Published in J Neurosci Res on March 01, 2007
Mild Hypothermia Suppresses Calcium-Sensing Receptor (CaSR) Induction Following Forebrain Ischemia While Increasing GABA-B Receptor 1 (GABA-B-R1) Expression. Transl Stroke Res (2011) 0.93
Hypothermia and pharmacological regimens that prevent overexpression and overactivity of the extracellular calcium-sensing receptor protect neurons against traumatic brain injury. J Neurotrauma (2013) 0.79
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet (2003) 13.33
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature (2005) 5.54
Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol (2003) 3.10
Acquired hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor. N Engl J Med (2004) 2.98
Physiology and pathophysiology of the calcium-sensing receptor in the kidney. Am J Physiol Renal Physiol (2009) 2.02
Activation of NAD(P)H:quinone oxidoreductase 1 prevents arterial restenosis by suppressing vascular smooth muscle cell proliferation. Circ Res (2009) 1.75
Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia. Mol Cell Biol (2003) 1.67
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol (2012) 1.59
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J Bone Miner Res (2007) 1.56
Activating autoantibodies against the calcium-sensing receptor detected in two patients with autoimmune polyendocrine syndrome type 1. J Clin Endocrinol Metab (2009) 1.55
Association of interleukin-4 and interleukin-1 receptor antagonist gene polymorphisms and risk of benign prostatic hyperplasia. Urology (2008) 1.54
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Hum Mol Genet (2010) 1.53
Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites. Hum Mol Genet (2012) 1.51
The calcium-sensing receptor in normal physiology and pathophysiology: a review. Crit Rev Clin Lab Sci (2005) 1.48
Lysosomal exocytosis is impaired in mucolipidosis type IV. Mol Genet Metab (2006) 1.45
Hypercalcaemic and hypocalcaemic conditions due to calcium-sensing receptor mutations. Best Pract Res Clin Rheumatol (2008) 1.44
Activating antibodies to the calcium-sensing receptor in two patients with autoimmune hypoparathyroidism. J Clin Endocrinol Metab (2004) 1.44
The empirical foundations of telemedicine interventions for chronic disease management. Telemed J E Health (2014) 1.34
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion. Am J Physiol Endocrinol Metab (2009) 1.32
pH Sensing by the calcium-sensing receptor. J Biol Chem (2004) 1.32
Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway. FEBS Lett (2002) 1.31
Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response. Biochemistry (2009) 1.27
Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Am J Physiol Gastrointest Liver Physiol (2006) 1.26
The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation. Biochem Pharmacol (2007) 1.23
The role of the calcium-sensing receptor in the development and progression of cancer. Endocr Rev (2009) 1.23
Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis. PLoS One (2012) 1.19
The calcium-sensing receptor regulates mammary gland parathyroid hormone-related protein production and calcium transport. J Clin Invest (2004) 1.17
Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV. Biochem Biophys Res Commun (2004) 1.16
The calcium-sensing receptor is involved in strontium ranelate-induced osteoclast apoptosis. New insights into the associated signaling pathways. J Biol Chem (2008) 1.14
Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor. J Biol Chem (2007) 1.13
Calcium-sensing receptor in the brain. Cell Calcium (2004) 1.12
Identification and functional characterization of novel calcium-sensing receptor mutations in familial hypocalciuric hypercalcemia and autosomal dominant hypocalcemia. J Clin Endocrinol Metab (2002) 1.11
Extracellular calcium sensing in rat aortic vascular smooth muscle cells. Biochem Biophys Res Commun (2006) 1.10
A syndrome of hypocalciuric hypercalcemia caused by autoantibodies directed at the calcium-sensing receptor. J Clin Endocrinol Metab (2003) 1.08
Functional expression of beta-chemokine receptors in osteoblasts: role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts. Endocrinology (2005) 1.08
Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function. J Biol Chem (2002) 1.08
Anti-tumor activity of a new series of benzoxazepine derivatives in breast cancer. Bioorg Med Chem Lett (2009) 1.08
Prevalence of calcium sensing receptor autoantibodies in patients with sporadic idiopathic hypoparathyroidism. Eur J Endocrinol (2004) 1.07
A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic bone: the role of aryl hydrocarbon receptor as a mediator of osteogenic action. J Bone Miner Res (2011) 1.07
Hypercalcemia and diabetes insipidus in a patient previously treated with lithium. Nat Clin Pract Nephrol (2007) 1.06
Mitogenic action of calcium-sensing receptor on rat calvarial osteoblasts. Endocrinology (2004) 1.04
Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond. J Physiol (2003) 1.02
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet (2013) 1.02
Role of calcium-sensing receptor in mineral ion metabolism and inherited disorders of calcium-sensing. Mol Genet Metab (2006) 1.00
Genetic polymorphism and pathogenesis of benign prostatic hyperplasia. BJU Int (2008) 1.00
Pituitary homeobox 1 activates the rat FSHbeta (rFSHbeta) gene through both direct and indirect interactions with the rFSHbeta gene promoter. Mol Endocrinol (2002) 0.99
The calcium-sensing receptor is a target of autoantibodies in patients with autoimmune polyendocrine syndrome type 1. J Clin Endocrinol Metab (2007) 0.98
Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene. J Biol Chem (2002) 0.98
L-amino acids regulate parathyroid hormone secretion. J Biol Chem (2004) 0.97
Calcium-sensing receptor in cancer: good cop or bad cop? Endocrine (2008) 0.96
Signaling through the extracellular calcium-sensing receptor (CaSR). Adv Exp Med Biol (2012) 0.95
Pilot case-control investigation of risk factors for hip fractures in the urban Indian population. BMC Musculoskelet Disord (2010) 0.95
PTHrP stimulated by the calcium-sensing receptor requires MAP kinase activation. Am J Physiol Endocrinol Metab (2002) 0.95
Kaempferol has osteogenic effect in ovariectomized adult Sprague-Dawley rats. Mol Cell Endocrinol (2008) 0.95
Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo. Am J Physiol Endocrinol Metab (2012) 0.95
AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity. J Lipid Res (2012) 0.94
Activin A augments GnRH-mediated transcriptional activation of the mouse GnRH receptor gene. Endocrinology (2002) 0.93
Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription. Mol Endocrinol (2004) 0.93
Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells. Endocrinology (2004) 0.93
A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA. J Biomol Screen (2006) 0.93
Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)benzoic acid analogues as BMP-2 stimulators. J Med Chem (2012) 0.93
Effects of Egb 761 on bone mineral density, bone microstructure, and osteoblast function: Possible roles of quercetin and kaempferol. Mol Cell Endocrinol (2009) 0.92
Editorial: mutant extracellular calcium-sensing receptors and severity of disease. J Clin Endocrinol Metab (2005) 0.92
The emerging role of pituitary tumor transforming gene in tumorigenesis. Clin Med Res (2006) 0.92
Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling. J Cell Biochem (2009) 0.91
Pituitary homeobox 1 (Pitx1) stimulates rat LHbeta gene expression via two functional DNA-regulatory regions. J Mol Endocrinol (2005) 0.90
Telestroke: a multi-site, emergency-based telemedicine service in Ontario. J Telemed Telecare (2006) 0.90
Co-expression of Arabidopsis transcription factor, AtMYB12, and soybean isoflavone synthase, GmIFS1, genes in tobacco leads to enhanced biosynthesis of isoflavones and flavonols resulting in osteoprotective activity. Plant Biotechnol J (2013) 0.90
Investigational anabolic therapies for osteoporosis. Expert Opin Investig Drugs (2010) 0.90
Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor β-mediated osteogenic action of medicarpin. J Nutr Biochem (2011) 0.90
High calcium activates the EGF receptor potentially through the calcium-sensing receptor in Leydig cancer cells. Growth Factors (2005) 0.89
Calmodulin regulates Ca2+-sensing receptor-mediated Ca2+ signaling and its cell surface expression. J Biol Chem (2010) 0.89
Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice. Mol Cell Endocrinol (2010) 0.88
The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice. Am J Physiol Endocrinol Metab (2012) 0.87
Differential effects of formononetin and cladrin on osteoblast function, peak bone mass achievement and bioavailability in rats. J Nutr Biochem (2010) 0.87
Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells. Biochem Pharmacol (2006) 0.87
Abnormal parathyroid cell proliferation precedes biochemical abnormalities in a mouse model of primary hyperparathyroidism. Mol Endocrinol (2005) 0.87
Role of phytochemicals in the prevention of menopausal bone loss: evidence from in vitro and in vivo, human interventional and pharma-cokinetic studies. Curr Med Chem (2009) 0.87
Apical entry channels in calcium-transporting epithelia. News Physiol Sci (2003) 0.87
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells. Brain Res Mol Brain Res (2002) 0.87
Breast cancer risk associated with polymorphisms of IL-1RN and IL-4 gene in Indian women. Oncol Res (2009) 0.86
Attenuation of osteoclastogenesis and osteoclast function by apigenin. Biochem Pharmacol (2006) 0.85
Calcium receptor stimulates chemotaxis and secretion of MCP-1 in GnRH neurons in vitro: potential impact on reduced GnRH neuron population in CaR-null mice. Am J Physiol Endocrinol Metab (2006) 0.85
Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α. Mol Endocrinol (2011) 0.85
Enhanced immunoprotective effects by anti-IL-17 antibody translates to improved skeletal parameters under estrogen deficiency compared with anti-RANKL and anti-TNF-α antibodies. J Bone Miner Res (2014) 0.85