Published in Diabetes Care on March 15, 2007
Look AHEAD: Action for Health in Diabetes (LookAHEAD) | NCT00017953
Standards of medical care in diabetes--2013. Diabetes Care (2013) 24.85
Standards of medical care in diabetes--2010. Diabetes Care (2010) 24.28
Standards of medical care in diabetes--2011. Diabetes Care (2011) 21.94
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care (2008) 21.05
Standards of medical care in diabetes--2012. Diabetes Care (2012) 20.66
Standards of medical care in diabetes--2009. Diabetes Care (2009) 15.78
Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med (2012) 13.59
Full accounting of diabetes and pre-diabetes in the U.S. population in 1988-1994 and 2005-2006. Diabetes Care (2008) 10.90
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med (2010) 8.77
Diabetes and cancer: a consensus report. Diabetes Care (2010) 6.71
Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: a randomized trial. JAMA (2010) 5.77
Weight loss to treat urinary incontinence in overweight and obese women. N Engl J Med (2009) 5.58
Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care (2011) 5.50
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation (2013) 5.02
Nutrition therapy recommendations for the management of adults with diabetes. Diabetes Care (2013) 4.85
Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2014) 4.30
One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring) (2009) 4.08
Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care (2010) 3.98
Three-Year Outcomes of Bariatric Surgery vs Lifestyle Intervention for Type 2 Diabetes Mellitus Treatment: A Randomized Clinical Trial. JAMA Surg (2015) 3.67
Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring) (2011) 3.62
Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA (2013) 3.57
Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis. Hepatology (2010) 3.55
A randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes: the Sleep AHEAD study. Arch Intern Med (2009) 3.27
Health benefits of gastric bypass surgery after 6 years. JAMA (2012) 3.10
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J (2011) 3.00
American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement--executive summary. Endocr Pract (2013) 2.97
Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy. Circulation (2012) 2.82
Bariatric surgery: an IDF statement for obese Type 2 diabetes. Diabet Med (2011) 2.74
Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med (2009) 2.59
Extended-care programs for weight management in rural communities: the treatment of obesity in underserved rural settings (TOURS) randomized trial. Arch Intern Med (2008) 2.54
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Randomized clinical trials of weight loss maintenance: a review. J Cardiovasc Nurs (2008) 2.43
Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care (2013) 2.33
Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study. Int J Obes (Lond) (2009) 2.32
The medical risks of obesity. Postgrad Med (2009) 2.15
The effect of randomization to weight loss on total mortality in older overweight and obese adults: the ADAPT Study. J Gerontol A Biol Sci Med Sci (2010) 2.12
Behavioral treatment of obesity. Psychiatr Clin North Am (2011) 2.03
Weight loss treatment influences untreated spouses and the home environment: evidence of a ripple effect. Int J Obes (Lond) (2008) 2.02
Effect of a stepped-care intervention approach on weight loss in adults: a randomized clinical trial. JAMA (2012) 2.02
One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Obesity (Silver Spring) (2011) 1.97
Relationship between obesity and diabetes in a US adult population: findings from the National Health and Nutrition Examination Survey, 1999-2006. Obes Surg (2011) 1.85
Weight loss prevents urinary incontinence in women with type 2 diabetes: results from the Look AHEAD trial. J Urol (2012) 1.85
Transtheoretical model-based multiple behavior intervention for weight management: effectiveness on a population basis. Prev Med (2007) 1.79
Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care (2011) 1.78
Translating weight loss and physical activity programs into the community to preserve mobility in older, obese adults in poor cardiovascular health. Arch Intern Med (2011) 1.78
Intensive lifestyle intervention improves physical function among obese adults with knee pain: findings from the Look AHEAD trial. Obesity (Silver Spring) (2010) 1.78
Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study. Circulation (2009) 1.77
The role of obesity in cancer survival and recurrence. Cancer Epidemiol Biomarkers Prev (2012) 1.75
Prevention and management of type 2 diabetes: dietary components and nutritional strategies. Lancet (2014) 1.75
The effect of a structured behavioral intervention on poorly controlled diabetes: a randomized controlled trial. Arch Intern Med (2011) 1.71
The science of sustaining health behavior change: the health maintenance consortium. Am J Health Behav (2010) 1.70
Roux-en-Y gastric bypass for diabetes (the Diabetes Surgery Study): 2-year outcomes of a 5-year, randomised, controlled trial. Lancet Diabetes Endocrinol (2015) 1.64
The efficacy of a daily self-weighing weight loss intervention using smart scales and e-mail. Obesity (Silver Spring) (2013) 1.60
Behavior matters. Am J Prev Med (2011) 1.58
Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study. Urology (2009) 1.55
Absence of obesity paradox in patients with chronic heart failure and diabetes mellitus: a propensity-matched study. Eur J Heart Fail (2010) 1.55
Bariatric surgery for type 2 diabetes: weighing the impact for obese patients. Cleve Clin J Med (2010) 1.54
Plasma concentrations of trans fatty acids in persons with type 2 diabetes between September 2002 and April 2004. Am J Clin Nutr (2013) 1.51
Combining behavioral weight loss treatment and a commercial program: a randomized clinical trial. Obesity (Silver Spring) (2013) 1.50
Long-term effect of weight loss on obstructive sleep apnea severity in obese patients with type 2 diabetes. Sleep (2013) 1.50
Diabetes: Looking back at Look AHEAD--giving lifestyle a chance. Nat Rev Cardiol (2013) 1.49
The development and description of the comparison group in the Look AHEAD trial. Clin Trials (2011) 1.46
Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery. J Diabetes (2010) 1.46
Attrition from randomized controlled trials of pharmacological weight loss agents: a systematic review and analysis. Obes Rev (2009) 1.46
Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention. Obesity (Silver Spring) (2014) 1.44
Management of type 2 diabetes: evolving strategies for the treatment of patients with type 2 diabetes. Metabolism (2011) 1.41
Roux-en-Y gastric bypass surgery or lifestyle with intensive medical management in patients with type 2 diabetes: feasibility and 1-year results of a randomized clinical trial. JAMA Surg (2014) 1.41
Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties. Cardiovasc Diabetol (2011) 1.41
Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial. JAMA Surg (2014) 1.40
Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes. Diabetes Care (2010) 1.40
Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Diabetes Care (2010) 1.39
Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD. Circ Cardiovasc Genet (2015) 1.38
Obesity-related cardiovascular risk factors after weight loss: a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention. Eur J Endocrinol (2010) 1.37
A statewide intervention reduces BMI in adults: Shape Up Rhode Island results. Obesity (Silver Spring) (2009) 1.37
The Colon Health and Life-Long Exercise Change trial: a randomized trial of the National Cancer Institute of Canada Clinical Trials Group. Curr Oncol (2008) 1.37
Effectiveness of a motivational interviewing intervention on weight loss, physical activity and cardiovascular disease risk factors: a randomised controlled trial with a 12-month post-intervention follow-up. Int J Behav Nutr Phys Act (2013) 1.36
Improving weight loss outcomes of community interventions by incorporating behavioral strategies. Am J Public Health (2010) 1.36
Weight change in diabetes and glycemic and blood pressure control. Diabetes Care (2008) 1.34
Detection and interpretation of shared genetic influences on 42 human traits. Nat Genet (2016) 1.32
Type 2 diabetes can be prevented with early pharmacological intervention. Diabetes Care (2011) 1.31
Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy. Ageing Res Rev (2010) 1.31
Lifestyle and pharmacological approaches to weight loss: efficacy and safety. J Clin Endocrinol Metab (2008) 1.30
The CALERIE Study: design and methods of an innovative 25% caloric restriction intervention. Contemp Clin Trials (2011) 1.30
Evidence-based practice guideline for the treatment of CKD. Clin Exp Nephrol (2009) 1.29
Randomized controlled trial of a comprehensive home environment-focused weight-loss program for adults. Health Psychol (2012) 1.27
Recent advances in internet-delivered, evidence-based weight control programs for adults. J Diabetes Sci Technol (2009) 1.26
Intentional weight loss and changes in symptoms of depression: a systematic review and meta-analysis. Int J Obes (Lond) (2011) 1.25
Migraine and obesity: epidemiology, possible mechanisms and the potential role of weight loss treatment. Obes Rev (2011) 1.24
Effects of counseling techniques on patients' weight-related attitudes and behaviors in a primary care clinic. Patient Educ Couns (2011) 1.24
Activity patterns of obese adults with type 2 diabetes in the look AHEAD study. Med Sci Sports Exerc (2010) 1.24
Cost-effectiveness of lifestyle modification in diabetic patients. Diabetes Care (2009) 1.23
Implications of the diabetes prevention program and Look AHEAD clinical trials for lifestyle interventions. J Am Diet Assoc (2008) 1.22
The long-term effectiveness of a lifestyle intervention in severely obese individuals. Am J Med (2013) 1.22
A 1-year lifestyle intervention for weight loss in individuals with type 2 diabetes reduces high C-reactive protein levels and identifies metabolic predictors of change: from the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 1.21
A comparison of maintenance-tailored therapy (MTT) and standard behavior therapy (SBT) for the treatment of obesity. Prev Med (2009) 1.21
Comparing behavioral weight loss modalities: incremental cost-effectiveness of an internet-based versus an in-person condition. Obesity (Silver Spring) (2011) 1.21
Behavioral and pharmacologic therapies for obesity. Nat Rev Endocrinol (2010) 1.20
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med (2002) 101.79
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem (1972) 95.79
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med (2001) 56.11
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health. Obes Res (1998) 50.73
The Diabetes Prevention Program (DPP): description of lifestyle intervention. Diabetes Care (2002) 11.65
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring) (2006) 8.25
Standards of medical care in diabetes. Diabetes Care (2005) 5.98
Achieving weight and activity goals among diabetes prevention program lifestyle participants. Obes Res (2004) 5.74
Effect of exercise duration and intensity on weight loss in overweight, sedentary women: a randomized trial. JAMA (2003) 5.45
Trends in the prevalence and ratio of diagnosed to undiagnosed diabetes according to obesity levels in the U.S. Diabetes Care (2004) 4.84
Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men. Am J Clin Nutr (1999) 4.64
Baseline characteristics of the randomised cohort from the Look AHEAD (Action for Health in Diabetes) study. Diab Vasc Dis Res (2006) 4.30
Physical activity and weight loss: does prescribing higher physical activity goals improve outcome? Am J Clin Nutr (2003) 3.71
Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes. Ann Intern Med (2000) 3.66
Weight management using a meal replacement strategy: meta and pooling analysis from six studies. Int J Obes Relat Metab Disord (2003) 3.21
Effects of intermittent exercise and use of home exercise equipment on adherence, weight loss, and fitness in overweight women: a randomized trial. JAMA (1999) 2.93
Strengthening behavioral interventions for weight loss: a randomized trial of food provision and monetary incentives. J Consult Clin Psychol (1993) 2.88
Translating lifestyle intervention to practice in obese patients with type 2 diabetes: Improving Control with Activity and Nutrition (ICAN) study. Diabetes Care (2004) 2.84
Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: the Midwest Exercise Trial. Arch Intern Med (2003) 2.83
Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity. Diabetes (2003) 2.38
Fitness and fatness as predictors of mortality from all causes and from cardiovascular disease in men and women in the lipid research clinics study. Am J Epidemiol (2002) 2.35
Perceived exertion. Exerc Sport Sci Rev (1974) 2.23
Metabolic and weight-loss effects of a long-term dietary intervention in obese patients. Am J Clin Nutr (1999) 1.92
Changes in BMI and weight before and after the development of type 2 diabetes. Diabetes Care (2001) 1.89
The effect of short periods of caloric restriction on weight loss and glycemic control in type 2 diabetes. Diabetes Care (1998) 1.68
Early lifestyle intervention in patients with non-insulin-dependent diabetes mellitus and impaired glucose tolerance. Ann Med (1996) 1.62
Comparison of obese NIDDM and nondiabetic women: short- and long-term weight loss. Obes Res (1995) 1.60
Effects of regular walking on cardiovascular risk factors and body composition in normoglycemic women and women with type 2 diabetes. Diabetes Care (1999) 1.51
Behavioral treatment of obesity. Its application to type II diabetes. Diabetes Care (1993) 1.26
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med (2002) 101.79
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37
Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care (2003) 29.49
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69
A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med (2015) 19.14
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med (2006) 19.09
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med (2006) 18.25
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet (2009) 15.00
Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med (2010) 13.25
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med (2009) 12.38
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. Ann Intern Med (2004) 10.35
Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med (2003) 10.06
Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. N Engl J Med (2000) 10.05
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet (2008) 9.50
Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med (2012) 9.46
A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med (2003) 9.23
Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab (2002) 8.90
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med (2010) 8.77
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med (2010) 8.70
Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol (2003) 8.64
Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med (2007) 8.59
Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care (2010) 8.52
Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program. Diabetes Care (2007) 8.43
The epidemiology of obesity. Gastroenterology (2007) 8.35
The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring) (2006) 8.25
The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol (2003) 8.23
Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med (2011) 8.19
Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med (2009) 8.06
Systematic review: an evaluation of major commercial weight loss programs in the United States. Ann Intern Med (2005) 8.00
Comparative effectiveness of weight-loss interventions in clinical practice. N Engl J Med (2011) 7.81
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med (2006) 7.75
Readability standards for informed-consent forms as compared with actual readability. N Engl J Med (2003) 7.58
A clinical trial to maintain glycemic control in youth with type 2 diabetes. N Engl J Med (2012) 7.51
The Women's Health Initiative Observational Study: baseline characteristics of participants and reliability of baseline measures. Ann Epidemiol (2003) 7.49
Association of weight status with mortality in adults with incident diabetes. JAMA (2012) 7.49
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med (2009) 7.45
Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect (2005) 7.43
Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12
Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care (2006) 7.09
Effects of Internet behavioral counseling on weight loss in adults at risk for type 2 diabetes: a randomized trial. JAMA (2003) 7.07
Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control. Endocr Pract (2009) 7.06
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation (2010) 6.86
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63
The prevalence of diabetic retinopathy among adults in the United States. Arch Ophthalmol (2004) 6.53
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med (2007) 6.09