and the deposition of a beta amyloid peptide with a novel N-terminal epitope in the brains of wild Tsushima leopard cats. PLoS One (2012) 0.84
Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures. Neurobiol Dis (2008) 0.83
Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer's disease. J Neural Transm (Vienna) (2015) 0.82
Anaesthesia generates neuronal insulin resistance by inducing hypothermia. BMC Neurosci (2008) 0.82
Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway. Int J Alzheimers Dis (2011) 0.82
Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. J Biol Chem (2013) 0.82
Potential therapeutic strategies for Alzheimer's disease targeting or beyond β-amyloid: insights from clinical trials. Biomed Res Int (2014) 0.81
Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy. Neurodegener Dis (2012) 0.80
GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons. PLoS One (2015) 0.79
Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation. Sci Rep (2015) 0.79
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent. Neurobiol Aging (2014) 0.79
Glycogen synthase kinase-3β: a mediator of inflammation in Alzheimer's disease? Int J Alzheimers Dis (2011) 0.79
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. Angew Chem Int Ed Engl (2016) 0.78
Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice. Front Aging Neurosci (2014) 0.77
Treating the lesions, not the disease. Am J Pathol (2007) 0.77
Synergistic effects of GSK-3β and HDAC inhibitors in intracerebroventricular streptozotocin-induced cognitive deficits in rats. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.77
GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity. Mol Cell Neurosci (2015) 0.77
Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis (2012) 0.77
Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer's disease. Cell Mol Life Sci (2016) 0.75
GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions. Cell Death Dis (2016) 0.75
Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease. Sci Rep (2017) 0.75
Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer's disease. Sci Rep (2017) 0.75
An endothelial link between the benefits of physical exercise in dementia. J Cereb Blood Flow Metab (2017) 0.75
Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections. Br Dent J (2010) 2.14
Post-implant neuropathy of the trigeminal nerve. A case series. Br Dent J (2012) 1.47
[A persistent ulceration after a fortuitous BCG revaccination]. Ann Dermatol Venereol (2004) 1.37
Performance of the Now Malaria rapid diagnostic test with returned travellers: a 2-year retrospective study in a French teaching hospital. Clin Microbiol Infect (2005) 1.03
The complex relationship between soluble and insoluble tau in tauopathies revealed by efficient dephosphorylation and specific antibodies. FEBS Lett (2002) 1.01
Prognostic value of serum acute-phase proteins in dogs with parvoviral enteritis. J Small Anim Pract (2010) 1.00
The changing pattern of Fusobacterium infections in humans: recent experience with Fusobacterium bacteraemia. Clin Microbiol Infect (2006) 0.91
Rupture of the uterus. Int J Gynaecol Obstet (1995) 0.90
Evaluation of trigeminal nerve injuries in relation to third molar surgery in a prospective patient cohort. Recommendations for prevention. Int J Oral Maxillofac Surg (2012) 0.89
Validation of a clinical guideline on prevention of venous thromboembolism in medical inpatients: a before-and-after study with systematic ultrasound examination. J Intern Med (2004) 0.89
Cryptococcosis in sarcoidosis: cryptOsarc, a comparative study of 18 cases. QJM (2013) 0.87
A retrospective study on the reproductive outcome of the septate uterus corrected by hysteroscopic metroplasty. Int J Gynaecol Obstet (2002) 0.85
Managing iatrogenic trigeminal nerve injury: a case series and review of the literature. Int J Oral Maxillofac Surg (2012) 0.84
Laparoscopy for diagnosis and treatment of acute abdominal pain. J Laparoendosc Adv Surg Tech A (2000) 0.83
Olanzapine versus placebo for out-patients with anorexia nervosa. Psychol Med (2011) 0.83
Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect (2013) 0.83
Aetiological role of viruses in puppies with diarrhoea. Vet Rec (2007) 0.81
Seroprevalence of Ehrlichia canis antibodies among dogs in Turkey. Vet Rec (2001) 0.81
UK dentists' experience of iatrogenic trigeminal nerve injuries in relation to routine dental procedures: why, when and how often? Br Dent J (2013) 0.81
Fryns anophthalmia-plus syndrome with hypoplastic adrenal glands. Genet Couns (2008) 0.80
[Staphylococcus aureus meningitis with intermediate sensitivity to glycopeptides. Therapeutic indications]. Presse Med (2003) 0.79
Investigation of in vivo radioprotective and in vitro antioxidant and antimicrobial activity of garlic (Allum sativum). Eur Rev Med Pharmacol Sci (2012) 0.79
Inflammatory and oxidative biomarkers of disease severity in dogs with parvoviral enteritis. J Small Anim Pract (2014) 0.79
Peste des petits ruminants outbreak in western Turkey. Vet Rec (2005) 0.78
Effect of experimental endotoxemia on thrombelastography parameters, secondary and tertiary hemostasis in dogs. J Vet Intern Med (2011) 0.78
Prevalence of antibodies to bovine respiratory viruses in cattle infected with bovine immunodeficiency virus. Vet Rec (2008) 0.78
Laparoscopic cholecystectomy for symptomatic gallstones in diabetic patients. J Laparoendosc Adv Surg Tech A (2001) 0.77
Frequency of recipient-derived chimerism and relationship with acute rejection and HLA tissue typing in transplanted livers. Transplant Proc (2006) 0.77
Canine coronavirus infection in Turkish dog population. J Vet Med B Infect Dis Vet Public Health (2004) 0.77
The effects of dimethylsulfoxide in experimental obstructive jaundice. Acta Chir Belg (2003) 0.77
The effects of Losartan on oxidative stress and inflammation in non-diabetic patients undergoing chronic hemodialysis. Eur Rev Med Pharmacol Sci (2013) 0.76
Cytogenetic abnormalities in serous papillary adenocarcinoma of the ovary. Eur J Gynaecol Oncol (2004) 0.76
Community-acquired invasive aspergillosis and outdoor filamentous fungal spore load: a relationship? Clin Microbiol Infect (2011) 0.76
A comparative study of the effect of icodextrin based peritoneal dialysis and hemodialysis on lipid metabolism. Indian J Nephrol (2013) 0.75
A case series of trigeminal nerve injuries caused by periapical lesions of mandibular teeth. Br Dent J (2017) 0.75
Prenatal diagnosis of mosaicism identified in amniotic fluid cell cultures. Genet Couns (2006) 0.75
Submucosal leiomyoma of the uterus incorporated into the fetal membranes and mimicking a placental neoplasm: a case report. Placenta (2003) 0.75
[Empirical treatment of bacteriemias]. Med Mal Infect (2004) 0.75
Mucinous cystadenoma in a female patient with 45,X/46,XY karyotype. Clin Exp Obstet Gynecol (2008) 0.75
[Brucella bacteremia reactivation 70 years after the primary infection]. Med Mal Infect (2009) 0.75
Dilated cardiomyopathy in a patient with 22q11.2 microdeletion syndrome. Genet Couns (2013) 0.75
Fetal survival despite unrecognized uterine rupture resulting from previous unknown corporeal scar. Arch Gynecol Obstet (2001) 0.75
Two cases with partial trisomy 9: cytogenetic and clinical findings. Genet Couns (2010) 0.75
Partial trisomy (11;22) syndrome with manifestations of Goldenhar sequence due to maternal balanced t(11;22). Genet Couns (2006) 0.75
Localization of root canal orifices in mandibular second molars in relation to occlusal dimension. Int Endod J (2009) 0.75
Cytogenetic findings and clinical outcomes of adult acute myeloid leukaemia patients. Clin Exp Med (2007) 0.75
Seroepidemiological survey of Rhodoccocus equi infection in asymptomatic horses from Bursa, Izmir and Istanbul provinces, Turkey. Comp Immunol Microbiol Infect Dis (2006) 0.75
[Vaccination practices following the end of compulsory BCG vaccination. A cross-sectional survey of general practitioners and pediatricians]. Arch Pediatr (2009) 0.75
Subacute tuberculous otitis media complicated by petrositis and meningitis. Rev Laryngol Otol Rhinol (Bord) (2012) 0.75
[Immune reconstitution syndrome and mycobacterial disease during highly active antiretroviral therapy. Retrospective study of six cases]. Presse Med (2005) 0.75
Cannabinoid receptor CB1-immunoreactive nerve fibres in painful and non-painful human tooth pulp. J Clin Neurosci (2010) 0.75
Ozonation of synthetic versus natural textile tannins: recalcitrance and toxicity towards Phaeodactylum tricornutum. Water Sci Technol (2007) 0.75
Detection of identical unbalanced karyotype in two consequent fetuses due to a maternal pericentric inversion of chromosome 18. J Obstet Gynaecol (2012) 0.75
[Erythema multiforme: what is your diagnosis? Measles]. Med Mal Infect (2013) 0.75
Development of collaterals in intermittent and permanent ischemia of the liver. HPB Surg (1996) 0.75
[Subcutaneous abcesses due to Mycobacterium avium due to a reconstitution syndrome in AIDS patients]. Med Mal Infect (2006) 0.75
[Severe infection following arteriotomy with Angio-Seal]. Med Mal Infect (2009) 0.75
Posttransplant lymphoproliferative disorders in liver recipients treated with OKT3 or ALG induction immunosuppression. Transplant Proc (1993) 0.75