ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

PubWeight™: 1.46‹?› | Rank: Top 5%

🔗 View Article (PMID 17290285)

Published in Cell Death Differ on February 09, 2007

Authors

M Schulte1, K Reiss, M Lettau, T Maretzky, A Ludwig, D Hartmann, B de Strooper, O Janssen, P Saftig

Author Affiliations

1: Biochemical Institute, Christian-Albrecht-University, Kiel, Germany.

Articles citing this

Matrix metalloproteinases: regulators of the tumor microenvironment. Cell (2010) 12.90

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature (2009) 2.54

CD95, BIM and T cell homeostasis. Nat Rev Immunol (2009) 1.73

ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. Circ Res (2008) 1.66

Fas death receptor signalling: roles of Bid and XIAP. Cell Death Differ (2011) 1.63

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. Biochem J (2009) 1.49

Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 1.48

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. J Exp Med (2010) 1.47

ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase. J Biol Chem (2009) 1.33

Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. J Clin Invest (2009) 1.33

TNF superfamily: a growing saga of kidney injury modulators. Mediators Inflamm (2010) 1.20

Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein. Blood (2010) 1.14

Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. J Biol Chem (2010) 1.13

ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis. J Immunol (2010) 1.02

Enzyme-instructed self-assembly: a multistep process for potential cancer therapy. Bioconjug Chem (2015) 0.97

The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region. J Clin Invest (2011) 0.96

Pericellular proteolysis in cancer. Genes Dev (2014) 0.92

Targeting immune privilege to prevent pathogenic neovascularization. Invest Ophthalmol Vis Sci (2010) 0.92

Posttranslational regulation of Fas ligand function. Cell Commun Signal (2008) 0.90

Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses. Results Probl Cell Differ (2009) 0.89

Dual role of immune cells in the testis: Protective or pathogenic for germ cells? Spermatogenesis (2013) 0.88

The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity. Mol Immunol (2011) 0.88

The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis. Spermatogenesis (2011) 0.88

Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells. PLoS One (2013) 0.87

ERα signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis. J Bone Miner Res (2013) 0.87

Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus. J Immunol (2013) 0.85

Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells. J Am Chem Soc (2016) 0.85

Palmitoylation of human FasL modulates its cell death-inducing function. Cell Death Dis (2010) 0.82

Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing. Immunology (2014) 0.81

Fell-Muir Lecture: Metalloproteinases: from demolition squad to master regulators. Int J Exp Pathol (2010) 0.80

A critical role for FcgammaRIIB in up-regulation of Fas ligand induced by a microbial polysaccharide. Clin Exp Immunol (2011) 0.80

Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10). PLoS One (2014) 0.78

Increased synapse formation obtained by T cell epitopes containing a CxxC motif in flanking residues convert CD4+ T cells into cytolytic effectors. PLoS One (2012) 0.78

Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells. Cancer Gene Ther (2008) 0.76

Fas/FasL, Bcl2 and Caspase-8 gene polymorphisms in Chinese patients with rheumatoid arthritis. Rheumatol Int (2016) 0.76

Autocrine IFNγ controls the regulatory function of lymphoproliferative double negative T cells. PLoS One (2012) 0.76

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. BMC Immunol (2009) 0.76

The CD95 signaling pathway: To not die and fly. Commun Integr Biol (2012) 0.76

Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase. Oncotarget (2017) 0.75

The Janus Face of Death Receptor Signaling during Tumor Immunoediting. Front Immunol (2016) 0.75

CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases. Front Immunol (2017) 0.75

Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy. Nat Rev Cancer (2017) 0.75

Articles by these authors

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature (1999) 10.36

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature (1998) 7.43

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature (2000) 6.34

mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors. EMBO J (2000) 4.06

Cloud-radiative forcing and climate: results from the Earth radiation budget experiment. Science (1989) 3.58

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest (1996) 3.42

A cytolysin encoded by Salmonella is required for survival within macrophages. Proc Natl Acad Sci U S A (1994) 2.87

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency. Proc Natl Acad Sci U S A (1999) 2.82

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc Natl Acad Sci U S A (1998) 2.75

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature (1998) 2.56

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues. Eur J Biochem (2001) 2.47

Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A (1999) 2.46

The randomized shortened dental arch study: tooth loss. J Dent Res (2010) 2.35

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons. J Neurosci (2000) 2.21

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling. FASEB J (2000) 2.09

[Phenprocoumon-induced necrotizing hepatitis]. Dtsch Med Wochenschr (2001) 2.08

Single dose kinetics of mefloquine in man. Plasma levels of the unchanged drug and of one of its metabolites. Chemotherapy (1982) 2.06

Mutations affecting activity and transport of haemolysin in Escherichia coli. Mol Gen Genet (1987) 2.01

Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res (1996) 1.95

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch. J Biol Chem (1999) 1.82

Differential distribution of four hyperpolarization-activated cation channels in mouse brain. Biol Chem (1999) 1.82

Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J Immunol (1993) 1.81

The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem (2001) 1.76

Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest (1998) 1.73

The primary response of human gamma/delta + T cells to Mycobacterium tuberculosis is restricted to V gamma 9-bearing cells. J Exp Med (1991) 1.69

Contrast-enhanced color Doppler sonography for evaluation of enlarged cervical lymph nodes in head and neck tumors. AJR Am J Roentgenol (2000) 1.68

Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation. Circulation (2005) 1.66

On the requirements of ascorbic acid in man: steady-state turnover and body pool in smokers. Am J Clin Nutr (1981) 1.66

Early embryonic death of mice deficient in gamma-adaptin. J Biol Chem (1999) 1.64

Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells. Proc Natl Acad Sci U S A (1993) 1.62

Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60

A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res (1998) 1.60

Structure and function of cyclic nucleotide-gated channels. Rev Physiol Biochem Pharmacol (1999) 1.59

Cathepsin D targeted by acid sphingomyelinase-derived ceramide. EMBO J (1999) 1.56

Proteases involved in MHC class II antigen presentation. Immunol Rev (1999) 1.54

Control of the antitumoral activity of human macrophages produced in large amounts in view of adoptive transfer. Eur J Cancer Clin Oncol (1988) 1.52

Vitamin A teratogenicity and risk assessment in the macaque retinoid model. Reprod Toxicol (2000) 1.50

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol (1996) 1.49

Insulin-like growth factor-1 and myocyte growth: the danger of a dogma. Part I. Postnatal myocardial development: normal growth. Cardiovasc Res (1996) 1.49

[S3-guidelines--sedation in gastrointestinal endoscopy]. Z Gastroenterol (2008) 1.47

Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. J Biol Chem (1994) 1.47

The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein. J Cell Biol (2001) 1.46

Differential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampus. Neuroscience (2001) 1.44

Phenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophy. Proc Natl Acad Sci U S A (1996) 1.44

Structural and functional characterization of human NAD kinase. Biochem Biophys Res Commun (2001) 1.42

Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41

Alternatively spliced IS6 segments of the alpha 1C gene determine the tissue-specific dihydropyridine sensitivity of cardiac and vascular smooth muscle L-type Ca2+ channels. Circ Res (1997) 1.41

Normal lysosomal morphology and function in LAMP-1-deficient mice. J Biol Chem (1999) 1.41

Insulin-like growth factor-1 and myocyte growth: the danger of a dogma part II. Induced myocardial growth: pathologic hypertrophy. Cardiovasc Res (1996) 1.41

The bone lining cell: its role in cleaning Howship's lacunae and initiating bone formation. J Bone Miner Res (2002) 1.41

[In-hospital mortality of acute hemorrhage of esophageal/fundus varices: an analysis of blood glucose level and other risk factors in 99 consecutive patients]. Dtsch Med Wochenschr (2007) 1.39

Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7  TeV. Phys Rev Lett (2011) 1.39

Characterization of the antibody response specific for the human endogenous retrovirus HTDV/HERV-K. J Virol (1997) 1.37

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. J Neurosci (1996) 1.37

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase. Mol Cell Biol (1993) 1.34

Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32

Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases. Immunol Today (1994) 1.32

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins. EMBO J (1993) 1.31

The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation. J Leukoc Biol (2000) 1.31

Long-term follow-up after first acute episode of sigmoid diverticulitis: is surgery mandatory?: a prospective study of 118 patients. Dis Colon Rectum (2002) 1.30

Effect of micro- and macroporosity of bone substitutes on their mechanical properties and cellular response. J Mater Sci Mater Med (2003) 1.30

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation. Oncogene (2001) 1.29

Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer. Neuroscience (2002) 1.26

Generation of soluble NKG2D ligands: proteolytic cleavage, exosome secretion and functional implications. Scand J Immunol (2013) 1.24

Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene (1998) 1.22

Immunofluorescent localization of collagen types I and III, and of fibronectin during feather morphogenesis in the chick embryo. Dev Biol (1982) 1.22

Platelet-derived CXC chemokines: old players in new games. Immunol Rev (2000) 1.21

Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans. Bone (1997) 1.21

Molecular cloning and expression of the Modulatory subunit of the cyclic nucleotide-gated cation channel. J Biol Chem (1996) 1.21

Bioavailability from various galenic formulations of flunitrazepam. Arzneimittelforschung (1977) 1.19

Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19

Bone density, strength, and formation in adult cathepsin K (-/-) mice. Bone (2008) 1.19

Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice. Development (2001) 1.19

Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res (1994) 1.17

Osteonecrosis after chemotherapy. Lancet (1978) 1.17

A note on name, viability and urease tests of Campylobacter pylori. Eur J Clin Microbiol (1987) 1.16

Activation and activation-driven death of human gamma/delta T cells. Immunol Rev (1991) 1.16

Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. Brain (2005) 1.15

src-related protein tyrosine kinases and their surface receptors. Biochim Biophys Acta (1993) 1.15

The gene slyA of Salmonella typhimurium is required for destruction of M cells and intracellular survival but not for invasion or colonization of the murine small intestine. Infect Immun (1996) 1.14

Steady-state turnover and body pool of ascorbic acid in man. Am J Clin Nutr (1979) 1.13

Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13

Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant. J Exp Med (1998) 1.13

The role of the penetrating wound in the development of sympathetic ophthalmia experimental observations. Arch Ophthalmol (1983) 1.11

Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas. Oncogene (2001) 1.11

Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice. J Neurosci (2001) 1.10

Biocompatible stabilizers in the preparation of PLGA nanoparticles: a factorial design study. Int J Pharm (2002) 1.10

T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T). J Exp Med (1993) 1.10

Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion. Oncogene (1999) 1.10

Targeted disruption of the arylsulfatase B gene results in mice resembling the phenotype of mucopolysaccharidosis VI. Proc Natl Acad Sci U S A (1996) 1.10

Chitinase in roots of mycorrhizal Allium porrum: regulation and localization. Planta (1989) 1.09

Implication of APP secretases in notch signaling. J Mol Neurosci (2001) 1.09