Published in Hum Hered on May 02, 2007
Family-based association studies for next-generation sequencing. Am J Hum Genet (2012) 1.65
Identifying modifier genes of monogenic disease: strategies and difficulties. Hum Genet (2008) 1.13
Finding genes underlying human disease. Clin Genet (2009) 1.07
The household contact study design for genetic epidemiological studies of infectious diseases. Front Genet (2013) 0.98
Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects. Eur J Hum Genet (2008) 0.98
Genomic approaches to coronary artery disease. Indian J Med Res (2010) 0.96
Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterization. Psychiatr Clin North Am (2010) 0.93
Haplotyping methods for pedigrees. Hum Hered (2009) 0.90
Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study. Atherosclerosis (2009) 0.90
Estimation of genotype relative risks from pedigree data by retrospective likelihoods. Genet Epidemiol (2010) 0.84
A powerful test of parent-of-origin effects for quantitative traits using haplotypes. PLoS One (2011) 0.84
Genetic region characterization (Gene RECQuest) - software to assist in identification and selection of candidate genes from genomic regions. BMC Res Notes (2009) 0.83
Combining genetic association study designs: a GWAS case study. Front Genet (2013) 0.83
Genotype-specific recurrence risks as indicators of the genetic architecture of complex diseases. Am J Hum Genet (2008) 0.82
Establishing a community partnership to optimize recruitment of African American pedigrees for a genetic epidemiology study. J Community Genet (2011) 0.82
PedWiz: a web-based tool for pedigree informatics. Front Genet (2013) 0.81
Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice. Metabolism (2012) 0.81
PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population. PLoS Comput Biol (2015) 0.79
Comparison of univariate and multivariate linkage analysis of traits related to hypertension. BMC Proc (2009) 0.78
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis. Eur J Hum Genet (2011) 0.78
Partitioning of copy-number genotypes in pedigrees. BMC Bioinformatics (2010) 0.78
Study designs and methods post genome-wide association studies. Hum Genet (2012) 0.77
A composite-likelihood approach for identifying polymorphisms that are potentially directly associated with disease. Eur J Hum Genet (2008) 0.76
The power and robustness of maximum LOD score statistics. Ann Hum Genet (2008) 0.76
Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs. BMC Genet (2010) 0.75
'Sifting the significance from the data' - the impact of high-throughput genomic technologies on human genetics and health care. Hum Genomics (2012) 0.75
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Optimal two-stage genotyping in population-based association studies. Genet Epidemiol (2003) 6.01
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
Estimation of the inbreeding coefficient through use of genomic data. Am J Hum Genet (2003) 4.01
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Improved power by use of a weighted score test for linkage disequilibrium mapping. Am J Hum Genet (2006) 3.36
Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered (2003) 3.33
Choosing an optimal method to combine P-values. Stat Med (2009) 3.15
The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol (2007) 3.01
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet (2003) 2.92
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet (2005) 2.80
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility. Arthritis Rheum (2005) 2.48
Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet (2004) 2.36
Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet (2004) 2.21
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. Am J Hum Genet (2008) 2.20
Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet (2005) 2.18
A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Stat Med (2006) 2.18
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (2006) 2.08
Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA. Science (2011) 2.04
Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am J Respir Crit Care Med (2004) 2.03
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. J Diabetes Complications (2005) 1.87
Self-reported race and genetic admixture. N Engl J Med (2006) 1.85
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A (2003) 1.84
The meaning of interaction. Hum Hered (2010) 1.83
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
A whole-genome scan for obstructive sleep apnea and obesity. Am J Hum Genet (2002) 1.81
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes (2007) 1.61
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet (2007) 1.55
Impact of parental relationships in maximum lod score affected sib-pair method. Genet Epidemiol (2002) 1.54
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet (2003) 1.53
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (2007) 1.44
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol (2002) 1.44
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol (2011) 1.43
Sampling correction in linkage analysis. Genet Epidemiol (2004) 1.43
Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One (2008) 1.41
Plasma aldosterone is independently associated with the metabolic syndrome. Hypertension (2006) 1.40
Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res (2009) 1.38
Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am J Hum Genet (2004) 1.36
Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. Hum Mol Genet (2005) 1.36
A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans. Am J Hum Genet (2006) 1.31
Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci (2008) 1.29
Statistical interaction in human genetics: how should we model it if we are looking for biological interaction? Nat Rev Genet (2010) 1.28
Two-level Haseman-Elston regression for general pedigree data analysis. Genet Epidemiol (2005) 1.28
Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma. Eur J Hum Genet (2005) 1.28
Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study. Proc Natl Acad Sci U S A (2004) 1.27
The power of independent types of genetic information to detect association in a case-control study design. Genet Epidemiol (2008) 1.24
Adaptive two-stage analysis of genetic association in case-control designs. Hum Hered (2007) 1.23
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt. Hypertension (2007) 1.23
Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis. Arthritis Res Ther (2006) 1.22
Single-marker and two-marker association tests for unphased case-control genotype data, with a power comparison. Genet Epidemiol (2010) 1.22
A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotyped. Genet Epidemiol (2009) 1.18
A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study. Sarcoidosis Vasc Diffuse Lung Dis (2005) 1.18
Two-marker association tests yield new disease associations for coronary artery disease and hypertension. Hum Genet (2011) 1.16
HLA related genetic risk for coeliac disease. Gut (2007) 1.16
Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m. Proc Natl Acad Sci U S A (2004) 1.16
Heritability analysis of cytokines as intermediate phenotypes of tuberculosis. J Infect Dis (2003) 1.16
Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Hum Hered (2003) 1.15
Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence. Biol Psychiatry (2008) 1.13
Heritability of renal function in hypertensive families of African descent in the Seychelles (Indian Ocean). Kidney Int (2005) 1.13
Detecting genetic interactions for quantitative traits with U-statistics. Genet Epidemiol (2011) 1.13
Identifying modifier genes of monogenic disease: strategies and difficulties. Hum Genet (2008) 1.13
The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity. Am J Hum Genet (2003) 1.11
Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. Am J Hum Genet (2008) 1.10
Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure. BMC Genet (2003) 1.10
In silico gene prioritization by integrating multiple data sources. PLoS One (2011) 1.10
GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks. AIDS (2004) 1.08
Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. Am J Nephrol (2011) 1.07
Haplotype-based quantitative trait mapping using a clustering algorithm. BMC Bioinformatics (2006) 1.07
Robust asymptotic sampling theory for correlations in pedigrees. Stat Med (2003) 1.07
Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis. Hum Hered (2005) 1.05
Association of vitamin D receptor gene variants, adiposity and colon cancer. Carcinogenesis (2008) 1.05
Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans. Biol Psychiatry (2006) 1.05
Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes. Hum Genet (2007) 1.04
Detection of susceptibility loci by genome-wide linkage analysis. BMC Genet (2005) 1.03
The distribution of long range admixture linkage disequilibrium in an African-American population. Hum Hered (2002) 1.03
Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes. Hum Mol Genet (2007) 1.03
A modified revisited Haseman-Elston method to further improve power. Hum Hered (2004) 1.02
A framework for structural equation models in general pedigrees. Hum Hered (2011) 1.02
Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases? Eur J Hum Genet (2006) 1.02
Structural equation model-based genome scan for the metabolic syndrome. BMC Genet (2003) 1.02
High heritability of ambulatory blood pressure in families of East African descent. Hypertension (2005) 1.02
A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology. Int J Epidemiol (2007) 1.01
Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs. Ann Hum Genet (2005) 1.01
A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. Genet Epidemiol (2012) 1.00
The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium. Am J Hum Genet (2006) 1.00
Identification of gene-gene interactions in the presence of missing data using the multifactor dimensionality reduction method. Genet Epidemiol (2009) 1.00
Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data. BMC Syst Biol (2012) 1.00
Evaluation of removable statistical interaction for binary traits. Stat Med (2012) 0.99
Distribution and magnitude of type I error of model-based multipoint lod scores: implications for multipoint mod scores. Genet Epidemiol (2006) 0.98
Nonparametric disequilibrium mapping of functional sites using haplotypes of multiple tightly linked single-nucleotide polymorphism markers. Genetics (2003) 0.97
Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genet Epidemiol (2006) 0.97
Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2. Hum Immunol (2008) 0.97
A non-parametric method for building predictive genetic tests on high-dimensional data. Hum Hered (2011) 0.96
A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer. Am J Epidemiol (2007) 0.96