Published in J Neurosci on January 24, 2007
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. Neuron (2008) 2.94
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci (2011) 2.90
Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov (2009) 2.88
Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nat Neurosci (2010) 2.40
Transient receptor potential channels as therapeutic targets. Nat Rev Drug Discov (2011) 2.25
TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. Nat Neurosci (2010) 2.06
Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. J Neurosci (2011) 1.51
The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor. Br J Pharmacol (2008) 1.48
TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. PLoS One (2009) 1.30
TRPV1-null mice are protected from diet-induced obesity. FEBS Lett (2008) 1.27
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The endocannabinoid system in anxiety, fear memory and habituation. J Psychopharmacol (2011) 1.21
TRPV1 channels control synaptic plasticity in the developing superior colliculus. J Physiol (2009) 1.17
Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. Learn Mem (2009) 1.16
Polymodal activation of the endocannabinoid system in the extended amygdala. Nat Neurosci (2011) 1.15
Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs. Curr Neuropharmacol (2015) 1.11
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin. Nat Commun (2011) 1.03
The complications of promiscuity: endocannabinoid action and metabolism. Br J Pharmacol (2007) 1.02
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TRP channels and analgesia. Life Sci (2012) 0.99
Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. FASEB J (2008) 0.99
Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C. Mol Pain (2009) 0.99
The unsilent majority-TRPV1 drives "spontaneous" transmission of unmyelinated primary afferents within cardiorespiratory NTS. Am J Physiol Regul Integr Comp Physiol (2012) 0.98
TRPV1: a stress response protein in the central nervous system. Am J Neurodegener Dis (2012) 0.98
Endocannabinoid system and synaptic plasticity: implications for emotional responses. Neural Plast (2007) 0.97
The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus. Front Behav Neurosci (2011) 0.96
TRPV1: a target for next generation analgesics. Curr Neuropharmacol (2008) 0.95
Endocannabinoid-mediated synaptic plasticity and addiction-related behavior. Neuropharmacology (2011) 0.94
Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacology (Berl) (2009) 0.94
Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. BMC Pharmacol (2011) 0.94
Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus (2013) 0.94
Endocannabinoid-dependent LTD in a nociceptive synapse requires activation of a presynaptic TRPV-like receptor. J Neurophysiol (2010) 0.93
Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. J Neurosci (2015) 0.91
Antiaversive effects of cannabinoids: is the periaqueductal gray involved? Neural Plast (2008) 0.91
Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. Front Behav Neurosci (2011) 0.91
Anandamide serves two masters in the brain. Nat Neurosci (2010) 0.89
Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. PLoS One (2011) 0.89
TRPV1 channel-mediated bilateral allodynia induced by unilateral masseter muscle inflammation in rats. Mol Pain (2013) 0.87
Opposing roles for cannabinoid receptor type-1 (CB₁) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats. Neuropsychopharmacology (2011) 0.87
Hyperactive when young, hypoactive and overweight when aged: connecting the dots in the story about locomotor activity, body mass, and aging in Trpv1 knockout mice. Aging (Albany NY) (2011) 0.86
Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity. Neural Plast (2016) 0.86
Compartment-specific modulation of GABAergic synaptic transmission by TRPV1 channels in the dentate gyrus. J Neurosci (2014) 0.85
A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. Hippocampus (2010) 0.85
Ancient Anxiety Pathways Influence Drosophila Defense Behaviors. Curr Biol (2016) 0.83
Acute heat-evoked temperature sensation is impaired but not abolished in mice lacking TRPV1 and TRPV3 channels. PLoS One (2014) 0.83
Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. Hippocampus (2014) 0.83
TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision. Cells (2014) 0.82
Endocannabinoid System and TRPV1 Receptors in the Dorsal Hippocampus of the Rats Modulate Anxiety-like Behaviors. Iran J Basic Med Sci (2012) 0.81
Bi-directional effect of cholecystokinin receptor-2 overexpression on stress-triggered fear memory and anxiety in the mouse. PLoS One (2010) 0.81
In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liability. Prostaglandins Other Lipid Mediat (2009) 0.81
No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex. Mol Brain (2014) 0.81
2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons. Psychopharmacology (Berl) (2015) 0.79
Medial prefrontal cortex Transient Receptor Potential Vanilloid Type 1 (TRPV1) in the expression of contextual fear conditioning in Wistar rats. Psychopharmacology (Berl) (2013) 0.79
Oxytocin Stimulates Extracellular Ca(2+) Influx Through TRPV2 Channels in Hypothalamic Neurons to Exert Its Anxiolytic Effects. Neuropsychopharmacology (2015) 0.78
Toward a translational approach to targeting the endocannabinoid system in posttraumatic stress disorder: a critical review of preclinical research. Biol Psychol (2014) 0.78
Morphine Reduces Expression of TRPV1 Receptors in the Amygdala but not in the Hippocampus of Male Rats. Iran J Med Sci (2014) 0.78
Serotonin stimulates lateral habenula via activation of the post-synaptic serotonin 2/3 receptors and transient receptor potential channels. Neuropharmacology (2015) 0.78
Transient receptor potential vanilloid type 1 channel may modulate opioid reward. Neuropsychopharmacology (2014) 0.78
Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission. Neurosci Biobehav Rev (2016) 0.78
Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives. J Med Chem (2014) 0.76
CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation. PLoS One (2016) 0.76
The endocannabinoid system as a target for novel anxiolytic drugs. Neurosci Biobehav Rev (2017) 0.75
Modulation of innate and learned sexual behaviors by the TRP channel Painless expressed in the fruit fly brain: behavioral genetic analysis and its implications. Front Behav Neurosci (2014) 0.75
TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons. Pflugers Arch (2015) 0.75
Visualization by high resolution immunoelectron microscopy of the transient receptor potential vanilloid-1 at inhibitory synapses of the mouse dentate gyrus. PLoS One (2015) 0.75
Cannabinoid Modulation of Memory Consolidation in Rats: Beyond the Role of Cannabinoid Receptor Subtype 1. Front Pharmacol (2017) 0.75
Cannabinoids and Vanilloids in Schizophrenia: Neurophysiological Evidence and Directions for Basic Research. Front Pharmacol (2017) 0.75
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus. Nat Commun (2017) 0.75
Inhibition of TRPV1 channels enables long-term potentiation in the entorhinal cortex. Pflugers Arch (2016) 0.75
Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. Psychopharmacology (Berl) (2012) 0.75
Stress and the brain: from adaptation to disease. Nat Rev Neurosci (2005) 9.48
Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain. Nat Methods (2007) 8.32
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 7.19
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science (2003) 5.22
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci (2012) 4.71
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet (2007) 4.54
Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat Neurosci (2009) 4.53
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet (2004) 3.91
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 3.62
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest (2008) 3.13
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J Biol Chem (2004) 2.91
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab (2008) 2.91
The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev (2005) 2.90
Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci (2003) 2.79
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci (2007) 2.78
Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nat Rev Drug Discov (2010) 2.68
The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest (2004) 2.52
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet (2010) 2.46
RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell (2007) 2.34
Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21
Genome-wide association study of major recurrent depression in the U.K. population. Am J Psychiatry (2010) 2.17
Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nat Neurosci (2012) 2.15
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Arch Gen Psychiatry (2011) 2.09
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol (2007) 2.08
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors. Trends Neurosci (2012) 2.00
Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol (2002) 1.97
Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice. Psychoneuroendocrinology (2013) 1.96
Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science (2002) 1.93
Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity. Arch Gen Psychiatry (2009) 1.88
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls. Eur J Neurosci (2008) 1.88
Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks. Biol Psychiatry (2009) 1.85
Development of the brain's default mode network from wakefulness to slow wave sleep. Cereb Cortex (2011) 1.79
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet (2008) 1.78
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. Nat Neurosci (2009) 1.77
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain (2010) 1.77
Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling. J Neurosci (2004) 1.70
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat Med (2007) 1.69
Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. Neuropharmacology (2007) 1.68
Elevated cerebrospinal fluid and blood concentrations of oxytocin following its intranasal administration in humans. Sci Rep (2013) 1.67
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (2011) 1.64
Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology (2008) 1.63
Polymorphisms of the glucocorticoid receptor gene and major depression. Biol Psychiatry (2006) 1.62
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. PLoS One (2010) 1.62
EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units. Eur J Hum Genet (2010) 1.62
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects. Science (2009) 1.61
Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biol Psychiatry (2005) 1.61
An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. Gastroenterology (2003) 1.60
The Munich vulnerability study on affective disorders: premorbid polysomnographic profile of affected high-risk probands. Biol Psychiatry (2005) 1.57
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron (2008) 1.57
GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment. Am J Psychiatry (2002) 1.56
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited. Front Neuroendocrinol (2004) 1.54
Increased stress reactivity is associated with reduced hippocampal activity and neuronal integrity along with changes in energy metabolism. Eur J Neurosci (2012) 1.54
The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci (2012) 1.53
Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons. J Neurosci (2004) 1.52
The combined dexamethasone/CRH test as a potential surrogate marker in depression. Prog Neuropsychopharmacol Biol Psychiatry (2005) 1.52
Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites. Nature (2002) 1.52
A mouse model of posttraumatic stress disorder that distinguishes between conditioned and sensitised fear. J Psychiatr Res (2006) 1.51
The endocannabinoid system drives neural progenitor proliferation. FASEB J (2005) 1.51
Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. Psychopharmacology (Berl) (2010) 1.49
Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission. J Neurosci (2006) 1.48
Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways. Mol Endocrinol (2002) 1.47
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A (2008) 1.47
Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. J Psychiatr Res (2008) 1.45
Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker? Biol Psychiatry (2006) 1.44
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Hum Mol Genet (2006) 1.42
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Eur J Neurosci (2009) 1.42
Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse. Learn Mem (2003) 1.42
Infrared-guided laser stimulation of neurons in brain slices. Sci STKE (2002) 1.40
Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. J Neurosci (2005) 1.40
Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments. Anesthesiology (2015) 1.39