Published in Cancer Biol Ther on February 14, 2007
Alkaloids isolated from natural herbs as the anticancer agents. Evid Based Complement Alternat Med (2012) 1.13
Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells. Sci Rep (2014) 0.99
Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent. Br J Pharmacol (2009) 0.92
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide. Mol Cancer (2010) 0.83
Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination. World J Gastroenterol (2014) 0.80
Berberis libanotica Ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells. PLoS One (2014) 0.79
A Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor Activity. Sci Rep (2016) 0.77
Effects of crude extracts from medicinal herbs Rhazya stricta and Zingiber officinale on growth and proliferation of human brain cancer cell line in vitro. Biomed Res Int (2014) 0.77
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med (2005) 28.73
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature (2003) 22.89
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med (2003) 14.60
Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med (2011) 13.18
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol (2007) 11.14
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol (2009) 6.74
IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med (2007) 3.69
From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal. Nature (2009) 3.18
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol (2012) 3.09
Person-to-person transmission of severe fever with thrombocytopenia syndrome bunyavirus through blood contact. Clin Infect Dis (2011) 2.59
Clinical progress and risk factors for death in severe fever with thrombocytopenia syndrome patients. J Infect Dis (2012) 2.49
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. J Immunol (2009) 2.39
Severe fever with thrombocytopenia syndrome virus among domesticated animals, China. Emerg Infect Dis (2013) 2.35
Early diagnosis of novel SFTS bunyavirus infection by quantitative real-time RT-PCR assay. J Clin Virol (2011) 2.19
Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis. Clin Cancer Res (2010) 2.07
Sexually transmitted disease prevalence and characteristics of market vendors in eastern China. Sex Transm Dis (2003) 2.02
Study of severe and rare complications of transarterial chemoembolization (TACE) for liver cancer. Eur J Radiol (2006) 1.95
'Social evils' and harm reduction: the evolving policy environment for human immunodeficiency virus prevention among injection drug users in China and Vietnam. Addiction (2007) 1.85
Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. Neurosci Lett (2009) 1.78
Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors. J Biol Chem (2003) 1.77
Chiral separation of tamsulosin isomers by HPLC using cellulose tris (3,5-dimethhylphenylcarbamate) as a chiral stationary phase. J Pharm Biomed Anal (2004) 1.75
Draft genome of the kiwifruit Actinidia chinensis. Nat Commun (2013) 1.72
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res (2013) 1.72
Identification of influenza A nucleoprotein as an antiviral target. Nat Biotechnol (2010) 1.71
Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model. Proc Natl Acad Sci U S A (2012) 1.71
Growth arrest induced by C75, A fatty acid synthase inhibitor, was partially modulated by p38 MAPK but not by p53 in human hepatocellular carcinoma. Cancer Biol Ther (2006) 1.70
Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits. Nat Neurosci (2006) 1.70
Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studies. Int J Cancer (2011) 1.69
EEG and MEG coherence: measures of functional connectivity at distinct spatial scales of neocortical dynamics. J Neurosci Methods (2007) 1.68
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients. Cochrane Database Syst Rev (2015) 1.67
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nat Neurosci (2010) 1.67
Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer. Cancer Prev Res (Phila) (2013) 1.66
The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease. Mol Cell Neurosci (2007) 1.66
A DNAzyme that walks processively and autonomously along a one-dimensional track. Angew Chem Int Ed Engl (2005) 1.65
DelPhi: a comprehensive suite for DelPhi software and associated resources. BMC Biophys (2012) 1.64
PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo. Cancer Biol Ther (2005) 1.64
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity (2010) 1.64
Prognostic significance of serum gamma-glutamyl transferase in patients with intermediate hepatocellular carcinoma treated with transcatheter arterial chemoembolization. Eur J Gastroenterol Hepatol (2011) 1.63
Neuroimmunophilin ligands protect cavernous nerves after crush injury in the rat: new experimental paradigms. Eur Urol (2006) 1.63
Host cytokine storm is associated with disease severity of severe fever with thrombocytopenia syndrome. J Infect Dis (2012) 1.62
Sequence comparison between the extracellular domain of M2 protein human and avian influenza A virus provides new information for bivalent influenza vaccine design. Microbes Infect (2004) 1.58
Robust discrimination between self and non-self neurites requires thousands of Dscam1 isoforms. Nature (2009) 1.54
Novel bunyavirus in domestic and captive farmed animals, Minnesota, USA. Emerg Infect Dis (2013) 1.53
Reducing HIV infection among new injecting drug users in the China-Vietnam Cross Border Project. AIDS (2007) 1.53
MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis (2011) 1.51
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. J Am Chem Soc (2012) 1.50
Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis. Blood (2008) 1.50
Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis. Am J Pathol (2009) 1.47
Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium. Structure (2011) 1.46
Impact of warming blood transfusion and infusion toward cerebral oxygen metabolism and cognitive recovery in the perioperative period of elderly knee replacement. J Orthop Surg Res (2014) 1.45
Effective connectivity of brain networks during self-initiated movement in Parkinson's disease. Neuroimage (2010) 1.44
A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol (2010) 1.44
Contribution of epidermal stem cells to hypertrophic scars pathogenesis. Med Hypotheses (2009) 1.42
2-{4-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-yl-idene)methyl-amino]phen-yl}acetonitrile. Acta Crystallogr Sect E Struct Rep Online (2009) 1.41
Heat stress-induced response of the proteomes of leaves from Salvia splendens Vista and King. Proteome Sci (2013) 1.41
Coronary computed tomography angiography---a promising imaging modality in diagnosing coronary artery disease. J Chin Med Assoc (2008) 1.40
Parkinson's disease patients with pain suffer from more severe non-motor symptoms. Neurol Sci (2014) 1.40
Induction of blood brain barrier tight junction protein alterations by CD8 T cells. PLoS One (2008) 1.38
Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion. J Biol Chem (2008) 1.38
4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin. J Biol Chem (2002) 1.37
Structural features of human initiation factor 4E, studied by X-ray crystal analyses and molecular dynamics simulations. J Mol Biol (2003) 1.37
Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies. BMC Cancer (2010) 1.35
Pores and ridges: high-resolution fingerprint matching using level 3 features. IEEE Trans Pattern Anal Mach Intell (2007) 1.35
Interaction between NFκB and NFAT coordinates cardiac hypertrophy and pathological remodeling. Circ Res (2012) 1.35
Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats. Drug Metab Dispos (2009) 1.34
Generation, characterization and epitope mapping of two neutralizing and protective human recombinant antibodies against influenza A H5N1 viruses. PLoS One (2009) 1.33
On the Dielectric "Constant" of Proteins: Smooth Dielectric Function for Macromolecular Modeling and Its Implementation in DelPhi. J Chem Theory Comput (2013) 1.32
Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro. Antiviral Res (2009) 1.32
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities. Drug Metab Dispos (2003) 1.32
Hematopoietic gene expression profile in zebrafish kidney marrow. Proc Natl Acad Sci U S A (2004) 1.31
Correlates of HIV status among injection drug users in a border region of southern China and northern Vietnam. J Acquir Immune Defic Syndr (2005) 1.31
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proc Natl Acad Sci U S A (2014) 1.30
Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer. Cancer Prev Res (Phila) (2011) 1.30
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist. Anal Biochem (2004) 1.29
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PLoS One (2008) 1.29
Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections. BMC Microbiol (2006) 1.27
Patterns of HIV prevalence and HIV risk behaviors among injection drug users prior to and 24 months following implementation of cross-border HIV prevention interventions in northern Vietnam and southern China. AIDS Educ Prev (2006) 1.27
Discovery of LFF571: an investigational agent for Clostridium difficile infection. J Med Chem (2012) 1.26
[Isolation, identification and characterization of SFTS bunyavirus from ticks collected on the surface of domestic animals]. Bing Du Xue Bao (2012) 1.26
Molecular basis of the interaction of Saccharomyces cerevisiae Eaf3 chromo domain with methylated H3K36. J Biol Chem (2008) 1.26
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation. Protein Sci (2006) 1.25
Virtual screening on natural products for discovering active compounds and target information. Curr Med Chem (2003) 1.25
comK prophage junction fragments as markers for Listeria monocytogenes genotypes unique to individual meat and poultry processing plants and a model for rapid niche-specific adaptation, biofilm formation, and persistence. Appl Environ Microbiol (2011) 1.25
A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer. Proteomics Clin Appl (2011) 1.25
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Int J Cancer (2011) 1.24
Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential. Mol Cancer Res (2006) 1.24
Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Neurobiol Dis (2012) 1.23
Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities. Proc Natl Acad Sci U S A (2007) 1.23
Statistical inference and multiple testing correction in classification-based multi-voxel pattern analysis (MVPA): random permutations and cluster size control. Neuroimage (2012) 1.22
Design and synthesis of novel bis(L-amino acid) ester prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) with improved anti-HBV activity. Bioorg Med Chem Lett (2006) 1.21
Vapor-solid growth and characterization of aluminum nitride nanocones. J Am Chem Soc (2005) 1.20
Synthesis of single-crystalline alpha-Si(3)N(4) nanobelts by extended vapour-liquid-solid growth. Nanotechnology (2005) 1.20
Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers. J Am Chem Soc (2011) 1.20
In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury. J Immunol (2008) 1.19
Comparison of the effect of volume conduction on EEG coherence with the effect of field spread on MEG coherence. Stat Med (2007) 1.19
Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms. Nat Prod Rep (2012) 1.18