Dissecting the genetic contribution to coronary heart disease.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 1686444)

Published in Am J Hum Genet on December 01, 1991

Authors

J W MacCluer, C M Kammerer

Articles cited by this

A receptor-mediated pathway for cholesterol homeostasis. Science (1986) 19.28

High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med (1977) 15.39

A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol (1990) 7.24

Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis (1988) 6.01

Apolipoprotein genetic variation and human disease. Physiol Rev (1988) 3.29

Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA (1988) 3.04

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100. Proc Natl Acad Sci U S A (1989) 2.68

Risk factors for cardiovascular mortality in Mexican Americans and non-Hispanic whites. San Antonio Heart Study. Am J Epidemiol (1990) 2.03

Ischemic heart disease, atherosclerosis, and longevity. Circulation (1966) 2.03

Apolipoprotein E polymorphisms affect atherosclerosis in young males. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Arterioscler Thromb (1991) 1.58

Lp(a) lipoprotein and pre-beta1-lipoprotein in patients with coronary heart disease. Clin Genet (1974) 1.54

Apolipoprotein E isoform phenotyping methodology and population frequency with identification of apoE1 and apoE5 isoforms. J Lipid Res (1987) 1.49

Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. III. Identification of genetic effects using 12 polymorphic genetic blood marker systems. Am J Hum Genet (1976) 1.42

DNA polymorphisms of the apolipoprotein genes--their use in the investigation of the genetic component of hyperlipidaemia and atherosclerosis. Atherosclerosis (1988) 1.37

Familial combined hyperlipidaemia linked to the apolipoprotein AI-CII-AIV gene cluster on chromosome 11q23-q24. Nature (1991) 1.32

Genetic determination of plasma apolipoprotein AI in a population-based sample. Am J Hum Genet (1989) 1.29

The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances. Am J Hum Genet (1991) 1.25

DNA polymorphism and the study of disease associations. Hum Genet (1988) 1.24

Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. J Clin Invest (1989) 1.24

Pathophysiology of reverse cholesterol transport. Insights from inherited disorders of lipoprotein metabolism. Arteriosclerosis (1990) 1.22

Trends in CHD in the United States. Int J Epidemiol (1989) 1.18

The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipoprotein and triglyceride levels. Ann Hum Genet (1987) 1.16

Genetic analysis of apolipoprotein A-I in two dietary environments. Am J Hum Genet (1990) 1.15

Genetic studies of human apolipoproteins. IX. Apolipoprotein D polymorphism and its relation to serum lipoprotein lipid levels. Am J Hum Genet (1989) 1.12

Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high fat diet. Arteriosclerosis (1990) 1.08

Existence of consistent hypo- and hyperresponders to dietary cholesterol in man. Am J Epidemiol (1986) 1.06

The relationship of dietary cholesterol to serum cholesterol concentration and to atherosclerosis in man. Am J Clin Nutr (1979) 1.04

Genetic studies of human apolipoproteins. III. Polymorphism of apolipoprotein C-II. Hum Hered (1988) 0.99

Genetic studies of human apolipoproteins. XV. An overview of IEF immunoblotting methods to screen apolipoprotein polymorphisms. Hum Hered (1990) 0.94

Relationship between sensitivity to dietary fat and dietary cholesterol. Arteriosclerosis (1990) 0.93

Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change. Genet Epidemiol (1990) 0.93

Role of apolipoprotein E and B gene variation in determining response of lipid, lipoprotein, and apolipoprotein levels to increased dietary cholesterol. Am J Hum Genet (1991) 0.92

Major locus inheritance of apolipoprotein B in Utah pedigrees. Genet Epidemiol (1987) 0.91

Genetic mutations affecting human lipoprotein metabolism. Adv Hum Genet (1985) 0.89

Interaction between low density lipoprotein receptor (LDLR) and apolipoprotein E (apoE) alleles contributes to normal variation in lipid level. Clin Genet (1989) 0.86

Variability gene effect on cholesterol at the Kidd blood group locus. Clin Genet (1988) 0.84

"Variability gene" effect of cholesteryl ester transfer protein (CETP) genes. Clin Genet (1989) 0.84

Genetic factors influencing lipoprotein structure: implications for atherosclerosis. Lab Invest (1990) 0.79

Quantitative genetics: a critique. Soc Biol (1979) 0.79

Genetic studies of human apolipoproteins. XX. Genetic polymorphism of apolipoprotein J and its impact on quantitative lipid traits in normolipidemic subjects. Am J Hum Genet (1991) 0.78

Articles by these authors

Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation (1996) 4.10

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat Genet (1997) 3.37

Frequencies of consanguineous marriage and accumulation of inbreeding in an artifical population. Am J Hum Genet (1970) 1.65

Genetics of atherosclerosis risk factors in Mexican Americans. Nutr Rev (1999) 1.61

Some genetic programs to supplement self-instruction in FORTRAN. Am J Hum Genet (1967) 1.60

Is there an excess in maternal transmission of NIDDM? Diabetologia (1995) 1.50

Simulation of a common oligogenic disease with quantitative risk factors. GAW9 problem 2: the answers. Genet Epidemiol (1995) 1.39

Estimating the effective size of human populations. Am J Hum Genet (1970) 1.37

Comparison of two preliminary methods of quantitative linkage analysis. Hum Hered (1985) 1.33

Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arterioscler Thromb Vasc Biol (1996) 1.30

Association among 5-year changes in weight, physical activity, and cardiovascular disease risk factors in Mexican Americans. Am J Epidemiol (2000) 1.27

Genetic markers for ancestry are correlated with body composition traits in older African Americans. Osteoporos Int (2007) 1.27

Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study. Circulation (1995) 1.23

Genome-wide linkage analysis of blood pressure in Mexican Americans. Genet Epidemiol (2001) 1.23

Demographic structure of a primitive population: a simulation. Am J Phys Anthropol (1971) 1.23

Racial differences in the length of the human Y chromosome. Cytogenetics (1966) 1.19

A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor. Diabetes (1999) 1.16

Genetic analysis of apolipoprotein A-I in two dietary environments. Am J Hum Genet (1990) 1.15

A genome search identifies major quantitative trait loci on human chromosomes 3 and 4 that influence cholesterol concentrations in small LDL particles. Arterioscler Thromb Vasc Biol (1999) 1.12

Monte Carlo methods in human population genetics: a computer model incorporating age-specific birth and death rates. Am J Hum Genet (1967) 1.09

Human pedigree-based quantitative-trait-locus mapping: localization of two genes influencing HDL-cholesterol metabolism. Am J Hum Genet (1999) 1.08

Bone mineral density, carotid artery intimal medial thickness, and the vitamin D receptor BsmI polymorphism in Mexican American women. Calcif Tissue Int (2004) 1.08

Effects of NIDDM on lipoprotein(a) concentration and apolipoprotein(a) size. Diabetes (1994) 1.07

Association studies of vascular phenotypes: how and why? Arterioscler Thromb Vasc Biol (2002) 1.06

Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity. Diabetes Care (2001) 1.06

Pleiotropy and genotype by diet interaction in a baboon model for atherosclerosis: a multivariate quantitative genetic analysis of HDL subfractions in two dietary environments. Arterioscler Thromb Vasc Biol (1999) 1.05

Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene, POMC. J Clin Endocrinol Metab (1999) 1.05

Major gene with sex-specific effects influences fat mass in Mexican Americans. Genet Epidemiol (1995) 1.04

A major locus influencing plasma high-density lipoprotein cholesterol levels in the San Antonio Family Heart Study. Segregation and linkage analyses. Arterioscler Thromb Vasc Biol (1995) 1.04

Quantitative genetics of serum sex hormone-binding globulin levels in participants in the San Antonio Family Heart Study. Metabolism (1997) 1.03

Diabetes and hypertension in Mexican American families: relation to cardiovascular risk. Am J Epidemiol (1999) 1.03

A quantitative trait locus on chromosome 16q influences variation in plasma HDL-C levels in Mexican Americans. Arterioscler Thromb Vasc Biol (2003) 1.02

Sudden cardiac death, genes, and arrhythmogenesis : consideration of new population and mechanistic approaches from a national heart, lung, and blood institute workshop, part I. Circulation (2001) 1.01

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. Mol Psychiatry (2011) 1.01

Diabetes mellitus and impaired fasting glucose in Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. Diabetologia (2005) 1.01

Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study. J Lipid Res (2005) 0.99

NIDDM in Mexican-American families. Heterogeneity by age of onset. Diabetes Care (1994) 0.98

Genetic and environmental correlations among hormone levels and measures of body fat accumulation and topography. J Clin Endocrinol Metab (1996) 0.98

Simulated data for a complex genetic trait (problem 2 for GAW11): how the model was developed, and why. Genet Epidemiol (1999) 0.98

A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans. J Clin Invest (1998) 0.96

Multivariate genetic analysis of nevus measurements and melanoma. Cytogenet Cell Genet (1992) 0.95

Sudden cardiac death, genes, and arrhythmogenesis: consideration of new population and mechanistic approaches from a National Heart, Lung, and Blood Institute workshop, Part II. Circulation (2001) 0.93

Evidence for linkage of postchallenge insulin levels with intestinal fatty acid-binding protein (FABP2) in Mexican-Americans. Diabetes (1995) 0.92

Evidence for a major gene for type II diabetes and linkage analyses with selected candidate genes in Mexican-Americans. Diabetes (1996) 0.92

Segregation analysis of quantitative traits in nuclear families: comparison of three program packages. Genet Epidemiol (1989) 0.91

Genome-wide linkage analysis of pulse pressure in Mexican Americans. Hypertension (2001) 0.91

Characterization of the genetic elements controlling lipoprotein(a) concentrations in Mexican Americans. Evidence for at least three controlling elements linked to LPA, the locus encoding apolipoprotein(a). Atherosclerosis (1997) 0.91

Genetic Analysis Workshop 6: Linkage analysis based on affected pedigree members. Prog Clin Biol Res (1989) 0.90

Shared and unique genetic effects among seven HDL phenotypes. Arterioscler Thromb Vasc Biol (1997) 0.90

Evidence for joint action of genes on diabetes status and CVD risk factors in American Indians: the strong heart family study. Int J Obes Relat Metab Disord (2003) 0.89

Method for quantitating cholesterol in subfractions of serum lipoproteins separated by gradient gel electrophoresis. Biochem Genet (1988) 0.88

Identification of a new SCN5A mutation, D1840G, associated with the long QT syndrome. Mutations in brief no. 153. Online. Hum Mutat (1998) 0.88

On the probability of demonstrating differential fertility in genetic studies. Ann Hum Genet (1978) 0.88

Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men. Osteoporos Int (2010) 0.88

Genetic influences on bone loss in the San Antonio Family Osteoporosis study. Osteoporos Int (2008) 0.87

Empirical power of three preliminary methods for ordering loci. Am J Hum Genet (1988) 0.87

Effects of selection for serum cholesterol concentrations on serum lipid concentrations and body weight in baboons. Am J Med Genet (1984) 0.87

Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry. J Lipid Res (2010) 0.87

Linkage of serum insulin concentrations to chromosome 3p in Mexican Americans. Diabetes (2000) 0.87

Genetic and environmental correlations among skinfold measures. Int J Obes Relat Metab Disord (1994) 0.87

Association of a common G6PC2 variant with fasting plasma glucose levels in non-diabetic individuals. Ann Nutr Metab (2009) 0.86

Linkage mapping in Papio baboons: conservation of a syntenic group of six markers on human chromosome 1. Genomics (1995) 0.86

Exploring the HDL likelihood surface. Genet Epidemiol (1993) 0.86

Genes influencing variation in serum osteocalcin concentrations are linked to markers on chromosomes 16q and 20q. J Clin Endocrinol Metab (2000) 0.86

Evidence for heritability of biogenic amine levels in the cerebrospinal fluid of rhesus monkeys. Biol Psychiatry (1995) 0.86

Conservation of human chromosome 18 in baboons (Papio hamadryas): a linkage map of eight human microsatellites. Cytogenet Cell Genet (1996) 0.85

Mixed model segregation analysis of LDL-C concentration with genotype-covariate interaction. Genet Epidemiol (1991) 0.85

Genome-wide linkage scan for plasma high density lipoprotein cholesterol, apolipoprotein A-1 and triglyceride variation among American Indian populations: the Strong Heart Family Study. J Med Genet (2009) 0.84

Analysis of HLA and disease susceptibility: chromosome 6 genes and sex influence long-QT phenotype. Am J Hum Genet (1994) 0.84

Inhibitory and excitatory amino acid receptors, c-fos expression, and calcium-binding proteins in the brain of baboons (Papio hamadryas) that exhibit 'spontaneous' grand mal epilepsy. Epilepsy Res Suppl (1992) 0.84

Pedigree analysis of HDL cholesterol concentration in baboons on two diets. Am J Hum Genet (1988) 0.83

Evidence of genetic heterogeneity in the long QT syndrome. Science (1993) 0.83

Estimation of vital rates by means of Monte Carlo simulation. Demography (1973) 0.83

Linkage mapping and physical localization of the major histocompatibility complex region of the marsupial Monodelphis domestica. Cytogenet Genome Res (2006) 0.82

Consanguinity avoidance and genotype frequencies in human populations. Hum Biol (1978) 0.82

Identification of LDL receptor gene marker associated with altered levels of LDL cholesterol and apolipoprotein B in baboons. Arteriosclerosis (1990) 0.82

Dietary and genetic effects on LDL size measures in baboons. Arterioscler Thromb Vasc Biol (1996) 0.81

Cross-species replication of a resistin mRNA QTL, but not QTLs for circulating levels of resistin, in human and baboon. Heredity (Edinb) (2008) 0.81

Linkage of essential hypertension to the angiotensinogen locus in Mexican Americans. Hypertension (1997) 0.80

Severely reduced recombination in females of the South American marsupial Monodelphis domestica. Cytogenet Cell Genet (1992) 0.80

Two major loci control variation in beta-lipoprotein cholesterol and response to dietary fat and cholesterol in baboons. Arterioscler Thromb Vasc Biol (1998) 0.79

Relative influence of heritability, environment and genetics on serum sclerostin. Osteoporos Int (2013) 0.78

Gravidity and parity in postmenopausal American Indian women: the Strong Heart Study. Hum Biol (2000) 0.78

Baboon apolipoprotein A-IV. Identification of Lys76-->Glu that distinguishes two common isoforms and detection of length polymorphisms at the carboxyl terminus. J Biol Chem (1993) 0.78

Evidence for a major gene affecting postchallenge insulin levels in Mexican-Americans. Diabetes (1995) 0.78

An evaluation of three statistics of structured exploratory data analysis. Am J Hum Genet (1984) 0.77

Detecting genetic effects on lipoprotein phenotypes in baboons: a review of methods and preliminary findings. Genetica (1987) 0.77

Distribution of specific apolipoproteins determined by immunoblotting of baboon lipoproteins resolved by polyacrylamide gradient gel electrophoresis. Biochem Genet (1992) 0.77

Genetic differentiation associated with gait within American standardbred horses. Anim Genet (1987) 0.77