Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis.

PubWeight™: 1.32‹?› | Rank: Top 10%

🔗 View Article (PMC 1794524)

Published in Arthritis Res Ther on January 01, 2006

Authors

Kutty Selva Nandakumar1, Rikard Holmdahl

Author Affiliations

1: Medical Inflammation Research, Lund University, Lund 22184, Sweden. nan@med.lu.se

Articles citing this

IL-17-producing T cells can augment autoantibody-induced arthritis. Proc Natl Acad Sci U S A (2009) 1.22

Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils. J Immunol (2014) 1.19

Inflammatory cytokine expression is associated with chikungunya virus resolution and symptom severity. PLoS Negl Trop Dis (2011) 1.12

Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice. J Immunol (2011) 1.10

Neutrophil extracellular chromatin traps connect innate immune response to autoimmunity. Semin Immunopathol (2013) 0.99

Vav/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis. Arthritis Rheum (2008) 0.94

Porphyromonas gingivalis peptidylarginine deiminase, a key contributor in the pathogenesis of experimental periodontal disease and experimental arthritis. PLoS One (2014) 0.90

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease. Infect Immun (2008) 0.90

Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice. Arthritis Rheum (2011) 0.90

Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement. Arthritis Res Ther (2010) 0.89

A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis. PLoS One (2010) 0.88

Evaluation of a candidate anti-arthritic drug using the mouse collagen antibody induced arthritis model and clinically relevant biomarkers. Am J Transl Res (2013) 0.87

Molecular mechanisms involved in the pathogenesis of alphavirus-induced arthritis. Biomed Res Int (2013) 0.85

Anti-type II collagen immune complex-induced granulocyte reactivity is associated with joint erosions in RA patients with anti-collagen antibodies. Arthritis Res Ther (2015) 0.84

Characterization of a novel and spontaneous mouse model of inflammatory arthritis. Arthritis Res Ther (2011) 0.83

Saposin C coupled lipid nanovesicles specifically target arthritic mouse joints for optical imaging of disease severity. PLoS One (2012) 0.83

Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice. Arthritis Res Ther (2012) 0.82

Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases. J R Soc Interface (2013) 0.81

Premolis semirufa (Walker, 1856) envenomation, disease affecting rubber tappers of the Amazon: searching for caterpillar-bristles toxic components. PLoS Negl Trop Dis (2012) 0.81

Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis. Arthritis Res Ther (2015) 0.80

Exogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model. J Transl Med (2014) 0.79

Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation. Arthritis Res Ther (2013) 0.79

Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis. Expert Rev Vaccines (2015) 0.79

K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory Arthritis. Front Immunol (2016) 0.79

ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis. Rheumatol Int (2011) 0.78

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunol Cell Biol (2014) 0.78

Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis. Arthritis Res Ther (2015) 0.77

Trabecular bone loss in collagen antibody-induced arthritis. Arthritis Res Ther (2015) 0.77

The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function. Am J Clin Exp Immunol (2013) 0.77

Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis. Clin Exp Immunol (2017) 0.75

Human adipose-derived mesenchymal stem cells attenuate collagen antibody-induced autoimmune arthritis by inducing expression of FCGIIB receptors. BMC Musculoskelet Disord (2015) 0.75

Bifunctional Peptide Inhibitors Suppress Interleukin-6 Proliferation and Ameliorates Murine Collagen-Induced Arthritis. J Clin Cell Immunol (2014) 0.75

Effects of Calcium Gluconate, a Water Soluble Calcium Salt on the Collagen-Induced DBA/1J Mice Rheumatoid Arthritis. Biomol Ther (Seoul) (2013) 0.75

Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight (2017) 0.75

Borrelia burgdorferi infection induces lipid mediator production during Lyme arthritis. Biochimie (2017) 0.75

Articles cited by this

(truncated to the top 100)

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med (2004) 14.53

MGD: the Mouse Genome Database. Nucleic Acids Res (2003) 10.14

Autoimmunity to type II collagen an experimental model of arthritis. J Exp Med (1977) 10.09

Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science (2006) 8.13

Immunisation against heterologous type II collagen induces arthritis in mice. Nature (1980) 7.08

Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood (1994) 6.47

Organ-specific disease provoked by systemic autoimmunity. Cell (1996) 6.44

Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science (2002) 5.82

The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum (2006) 5.68

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity (1999) 5.38

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature (1985) 5.32

Arthritis critically dependent on innate immune system players. Immunity (2002) 5.31

Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science (1999) 4.97

The impact of glycosylation on the biological function and structure of human immunoglobulins. Annu Rev Immunol (2007) 4.96

Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol (2001) 4.39

FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity (2005) 4.22

Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum (1995) 3.83

Serum transfer of collagen-induced arthritis in mice. J Exp Med (1983) 3.74

Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis. J Clin Invest (2006) 3.51

Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease. Nat Immunol (2001) 3.39

Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nat Med (1995) 3.38

Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis. J Exp Med (2002) 2.98

Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra. Arthritis Rheum (1996) 2.92

Induction of arthritis with monoclonal antibodies to collagen. J Immunol (1992) 2.64

C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu Rev Immunol (1994) 2.57

Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest (2002) 2.56

Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum (1986) 2.56

Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes. Rheumatology (Oxford) (2001) 2.45

B cell-deficient mice do not develop type II collagen-induced arthritis (CIA). Clin Exp Immunol (1998) 2.27

Citrullination is an inflammation-dependent process. Ann Rheum Dis (2006) 2.25

C5a negatively regulates toll-like receptor 4-induced immune responses. Immunity (2005) 2.24

Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease. Proc Natl Acad Sci U S A (1995) 2.22

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity (2003) 2.20

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis. J Exp Med (2006) 2.15

Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol (2006) 2.12

Divergent roles for Fc receptors and complement in vivo. Annu Rev Immunol (1998) 2.12

C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease. J Clin Invest (2002) 2.11

Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med (2002) 2.09

Genetic influences on the end-stage effector phase of arthritis. J Exp Med (2001) 1.99

Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling. J Exp Med (2003) 1.99

The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis. J Clin Invest (2002) 1.98

Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis. Arthritis Rheum (1989) 1.95

Arthritogenic monoclonal antibodies from K/BxN mice. J Exp Med (2002) 1.94

Citrullination of synovial proteins in murine models of rheumatoid arthritis. Arthritis Rheum (2003) 1.88

Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself. Blood (1990) 1.86

Collagen-induced arthritis in mice: synergistic effect of E. coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen. Autoimmunity (1995) 1.85

A role for complement in antibody-mediated inflammation: C5-deficient DBA/1 mice are resistant to collagen-induced arthritis. J Immunol (2000) 1.82

Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. Am J Pathol (2003) 1.81

Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol (2004) 1.77

The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis. J Immunol (2002) 1.76

The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis. J Immunol (2002) 1.71

Plasma cell development in synovial germinal centers in patients with rheumatoid and reactive arthritis. J Immunol (1999) 1.71

The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis. J Immunol (2002) 1.70

Dynamic visualization of a joint-specific autoimmune response through positron emission tomography. Nat Immunol (2002) 1.68

Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. J Biol Chem (2004) 1.65

A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis. Eur J Immunol (2005) 1.65

Agalactosyl glycoforms of IgG autoantibodies are pathogenic. Proc Natl Acad Sci U S A (1994) 1.65

Citrullination: a small change for a protein with great consequences for rheumatoid arthritis. Arthritis Res (2000) 1.61

Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis. J Clin Invest (2000) 1.60

The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease. J Clin Invest (2004) 1.59

Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci U S A (2002) 1.55

Type II collagen-induced arthritis in mice. II. Passive transfer and suppression by intravenous injection of anti-type II collagen antibody or free native type II collagen. Arthritis Rheum (1984) 1.52

Antibodies to type II collagen in early rheumatoid arthritis. Correlation with disease progression. Arthritis Rheum (1996) 1.52

Arthritis in DBA/1 mice induced with passively transferred type II collagen immune serum. Immunohistopathology and serum levels of anti-type II collagen auto-antibodies. Scand J Immunol (1990) 1.51

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest (2006) 1.49

Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes. J Immunol (2004) 1.48

A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. J Immunol (1996) 1.47

Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum (1990) 1.46

Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA). Clin Exp Immunol (1997) 1.46

Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy. J Autoimmun (1991) 1.45

Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis Rheum (2003) 1.41

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis. J Exp Med (2002) 1.41

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2. Nat Genet (1999) 1.39

Development of C5a receptor antagonists. Differential loss of functional responses. J Immunol (1994) 1.39

Measurement of the chemotactic complement fragment C5a in rheumatoid synovial fluids by radioimmunoassay: role of C5a in the acute inflammatory phase. Ann Rheum Dis (1990) 1.38

Passive transfer of arthritis to mice by injection of human anti-type II collagen antibody. Mayo Clin Proc (1984) 1.37

Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis. Arthritis Rheum (2002) 1.36

NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production. J Exp Med (2005) 1.35

The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis. Arthritis Rheum (2000) 1.34

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB. Eur J Immunol (2003) 1.32

IL-10-deficient B10.Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with anti-type II collagen antibodies. J Immunol (2001) 1.32

Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury. J Immunol (1999) 1.31

Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen. Lab Invest (1986) 1.31

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis. Best Pract Res Clin Rheumatol (2004) 1.26

Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis. Eur J Immunol (2004) 1.26

Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR. J Immunol (2000) 1.24

Local production of complement proteins in rheumatoid arthritis synovium. Arthritis Rheum (2002) 1.24

Essential role of Fc gamma receptors in anti-type II collagen antibody-induced arthritis. J Immunol (2003) 1.22

Essential roles of Toll-like receptor-4 signaling in arthritis induced by type II collagen antibody and LPS. Int Immunol (2005) 1.21

Interleukin-4 can be a key positive regulator of inflammatory arthritis. Arthritis Rheum (2005) 1.18

Oncostatin M and leukemia inhibitory factor do not use the same functional receptor in mice. Blood (1997) 1.18

The role of CD40 ligand and tumor necrosis factor alpha signaling in the transgenic K/BxN mouse model of rheumatoid arthritis. Arthritis Rheum (2000) 1.17

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells. Arthritis Res Ther (2004) 1.15

CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. Int Immunol (2003) 1.14

p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. Am J Pathol (2006) 1.14

Passive transfer studies with type II collagen antibody in B10.D2/old and new line and C57Bl/6 normal and beige (Chediak-Higashi) strains: evidence of important roles for C5 and multiple inflammatory cell types in the development of erosive arthritis. Arthritis Rheum (1987) 1.14

Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. J Immunol Methods (2005) 1.13

Regulation of inflammatory responses by oncostatin M. J Immunol (1999) 1.13

Immune complex glomerulonephritis in C4- and C3-deficient mice. Kidney Int (1998) 1.13

The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis. Am J Pathol (2005) 1.13

Articles by these authors

(truncated to the top 100)

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37

Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01

Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat Genet (2002) 2.46

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc Natl Acad Sci U S A (2004) 2.38

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum (2010) 2.27

Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood (2002) 1.90

Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. Am J Pathol (2003) 1.81

The major T cell epitope on type II collagen is glycosylated in normal cartilage but modified by arthritis in both rats and humans. Eur J Immunol (2005) 1.74

Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species. J Clin Invest (2007) 1.71

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J Exp Med (2009) 1.68

IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis. J Immunol (2003) 1.68

T cell surface redox levels determine T cell reactivity and arthritis susceptibility. Proc Natl Acad Sci U S A (2006) 1.63

Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis. Proc Natl Acad Sci U S A (2002) 1.55

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile. Ann Rheum Dis (2012) 1.53

Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis. Eur J Immunol (2005) 1.51

NOX2 complex-derived ROS as immune regulators. Antioxid Redox Signal (2011) 1.50

The protective role of ROS in autoimmune disease. Trends Immunol (2009) 1.49

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species. Proc Natl Acad Sci U S A (2010) 1.47

Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis. Arthritis Rheum (2013) 1.46

Therapeutic cleavage of IgG: new avenues for treating inflammation. Trends Immunol (2008) 1.46

Rheumatoid arthritis and the complement system. Ann Med (2007) 1.42

Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse. Arthritis Rheum (2002) 1.39

In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med (2009) 1.35

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB. Eur J Immunol (2003) 1.32

Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis. Eur J Immunol (2007) 1.32

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet (2013) 1.30

Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis. Eur J Immunol (2004) 1.26

Basal metabolic rate and the evolution of the adaptive immune system. Proc Biol Sci (2002) 1.25

Animal models for arthritis: innovative tools for prevention and treatment. Ann Rheum Dis (2011) 1.20

Ethanol prevents development of destructive arthritis. Proc Natl Acad Sci U S A (2006) 1.18

Antibodies to citrullinated proteins: molecular interactions and arthritogenicity. Immunol Rev (2010) 1.17

Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. Arthritis Rheum (2007) 1.17

Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol (2006) 1.15

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells. Arthritis Res Ther (2004) 1.15

The role of collagen antibodies in mediating arthritis. Mod Rheumatol (2008) 1.13

Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. J Immunol Methods (2005) 1.13

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides. Arthritis Res Ther (2012) 1.13

A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock. Genome Res (2008) 1.13

The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis. Am J Pathol (2005) 1.13

Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections. J Immunol (2012) 1.13

Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice. Arthritis Rheum (2005) 1.10

A new arthritis therapy with oxidative burst inducers. PLoS Med (2006) 1.09

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity. Arthritis Res Ther (2007) 1.07

Comment on "The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease". Science (2003) 1.06

A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model. J Immunol (2008) 1.05

Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase. Arthritis Res Ther (2005) 1.03

IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis. Eur J Immunol (2002) 1.03

Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice. J Immunol (2007) 1.03

A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination. Eur J Immunol (2002) 1.02

Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies. Antioxid Redox Signal (2007) 1.02

Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen-induced arthritis. Eur J Immunol (2002) 1.00

Novel quantitative trait loci controlling development of experimental autoimmune encephalomyelitis and proportion of lymphocyte subpopulations. J Immunol (2003) 1.00

Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice. Arthritis Res Ther (2006) 0.99

The genetic control of rheumatoid factor production in a rat model of rheumatoid arthritis. Arthritis Rheum (2003) 0.99

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency. Arthritis Rheum (2012) 0.98

Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats. Arthritis Res Ther (2003) 0.98

Copy number variation of the gene NCF1 is associated with rheumatoid arthritis. Antioxid Redox Signal (2011) 0.98

Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress. Antioxid Redox Signal (2013) 0.98

Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. Arthritis Res Ther (2010) 0.98

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen. Arthritis Res Ther (2005) 0.96

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice. Cell Immunol (2005) 0.96

Genetic interactions in Eae2 control collagen-induced arthritis and the CD4+/CD8+ T cell ratio. J Immunol (2005) 0.96

Copy number variation in autoimmunity--importance hidden in complexity? Eur J Immunol (2012) 0.95

Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. J Immunol (2006) 0.95

Crystal structure of an arthritogenic anticollagen immune complex. Arthritis Rheum (2011) 0.95

Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils. Autoimmunity (2012) 0.94

Collagen antibody induced arthritis. Methods Mol Med (2007) 0.94

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature. Antioxid Redox Signal (2014) 0.94

Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation. J Leukoc Biol (2012) 0.94

Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis. Arthritis Rheum (2004) 0.94

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats. Ann Rheum Dis (2012) 0.93

Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells. J Pathol (2012) 0.93

Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. J Immunol (2013) 0.93

Identification of new citrulline-specific autoantibodies, which bind to human arthritic cartilage, by mass spectrometric analysis of citrullinated type II collagen. Arthritis Rheumatol (2014) 0.92

Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation. Arthritis Rheum (2008) 0.92

Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. J Immunol (2004) 0.91

Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis. Arthritis Rheum (2006) 0.91

The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis. J Immunol (2007) 0.91

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis. J Immunol (2006) 0.91

Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture. J Mol Recognit (2004) 0.91

The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model. Arthritis Rheum (2006) 0.90

Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model. J Immunol (2003) 0.90

Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis. Arthritis Rheum (2012) 0.90

The mtDNA nt7778 G/T polymorphism affects autoimmune diseases and reproductive performance in the mouse. Hum Mol Genet (2009) 0.90

Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms. J Exp Med (2014) 0.90

Three-dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles. Biotechnol Prog (2009) 0.89

C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells. Ann Rheum Dis (2012) 0.88

The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis. Arthritis Res Ther (2009) 0.88

CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species. Eur J Immunol (2010) 0.88

Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice. J Clin Invest (2010) 0.88

A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis. PLoS One (2010) 0.88

Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium. Arthritis Res Ther (2006) 0.87

Identification and isolation of dominant susceptibility loci for pristane-induced arthritis. J Immunol (2003) 0.87

Cartilage oligomeric matrix protein induction of chronic arthritis in mice. Arthritis Rheum (2008) 0.87

Identification of collagen-induced arthritis loci in aged multiparous female mice. Arthritis Res Ther (2006) 0.87

Arthritis induced with cartilage-specific antibodiesis IL-4-dependent. Eur J Immunol (2006) 0.87

Tolerance induction using lentiviral gene delivery delays onset and severity of collagen II arthritis. Mol Ther (2009) 0.86

Cartilage oligomeric matrix protein specific antibodies are pathogenic. Arthritis Res Ther (2012) 0.86

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice. Arthritis Res Ther (2014) 0.85

Monoclonal antibody production using a new supermacroporous cryogel bioreactor. Biotechnol Prog (2007) 0.85