PubRank

Hermen S Overkleeft

Author PubWeight™ 21.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity. Diabetes 2007 2.01
2 Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2. J Biol Chem 2006 1.52
3 Consequences of a global enzyme shortage of agalsidase beta in adult Dutch Fabry patients. Orphanet J Rare Dis 2011 1.25
4 Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes. Nat Immunol 2010 1.24
5 Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells. J Biol Chem 2007 1.23
6 Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. J Biol Chem 2003 1.16
7 Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation. PLoS One 2009 1.08
8 Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities. Plant J 2009 1.01
9 The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation. Blood Cells Mol Dis 2010 0.99
10 Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. Plant Physiol 2012 0.99
11 Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment. Proc Natl Acad Sci U S A 2009 0.98
12 Proteasome activity imaging and profiling characterizes bacterial effector syringolin A. Plant Physiol 2010 0.90
13 Arg-Thz is a minimal substrate for the N(α),N(α)-arginyl methyltransferase involved in the biosynthesis of plantazolicin. Chem Commun (Camb) 2013 0.89
14 Glycosphingolipids and insulin resistance. Adv Exp Med Biol 2011 0.84
15 Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells. Mol Immunol 2008 0.83
16 The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains. Chem Biol 2012 0.83
17 Poly(ethylene glycol)-based stable isotope labeling reagents for the quantitative analysis of low molecular weight metabolites by LC-MS. Anal Chem 2008 0.81
18 Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule. Mol Immunol 2009 0.80
19 Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angew Chem Int Ed Engl 2009 0.80
20 From covalent glycosidase inhibitors to activity-based glycosidase probes. Chemistry 2014 0.78
21 Photochemical generation of six- and five-membered cyclic vinyl cations. J Org Chem 2006 0.75
22 Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides. J Pept Sci 2007 0.75
23 β-Rhamnosides from 6-thio mannosides. Chem Commun (Camb) 2012 0.75
24 Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model. Vaccine 2004 0.75