Published in J Biol Chem on February 10, 1976
Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients. Ann Surg (1988) 1.44
Regulation of protein turnover in skeletal and cardiac muscle. Biochem J (1991) 1.11
Adrenergic inhibition of branched-chain 2-oxo acid dehydrogenase in rat diaphragm muscle in vitro. Biochem J (1983) 1.11
Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway. J Clin Invest (1995) 1.09
Role of counterregulatory hormones in the catabolic response to stress. J Clin Invest (1984) 1.06
Effects of parathyroid hormone on skeletal muscle protein and amino acid metabolism in the rat. J Clin Invest (1983) 0.99
Skeletal muscle protein and amino acid metabolism in experimental chronic uremia in the rat: accelerated alanine and glutamine formation and release. J Clin Invest (1978) 0.98
Evidence that the hypertrophic action of clenbuterol on denervated rat muscle is not propranolol-sensitive. Br J Pharmacol (1989) 0.95
The action of the beta-agonist clenbuterol on protein metabolism in innervated and denervated phasic muscles. Biochem J (1989) 0.93
Regulation of proline oxidase activity by lactate. Proc Natl Acad Sci U S A (1977) 0.92
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis. Biochem J (1984) 0.91
Amino acid oxidation and alanine production in rat hemidiaphragm in vitro. Effects of dichloroacetate. Biochem J (1984) 0.89
The regulation of skeletal muscle alanine and glutamine formation and release in experimental chronic uremia in the rat: subsensitivity of adenylate cyclase and amino acid release to epinephrine and serotonin. J Clin Invest (1978) 0.87
The metabolic and endocrine effects of circulating catecholamines in fetal sheep. J Physiol (1978) 0.85
Early hormonal changes affect the catabolic response to trauma. Ann Surg (1993) 0.85
Effects of hyperthyroidism and hypothyroidism on glutamine metabolism by skeletal muscle of the rat. Biochem J (1990) 0.83
Glycolytic origin of alanine formed in rat diaphragm muscle in vitro. Biochem J (1985) 0.78
The impact of streptozotocin-induced diabetes mellitus on cyclic nucleotide regulation of skeletal muscle amino acid metabolism in the rat. J Clin Invest (1980) 0.78
Elevation of plasma epinephrine concentrations inhibits proteolysis and leucine oxidation in man via beta-adrenergic mechanisms. J Clin Invest (1989) 0.77
Nutrient interactions with reference to amino acid and protein metabolism in non-ruminants; particular emphasis on protein-energy relations in man. Z Ernahrungswiss (1991) 0.76
Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides. J Biol Chem (1972) 8.24
Radioimmunoassay for the measurement of adenosine 3',5'-cyclic phosphate. Proc Natl Acad Sci U S A (1969) 7.81
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med (1999) 7.24
Hormone-fuel interrelationships during fasting. J Clin Invest (1966) 6.44
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol (2001) 4.49
Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic sujbjects. J Clin Invest (1967) 3.60
Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat Immunol (2000) 3.58
Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc Natl Acad Sci U S A (1999) 3.35
Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell-deficient mice. Crit Care Med (1997) 2.97
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J Immunol (1999) 2.92
Growth hormone secretion during sleep. J Clin Invest (1968) 2.90
Radioimmunoassay for cyclic nucleotides. II. Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in mammalian tissues and body fluids. J Biol Chem (1972) 2.84
Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects. Diabetes (1966) 2.71
A failed assay opened a new door in growth hormone research. Endocrinology (1992) 2.69
An adrenergic receptor mechanism for the control of cyclic 3'5' adenosine monophosphate synthesis in tissues. Biochem Biophys Res Commun (1967) 2.55
Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes Obes Metab (2009) 2.23
Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis. JAMA (1992) 2.19
Nitric oxide inhibits stress-induced endothelial cell apoptosis. Crit Care Med (1998) 2.02
Measurement of "true" glucose production rates in infancy and childhood with 6,6-dideuteroglucose. Diabetes (1977) 2.02
Stimulation of insulin secretion by theophylline. Nature (1967) 1.89
Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release. J Biol Chem (1976) 1.87
Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock. Crit Care Med (2000) 1.85
Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids. J Clin Invest (1965) 1.83
The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum. Biochem Biophys Res Commun (1970) 1.72
Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway. Shock (1997) 1.71
Closed-loop and open-loop devices for blood glucose control in normal and diabetic subjects. Diabetes (1979) 1.69
The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man. J Clin Invest (1976) 1.63
Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis. J Biol Chem (1976) 1.59
The effect of fasting, diet, and actinomycin D on insulin secretion in the rat. J Clin Invest (1970) 1.55
Insulin biosynthesis. I. On the mechanism of glucose stimulation. J Biol Chem (1972) 1.54
Role of Na+ and K+ on sugar (2-deoxyglucose) and amino acid (alpha-aminoisobutyric acid) transport in striated muscle. Fed Proc (1966) 1.51
Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Crit Care Med (2000) 1.48
Inhibition of NO synthesis in septic shock. Lancet (1992) 1.46
Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis. Am J Clin Nutr (1972) 1.43
Clinical, biochemical, and neuropathologic findings following transplantation of adrenal medulla to the caudate nucleus for treatment of Parkinson's disease. Neurology (1989) 1.43
Dissociation of effects of insulin and contraction on glucose transport in rat epitrochlearis muscle. Am J Physiol (1985) 1.42
In-vivo measurement of glucose and alanine metabolism with stable isotopic tracers. Diabetes (1977) 1.41
Effect of glucocorticoids on plasma insulin. N Engl J Med (1966) 1.39
Hepatic ketogenesis and gluconeogenesis in humans. J Clin Invest (1974) 1.37
A new assay for adenosine 3',5'-cyclic monophosphate in tissue. Biochemistry (1967) 1.35
Propranolol does not prevent thyroid storm. N Engl J Med (1977) 1.33
Hypoalaninemia: a concomitant of ketotic hypoglycemia. J Clin Invest (1972) 1.33
Epitrochlearis muscle. I. Mechanical performance, energetics, and fiber composition. Am J Physiol (1980) 1.32
A microfluorometric enzymatic assay for the determination of alanine and pyruvate in plasma and tissues. J Lab Clin Med (1972) 1.32
Juvenile diabetes mellitus, a deficiency in insulin. Diabetes (1968) 1.31
A sensitive method for measuring polymerized and depolymerized forms of tubulin in tissues. J Cell Biol (1977) 1.30
Radioimmunoassay for the measurement of cyclic nucleotides. Adv Cyclic Nucleotide Res (1972) 1.29
Microtubule assembly and the intracellular transport of secretory granules in pancreatic islets. Science (1976) 1.28
Hypoglycemia in infancy and childhood. II. J Pediatr (1973) 1.28
Role of arginine in health and in renal disease. Am J Physiol (1994) 1.26
Hypoglycemia in infancy and childhood. I. J Pediatr (1973) 1.24
Hypoglycemia in compensated chronic renal insufficiency. Substrate limitation of gluconeogenesis. Diabetes (1974) 1.21
Muscle actin filaments bind pituitary secretory granules in vitro. J Cell Biol (1977) 1.21
Alanine and glutamine synthesis and release from skeletal muscle. III. Dietary and hormonal regulation. J Biol Chem (1976) 1.19
The regulation of gluconeogenesis in mammalian liver. The role of mitochondrial phosphoenolpyruvate carboxykinase. J Biol Chem (1973) 1.17
The interrelationships of the various pathways forming gluconeogenic precursors in guinea pig liver mitochondria. J Biol Chem (1971) 1.16
D-chiro-inositol metabolism in diabetes mellitus. Proc Natl Acad Sci U S A (1993) 1.15
Correlative studies of growth hormone and insulin plasma concentrations with metabolic abnormalities in acromegaly. J Lab Clin Med (1965) 1.15
Effect of diet composition on the hyperinsulinemia of obesity. N Engl J Med (1971) 1.14
Uncontrolled diabetes mellitus and hyperglucagonemia associated with an islet cell carcinoma. Am J Med (1975) 1.14
Increased gluconeogenic substrates in the small-for-gestational-age infant. N Engl J Med (1974) 1.14
Myosins of secretory tissues. J Cell Biol (1978) 1.12
Role of apoptosis in Pseudomonas aeruginosa pneumonia. Science (2001) 1.11
Ketotic hypoglycemia: an amino acid substrate limited disorder. J Clin Endocrinol Metab (1974) 1.08
Secretion of various endocrine substances by ACTH-secreting tumors--gastrin, melanotropin, norepinephrine, serotonin, parathormone, vasopressin, glucagon. Cancer (1968) 1.08
Insulin and glucagon secretion from rat islets maintained in a tissue culture-perifusion system. Diabetes (1979) 1.07
Nucleotide inhibition of adenyl cyclase activity in fat cell membranes. Biochim Biophys Acta (1969) 1.05
Binding of colchicine to purified microtubule protein. J Biol Chem (1975) 1.04
Increased intracellular Ca2+: a critical link in the pathophysiology of sepsis? Proc Natl Acad Sci U S A (1993) 1.04
Inducible nitric oxide synthase (iNOS) gene deficiency increases the mortality of sepsis in mice. Surgery (1999) 1.04
Physiological regulation of total tubulin and polymerized tubulin in tissues. J Cell Biol (1977) 1.03
Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats. Biochem Biophys Res Commun (2002) 1.03
The alpha-keto acids of branched-chain amino acids: simplified derivatization for physiological samples and complete separation as quinoxalinols by packed column gas chromatography. Anal Biochem (1980) 1.03
Sulfonamide-induced hypoglycemia in chronic renal failure. Arch Intern Med (1983) 1.03
Quantitative analysis of regenerating and degenerating areas within the lobule of the carbon tetrachloride-injured liver. Arch Biochem Biophys (1965) 1.02
Glutamine and glutamate metabolism in normal and diabetic subjects. Diabetes (1973) 1.02
Effect of short-chain fatty acids on plasma insulin in ruminant and nonruminant species. Endocrinology (1968) 1.02
Effect of insulin degludec versus sitagliptin in patients with type 2 diabetes uncontrolled on oral antidiabetic agents. Diabetes Obes Metab (2013) 1.02
Radioimmunoassay of beta lipoprotein-protein of rat serum. J Clin Invest (1969) 1.01
Effects of fatty acids on carbohydrate and fatty acid metabolism of rat diaphragm. Am J Physiol (1968) 1.01
Cytokine blockade in sepsis--Are two better than one? Crit Care Med (2001) 0.99
Effects of parathyroid hormone on skeletal muscle protein and amino acid metabolism in the rat. J Clin Invest (1983) 0.99
Dantrolene ameliorates the metabolic hallmarks of sepsis in rats and improves survival in a mouse model of endotoxemia. Proc Natl Acad Sci U S A (1994) 0.98
Hypothalamic stimulation of growth hormone and thyrotropin lease in vitro and pituitary 3'5'-adenosine cyclic monophosphate. Endocrinology (1970) 0.98
Regulation of intracellular sodium concentrations in rat diaphragm muscle. Science (1967) 0.98
Skeletal muscle protein and amino acid metabolism in experimental chronic uremia in the rat: accelerated alanine and glutamine formation and release. J Clin Invest (1978) 0.98
Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazole. Am J Physiol (1991) 0.96