Published in Biochem Biophys Res Commun on March 13, 2007
The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits. BMC Biochem (2012) 0.87
Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells. Genesis (2013) 0.80
Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis. J Biol Chem (2016) 0.76
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat Cell Biol (2002) 5.37
Autophagy-deficient mice develop multiple liver tumors. Genes Dev (2011) 4.64
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol (2011) 2.64
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression. Genes Dev (2005) 1.99
A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res (2005) 1.69
Clinical and genetic spectrum of Birt-Hogg-Dube syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature. J Med Genet (2010) 1.61
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels. Autophagy (2011) 1.59
Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis. J Hum Genet (2002) 1.57
High-grade lung adenocarcinoma with fetal lung-like morphology: clinicopathologic, immunohistochemical, and molecular analyses of 17 cases. Am J Surg Pathol (2013) 1.53
A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem (2009) 1.47
Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice. Mol Cell Biol (2008) 1.46
MESOMARK kit detects C-ERC/mesothelin, but not SMRP with C-terminus. Biochem Biophys Res Commun (2008) 1.46
A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer. Proc Natl Acad Sci U S A (2004) 1.40
Clinical effects of tumor-associated macrophages and dendritic cells on renal cell carcinoma. Anticancer Res (2003) 1.37
Malignant perivascular epithelioid cell tumor of the colon: report of a case with molecular analysis. Pathol Int (2006) 1.33
Carcinosarcoma of the rectosigmoid colon: report of a case. Surg Today (2003) 1.27
Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions. Circulation (2003) 1.22
Epidemiology of hepatocellular carcinoma in Japan and Korea. A review. Oncology (2008) 1.18
The up-regulation of Y-box binding proteins (DNA binding protein A and Y-box binding protein-1) as prognostic markers of hepatocellular carcinoma. Clin Cancer Res (2005) 1.18
Sensitive and specific new enzyme-linked immunosorbent assay for N-ERC/mesothelin increases its potential as a useful serum tumor marker for mesothelioma. Clin Cancer Res (2008) 1.17
Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex. Nat Commun (2012) 1.16
Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma. Pathol Int (2009) 1.14
Accumulation of phosphorylated alpha-synuclein in dopaminergic neurons of transgenic mice that express human alpha-synuclein. J Neurosci Res (2007) 1.14
Clinical and pathological features of glycogen-rich clear cell carcinoma of the breast. Breast Cancer (2005) 1.13
Transgenic-cloned pigs systemically expressing red fluorescent protein, Kusabira-Orange. Cloning Stem Cells (2008) 1.13
Novel ELISA system for detection of N-ERC/mesothelin in the sera of mesothelioma patients. Cancer Sci (2006) 1.12
Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells. J Biol Chem (2006) 1.10
Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation. Int J Mol Med (2006) 1.10
Transcription of dbpA, a Y box binding protein, is positively regulated by E2F1: implications in hepatocarcinogenesis. Biochem Biophys Res Commun (2004) 1.06
Clinical and pathologic features of invasive micropapillary carcinoma. Breast Cancer (2004) 1.05
Identification of the coding sequences responsible for Tsc2-mediated tumor suppression using a transgenic rat system. Hum Mol Genet (2002) 1.04
Overexpression of GLUT-1 in the invasion front is associated with depth of oral squamous cell carcinoma and prognosis. J Oral Pathol Med (2009) 1.04
Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway. J Biol Chem (2006) 1.04
GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress. Int J Mol Med (2007) 1.03
Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM). Sci Transl Med (2012) 1.03
Clinicopathological analyses in patients with other iatrogenic immunodeficiency-associated lymphoproliferative diseases and rheumatoid arthritis. Leuk Lymphoma (2011) 1.00
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer. PLoS One (2012) 1.00
Frequent hypermethylation of RASSF1A in early flat-type colorectal tumors. Oncogene (2004) 0.99
Immunophenotype of lymphocytic infiltration in medullary carcinoma of the breast. Virchows Arch (2004) 0.99
Filtered QRS duration on signal-averaged electrocardiography correlates with ventricular dyssynchrony assessed by tissue Doppler imaging in patients with reduced ventricular ejection fraction. J Electrocardiol (2009) 0.99
Hyperactivated STAT3 in ALK-positive diffuse large B-cell lymphoma with clathrin-ALK fusion. Hum Pathol (2008) 0.99
Activated iodosylbenzene monomer as an ozone equivalent: oxidative cleavage of carbon-carbon double bonds in the presence of water. J Am Chem Soc (2007) 0.98
C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma. J Gastroenterol (2013) 0.97
Knockdown of COPA, identified by loss-of-function screen, induces apoptosis and suppresses tumor growth in mesothelioma mouse model. Genomics (2010) 0.97
Tuberous sclerosis complex 2 loss-of-function mutation regulates reactive oxygen species production through Rac1 activation. Biochem Biophys Res Commun (2008) 0.96
Osteopontin plays an important role in the development of medial thickening and neointimal formation. Circ Res (2002) 0.96
A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis. Hum Pathol (2006) 0.95
The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma. J Thorac Dis (2013) 0.95
Pseudo-Meigs' syndrome caused by ovarian metastasis from colon cancer: report of a case. Surg Today (2003) 0.95
Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice. J Immunol (2004) 0.95
Molecular tumor markers for asbestos-related mesothelioma: serum diagnostic markers. Pathol Int (2006) 0.93
LRRN4 and UPK3B are markers of primary mesothelial cells. PLoS One (2011) 0.93
Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt-Hogg-Dubé syndrome. Virchows Arch (2006) 0.93
Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway. J Virol (2007) 0.92
Osteopontin is strongly expressed by alveolar macrophages in the lungs of acute respiratory distress syndrome. Lung (2004) 0.91
Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo. Cancer Sci (2009) 0.91
Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product. FEBS Lett (2010) 0.91
Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway. Biochem Biophys Res Commun (2009) 0.91
A clinical study on serum prostaglandin E2 with low-level laser therapy. Photomed Laser Surg (2004) 0.90
Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis. Int J Oncol (2002) 0.90
Osthole prevents anti-Fas antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway. Biochem Pharmacol (2003) 0.90
ERC/mesothelin as a marker for chemotherapeutic response in patients with mesothelioma. Anticancer Res (2009) 0.90
Diagnostic accuracy of multidetector-row computed tomography for hilar cholangiocarcinoma. J Gastroenterol Hepatol (2010) 0.89
Expression of E-cadherin, alpha-catenin, and beta-catenin in tubulolobular carcinoma of the breast. Virchows Arch (2006) 0.89
Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma. Oncol Rep (2008) 0.89
The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation. Biochem Biophys Res Commun (2007) 0.88
Establishment of novel mAb to human ERC/mesothelin useful for study and diagnosis of ERC/mesothelin-expressing cancers. Pathol Int (2009) 0.88
Lymphomatoid granulomatosis and diffuse alveolar damage associated with methotrexate therapy in a patient with rheumatoid arthritis. Clin Rheumatol (2007) 0.88
Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice. Carcinogenesis (2010) 0.88
Natural history of the Nihon rat model of BHD. Curr Mol Med (2004) 0.88
Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic recombination. Proc Natl Acad Sci U S A (2004) 0.87
Gene expression profile of DNA binding protein A transgenic mice. Int J Oncol (2006) 0.87
Renal carcinogenesis: genotype, phenotype and dramatype. Cancer Sci (2003) 0.87
Mucosa-associated lymphoid tissue lymphoma of the appendix vermiformis. Int Surg (2010) 0.87
Primary diffuse large B-cell lymphoma of the breast. Breast Cancer (2007) 0.87
Recent advances in the management of chronic hepatitis B. Hepat Mon (2011) 0.87
An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas. Biochem Biophys Res Commun (2009) 0.86
Voluntary exercise ameliorates the progression of atherosclerotic lesion formation via anti-inflammatory effects in apolipoprotein E-deficient mice. J Atheroscler Thromb (2010) 0.85
Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis. Oncogene (2004) 0.85
Blood tests for asbestos-related mesothelioma. Oncology (2007) 0.85
Pagetoid spread to oral mucosa from submandibular gland salivary duct carcinoma: a case report. Hum Pathol (2009) 0.84
ERC/mesothelin is expressed in human gastric cancer tissues and cell lines. Oncol Rep (2013) 0.84