Published in BMC Genomics on June 12, 2007
Serum microRNAs are promising novel biomarkers. PLoS One (2008) 8.69
Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A (2009) 6.91
The microRNA spectrum in 12 body fluids. Clin Chem (2010) 6.82
miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA (2008) 5.48
Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40
An analysis of human microRNA and disease associations. PLoS One (2008) 5.21
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Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA (2007) 3.91
Distinctive patterns of microRNA expression in primary muscular disorders. Proc Natl Acad Sci U S A (2007) 3.72
Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer (2010) 2.95
Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb Perspect Biol (2009) 2.89
Circulating microRNAs in breast cancer and healthy subjects. BMC Res Notes (2009) 2.78
MicroRNA-206: the skeletal muscle-specific myomiR. Biochim Biophys Acta (2008) 2.64
Structure and activity of putative intronic miRNA promoters. RNA (2010) 2.50
Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer. BMC Mol Biol (2008) 2.30
Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital. Hepatology (2013) 2.24
Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. Circ Cardiovasc Genet (2010) 2.24
MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity. Neuro Oncol (2012) 2.02
Intra-platform repeatability and inter-platform comparability of microRNA microarray technology. PLoS One (2009) 2.02
A blood based 12-miRNA signature of Alzheimer disease patients. Genome Biol (2013) 1.99
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1. PLoS Pathog (2009) 1.94
A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets. Nat Protoc (2009) 1.85
MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells. J Transl Med (2009) 1.85
Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. BMC Genomics (2010) 1.84
MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One (2009) 1.81
MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation. Int J Legal Med (2010) 1.78
Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma. PLoS One (2012) 1.76
Measuring microRNAs: comparisons of microarray and quantitative PCR measurements, and of different total RNA prep methods. BMC Biotechnol (2008) 1.75
miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. Mol Cell Biol (2009) 1.70
Correlation of expression profiles between microRNAs and mRNA targets using NCI-60 data. BMC Genomics (2009) 1.66
MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene (2012) 1.63
Characterization of microRNAs involved in embryonic stem cell states. Stem Cells Dev (2010) 1.62
Plasma microRNA biomarkers for detection of mild cognitive impairment. Aging (Albany NY) (2012) 1.61
Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia (2010) 1.60
Human microRNA oncogenes and tumor suppressors show significantly different biological patterns: from functions to targets. PLoS One (2010) 1.59
Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy. PLoS One (2013) 1.58
In search of adrenocortical stem and progenitor cells. Endocr Rev (2009) 1.51
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest (2013) 1.49
Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids. Am J Physiol Endocrinol Metab (2008) 1.45
Emerging role of microRNAs in liver diseases. World J Gastroenterol (2009) 1.45
Tissues from routine pathology archives are suitable for microRNA analyses by quantitative PCR. J Clin Pathol (2008) 1.44
miR-375 inhibits differentiation of neurites by lowering HuD levels. Mol Cell Biol (2010) 1.43
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med (2010) 1.41
Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord (2009) 1.40
Transcriptional Perturbations in Graft Rejection. Transplantation (2015) 1.40
A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC Syst Biol (2010) 1.40
Mechanical Stretch Inhibits MicroRNA499 via p53 to Regulate Calcineurin-A Expression in Rat Cardiomyocytes. PLoS One (2016) 1.38
SZGR: a comprehensive schizophrenia gene resource. Mol Psychiatry (2010) 1.36
MicroRNAs as a selective channel of communication between competing RNAs: a steady-state theory. Biophys J (2013) 1.35
MicroRNAs can regulate human APP levels. Mol Neurodegener (2008) 1.34
Macro view of microRNA function in osteoarthritis. Nat Rev Rheumatol (2012) 1.33
Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer. J Transl Med (2012) 1.31
Atrial fibrillation and microRNAs. Front Physiol (2014) 1.31
miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines. Biochem Biophys Res Commun (2010) 1.30
Elevated miR-499 levels blunt the cardiac stress response. PLoS One (2011) 1.28
Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet (2012) 1.28
Clustered microRNAs' coordination in regulating protein-protein interaction network. BMC Syst Biol (2009) 1.28
MicroRNA networks in mouse lung organogenesis. PLoS One (2010) 1.28
Sharing and Specificity of Co-expression Networks across 35 Human Tissues. PLoS Comput Biol (2015) 1.27
Consensus miRNA expression profiles derived from interplatform normalization of microarray data. RNA (2009) 1.27
Cepred: predicting the co-expression patterns of the human intronic microRNAs with their host genes. PLoS One (2009) 1.27
MicroRNA regulation of homeostatic synaptic plasticity. Proc Natl Acad Sci U S A (2011) 1.26
A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia. PLoS Pathog (2011) 1.26
MicroRNAs and the regulation of vector tropism. Mol Ther (2008) 1.25
Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. PLoS One (2012) 1.24
A high throughput experimental approach to identify miRNA targets in human cells. Nucleic Acids Res (2009) 1.24
Estrogen receptor α signaling regulates breast tumor-initiating cells by down-regulating miR-140 which targets the transcription factor SOX2. J Biol Chem (2012) 1.23
General principals of miRNA biogenesis and regulation in the brain. Neuropsychopharmacology (2012) 1.23
BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome. Breast Cancer Res (2013) 1.22
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. J Transl Med (2011) 1.22
Circulating miRNA biomarkers for Alzheimer's disease. PLoS One (2013) 1.22
miRNAminer: a tool for homologous microRNA gene search. BMC Bioinformatics (2008) 1.21
Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism. Autism Res (2008) 1.21
Detection of metastatic head and neck squamous cell carcinoma using the relative expression of tissue-specific mir-205. Transl Oncol (2008) 1.21
Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle. J Nutr (2009) 1.20
Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease. PLoS One (2011) 1.19
Ultra-deep sequencing reveals the microRNA expression pattern of the human stomach. PLoS One (2010) 1.19
Integrating the MicroRNome into the study of lung disease. Am J Respir Crit Care Med (2008) 1.19
Individual mRNA expression profiles reveal the effects of specific microRNAs. Genome Biol (2008) 1.18
Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes. BMC Musculoskelet Disord (2012) 1.17
Silicon nanowires with high-k hafnium oxide dielectrics for sensitive detection of small nucleic acid oligomers. ACS Nano (2012) 1.17
MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas. Br J Cancer (2010) 1.16
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Transcriptional regulation of mammalian miRNA genes. Genomics (2010) 1.16
MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. Nucleic Acids Res (2012) 1.15
Targeting microRNAs in obesity. Expert Opin Ther Targets (2009) 1.14
Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma. BMC Cancer (2012) 1.14
In situ detection of mature microRNAs by labeled extension on ultramer templates. Biotechniques (2009) 1.14
p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. Cancer Res (2011) 1.14
Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients. J Transl Med (2010) 1.13
MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met. PLoS One (2013) 1.12
Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression. J Biol Chem (2012) 1.11
Identification of miR-23a as a novel microRNA normalizer for relative quantification in human uterine cervical tissues. Exp Mol Med (2011) 1.09
Extracellular vesicles and reproduction-promotion of successful pregnancy. Cell Mol Immunol (2014) 1.08
Altered expression of microRNAs in the myocardium of rats with acute myocardial infarction. BMC Cardiovasc Disord (2010) 1.07
Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PLoS One (2013) 1.06
Genome-wide and species-wide in silico screening for intragenic MicroRNAs in human, mouse and chicken. PLoS One (2013) 1.06
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A (2004) 44.81
A microRNA polycistron as a potential human oncogene. Nature (2005) 40.21
Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55
Human MicroRNA targets. PLoS Biol (2004) 34.51
Silencing of microRNAs in vivo with 'antagomirs'. Nature (2005) 32.56
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2002) 32.26
Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res (2005) 29.17
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A (2004) 28.29
miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A (2005) 21.51
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84
Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol (2003) 16.63
Dicer is essential for mouse development. Nat Genet (2003) 15.87
MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell (2005) 15.26
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15
A pancreatic islet-specific microRNA regulates insulin secretion. Nature (2004) 15.02
Identification of mammalian microRNA host genes and transcription units. Genome Res (2004) 14.63
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA (2005) 14.14
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci U S A (2004) 13.66
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev (2005) 12.15
miRNAs, cancer, and stem cell division. Cell (2005) 12.15
A brain-specific microRNA regulates dendritic spine development. Nature (2006) 10.18
MicroRNA functions in animal development and human disease. Development (2005) 8.41
microPrimer: the biogenesis and function of microRNA. Development (2005) 8.19
Cell-type-specific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci U S A (2006) 7.11
MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues. Genome Res (2004) 6.98
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res (2007) 6.57
Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proc Natl Acad Sci U S A (2005) 6.54
Processing of intronic microRNAs. EMBO J (2007) 6.32
Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A (2006) 6.19
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78
MicroRNAs as oncogenes and tumor suppressors. N Engl J Med (2005) 5.67
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol (2006) 5.40
A public gene trap resource for mouse functional genomics. Nat Genet (2004) 3.96
Comparative genomics: genome-wide analysis in metazoan eukaryotes. Nat Rev Genet (2003) 3.45
Familial cancer associated with a polymorphism in ARLTS1. N Engl J Med (2005) 3.35
A DNA microarray survey of gene expression in normal human tissues. Genome Biol (2005) 2.90
GenomeTrafac: a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs. Nucleic Acids Res (2006) 1.17
Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell. Hum Mol Genet (2005) 1.16
A microRNA component of the p53 tumour suppressor network. Nature (2007) 19.25
Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes. N Engl J Med (2008) 10.88
A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures. Nat Genet (2008) 8.44
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res (2007) 6.57
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer (2006) 5.47
Real-time PCR quantification of precursor and mature microRNA. Methods (2008) 4.12
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis (2008) 3.84
miR-34 miRNAs provide a barrier for somatic cell reprogramming. Nat Cell Biol (2011) 2.79
High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Res (2008) 2.71
The SNPlex genotyping system: a flexible and scalable platform for SNP genotyping. J Biomol Tech (2005) 2.64
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A (2007) 2.60
Defining embryonic stem cell identity using differentiation-related microRNAs and their potential targets. Mamm Genome (2007) 1.88
Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila. Genes Dev (2010) 1.84
Multiplexing RT-PCR for the detection of multiple miRNA species in small samples. Biochem Biophys Res Commun (2006) 1.69
A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell (2013) 1.49
The microRNA body map: dissecting microRNA function through integrative genomics. Nucleic Acids Res (2011) 1.41
Nonrestrictive developmental regulation of microRNA gene expression. Mamm Genome (2006) 1.41
MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia. Haematologica (2011) 1.21
MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes. J Immunol (2011) 1.18
MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res (2011) 1.17
Multiplex gene expression analysis for high-throughput drug discovery: screening and analysis of compounds affecting genes overexpressed in cancer cells. Mol Cancer Ther (2002) 1.14
Choline kinase alpha and hexokinase-2 protein expression in hepatocellular carcinoma: association with survival. PLoS One (2012) 1.12
Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J (2010) 1.08
MicroRNA and stem cell regulation. Curr Opin Mol Ther (2009) 1.08
The impact of the iPLEDGE program on isotretinoin fetal exposure in an integrated health care system. J Am Acad Dermatol (2011) 1.08
Stem-loop RT-PCR quantification of siRNAs in vitro and in vivo. Oligonucleotides (2009) 1.05
MicroRNAs in embryonic stem cells. J Cell Physiol (2009) 1.04
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples. Clin Cancer Res (2011) 1.03
Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo. Toxicol Sci (2005) 1.01
Quantitation of microRNAs by real-time RT-qPCR. Methods Mol Biol (2011) 0.92
Stem-loop RT-qPCR for microRNA expression profiling. Methods Mol Biol (2012) 0.92
Symptomatic subclavian vein stenosis and occlusion in hemodialysis patients with transvenous pacemakers. Ann Vasc Surg (2003) 0.86
Profiling of serum bile acids in a healthy Chinese population using UPLC-MS/MS. J Proteome Res (2015) 0.85
A cross-cultural comparison of British and Chinese beliefs about the causes, behaviour manifestations and treatment of schizophrenia. Psychiatry Res (2007) 0.85
A risk management program aimed at preventing fetal exposure to isotretinoin: retrospective cohort study. J Am Acad Dermatol (2006) 0.80
A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis. Genes Dev (2014) 0.80
Determination of optimal replicate number for validation of imprecision using fluorescence cell-based assays: proposed practical method. Cytometry B Clin Cytom (2013) 0.77
Gene expression in stem cells. Crit Rev Eukaryot Gene Expr (2009) 0.77
In vitro translation and computational analyses of human profilin multimers. Proc West Pharmacol Soc (2005) 0.76
The youngest member of the old school. Hawaii J Med Public Health (2013) 0.75
Laparoscopic donor nephrectomy in Hawaii. Hawaii Med J (2002) 0.75