Published in J Neurosci on May 09, 2007
Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci (2013) 3.53
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J (2008) 2.31
TRPC3 channels are required for synaptic transmission and motor coordination. Neuron (2008) 2.30
Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease. Dev Neurobiol (2010) 2.19
A simple role for BDNF in learning and memory? Front Mol Neurosci (2010) 1.68
Role of the brain-derived neurotrophic factor at glutamatergic synapses. Br J Pharmacol (2007) 1.64
The role of transient receptor potential cation channels in Ca2+ signaling. Cold Spring Harb Perspect Biol (2010) 1.56
BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses. Exp Brain Res (2009) 1.42
Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiol Dis (2009) 1.31
An ultra-short dopamine pathway regulates basal ganglia output. J Neurosci (2009) 1.23
Constitutively active TRPC3 channels regulate basal ganglia output neurons. J Neurosci (2008) 1.21
Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism. J Neurodev Disord (2009) 1.10
BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. J Neurophysiol (2007) 1.08
Brain-derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathway. J Physiol (2008) 1.08
The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media. J Neurosci Methods (2007) 1.06
Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons. J Neurophysiol (2010) 1.06
Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif (2008) 1.04
Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca²⁺ wave-dependent activation of SK and TRPC channels. J Physiol (2011) 1.01
Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB. Hippocampus (2008) 0.99
NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells. J Neurosci (2012) 0.98
Dendritic spine dysgenesis in Rett syndrome. Front Neuroanat (2014) 0.97
Intracellular Ca2+ stores and Ca2+ influx are both required for BDNF to rapidly increase quantal vesicular transmitter release. Neural Plast (2012) 0.96
Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. J Neurosci (2012) 0.95
Functional roles of TRPC channels in the developing brain. Pflugers Arch (2008) 0.93
Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice. Proc Natl Acad Sci U S A (2012) 0.93
Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels. Hippocampus (2012) 0.93
BDNF - a key transducer of antidepressant effects. Neuropharmacology (2015) 0.93
Intrinsic and integrative properties of substantia nigra pars reticulata neurons. Neuroscience (2011) 0.92
BDNF regulates the expression and distribution of vesicular glutamate transporters in cultured hippocampal neurons. PLoS One (2013) 0.91
EEA1 restores homeostatic synaptic plasticity in hippocampal neurons from Rett syndrome mice. J Physiol (2017) 0.91
Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission. J Biol Chem (2013) 0.90
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels. PLoS One (2013) 0.89
BDNF evokes release of endogenous cannabinoids at layer 2/3 inhibitory synapses in the neocortex. J Neurophysiol (2010) 0.88
TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain. Pflugers Arch (2014) 0.88
Homer regulates calcium signalling in growth cone turning. Neural Dev (2009) 0.87
Emerging roles of canonical TRP channels in neuronal function. Adv Exp Med Biol (2011) 0.87
Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation. Mol Cell Neurosci (2013) 0.86
TRPM2 channels are required for NMDA-induced burst firing and contribute to H(2)O(2)-dependent modulation in substantia nigra pars reticulata GABAergic neurons. J Neurosci (2013) 0.86
A role of canonical transient receptor potential 5 channel in neuronal differentiation from A2B5 neural progenitor cells. PLoS One (2010) 0.85
Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness. Int J Nanomedicine (2015) 0.84
Brain-derived neurotrophic factor (BDNF) induces sustained intracellular Ca2+ elevation through the up-regulation of surface transient receptor potential 3 (TRPC3) channels in rodent microglia. J Biol Chem (2014) 0.83
HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons. Hippocampus (2011) 0.83
The puzzling role of TRPC3 channels in motor coordination. Pflugers Arch (2009) 0.83
Leptin-induced spine formation requires TrpC channels and the CaM kinase cascade in the hippocampus. J Neurosci (2014) 0.82
Postsynaptic TRPC1 function contributes to BDNF-induced synaptic potentiation at the developing neuromuscular junction. J Neurosci (2011) 0.82
Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels. PLoS One (2010) 0.82
Physiological Function and Characterization of TRPCs in Neurons. Cells (2014) 0.80
The role of canonical transient receptor potential channels in seizure and excitotoxicity. Cells (2014) 0.80
Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels. J Cell Biol (2015) 0.79
Differential regulation of TRPC4 in the vasopressin magnocellular system by water deprivation and hepatic cirrhosis in the rat. Am J Physiol Regul Integr Comp Physiol (2013) 0.78
Mechanism of earthquake simulation as a prenatal stressor retarding rat offspring development and chinese medicine correcting the retardation: hormones and gene-expression alteration. Evid Based Complement Alternat Med (2012) 0.77
Microglial Intracellular Ca(2+) Signaling in Synaptic Development and its Alterations in Neurodevelopmental Disorders. Front Cell Neurosci (2017) 0.75
Mechanisms of BDNF regulation in asthmatic airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice. Epilepsia (2016) 0.75
Calcium-Dependent and Synapsin-Dependent Pathways for the Presynaptic Actions of BDNF. Front Cell Neurosci (2017) 0.75
A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice. Dis Model Mech (2017) 0.75
The BDNF val-66-met Polymorphism Affects Neuronal Morphology and Synaptic Transmission in Cultured Hippocampal Neurons from Rett Syndrome Mice. Front Cell Neurosci (2017) 0.75
TRPC3 channel mediates excitation of striatal cholinergic interneurons. Neurol Sci (2014) 0.75
Pre-synaptic TrkB in basolateral amygdala neurons mediates BDNF signaling transmission in memory extinction. Cell Death Dis (2017) 0.75
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem (1994) 14.36
A simple method for organotypic cultures of nervous tissue. J Neurosci Methods (1991) 14.18
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proc Natl Acad Sci U S A (1990) 13.34
TRP channels as cellular sensors. Nature (2003) 12.03
Neurotrophins as synaptic modulators. Nat Rev Neurosci (2001) 7.08
Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu Rev Neurosci (2001) 6.36
Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature (1996) 4.41
Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol (2004) 4.19
The TRP channels, a remarkably functional family. Cell (2002) 4.06
BDNF and activity-dependent synaptic modulation. Learn Mem (2003) 4.04
Neurotrophins and synaptic plasticity. Annu Rev Neurosci (1999) 4.01
SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J (1990) 3.86
TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron (2001) 3.74
Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J Pharmacol Exp Ther (1990) 3.55
Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron (1997) 3.27
Organotypic monolayer cultures of nervous tissue. J Neurosci Methods (1981) 3.19
Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11
The Trk family of neurotrophin receptors. J Neurobiol (1994) 3.06
CREB: a major mediator of neuronal neurotrophin responses. Neuron (1997) 3.04
Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron (1997) 3.03
Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci (1996) 2.98
Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin. J Biol Chem (1988) 2.97
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem (2002) 2.79
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci (2001) 2.51
Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9. Nature (2002) 2.49
Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron (1997) 2.47
On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. Proc Natl Acad Sci U S A (1996) 2.44
Cellular mechanisms regulating activity-dependent release of native brain-derived neurotrophic factor from hippocampal neurons. J Neurosci (2002) 2.33
Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry. J Biol Chem (1998) 2.32
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature (2003) 2.31
Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons. Proc Natl Acad Sci U S A (2002) 2.23
Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron (1999) 2.15
Neurotrophin secretion: current facts and future prospects. Prog Neurobiol (2003) 2.12
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. Learn Mem (2004) 1.99
Modulation of the Ras/Raf/MEK/ERK pathway by Ca(2+), and calmodulin. Cell Signal (2002) 1.95
Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J Neurosci (1998) 1.91
Neuronal transfection in brain slices using particle-mediated gene transfer. Neuron (1994) 1.87
Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins. J Neurosci (1995) 1.85
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation. J Neurosci (1999) 1.74
Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones. J Physiol (2003) 1.67
K-252 compounds: modulators of neurotrophin signal transduction. J Neurochem (1992) 1.49
VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx. Mol Cell (2004) 1.49
Exocytotic insertion of TRPC6 channel into the plasma membrane upon Gq protein-coupled receptor activation. J Biol Chem (2003) 1.45
Dissociation of regulated trafficking of TRPC3 channels to the plasma membrane from their activation by phospholipase C. J Biol Chem (2006) 1.39
Muscarinic activation of a voltage-dependent cation nonselective current in rat association cortex. J Neurosci (1996) 1.36
BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones. Neuroreport (1993) 1.34
Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices. J Neurophysiol (1999) 1.29
BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses. J Physiol (2006) 1.26
A long-lasting calcium-activated nonselective cationic current is generated by synaptic stimulation or exogenous activation of group I metabotropic glutamate receptors in CA1 pyramidal neurons. J Neurosci (1997) 1.25
The InsP3 receptor and intracellular Ca2+ signaling. Curr Opin Neurobiol (1997) 1.20
Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons. Eur J Neurosci (2003) 1.19
Group I metabotropic glutamate receptors activate a calcium-sensitive transient receptor potential-like conductance in rat hippocampus. J Physiol (2003) 1.19
Neural connections between the lateral geniculate nucleus and visual cortex in vitro. Science (1989) 1.18
The role of neurotrophins in neurotransmitter release. Neuroscientist (2002) 1.17
Capacitative calcium entry in the nervous system. Cell Calcium (2003) 1.15
Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons. Proc Natl Acad Sci U S A (1999) 1.15
Differential vesicular targeting and time course of synaptic secretion of the mammalian neurotrophins. J Neurosci (2005) 1.10
Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacol Ther (2006) 1.03
G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurons in hippocampal slices. J Neurosci (1995) 0.99
Molecular cloning and characterization of rat trp homologues from brain. Brain Res Mol Brain Res (1999) 0.98
Synaptic activation of transient receptor potential channels by metabotropic glutamate receptors in the lateral amygdala. Neuroscience (2005) 0.98
A novel voltage-dependent cation current in rat neocortical neurones. J Physiol (1994) 0.97
Both mGluR1 and mGluR5 mediate Ca2+ release and inward currents in hippocampal CA1 pyramidal neurons. Neuropharmacology (2004) 0.95
Optical imaging of cytosolic calcium, electrophysiology, and ultrastructure in pyramidal neurons of organotypic slice cultures from rat hippocampus. Neuroimage (1993) 0.95
Transient receptor potential-like channels mediate metabotropic glutamate receptor EPSCs in rat dopamine neurones. J Physiol (2004) 0.90
BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons. Brain Res (2006) 0.85
Calcium from internal stores modifies dendritic spine shape. Proc Natl Acad Sci U S A (1999) 0.82
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. Learn Mem (2004) 1.99
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci (2005) 1.68
Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones. J Physiol (2003) 1.67
Preclinical research in Rett syndrome: setting the foundation for translational success. Dis Model Mech (2012) 1.66
Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations. Neurobiol Dis (2009) 1.66
Network hyperexcitability in hippocampal slices from Mecp2 mutant mice revealed by voltage-sensitive dye imaging. J Neurophysiol (2011) 1.33
Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiol Dis (2009) 1.31
Kainate modulates presynaptic GABA release from two vesicle pools. J Neurosci (2008) 1.29
Experimental models of Rett syndrome based on Mecp2 dysfunction. Exp Biol Med (Maywood) (2011) 1.27
BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses. J Physiol (2006) 1.26
Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function. Hum Mol Genet (2013) 1.15
Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism. J Neurodev Disord (2009) 1.10
BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. J Neurophysiol (2007) 1.08
The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media. J Neurosci Methods (2007) 1.06
Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons. J Neurophysiol (2010) 1.06
Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacol Ther (2006) 1.03
Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice. Hippocampus (2014) 1.02
BDNF deregulation in Rett syndrome. Neuropharmacology (2013) 1.02
Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nat Neurosci (2007) 0.99
Intracellular Ca2+ stores and Ca2+ influx are both required for BDNF to rapidly increase quantal vesicular transmitter release. Neural Plast (2012) 0.96
Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels. Hippocampus (2012) 0.93
Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice. Proc Natl Acad Sci U S A (2012) 0.93
Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels. Free Radic Biol Med (2010) 0.91
Hippocampal CA1 pyramidal neurons of Mecp2 mutant mice show a dendritic spine phenotype only in the presymptomatic stage. Neural Plast (2012) 0.90
Divergent roles of p75NTR and Trk receptors in BDNF's effects on dendritic spine density and morphology. Neural Plast (2012) 0.87
MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons. PLoS One (2013) 0.87
The neuronal Arf GAP centaurin alpha1 modulates dendritic differentiation. J Cell Sci (2007) 0.87
GABA vesicles at synapses: are there 2 distinct pools? Neuroscientist (2009) 0.86
HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons. Hippocampus (2011) 0.83
Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue Mice. Autism Open Access (2012) 0.81
A novel DNA-binding feature of MeCP2 contributes to Rett syndrome. Front Cell Neurosci (2013) 0.80
Evaluation of current pharmacological treatment options in the management of Rett syndrome: from the present to future therapeutic alternatives. Curr Clin Pharmacol (2013) 0.80
Multiple approaches to investigate the transport and activity-dependent release of BDNF and their application in neurogenetic disorders. Neural Plast (2012) 0.79
The dynamics of excitatory synapse formation on dendritic spines. Cellscience (2009) 0.79
The effect of Rho-associated kinase inhibition on the ocular penetration of timolol maleate. Invest Ophthalmol Vis Sci (2013) 0.77