Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.

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Published in Clin Cancer Res on April 01, 2007

Authors

Jeremy D Heidel1, Joanna Yi-Ching Liu, Yun Yen, Bingsen Zhou, Bret S E Heale, John J Rossi, Derek W Bartlett, Mark E Davis

Author Affiliations

1: Calando Pharmaceuticals, Inc., California Institute of Technology, Pasadena, California 91107, USA. jheidel@calandopharma.com

Associated clinical trials:

Safety Study of CALAA-01 to Treat Solid Tumor Cancers | NCT00689065

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