Published in J Immunol on March 15, 2007
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity (2007) 12.98
Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination. Immunity (2008) 2.04
Multispectral imaging of hematopoietic cells: where flow meets morphology. J Immunol Methods (2008) 1.74
A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity. Immunity (2011) 1.58
Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus. Immunity (2013) 1.33
T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain. Mol Cell Biol (2007) 1.28
Transcriptional control of invariant NKT cell development. Immunol Rev (2010) 1.24
Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PLoS Biol (2013) 1.08
Transcriptional control of rapid recall by memory CD4 T cells. J Immunol (2011) 0.98
IL-36γ/IL-1F9, an innate T-bet target in myeloid cells. J Biol Chem (2012) 0.92
Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions. Cytokine Growth Factor Rev (2013) 0.88
Transcriptional regulatory networks for CD4 T cell differentiation. Curr Top Microbiol Immunol (2014) 0.86
TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells. J Exp Med (2013) 0.86
Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4. J Immunol (2013) 0.85
N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation. J Exp Med (2013) 0.85
A continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells. Immunology (2009) 0.83
Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans. J Immunol (2012) 0.82
Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell. J Biol Chem (2010) 0.82
Transfusion of nonobese diabetic mice with allogeneic newborn blood ameliorates autoimmune diabetes and modifies the expression of selected immune response genes. J Immunol (2010) 0.81
More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases. Immunotherapy (2011) 0.78
Correlation Network Analysis Reveals Relationships between MicroRNAs, Transcription Factor T-bet, and Deregulated Cytokine/Chemokine-Receptor Network in Pulmonary Sarcoidosis. Mediators Inflamm (2015) 0.77
T-bet-dependent regulation of CD8+ T-cell expansion during experimental Trypanosoma cruzi infection. Immunology (2009) 0.77
Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27. Front Immunol (2017) 0.76
Human memory, but not naive, CD4+ T cells expressing transcription factor T-bet might drive rapid cytokine production. J Biol Chem (2014) 0.76
Antitumor Responses of Invariant Natural Killer T Cells. J Immunol Res (2015) 0.75
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity (2007) 12.98
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol (2005) 8.27
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science (2008) 6.52
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity (2004) 6.43
The unconventional lifestyle of NKT cells. Nat Rev Immunol (2002) 4.79
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med (2003) 4.68
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol (2010) 4.32
Structural insights into histone demethylation by JMJD2 family members. Cell (2006) 3.37
CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr Opin Immunol (2008) 3.37
Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol (2007) 3.19
Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells. J Exp Med (2002) 3.06
Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol (2008) 2.79
Homeostasis of V alpha 14i NKT cells. Nat Immunol (2002) 2.67
Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity (2009) 2.61
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature (2009) 2.43
Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat Immunol (2011) 2.42
Recognition of CD1d-restricted antigens by natural killer T cells. Nat Rev Immunol (2012) 2.32
Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. Proc Natl Acad Sci U S A (2003) 2.28
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity (2011) 2.11
Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology (2003) 2.00
A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity (2011) 1.94
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J (2009) 1.88
T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity (2009) 1.85
Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. Immunity (2002) 1.83
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol (2004) 1.82
T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood (2005) 1.80
CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med (2003) 1.63
A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. J Exp Med (2008) 1.60
Developmental program of mouse Valpha14i NKT cells. Curr Opin Immunol (2005) 1.58
Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter. Mol Cell Biol (2002) 1.44
Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat Immunol (2012) 1.44
The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer. Epigenetics (2009) 1.43
Sensitivity measurement and compensation in spectral imaging. Cytometry A (2006) 1.41
Interaction of JMJD6 with single-stranded RNA. Proc Natl Acad Sci U S A (2010) 1.37
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proc Natl Acad Sci U S A (2012) 1.37
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol (2010) 1.34
Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP). Nucleic Acids Res (2003) 1.34
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5. Proc Natl Acad Sci U S A (2009) 1.34
Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol Cell Biol (2003) 1.33
Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage. Proc Natl Acad Sci U S A (2009) 1.30
From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment. Curr Opin Immunol (2010) 1.25
Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells. Eur J Immunol (2008) 1.24
Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro. J Immunol (2010) 1.24
Receptor cross-linking on human plasmacytoid dendritic cells leads to the regulation of IFN-alpha production. J Immunol (2006) 1.24
Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes. Nat Immunol (2006) 1.23
Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol (2012) 1.22
Quantitative analysis of protein co-localization on B cells opsonized with rituximab and complement using the ImageStream multispectral imaging flow cytometer. J Immunol Methods (2006) 1.17
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly. Dev Cell (2012) 1.16
T cells and their eons-old obsession with MHC. Immunol Rev (2012) 1.13
Expression of a non-DNA-binding Ikaros isoform exclusively in B cells leads to autoimmunity but not leukemogenesis. Eur J Immunol (2007) 1.12
Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells. J Immunol (2007) 1.11
IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression. J Immunol (2007) 1.10
Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression. Proc Natl Acad Sci U S A (2010) 1.09
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem (2009) 1.09
Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes (2012) 1.09
Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. J Immunol (2007) 1.08
Early B cell factor: Regulator of B lineage specification and commitment. Semin Immunol (2008) 1.07
Evolutionarily conserved features contribute to αβ T cell receptor specificity. Immunity (2011) 1.06
CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. J Immunol (2013) 1.05
A critical role of costimulation during intrathymic development of invariant NK T cells. J Immunol (2008) 1.05
A dose-dependent role for EBF1 in repressing non-B-cell-specific genes. Eur J Immunol (2011) 1.04
Cutting edge: FADD is not required for antigen receptor-mediated NF-kappaB activation. J Immunol (2005) 1.03
MAIT cell recognition of MR1 on bacterially infected and uninfected cells. PLoS One (2013) 1.02
Functional analysis of -571 IL-10 promoter polymorphism reveals a repressor element controlled by sp1. J Immunol (2004) 1.01
An introduction to mass cytometry: fundamentals and applications. Cancer Immunol Immunother (2013) 0.99
Roles of EBF and Pax-5 in B lineage commitment and development. Semin Immunol (2002) 0.98
Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc Natl Acad Sci U S A (2011) 0.98
The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes. Mol Immunol (2008) 0.97
Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity. Vaccine (2009) 0.96
Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells. J Invest Dermatol (2013) 0.95
ImageStream cytometry extends the analysis of phagocytosis and oxidative burst. Scand J Clin Lab Invest (2011) 0.95
Natural killer T cells: know thyself. Proc Natl Acad Sci U S A (2007) 0.94
Numbers matter: quantitative and dynamic analysis of the formation of an immunological synapse using imaging flow cytometry. J Immunol Methods (2009) 0.94
Image-based study of interferongenic interactions between plasmacytoid dendritic cells and HSV-infected monocyte-derived dendritic cells. Immunol Invest (2007) 0.93
ImageStream promyelocytic leukemia protein immunolocalization: in search of promyelocytic leukemia cells. Cytometry A (2012) 0.92
CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol (2011) 0.91
A closer look at TCR germline recognition. Immunity (2012) 0.91
MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes. Mol Cell Biol (2012) 0.90
Human ovarian tumor ascites fluids rapidly and reversibly inhibit T cell receptor-induced NF-κB and NFAT signaling in tumor-associated T cells. Cancer Immun (2013) 0.89
Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A (2013) 0.88
The making of NKT cells. Nat Immunol (2008) 0.87
Immune modulation with sulfasalazine attenuates immunopathogenesis but enhances macrophage-mediated fungal clearance during Pneumocystis pneumonia. PLoS Pathog (2010) 0.87
Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function. Immunol Rev (2014) 0.85
iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma. PLoS One (2012) 0.85
Flow cytometric analysis of microparticles. Methods Mol Biol (2011) 0.84
Visualization and quantification of cytotoxicity mediated by antibodies using imaging flow cytometry. J Immunol Methods (2011) 0.84
T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes. Eur J Immunol (2012) 0.84
Image cytometry-based detection of aneuploidy by fluorescence in situ hybridization in suspension. Cytometry A (2012) 0.84
Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5. J Mol Biol (2009) 0.83
Colitis-related public T cells are selected in the colonic lamina propria of IL-10-deficient mice. Clin Immunol (2002) 0.82
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J (2009) 0.82
Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production. J Immunol (2010) 0.82
Group 1 CD1-restricted T cells take center stage. Eur J Immunol (2011) 0.82
Beryllium-induced TNF-alpha production is transcription-dependent in chronic beryllium disease. Am J Respir Cell Mol Biol (2006) 0.81
High throughput, parallel imaging and biomarker quantification of human spermatozoa by ImageStream flow cytometry. Syst Biol Reprod Med (2009) 0.81
Mucosal associated invariant T cells: don't forget your vitamins. Cell Res (2012) 0.79
Does the developmental status of Valpha14i NKT cells play a role in disease? Int Rev Immunol (2007) 0.78
Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. Eur J Immunol (2012) 0.78