Published in J Immunol on March 15, 2007
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 1.74
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response. Genome Biol (2012) 1.62
Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families. BMC Biol (2010) 1.05
Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion molecule isoforms. Infect Immun (2007) 1.04
Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells. J Transl Med (2008) 1.01
Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae. Infect Immun (2011) 0.98
The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2. Cell Commun Signal (2011) 0.95
The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria. PLoS One (2012) 0.92
Global analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory program. PLoS Pathog (2014) 0.88
Phosphatidylinositol 3'-kinase activity is critical for initiating the oxidative burst and bacterial destruction during CEACAM3-mediated phagocytosis. J Biol Chem (2011) 0.88
Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling. BMC Biol (2009) 0.88
Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1. PLoS One (2011) 0.84
Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens. PLoS One (2012) 0.79
Rho GTPases as pathogen targets: Focus on curable sexually transmitted infections. Small GTPases (2015) 0.78
SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. Cell Rep (2016) 0.78
Grb14 is a negative regulator of CEACAM3-mediated phagocytosis of pathogenic bacteria. J Biol Chem (2012) 0.77
The granulocyte orphan receptor CEACAM4 is able to trigger phagocytosis of bacteria. J Leukoc Biol (2015) 0.77
Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections. Infect Immun (2013) 0.76
Understanding the molecular aspects of oriental obesity pattern differentiation using DNA microarray. J Transl Med (2015) 0.75
Biochemical and Functional Insights into the Integrated Regulation of Innate Immune Cell Responses by Teleost Leukocyte Immune-Type Receptors. Biology (Basel) (2016) 0.75
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem (2002) 3.47
Public knowledge of benefits of breast and prostate cancer screening in Europe. J Natl Cancer Inst (2009) 3.45
Differential regulation of cell motility and invasion by FAK. J Cell Biol (2003) 3.15
Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice. Gastroenterology (2010) 2.35
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem (2004) 2.29
CEACAMs: their role in physiology and pathophysiology. Curr Opin Cell Biol (2006) 2.13
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell (2008) 2.12
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe (2009) 2.01
Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery. Cancer Cell (2004) 2.00
Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. EMBO J (2004) 1.73
Identification of a novel plasmin(ogen)-binding motif in surface displayed alpha-enolase of Streptococcus pneumoniae. Mol Microbiol (2003) 1.72
Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. J Biol Chem (2005) 1.68
Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation. Science (2010) 1.68
The Rho-associated protein kinase p160ROCK is required for centrosome positioning. J Cell Biol (2002) 1.65
The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation. EMBO J (2003) 1.60
Global regulatory impact of ClpP protease of Staphylococcus aureus on regulons involved in virulence, oxidative stress response, autolysis, and DNA repair. J Bacteriol (2006) 1.58
A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites. Mol Microbiol (2002) 1.52
Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange. J Physiol (2005) 1.49
Peptide-mediated interference with influenza A virus polymerase. J Virol (2007) 1.48
Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation. J Cell Sci (2005) 1.46
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J (2006) 1.45
Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med (2004) 1.37
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation. J Biol Chem (2004) 1.25
The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. J Exp Med (2004) 1.24
Integrin-mediated invasion of Staphylococcus aureus into human cells requires Src family protein-tyrosine kinases. J Biol Chem (2003) 1.23
Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium. J Biol Chem (2003) 1.23
CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol (2005) 1.17
Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. PLoS One (2009) 1.13
Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association. Angew Chem Int Ed Engl (2010) 1.13
Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity. Antiviral Res (2010) 1.12
A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics (2009) 1.11
Inference of genetic regulatory networks with recurrent neural network models using particle swarm optimization. IEEE/ACM Trans Comput Biol Bioinform (2007) 1.11
Minimum information about a protein affinity reagent (MIAPAR). Nat Biotechnol (2010) 1.10
BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responses. EMBO J (2007) 1.10
Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA (2006) 1.09
Molecular and functional characterization of clathrin- and AP-2-binding determinants within a disordered domain of auxilin. J Biol Chem (2003) 1.08
High-avidity human serum antibodies recognizing linear epitopes of Borna disease virus proteins. Biol Psychiatry (2002) 1.08
Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome. J Immunol (2007) 1.08
Quantification of bacterial invasion into adherent cells by flow cytometry. J Microbiol Methods (2005) 1.06
Immunization of pigs to prevent disease in humans: construction and protective efficacy of a Salmonella enterica serovar Typhimurium live negative-marker vaccine. Infect Immun (2007) 1.04
Toxoplasma gondii actively inhibits neuronal function in chronically infected mice. PLoS One (2012) 1.04
Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion molecule isoforms. Infect Immun (2007) 1.04
Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility. Immunity (2009) 1.03
The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters. J Virol (2009) 1.01
Streptococcus pneumoniae enolase is important for plasminogen binding despite low abundance of enolase protein on the bacterial cell surface. Microbiology (2006) 1.00
Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits. Hum Mol Genet (2011) 0.99
Identification of high-affinity PB1-derived peptides with enhanced affinity to the PA protein of influenza A virus polymerase. Antimicrob Agents Chemother (2010) 0.99
Microscopic quantification of bacterial invasion by a novel antibody-independent staining method. J Microbiol Methods (2004) 0.99
14-3-3 proteins are constituents of the insoluble glycoprotein framework of the chlamydomonas cell wall. Plant Cell (2003) 0.99
Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling. J Biol Chem (2004) 0.99
Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus. PLoS One (2009) 0.98
An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA. Front Cell Infect Microbiol (2012) 0.98
CEACAM3: an innate immune receptor directed against human-restricted bacterial pathogens. Int J Med Microbiol (2008) 0.97
The CEACAM1 transmembrane domain, but not the cytoplasmic domain, directs internalization of human pathogens via membrane microdomains. Cell Microbiol (2007) 0.97
N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus. J Hepatol (2010) 0.97
Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha. Mol Biol Cell (2006) 0.97
Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens. J Cell Sci (2010) 0.96
Neurofilaments bind tubulin and modulate its polymerization. J Neurosci (2009) 0.96
The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation. Gastroenterology (2011) 0.95
Identification and characterization of the Cdc42-binding site of IQGAP1. Biochem Biophys Res Commun (2003) 0.94
Protocadherin 12 (VE-cadherin 2) is expressed in endothelial, trophoblast, and mesangial cells. Exp Cell Res (2005) 0.94
Systematic delineation of a calmodulin peptide interaction. J Mol Biol (2004) 0.94
AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling. Mol Cell Biol (2008) 0.92
Borna disease virus matrix protein is an integral component of the viral ribonucleoprotein complex that does not interfere with polymerase activity. J Virol (2006) 0.92
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J (2010) 0.92
The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria. PLoS One (2012) 0.92
Integrin-mediated uptake of fibronectin-binding bacteria. Eur J Cell Biol (2011) 0.91
The Lsc RhoGEF mediates signaling from thromboxane A2 to actin polymerization and apoptosis in thymocytes. Eur J Immunol (2005) 0.91
Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes. Chembiochem (2012) 0.91
Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming. J Neuroimmunol (2003) 0.89
CEACAM1 recognition by bacterial pathogens is species-specific. BMC Microbiol (2010) 0.89
Fibroblast migration after myocardial infarction is regulated by transient SPARC expression. J Mol Med (Berl) (2006) 0.89
Profiling of bacterial adhesin--host receptor recognition by soluble immunoglobulin superfamily domains. J Microbiol Methods (2006) 0.89
Phosphatidylinositol 3'-kinase activity is critical for initiating the oxidative burst and bacterial destruction during CEACAM3-mediated phagocytosis. J Biol Chem (2011) 0.88
Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling. BMC Biol (2009) 0.88
Peptide-mediated disruption of NFkappaB/NRF interaction inhibits IL-8 gene activation by IL-1 or Helicobacter pylori. J Immunol (2007) 0.88
Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept. Mol Divers (2009) 0.87
Differential spatial expression and subcellular localization of CtBP family members in rodent brain. PLoS One (2012) 0.86
Isolation of scFv fragments specific to OmpD of Salmonella Typhimurium. Vet Microbiol (2010) 0.86
HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens. Arch Biochem Biophys (2012) 0.86
The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium. Mol Microbiol (2013) 0.86
Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma. Hum Gene Ther (2010) 0.85
High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination. Mol Med (2013) 0.84
Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1. PLoS One (2011) 0.84
Large-scale analysis of protein-protein interactions using cellulose-bound peptide arrays. Adv Biochem Eng Biotechnol (2008) 0.84
Polymeric immunoglobulin receptor-mediated invasion of Streptococcus pneumoniae into host cells requires a coordinate signaling of SRC family of protein-tyrosine kinases, ERK, and c-Jun N-terminal kinase. J Biol Chem (2010) 0.84
Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases. Infect Immun (2010) 0.83
Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Ialpha. Pharmacol Ther (2002) 0.83
Myxobacteria: natural pharmaceutical factories. Microb Cell Fact (2012) 0.83
Design of a general-purpose European compound screening library for EU-OPENSCREEN. ChemMedChem (2014) 0.83
Targeting of alpha(v) integrins interferes with FAK activation and smooth muscle cell migration and invasion. Biochem Biophys Res Commun (2005) 0.83
The negative regulator of Borna disease virus polymerase is a non-structural protein. J Gen Virol (2005) 0.82