Published in Biochem J on August 01, 2007
JNK signaling in apoptosis. Oncogene (2008) 4.72
Cisplatin in cancer therapy: molecular mechanisms of action. Eur J Pharmacol (2014) 2.73
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med (2009) 2.03
Cellular responses to Cisplatin-induced DNA damage. J Nucleic Acids (2010) 1.82
A gene signature-based approach identifies mTOR as a regulator of p73. Mol Cell Biol (2008) 1.34
Therapeutic prospects for p73 and p63: rising from the shadow of p53. Drug Resist Updat (2008) 1.32
p73 as a pharmaceutical target for cancer therapy. Curr Pharm Des (2011) 0.90
Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation. Proc Natl Acad Sci U S A (2009) 0.89
miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4-JNK pathway. Apoptosis (2014) 0.84
α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73. Breast Cancer Res (2011) 0.84
AMPK couples p73 with p53 in cell fate decision. Cell Death Differ (2014) 0.83
Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α. PLoS Pathog (2013) 0.83
TAp73-mediated the activation of c-Jun N-terminal kinase enhances cellular chemosensitivity to cisplatin in ovarian cancer cells. PLoS One (2012) 0.83
A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression. Oncogene (2014) 0.83
JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships. Microbiol Mol Biol Rev (2016) 0.81
TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function. J Biol Chem (2013) 0.81
p73-Binding Partners and Their Functional Significance. Int J Proteomics (2011) 0.78
Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome. Sci Rep (2016) 0.78
STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death. J Biomed Sci (2012) 0.77
A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. Oncotarget (2011) 0.77
Preclinical Assessment of Low Doses of Cisplatin in the Management of Acute Promyelocytic Leukemia. Int J Cancer Res Mol Mech (2015) 0.76
Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifs. Int J Mol Sci (2014) 0.75
Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies. Biomolecules (2017) 0.75
Signal transduction by the JNK group of MAP kinases. Cell (2000) 18.24
Live or let die: the cell's response to p53. Nat Rev Cancer (2002) 15.06
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev (2001) 13.15
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A (2001) 11.06
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (2000) 8.56
The specificities of protein kinase inhibitors: an update. Biochem J (2003) 7.76
Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer (2004) 6.67
p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature (1997) 5.42
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature (1999) 5.33
A mammalian scaffold complex that selectively mediates MAP kinase activation. Science (1998) 4.78
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature (2002) 4.56
Chemosensitivity linked to p73 function. Cancer Cell (2003) 3.63
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature (1999) 3.55
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature (1999) 3.50
p73: Friend or foe in tumorigenesis. Nat Rev Cancer (2002) 3.30
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J Biol Chem (2003) 2.69
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell (2003) 2.65
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat Cell Biol (2005) 2.56
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature (1995) 2.54
Functional regulation of p73 and p63: development and cancer. Trends Biochem Sci (2003) 2.29
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. Mol Cell (2002) 2.29
JNK targets p53 ubiquitination and degradation in nonstressed cells. Genes Dev (1998) 2.29
The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol (1996) 2.18
Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol Cell (2004) 1.55
Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Mol Cell Biol (2001) 1.54
An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase. J Biol Chem (2003) 1.47
To die or not to die: how does p53 decide? Oncogene (2004) 1.45
Analyzing JNK and p38 mitogen-activated protein kinase activity. Methods Enzymol (2001) 1.38
p73alpha regulation by Chk1 in response to DNA damage. Mol Cell Biol (2003) 1.36
c-Jun regulates the stability and activity of the p53 homologue, p73. J Biol Chem (2004) 1.29
Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses. J Biol Chem (2002) 1.29
Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med (2004) 1.24
Regulation of p73 by c-Abl through the p38 MAP kinase pathway. Oncogene (2002) 1.19
c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine. J Biol Chem (1995) 1.19
p53 protein variants: structural and functional similarities with p63 and p73 isoforms. Oncogene (2004) 1.04
Small CRISPR RNAs guide antiviral defense in prokaryotes. Science (2008) 17.79
Structural basis for CRISPR RNA-guided DNA recognition by Cascade. Nat Struct Mol Biol (2011) 6.02
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions. Proc Natl Acad Sci U S A (2011) 4.58
A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A (2003) 2.47
Transcriptional regulation by the MAP kinase signaling cascades. Gene (2003) 2.24
In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus. EMBO J (2013) 2.16
MAP kinase signalling cascades and transcriptional regulation. Gene (2012) 1.67
UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA. Curr Biol (2009) 1.45
The JIP1 scaffold protein regulates axonal development in cortical neurons. Curr Biol (2008) 1.40
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth. J Cell Sci (2009) 1.28
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A. Science (2011) 1.27
Docking interactions in the c-Jun N-terminal kinase pathway. J Biol Chem (2003) 1.21
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK. J Biol Chem (2003) 1.10
Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1. Nucleic Acids Res (2010) 1.08
Three-dimensional structure of the Rhodobacter sphaeroides RC-LH1-PufX complex: dimerization and quinone channels promoted by PufX. Biochemistry (2013) 1.03
Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803. J Biol Chem (2012) 0.96
Holliday junction binding and processing by the RuvA protein of Mycoplasma pneumoniae. Eur J Biochem (2002) 0.95
A cyanobacterial chlorophyll synthase-HliD complex associates with the Ycf39 protein and the YidC/Alb3 insertase. Plant Cell (2014) 0.94
Identification of an 8-vinyl reductase involved in bacteriochlorophyll biosynthesis in Rhodobacter sphaeroides and evidence for the existence of a third distinct class of the enzyme. Biochem J (2013) 0.94
Docking interactions of the JNK scaffold protein WDR62. Biochem J (2011) 0.92
Rapid resonance Raman microspectroscopy to probe carbon dioxide fixation by single cells in microbial communities. ISME J (2011) 0.91
A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity. Nat Cell Biol (2015) 0.90
The beta-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its nonconserved N terminus. J Biol Chem (2008) 0.90
Analysis of arginine and lysine methylation utilizing peptide separations at neutral pH and electron transfer dissociation mass spectrometry. J Am Soc Mass Spectrom (2009) 0.88
Shotgun proteome analysis utilising mixed mode (reversed phase-anion exchange chromatography) in conjunction with reversed phase liquid chromatography mass spectrometry analysis. Proteomics (2010) 0.88
Studying the mechanism of RNA separations using RNA chromatography and its application in the analysis of ribosomal RNA and RNA:RNA interactions. J Chromatogr A (2008) 0.87
Use of fluorescent DNA-intercalating dyes in the analysis of DNA via ion-pair reversed-phase denaturing high-performance liquid chromatography. Anal Biochem (2002) 0.85
Characterization and quantification of RNA post-transcriptional modifications using stable isotope labeling of RNA in conjunction with mass spectrometry analysis. Anal Chem (2011) 0.85
Characterization of post-translational modifications of the linker histones H1 and H5 from chicken erythrocytes using mass spectrometry. J Proteome Res (2008) 0.83
Regulation of axon growth by the JIP1-AKT axis. J Cell Sci (2013) 0.81
Quantitative proteomic analysis of intracytoplasmic membrane development in Rhodobacter sphaeroides. Mol Microbiol (2012) 0.80
Multidimensional liquid phase protein separations in conjunction with stable isotope labelling for quantitative proteomics. Proteomics (2007) 0.77
Casein kinase 2 sends extracellular signal-regulated kinase nuclear. Mol Cell Biol (2011) 0.76
Analysis of crRNA Using Liquid Chromatography Electrospray Ionization Mass Spectrometry (LC ESI MS). Methods Mol Biol (2015) 0.75
Identification and characterization of sulfolobus solfataricus P2 proteome using multidimensional liquid phase protein separations. J Proteome Res (2008) 0.75