Prediction of microRNA targets.

MicroRNAs in cancer. Annu Rev Pathol (2009) 4.47

Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet (2008) 4.45

Practical Aspects of microRNA Target Prediction. Curr Mol Med (2011) 2.64

Experimental validation of miRNA targets. Methods (2008) 2.57

MicroRNAs and cardiac pathology. Nat Rev Cardiol (2009) 2.50

MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol (2008) 2.39

MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc. Proc Natl Acad Sci U S A (2008) 2.24

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components. Mol Immunol (2007) 2.24

MicroRNA target prediction by expression analysis of host genes. Genome Res (2008) 2.21

Current tools for the identification of miRNA genes and their targets. Nucleic Acids Res (2009) 2.12

Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. BMC Genomics (2009) 2.02

Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation (2009) 1.92

MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One (2009) 1.81

MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders. Curr Genomics (2009) 1.60

Got target? Computational methods for microRNA target prediction and their extension. Exp Mol Med (2010) 1.49

MicroRNA in ischemic stroke etiology and pathology. Physiol Genomics (2010) 1.48

Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample. Neuropsychopharmacology (2008) 1.42

Computational approaches for microRNA studies: a review. Mamm Genome (2009) 1.39

c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37

Parallel DNA pyrosequencing unveils new zebrafish microRNAs. BMC Genomics (2009) 1.36

Identifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis. BMC Syst Biol (2012) 1.35

Identifying miRNAs, targets and functions. Brief Bioinform (2012) 1.35

Survey of Computational Algorithms for MicroRNA Target Prediction. Curr Genomics (2009) 1.31

Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma. BMC Syst Biol (2010) 1.26

Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques. Mol Syst Biol (2011) 1.25

Individual mRNA expression profiles reveal the effects of specific microRNAs. Genome Biol (2008) 1.18

Endogenous microRNA sponges: evidence and controversy. Nat Rev Genet (2016) 1.15

miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML). PLoS One (2012) 1.13

Prediction of microRNAs affecting mRNA expression during retinal development. BMC Dev Biol (2010) 1.08

Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data. Genome Biol (2009) 1.08

MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells. J Biol Chem (2013) 1.05

A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages. PLoS Pathog (2012) 1.05

microRNAs in viral oncogenesis. Retrovirology (2007) 1.03

Bioinformatic tools for microRNA dissection. Nucleic Acids Res (2015) 1.02

Modeling microRNA-mRNA interactions using PLS regression in human colon cancer. BMC Med Genomics (2011) 0.99

MicroRNAs in metabolism. Acta Physiol (Oxf) (2016) 0.97

Computational methods for the identification of microRNA targets. Open Access Bioinformatics (2010) 0.96

Effects of simulated microgravity on expression profile of microRNA in human lymphoblastoid cells. J Biol Chem (2011) 0.93

miR-Sens--a retroviral dual-luciferase reporter to detect microRNA activity in primary cells. RNA (2012) 0.93

miR-300 inhibits epithelial to mesenchymal transition and metastasis by targeting Twist in human epithelial cancer. Mol Cancer (2014) 0.92

Plant microRNAs and their role in defense against viruses: a bioinformatics approach. BMC Plant Biol (2010) 0.92

Exploration of miRNA families for hypotheses generation. Sci Rep (2013) 0.92

Role for microRNAs in regulating glucocorticoid response and resistance in multiple myeloma. Horm Cancer (2011) 0.90

Computational Methods for MicroRNA Target Prediction. Genes (Basel) (2014) 0.90

New information content in RNA base pairing deduced from quantitative analysis of high-resolution structures. Methods (2009) 0.89

Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools. BMC Bioinformatics (2012) 0.88

In-Silico Algorithms for the Screening of Possible microRNA Binding Sites and Their Interactions. Curr Genomics (2013) 0.88

Correlated mRNAs and miRNAs from co-expression and regulatory networks affect porcine muscle and finally meat properties. BMC Genomics (2013) 0.87

RFMirTarget: predicting human microRNA target genes with a random forest classifier. PLoS One (2013) 0.87

MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer? Int J Mol Sci (2012) 0.87

High-throughput experimental studies to identify miRNA targets directly, with special focus on the mammalian brain. Brain Res (2010) 0.86

Why have tobacco control policies stalled? Using genetic moderation to examine policy impacts. PLoS One (2012) 0.86

MicroRNA-138 suppresses neutrophil gelatinase-associated lipocalin expression and inhibits tumorigenicity. PLoS One (2012) 0.85

Identification of novel microRNAs in Xenopus laevis metaphase II arrested eggs. Genesis (2012) 0.85

Gene bi-targeting by viral and human miRNAs. BMC Bioinformatics (2010) 0.85

Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Res (2015) 0.84

Bioinformatic Resources of microRNA Sequences, Gene Targets, and Genetic Variation. Front Genet (2012) 0.84

A scoring matrix approach to detecting miRNA target sites. Algorithms Mol Biol (2008) 0.84

Infection with street strain rabies virus induces modulation of the microRNA profile of the mouse brain. Virol J (2012) 0.84

MicroRNAs, Major Players in B Cells Homeostasis and Function. Front Immunol (2014) 0.83

Identifying microRNA targets in different gene regions. BMC Bioinformatics (2014) 0.83

MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro. Age (Dordr) (2013) 0.83

Expression and regulation of mouse selenoprotein P transcript variants differing in non-coding RNA. RNA Biol (2012) 0.83

MicroRNA-194 Modulates Glucose Metabolism and Its Skeletal Muscle Expression Is Reduced in Diabetes. PLoS One (2016) 0.81

Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy. Mol Biosyst (2014) 0.80

Tiny giants of gene regulation: experimental strategies for microRNA functional studies. Wiley Interdiscip Rev Dev Biol (2016) 0.80

Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review). Int J Oncol (2016) 0.79

ReNE: a cytoscape plugin for regulatory network enhancement. PLoS One (2014) 0.79

hLGDB: a database of human lysosomal genes and their regulation. Database (Oxford) (2013) 0.79

Target Gene and Function Prediction of Differentially Expressed MicroRNAs in Lactating Mammary Glands of Dairy Goats. Int J Genomics (2013) 0.78

Dampening the signals transduced through hedgehog via microRNA miR-7 facilitates notch-induced tumourigenesis. PLoS Biol (2013) 0.78

Global transcriptional and miRNA insights into bases of heterosis in hybridization of Cyprinidae. Sci Rep (2015) 0.77

Modeling post-transcriptional regulation activity of small non-coding RNAs in Escherichia coli. BMC Bioinformatics (2009) 0.77

Finding quasi-modules of human and viral miRNAs: a case study of human cytomegalovirus (HCMV). BMC Bioinformatics (2012) 0.77

New Approaches to Comparative and Animal Stress Biology Research in the Post-genomic Era: A Contextual Overview. Comput Struct Biotechnol J (2014) 0.77

Cross-kingdom sequence similarities between human micro-RNAs and plant viruses. Commun Integr Biol (2013) 0.76

Low miR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma. Mol Med (2016) 0.76

A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells. BMC Genomics (2014) 0.76

Computational developments in microRNA-regulated protein-protein interactions. BMC Syst Biol (2014) 0.76

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation. Appl Microbiol Biotechnol (2014) 0.76

MicroRNA Modulation during the In vitro Culture of Hematopoietic Stem Cells Prior to Transplantation. Iran J Med Sci (2017) 0.75

Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools. Genes (Basel) (2016) 0.75

Modeling miRNA-mRNA interactions: fitting chemical kinetics equations to microarray data. BMC Syst Biol (2014) 0.75

miR-181 interacts with signaling adaptor molecule DENN/MADD and enhances TNF-induced cell death. PLoS One (2017) 0.75

Targeting microRNAs: a new action mechanism of natural compounds. Oncotarget (2016) 0.75

Overexpression of Exosomal Cardioprotective miRNAs Mitigates Hypoxia-Induced H9c2 Cells Apoptosis. Int J Mol Sci (2017) 0.75

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients. Liver Int (2015) 0.75

Analysis of microRNA expression during the torpor-arousal cycle of a mammalian hibernator, the 13-lined ground squirrel. Physiol Genomics (2016) 0.75

Gene-microRNA network module analysis for ovarian cancer. BMC Syst Biol (2016) 0.75

Grouping miRNAs of similar functions via weighted information content of gene ontology. BMC Bioinformatics (2016) 0.75

miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res (2006) 39.25

miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61

Human MicroRNA targets. PLoS Biol (2004) 34.51

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (2006) 18.14

Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24

Identification of virus-encoded microRNAs. Science (2004) 12.56

MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16

microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity (2007) 6.72

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev (2007) 4.69

RNA editing of human microRNAs. Genome Biol (2006) 4.16

Detecting microRNA binding and siRNA off-target effects from expression data. Nat Methods (2008) 3.41

Detection of functional modules from protein interaction networks. Proteins (2004) 3.08

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet (2009) 3.05

Construction, visualisation, and clustering of transcription networks from microarray expression data. PLoS Comput Biol (2007) 2.73

Network visualization and analysis of gene expression data using BioLayout Express(3D). Nat Protoc (2009) 2.66

Evaluation of annotation strategies using an entire genome sequence. Bioinformatics (2003) 2.66

The miR-144/451 locus is required for erythroid homeostasis. J Exp Med (2010) 2.54

Computational prediction of protein-protein interactions. Mol Biotechnol (2007) 2.35

BioLayout(Java): versatile network visualisation of structural and functional relationships. Appl Bioinformatics (2005) 2.26

Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation (2012) 2.14

Kraken: a set of tools for quality control and analysis of high-throughput sequence data. Methods (2013) 1.92

Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization. Genes Dev (2009) 1.84

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature (2011) 1.77

COmplete GENome Tracking (COGENT): a flexible data environment for computational genomics. Bioinformatics (2003) 1.77

Myriads of protein families, and still counting. Genome Biol (2003) 1.75

RNAcentral: A vision for an international database of RNA sequences. RNA (2011) 1.73

Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res (2010) 1.59

Annotation of mammalian primary microRNAs. BMC Genomics (2008) 1.53

Classification schemes for protein structure and function. Nat Rev Genet (2003) 1.52

A logic-based diagram of signalling pathways central to macrophage activation. BMC Syst Biol (2008) 1.49

MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells. J Biol Chem (2012) 1.43

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids. Nucleic Acids Res (2010) 1.41

MagicMatch--cross-referencing sequence identifiers across databases. Bioinformatics (2005) 1.34

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell (2013) 1.29

Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet (2012) 1.28

Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proc Natl Acad Sci U S A (2010) 1.20

Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis. BMC Genomics (2010) 1.20

MapMi: automated mapping of microRNA loci. BMC Bioinformatics (2010) 1.15

SylArray: a web server for automated detection of miRNA effects from expression data. Bioinformatics (2010) 1.07

MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs. PLoS One (2012) 0.99

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia. Mol Cancer (2014) 0.98

Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation. BMC Genomics (2009) 0.96

MiR-221 influences effector functions and actin cytoskeleton in mast cells. PLoS One (2011) 0.95

The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression. Mol Cancer (2010) 0.94

LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Res (2013) 0.92

Denoising inferred functional association networks obtained by gene fusion analysis. BMC Genomics (2007) 0.90

CoGenT++: an extensive and extensible data environment for computational genomics. Bioinformatics (2005) 0.89

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect Immun (2012) 0.89

miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs. Front Genet (2013) 0.89

Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data. Hum Genet (2011) 0.85

Messenger RNA and microRNA profiling during early mouse EB formation. Gene Expr Patterns (2011) 0.84

Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state. J Pathol (2013) 0.83

Evolutionary and functional insights into Leishmania META1: evidence for lateral gene transfer and a role for META1 in secretion. BMC Evol Biol (2011) 0.81

Large-scale analysis of microRNA evolution. BMC Genomics (2012) 0.81

Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines. PLoS One (2012) 0.80

Detecting and comparing non-coding RNAs in the high-throughput era. Int J Mol Sci (2013) 0.78

A Neuronal Transcriptome Response Involving Stress Pathways is Buffered by Neuronal microRNAs. Front Neurosci (2012) 0.77

Mapping functional associations in the entire genome of Drosophila melanogaster using fusion analysis. Comp Funct Genomics (2003) 0.75