Published in Antioxid Redox Signal on July 01, 2007
Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med (2010) 5.76
TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl) (2012) 1.52
Ceramide-rich platforms in transmembrane signaling. FEBS Lett (2010) 1.46
Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood (2010) 1.44
Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol (2007) 1.29
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension (2008) 1.23
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol (2008) 1.17
Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.16
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells. Kidney Int (2010) 1.12
Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. Free Radic Biol Med (2010) 1.12
Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology. Cardiovasc Res (2009) 1.12
Lipid raft redox signaling: molecular mechanisms in health and disease. Antioxid Redox Signal (2011) 1.06
Lipid rafts and caveolae and their role in compartmentation of redox signaling. Antioxid Redox Signal (2009) 1.02
Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res (2010) 1.01
Formation and function of ceramide-enriched membrane platforms with CD38 during M1-receptor stimulation in bovine coronary arterial myocytes. Am J Physiol Heart Circ Physiol (2008) 0.98
Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells. Antioxid Redox Signal (2010) 0.96
Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells. J Cell Sci (2012) 0.95
Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells. Biochim Biophys Acta (2010) 0.94
Membrane signaling induced by high doses of ionizing radiation in the endothelial compartment. Relevance in radiation toxicity. Int J Mol Sci (2013) 0.93
Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. Am J Physiol Heart Circ Physiol (2010) 0.93
Involvement of ceramide in cell death responses in the pulmonary circulation. Proc Am Thorac Soc (2011) 0.91
Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons. Front Physiol (2014) 0.91
Formation of lipid raft redox signalling platforms in glomerular endothelial cells: an early event of homocysteine-induced glomerular injury. J Cell Mol Med (2009) 0.91
Attenuation by statins of membrane raft-redox signaling in coronary arterial endothelium. J Pharmacol Exp Ther (2013) 0.90
Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells. Mol Biol Cell (2012) 0.90
Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand. Cell Transplant (2012) 0.87
Coronary endothelial dysfunction induced by nucleotide oligomerization domain-like receptor protein with pyrin domain containing 3 inflammasome activation during hypercholesterolemia: beyond inflammation. Antioxid Redox Signal (2015) 0.83
SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary arterial endothelium. Am J Physiol Heart Circ Physiol (2011) 0.81
Lysosome-membrane fusion mediated superoxide production in hyperglycaemia-induced endothelial dysfunction. PLoS One (2012) 0.81
Cross talk between ceramide and redox signaling: implications for endothelial dysfunction and renal disease. Handb Exp Pharmacol (2013) 0.81
Membrane raft redox signalosomes in endothelial cells. Free Radic Res (2010) 0.81
Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis. Oncotarget (2014) 0.78
Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction. J Mol Med (Berl) (2016) 0.77
Endogenous ceramide contributes to the transcytosis of oxLDL across endothelial cells and promotes its subendothelial retention in vascular wall. Oxid Med Cell Longev (2014) 0.76
Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects. Antioxid Redox Signal (2016) 0.75
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat Med (2004) 2.66
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet (2004) 2.66
Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells. Hypertension (2005) 2.62
Design and syntheses of novel N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide as inhibitors of cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase. Bioorg Med Chem (2013) 2.43
Ceramide-enriched membrane domains. Biochim Biophys Acta (2005) 2.25
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14
The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering. J Biol Chem (2005) 1.96
Role of renal medullary heme oxygenase in the regulation of pressure natriuresis and arterial blood pressure. Hypertension (2006) 1.92
Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. PLoS One (2011) 1.86
Mapping a novel locus for familial atrial fibrillation on chromosome 10p11-q21. Heart Rhythm (2006) 1.69
NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney Int (2013) 1.61
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats. J Biol Chem (2007) 1.60
Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis. J Mol Med (Berl) (2014) 1.59
Adiponectin increases macrophages cholesterol efflux and suppresses foam cell formation in patients with type 2 diabetes mellitus. Atherosclerosis (2013) 1.54
Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function. Circulation (2002) 1.54
Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene (2003) 1.53
Anthocyanin supplementation improves serum LDL- and HDL-cholesterol concentrations associated with the inhibition of cholesteryl ester transfer protein in dyslipidemic subjects. Am J Clin Nutr (2009) 1.53
TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl) (2012) 1.52
CD95 rapidly clusters in cells of diverse origins. Cancer Biol Ther (2003) 1.50
Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine. J Nutr (2008) 1.50
Ceramide-enriched membrane domains--structure and function. Biochim Biophys Acta (2008) 1.49
Biological aspects of ceramide-enriched membrane domains. Prog Lipid Res (2007) 1.40
Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. Kidney Int (2004) 1.39
Production of NAADP and its role in Ca2+ mobilization associated with lysosomes in coronary arterial myocytes. Am J Physiol Heart Circ Physiol (2006) 1.34
Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys. Am J Physiol Renal Physiol (2006) 1.33
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal (2012) 1.32
Cell volume regulatory ion channels in cell proliferation and cell death. Methods Enzymol (2007) 1.31
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension (2012) 1.31
Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30
Reactive oxygen species limit neutrophil life span by activating death receptor signaling. Blood (2004) 1.30
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem (2010) 1.29
Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol (2007) 1.29
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes. J Cell Mol Med (2008) 1.28
Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms. J Biol Chem (2005) 1.28
Salt-sensitive hypertension induced by decoy of transcription factor hypoxia-inducible factor-1alpha in the renal medulla. Circ Res (2008) 1.27
A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26
Ceramide-rich membrane rafts mediate CD40 clustering. J Immunol (2002) 1.24
Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing miRNA-10b. Circ Res (2012) 1.24
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension (2008) 1.23
Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease. Cell Microbiol (2008) 1.22
Lipid raft redox signaling platforms in endothelial dysfunction. Antioxid Redox Signal (2007) 1.22
Ceramide-induced activation of NADPH oxidase and endothelial dysfunction in small coronary arteries. Am J Physiol Heart Circ Physiol (2002) 1.22
(4Z)-4-[(4-Chloro-anilino)(phen-yl)methyl-ene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one. Acta Crystallogr Sect E Struct Rep Online (2009) 1.22
Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Res (2009) 1.21
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20
Role of ceramide in TNF-alpha-induced impairment of endothelium-dependent vasorelaxation in coronary arteries. Am J Physiol Heart Circ Physiol (2002) 1.20
MALAT-1 interacts with hnRNP C in cell cycle regulation. FEBS Lett (2013) 1.19
Mechanisms of homocysteine-induced glomerular injury and sclerosis. Am J Nephrol (2007) 1.19
Autocrine/paracrine pattern of superoxide production through NAD(P)H oxidase in coronary arterial myocytes. Am J Physiol Heart Circ Physiol (2006) 1.17
Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection. J Immunol (2010) 1.17
Sphingolipids in the lungs. Am J Respir Crit Care Med (2008) 1.17
Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.16
Regulation of NADPH oxidase activity is associated with miRNA-25-mediated NOX4 expression in experimental diabetic nephropathy. Am J Nephrol (2010) 1.14
Ceramide: physiological and pathophysiological aspects. Arch Biochem Biophys (2007) 1.14
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. J Med Chem (2007) 1.13
Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis. Am J Respir Cell Mol Biol (2009) 1.13
Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats. Am J Nephrol (2007) 1.12
Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. Free Radic Biol Med (2010) 1.12
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells. Kidney Int (2010) 1.12
Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy. Biochim Biophys Acta (2010) 1.12
Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytes. Biochim Biophys Acta (2009) 1.12
Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. J Pharmacol Exp Ther (2010) 1.12
Alveolar inflammation in cystic fibrosis. J Cyst Fibros (2010) 1.11
Cyanidin 3-glucoside attenuates obesity-associated insulin resistance and hepatic steatosis in high-fat diet-fed and db/db mice via the transcription factor FoxO1. J Nutr Biochem (2011) 1.11
Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle. Am J Physiol Heart Circ Physiol (2002) 1.11
Eryptosis, a window to systemic disease. Cell Physiol Biochem (2008) 1.10
An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E-deficient mice. J Nutr (2006) 1.10
Activation of NAD(P)H oxidase by outward movements of H+ ions in renal medullary thick ascending limb of Henle. Am J Physiol Renal Physiol (2005) 1.09
Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. Cell Physiol Biochem (2013) 1.08
3-Mesityl-2-oxo-1-oxaspiro-[4.4]non-3-en-4-yl 4-chloro-benzoate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.08
Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells. Cancer Res (2007) 1.07
NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury. Cell Physiol Biochem (2009) 1.07
Ceramide-induced cell death in malignant cells. Cancer Lett (2008) 1.07
14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. Am J Physiol Heart Circ Physiol (2002) 1.07
Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms. Biochem Biophys Res Commun (2003) 1.07
Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector? Antioxid Redox Signal (2015) 1.07