Pharmacological aspects of the effects of tramadol on G-protein coupled receptors.

PubWeight™: 0.94‹?›

🔗 View Article (PMID 17380034)

Published in J Pharmacol Sci on March 01, 2007

Authors

Kouichiro Minami1, Yasuhito Uezono, Yoichi Ueta

Author Affiliations

1: Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Japan. kminami@med.uoeh-u.ac.jp

Articles by these authors

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab (2007) 3.43

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. J Clin Invest (2004) 1.88

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat Med (2004) 1.48

Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42

Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms. Proc Natl Acad Sci U S A (2005) 1.22

REVIEW: Oxytocin: Crossing the bridge between basic science and pharmacotherapy. CNS Neurosci Ther (2010) 1.19

The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors. Anesth Analg (2002) 1.19

Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. Arterioscler Thromb Vasc Biol (2004) 1.15

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells. J Clin Invest (2005) 1.12

Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons. Regul Pept (2004) 1.12

mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis. J Pharmacol Sci (2008) 1.12

Increased expression of a Myc target gene Mina53 in human colon cancer. Am J Pathol (2004) 1.10

Chaos of vowel /a/ in Japanese patients with depression: a preliminary study. J Occup Health (2005) 1.09

Centrally and peripherally administered ghrelin potently inhibits water intake in rats. Endocrinology (2007) 1.03

Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J (2005) 1.02

Synchronized bursts of miniature inhibitory postsynaptic currents. J Physiol (2010) 0.98

GABA is excitatory in adult vasopressinergic neuroendocrine cells. J Neurosci (2012) 0.96

Endogenous prolactin-releasing peptide regulates food intake in rodents. J Clin Invest (2008) 0.93

Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. J Biol Chem (2011) 0.92

V₂ receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions. Sci Signal (2011) 0.91

Developmental and aging change of orexin-A and -B immunoreactive neurons in the male rat hypothalamus. Neurosci Lett (2009) 0.91

Short-term sleep disturbance enhances brain-derived neurotrophic factor gene expression in rat hippocampus by acting as internal stressor. J Mol Neurosci (2003) 0.91

Effects of LPS stimulation on the expression of prostaglandin carriers in the cells of the blood-brain and blood-cerebrospinal fluid barriers. J Appl Physiol (1985) (2005) 0.90

Central diabetes insipidus associated with impaired renal aquaporin-1 expression in mice lacking liver X receptor β. Proc Natl Acad Sci U S A (2012) 0.90

Nitric oxide synthases and cardiovascular diseases: insights from genetically modified mice. Circ J (2009) 0.90

The effects of the tramadol metabolite O-desmethyl tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M1 or M3 receptors. Anesth Analg (2005) 0.89

The effects of apelin on the electrical activity of hypothalamic magnocellular vasopressin and oxytocin neurons and somatodendritic Peptide release. Endocrinology (2008) 0.89

Prostate cancer cells increase androgen sensitivity by increase in nuclear androgen receptor and androgen receptor coactivators; a possible mechanism of hormone-resistance of prostate cancer cells. Cancer Invest (2007) 0.88

Segregation of calcium signalling mechanisms in magnocellular neurones and terminals. Cell Calcium (2012) 0.87

Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus. Life Sci (2003) 0.87

Reduced carnitine level causes death from hypoglycemia: possible involvement of suppression of hypothalamic orexin expression during weaning period. Endocr J (2007) 0.87

Centrally administered neuromedin U activates neurosecretion and induction of c-fos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat. Endocrinology (2002) 0.86

Adrenomedullin 2 protects rat cerebral endothelial cells from oxidative damage in vitro. Brain Res (2006) 0.86

Reduced nitric oxide synthase in the brainstem contributes to enhanced sympathetic drive in rats with heart failure. J Cardiovasc Pharmacol (2003) 0.86

Lithium inhibits function of voltage-dependent sodium channels and catecholamine secretion independent of glycogen synthase kinase-3 in adrenal chromaffin cells. Neuropharmacology (2007) 0.85

Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus. J Physiol (2010) 0.85

Adenine nucleotide-induced activation of adenosine A(2B) receptors expressed in Xenopus laevis oocytes: involvement of a rapid and localized adenosine formation by ectonucleotidases. Mol Pharmacol (2002) 0.85

Inhibitory effects of tramadol on nicotinic acetylcholine receptors in adrenal chromaffin cells and in Xenopus oocytes expressing alpha 7 receptors. Br J Pharmacol (2002) 0.85

A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells. Anesth Analg (2002) 0.84

Centrally administered ghrelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats. J Physiol Sci (2009) 0.84

Effects of restricted feeding on the activity of hypothalamic Orexin (OX)-A containing neurons and OX2 receptor mRNA level in the paraventricular nucleus of rats. Regul Pept (2002) 0.84

Effects of anesthetics on the function of orexin-1 receptors expressed in Xenopus oocytes. Pharmacology (2007) 0.84

Robust up-regulation of nuclear red fluorescent-tagged fos marks neuronal activation in green fluorescent vasopressin neurons after osmotic stimulation in a double-transgenic rat. Endocrinology (2009) 0.84

Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat. J Pharmacol Sci (2014) 0.83

Regulation of catecholamine synthesis by leptin. Ann N Y Acad Sci (2002) 0.83

Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state. Addict Biol (2011) 0.83

Desensitization of GABA(B) receptor signaling by formation of protein complexes of GABA(B2) subunit with GRK4 or GRK5. J Cell Physiol (2007) 0.83

Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides. Clin Cancer Res (2007) 0.83

The inhibitory effects of tramadol on 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes. Anesth Analg (2004) 0.83

New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line. Am J Physiol Endocrinol Metab (2013) 0.83

Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca2+ elevation in cultured rat dorsal root ganglia cells. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.82

Effects of cholecystokinin (CCK)-8 on hypothalamic oxytocin-secreting neurons in rats lacking CCK-A receptor. Auton Neurosci (2005) 0.82

Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats. J Endocrinol (2006) 0.82

Fos expression in CRF-containing neurons in the rat paraventricular nucleus after central administration of neuromedin U. Stress (2004) 0.82

Sensation of abdominal pain induced by peritoneal carcinomatosis is accompanied by changes in the expression of substance P and μ-opioid receptors in the spinal cord of mice. Anesthesiology (2012) 0.82

The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. Anesth Analg (2014) 0.82

Activation of the neurokinin-1 receptor in rat spinal astrocytes induces Ca2+ release from IP3-sensitive Ca2+ stores and extracellular Ca2+ influx through TRPC3. Neurochem Int (2010) 0.82

Adrenomedullin, an autocrine mediator of blood-brain barrier function. Hypertens Res (2003) 0.81

Transcriptional up-regulation of cell surface Na V 1.7 sodium channels by insulin-like growth factor-1 via inhibition of glycogen synthase kinase-3β in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion. Neuropharmacology (2011) 0.81

Destabilization of Na(v)1.7 sodium channel alpha-subunit mRNA by constitutive phosphorylation of extracellular signal-regulated kinase: negative regulation of steady-state level of cell surface functional sodium channels in adrenal chromaffin cells. Mol Pharmacol (2003) 0.81

Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus. Brain Res (2011) 0.81

Orexin-A augments voltage-gated Ca2+ currents and synergistically increases growth hormone (GH) secretion with GH-releasing hormone in primary cultured ovine somatotropes. Endocrinology (2002) 0.81

History of the G protein-coupled receptor (GPCR) assays from traditional to a state-of-the-art biosensor assay. J Pharmacol Sci (2014) 0.81

Highly visible expression of an oxytocin-monomeric red fluorescent protein 1 fusion gene in the hypothalamus and posterior pituitary of transgenic rats. Endocrinology (2011) 0.81

Obstructive sleep apnea-hypopnea syndrome patients with overweight and hypertension in a Japanese workplace. J Occup Health (2007) 0.81

Inhibitory effects of isoflavones on tumor growth and cachexia in newly established cachectic mouse models carrying human stomach cancers. Nutr Cancer (2013) 0.80

Exposure to hypergravity during the preweaning but not postweaning period reduces vestibular-related stress responses in rats. J Appl Physiol (1985) (2013) 0.80

Effects of the intravenously administered anaesthetics ketamine, propofol, and thiamylal on the cortical renal blood flow in rats. Pharmacology (2003) 0.80

The clinical use of Kampo medicines (traditional Japanese herbal treatments) for controlling cancer patients' symptoms in Japan: a national cross-sectional survey. BMC Complement Altern Med (2012) 0.80

Diurnal changes of arginine vasopressin-enhanced green fluorescent protein fusion transgene expression in the rat suprachiasmatic nucleus. Peptides (2010) 0.80

Pre-treatment of adrenomedullin suppresses cerebral edema caused by transient focal cerebral ischemia in rats detected by magnetic resonance imaging. Brain Res Bull (2010) 0.80

Regulatory mechanism of the arginine vasopressin-enhanced green fluorescent protein fusion gene expression in acute and chronic stress. Peptides (2009) 0.80

Chronic lithium treatment up-regulates cell surface Na(V)1.7 sodium channels via inhibition of glycogen synthase kinase-3 in adrenal chromaffin cells: enhancement of Na(+) influx, Ca(2+) influx and catecholamine secretion after lithium withdrawal. Neuropharmacology (2009) 0.80

Distribution of orexins-containing fibers and contents of orexins in the rat olfactory bulb. Neurosci Res (2008) 0.80

Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat. J Neurosci (2009) 0.80

Expressions of the prepro-orexin and orexin type 2 receptor genes in obese rat. Peptides (2002) 0.80

Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures. Brain Res (2011) 0.80

Selective blockade of nicotinic acetylcholine receptors by pimobendan, a drug for the treatment of heart failure: reduction of catecholamine secretion and synthesis in adrenal medullary cells. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.80

Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats. Int J Cancer (2011) 0.79

Effects of food deprivation on the hypothalamic feeding-regulating peptides gene expressions in serotonin depleted rats. J Physiol Sci (2013) 0.79

Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats. Peptides (2007) 0.79

Effects of sevoflurane on voltage-gated sodium channel Na(v)1.8, Na(v)1.7, and Na(v)1.4 expressed in Xenopus oocytes. J Anesth (2011) 0.79

The recent progress in research on effects of anesthetics and analgesics on G protein-coupled receptors. J Anesth (2012) 0.79

Lysophosphatidic acid-LPA1 receptor-Rho-Rho kinase-induced up-regulation of Nav1.7 sodium channel mRNA and protein in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion. J Neurochem (2007) 0.79

Activation of extracellular signal-regulated kinases is essential for pressure-induced proliferation of vascular smooth muscle cells. Eur J Pharmacol (2002) 0.79

Induction of galanin-like peptide gene expression in the rat posterior pituitary gland during endotoxin shock and adjuvant arthritis. Brain Res Mol Brain Res (2003) 0.79

Characterization of GABA(B) receptors involved in inhibition of motility associated with acetylcholine release in the dog small intestine: possible existence of a heterodimer of GABA(B1) and GABA(B2) subunits. J Pharmacol Sci (2004) 0.79

Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary. J Endocrinol (2009) 0.79

Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus. Brain Res (2008) 0.79

Molecular characterization and biological function of neuroendocrine regulatory peptide-3 in the rat. Endocrinology (2012) 0.79

Sevoflurane inhibits the µ-opioid receptor function expressed in Xenopus oocytes. Pharmacology (2011) 0.79

Analysis of the effects of anesthetics and ethanol on mu-opioid receptor. J Pharmacol Sci (2010) 0.79

Autocrine peptide mediators of cerebral endothelial cells and their role in the regulation of blood-brain barrier. Peptides (2005) 0.78