Published in PLoS One on February 21, 2007
Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Expert Rev Mol Med (2009) 2.77
KIR/HLA interactions and pathogen immunity. J Biomed Biotechnol (2011) 1.26
The host genetic diversity in malaria infection. J Trop Med (2012) 1.08
Variation in the ICAM1 gene is not associated with severe malaria phenotypes. Genes Immun (2008) 1.07
Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda. Malar J (2010) 0.97
Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection. Br J Haematol (2012) 0.89
Natural killer cells in immunodefense against infective agents. Expert Rev Anti Infect Ther (2008) 0.86
Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts. Malar J (2008) 0.82
Plasmodium falciparum-infected erythrocytes and IL-12/IL-18 induce diverse transcriptomes in human NK cells: IFN-α/β pathway versus TREM signaling. PLoS One (2011) 0.80
Differential association of gene content polymorphisms of killer cell immunoglobulin-like receptors with placental malaria in HIV- and HIV+ mothers. PLoS One (2012) 0.79
Limited response of NK92 cells to Plasmodium falciparum-infected erythrocytes. Malar J (2011) 0.79
Endothelial cells potentiate interferon-γ production in a novel tripartite culture model of human cerebral malaria. PLoS One (2013) 0.78
Plasmodium falciparum-Infected Erythrocyte Knob Density Is Linked to the PfEMP1 Variant Expressed. MBio (2015) 0.78
NK Cells: Uncertain Allies against Malaria. Front Immunol (2017) 0.75
Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science (1996) 10.03
Inferences, questions and possibilities in Toll-like receptor signalling. Nature (2004) 7.57
Targeting malaria virulence and remodeling proteins to the host erythrocyte. Science (2004) 7.01
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med (2006) 6.54
Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell (1988) 5.75
CD36 is a sensor of diacylglycerides. Nature (2005) 5.20
The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell (1990) 4.83
Natural killer cells and pregnancy. Nat Rev Immunol (2002) 4.21
Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell (1991) 4.15
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum. Nature (2000) 3.90
Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential. J Exp Med (2003) 3.46
Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J (2003) 3.06
Developmental selection of var gene expression in Plasmodium falciparum. Nature (1998) 2.96
A family affair: var genes, PfEMP1 binding, and malaria disease. Curr Opin Microbiol (2006) 2.93
Molecular basis of sequestration in severe and uncomplicated Plasmodium falciparum malaria: differential adhesion of infected erythrocytes to CD36 and ICAM-1. J Infect Dis (1991) 2.87
A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A. EMBO Rep (2005) 2.53
Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate. Curr Opin Struct Biol (2003) 2.48
The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site. Cell (1992) 2.29
Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance. Blood (2000) 2.26
Mutually exclusive expression of virulence genes by malaria parasites is regulated independently of antigen production. PLoS Pathog (2006) 2.18
Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol (2002) 2.12
Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades. Free Radic Biol Med (2000) 2.08
A role for CD36 in the regulation of dendritic cell function. Proc Natl Acad Sci U S A (2001) 1.93
Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomes. J Immunol (2006) 1.62
Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes. J Immunol (2003) 1.52
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci U S A (2005) 1.50
The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytes. Blood (2006) 1.46
The role of ICAM-1 in Plasmodium falciparum cytoadherence. Eur J Cell Biol (2005) 1.45
Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog (2006) 1.40
Mechanisms contributing to the activity of integrins on leukocytes. Immunol Rev (2002) 1.39
var genes, PfEMP1 and the human host. Mol Biochem Parasitol (2004) 1.34
Early interactions between blood-stage plasmodium parasites and the immune system. Curr Top Microbiol Immunol (2005) 1.26
Heterogeneous human NK cell responses to Plasmodium falciparum-infected erythrocytes. J Immunol (2005) 1.20
A functional analysis of a natural variant of intercellular adhesion molecule-1 (ICAM-1Kilifi). Hum Mol Genet (2000) 1.19
Biological and biochemical characteristics of cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate. Infect Immun (1998) 1.18
The structural motif in chondroitin sulfate for adhesion of Plasmodium falciparum-infected erythrocytes comprises disaccharide units of 4-O-sulfated and non-sulfated N-acetylgalactosamine linked to glucuronic acid. J Biol Chem (2002) 1.15
Innate sensors of microbial infection. J Clin Immunol (2005) 1.05
Interaction of ICAM-1 with beta 2-integrin CD11c/CD18: characterization of a peptide ligand that mimics a putative binding site on domain D4 of ICAM-1. Eur J Immunol (2005) 0.94
CD36 deficiency is frequent and can cause platelet immunization in Africans. Transfusion (1999) 0.90
Functions of natural killer cells. Nat Immunol (2008) 9.88
Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68
Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94
Human NK cell education by inhibitory receptors for MHC class I. Immunity (2006) 6.73
TLR3 deficiency in patients with herpes simplex encephalitis. Science (2007) 5.86
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol (2008) 4.78
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (2013) 4.60
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum. Cell (2005) 4.33
Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites. Cell (2005) 4.26
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol (2008) 3.93
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc Natl Acad Sci U S A (2007) 3.60
Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol (2012) 3.43
Maturation of mouse NK cells is a 4-stage developmental program. Blood (2009) 3.31
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med (2009) 3.17
Natural-killer cells and dendritic cells: "l'union fait la force". Blood (2005) 3.10
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 3.03
Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites. Cell Host Microbe (2009) 2.95
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med (2005) 2.93
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol (2002) 2.87
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med (2007) 2.85
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood (2009) 2.75
5' flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasites. Mol Microbiol (2007) 2.72
The trafficking of natural killer cells. Immunol Rev (2007) 2.62
Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc Natl Acad Sci U S A (2005) 2.55
A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A. EMBO Rep (2005) 2.53
LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation. Exp Cell Res (2006) 2.48
Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites. J Infect Dis (2005) 2.24
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells. Blood (2008) 2.24
Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz. Nature (2006) 2.19
NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol (2009) 2.12
Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol (2007) 2.11
Cutting edge: Priming of NK cells by IL-18. J Immunol (2008) 2.08
Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study. Blood (2008) 2.07
Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future. Immunol Rev (2008) 2.05
Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc Natl Acad Sci U S A (2011) 2.01
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol (2007) 2.00
Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science (2012) 1.98
Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses. J Immunol (2011) 1.97
Natural killer cells promote early CD8 T cell responses against cytomegalovirus. PLoS Pathog (2007) 1.93
Treatment of severe immune thrombocytopenia associated with systemic lupus erythematosus: 59 cases. J Rheumatol (2002) 1.91
Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations. Proc Natl Acad Sci U S A (2005) 1.85
Delayed hemolytic transfusion reaction in sickle cell disease patients: evidence of an emerging syndrome with suicidal red blood cell death. Transfusion (2009) 1.78
Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells. EMBO J (2011) 1.74
Using LUMA: a Luminometric-based assay for global DNA-methylation. Epigenetics (2006) 1.74
Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med (2007) 1.73
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA. Proc Natl Acad Sci U S A (2010) 1.73
Autoimmune thrombocytopenic Purpura and Helicobacter pylori infection. Arch Intern Med (2002) 1.72
Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum. PLoS Biol (2009) 1.72
The speed of change: towards a discontinuity theory of immunity? Nat Rev Immunol (2013) 1.72
Romiplostim safety and efficacy for immune thrombocytopenia in clinical practice: 2-year results of 72 adults in a romiplostim compassionate-use program. Blood (2011) 1.71
A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes. EMBO J (2002) 1.69
Hepatitis E transmission by transfusion of Intercept blood system-treated plasma. Blood (2014) 1.68
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses. Blood (2007) 1.66
Natural killer cells: from CD3(-)NKp46(+) to post-genomics meta-analyses. Curr Opin Immunol (2007) 1.65
The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. Blood (2009) 1.59
Platelets reorient Plasmodium falciparum-infected erythrocyte cytoadhesion to activated endothelial cells. J Infect Dis (2004) 1.57
A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation. EMBO J (2002) 1.56
Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood (2008) 1.56
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies. Blood (2013) 1.55
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med (2012) 1.52
Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. J Immunol (2012) 1.51
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci U S A (2005) 1.50
Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells. Blood (2005) 1.50
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors. Eur J Immunol (2004) 1.48
A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell. Mol Microbiol (2007) 1.48
Plasmodium falciparum heterochromatin protein 1 binds to tri-methylated histone 3 lysine 9 and is linked to mutually exclusive expression of var genes. Nucleic Acids Res (2009) 1.46
Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularisation. Development (2006) 1.46
Interferon-γ production by natural killer cells and cytomegalovirus in critically ill patients. Crit Care Med (2012) 1.43
Multiplicity and plasticity of natural killer cell signaling pathways. Blood (2005) 1.40
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum. Nature (2013) 1.40
Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med (2012) 1.39
Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells. Proc Natl Acad Sci U S A (2010) 1.38
Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. J Clin Invest (2012) 1.35
Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infection. J Exp Med (2002) 1.33
Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites. Malar J (2008) 1.32
Osteoblastic differentiation of human mesenchymal stem cells with platelet lysate. Biomaterials (2009) 1.32
Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies. Microbes Infect (2006) 1.31
Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci Signal (2011) 1.30