Epithelia: lymphocyte interactions in the gut.

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Published in Immunol Rev on February 01, 2007

Authors

Stephanie Dahan1, Franziska Roth-Walter, Paul Arnaboldi, Shradha Agarwal, Lloyd Mayer

Author Affiliations

1: Immunobiology Center, Mount Sinai School of Medicine, New York, NY 10029, USA.

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature (2001) 25.15

Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 22.57

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Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell (1993) 11.95

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Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol (2000) 6.57

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Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development (1994) 3.86

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest (2005) 3.83

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Immunoelectron microscopic localization of HLA-DR antigen in control small intestine and colon and in inflammatory bowel disease. Dig Dis Sci (1986) 1.31

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Sequential and rapid activation of select caspases during apoptosis of normal intestinal epithelial cells. Am J Physiol (1998) 1.10

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