Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 2039719)

Published in J Mol Biol on June 09, 2007

Authors

Manabu Yasui1, Naomi Suzuki, Xiaoping Liu, Yoshinori Okamoto, Sung Yeon Kim, Y R Santosh Laxmi, Shinya Shibutani

Author Affiliations

1: Laboratory of Chemical Biology, Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794-8651, USA.

Articles cited by this

The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N Engl J Med (1995) 11.08

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature (1991) 9.70

Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell (2004) 6.12

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Nature (2000) 5.48

Postmenopausal hormone therapy and mortality. N Engl J Med (1997) 4.96

Menopausal hormone replacement therapy and risk of ovarian cancer. JAMA (2002) 4.39

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J Biol Chem (1990) 3.38

Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J (1999) 3.31

Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell (2005) 3.25

Novel blunt-end addition reactions catalyzed by DNA polymerase I of Escherichia coli. J Mol Biol (1987) 3.16

Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells. Proc Natl Acad Sci U S A (1993) 2.55

Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Nature (2004) 2.40

Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Genes Dev (2000) 2.38

Nearest neighbor influences on DNA polymerase insertion fidelity. J Biol Chem (1989) 2.29

Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. Proc Natl Acad Sci U S A (1999) 2.15

Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. J Biol Chem (2000) 2.06

The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4. J Biol Chem (2003) 1.98

Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB. Genes Cells (1999) 1.79

DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers. Int J Cancer (2004) 1.72

Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2004) 1.64

Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr Opin Genet Dev (2004) 1.61

Role of human DNA polymerase kappa as an extender in translesion synthesis. Proc Natl Acad Sci U S A (2002) 1.51

The expanding polymerase universe. Nat Rev Mol Cell Biol (2000) 1.49

Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. DNA Repair (Amst) (2003) 1.38

Replication of damaged DNA by translesion synthesis in human cells. FEBS Lett (2005) 1.32

Enzymatic switching for efficient and accurate translesion DNA replication. Nucleic Acids Res (2004) 1.30

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29

The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone. Chem Res Toxicol (1999) 1.26

Detection of estrogen DNA-adducts in human breast tumor tissue and healthy tissue by combined nano LC-nano ES tandem mass spectrometry. J Am Soc Mass Spectrom (2003) 1.21

Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical. Chem Res Toxicol (1998) 1.20

Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones. Carcinogenesis (1995) 1.18

On the mechanism of frameshift (deletion) mutagenesis in vitro. J Biol Chem (1993) 1.18

Role of quinoids in estrogen carcinogenesis. Chem Res Toxicol (1998) 1.15

Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells. Carcinogenesis (1999) 1.10

Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases. Chem Res Toxicol (2001) 1.09

Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2006) 1.08

A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines. Chem Res Toxicol (2000) 1.06

Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. DNA Repair (Amst) (2003) 1.03

Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin. Chem Res Toxicol (2005) 0.99

Translesion synthesis past equine estrogen-derived 2'-deoxycytidine DNA adducts by human DNA polymerases eta and kappa. Biochemistry (2004) 0.95

Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha. Chem Res Toxicol (2002) 0.95

Mutagenic events induced by 4-hydroxyequilin in supF shuttle vector plasmid propagated in human cells. Carcinogenesis (2003) 0.93

Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. Biochemistry (2005) 0.92

Quantitation of base substitutions and deletions induced by chemical mutagens during DNA synthesis in vitro. Chem Res Toxicol (1994) 0.90

Conformations of stereoisomeric base adducts to 4-hydroxyequilenin. Chem Res Toxicol (2003) 0.88

Mechanism of frameshift (deletion) generated by acetylaminofluorene-derived DNA adducts in vitro. Biochemistry (2004) 0.88

The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro. Chem Res Toxicol (1998) 0.88

Miscoding properties of 3,N4-etheno-2'-deoxycytidine in reactions catalyzed by mammalian DNA polymerases. Biochemistry (1996) 0.85

Translesional synthesis on DNA templates containing an estrogen quinone-derived adduct: N2-(2-hydroxyestron-6-yl)-2'-deoxyguanosine and N6-(2-hydroxyestron-6-yl)-2'-deoxyadenosine. Biochemistry (1998) 0.81

Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone. Chem Res Toxicol (2001) 0.80

Articles by these authors

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nat Med (2009) 3.27

The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma. Cell (2011) 2.83

Aristolochic acid and the etiology of endemic (Balkan) nephropathy. Proc Natl Acad Sci U S A (2007) 2.52

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL). Nat Genet (2011) 1.99

Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall. Am J Physiol Heart Circ Physiol (2008) 1.88

Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes. Am J Physiol Cell Physiol (2005) 1.59

Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress. Proc Natl Acad Sci U S A (2005) 1.51

Transcarotid artery endovascular reconstruction of the aortic arch by modified bifurcated stent graft for Stanford type A dissection. Asian J Surg (2007) 1.49

Formation of tamoxifen-DNA adducts in human endometrial explants exposed to alpha-hydroxytamoxifen. Chem Res Toxicol (2005) 1.49

Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation. J Biol Chem (2004) 1.48

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry (2002) 1.47

Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues. Biochemistry (2003) 1.41

Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in mice. Am J Physiol Heart Circ Physiol (2010) 1.29

A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase. PLoS Negl Trop Dis (2010) 1.29

Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages. Am J Physiol Heart Circ Physiol (2008) 1.25

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling. EMBO J (2011) 1.24

MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma. Mol Cell Biochem (2014) 1.20

Geometric and electronic structure and reactivity of a mononuclear "side-on" nickel(III)-peroxo complex. Nat Chem (2009) 1.19

Primary myoepithelial carcinoma of palate. World J Surg Oncol (2011) 1.18

Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth. Brain Res (2011) 1.16

Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets. Mol Cancer Ther (2006) 1.15

Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis. Drug Metab Dispos (2006) 1.12

Selective toxicity of aristolochic acids I and II. Drug Metab Dispos (2007) 1.11

A novel PRPF31 splice-site mutation in a Chinese family with autosomal dominant retinitis pigmentosa. Mol Vis (2004) 1.11

Increased DNA damage in ALDH2-deficient alcoholics. Chem Res Toxicol (2006) 1.10

Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2013) 1.09

NO-donating aspirin inhibits the activation of NF-kappaB in human cancer cell lines and Min mice. Carcinogenesis (2008) 1.08

Retracted Hybrid endovascular repair in aortic arch pathologies: a retrospective study. Int J Mol Sci (2010) 1.07

Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site. Biochemistry (2002) 1.07

The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone. Structure (2010) 1.06

MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma. Mol Cancer (2011) 1.05

Structural characterization and remarkable axial ligand effect on the nucleophilic reactivity of a nonheme manganese(III)-peroxo complex. Angew Chem Int Ed Engl (2009) 1.04

Direct and indirect roles of cytochrome b in the mediation of superoxide generation and NO catabolism by mitochondrial succinate-cytochrome c reductase. J Biol Chem (2006) 1.04

Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. Free Radic Biol Med (2004) 1.03

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells. Development (2013) 1.02

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2012) 1.01

Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation. J Biol Chem (2005) 1.00

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. Bioorg Med Chem Lett (2012) 1.00

DFT study of a series of crown-4 ethers and their selectivity trend for alkali metal cations: Li+ and Na+. J Mol Model (2008) 1.00

Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases. J Mol Biol (2008) 1.00

A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res (2007) 1.00

Extensive chromosomal breaks are induced by tamoxifen and estrogen in DNA repair-deficient cells. Cancer Res (2004) 0.99

Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts. Free Radic Biol Med (2002) 0.98

Characterization of the mechanism of cytochrome P450 reductase-cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates. J Biol Chem (2006) 0.96

Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall. Nitric Oxide (2010) 0.96

miR-200b as a prognostic factor in breast cancer targets multiple members of RAB family. J Transl Med (2014) 0.95

Translesion synthesis past equine estrogen-derived 2'-deoxycytidine DNA adducts by human DNA polymerases eta and kappa. Biochemistry (2004) 0.95

LRRC4 inhibits glioma cell growth and invasion through a miR-185-dependent pathway. Curr Cancer Drug Targets (2012) 0.94

Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum. Bioorg Med Chem Lett (2012) 0.94

Mutagenic events induced by 4-hydroxyequilin in supF shuttle vector plasmid propagated in human cells. Carcinogenesis (2003) 0.93

Stress triggered changes in gene expression in adrenal medulla: transcriptional responses to acute and chronic stress. Cell Mol Neurobiol (2006) 0.92

Multiple Scedosporium apiospermum abscesses in a woman survivor of a tsunami in northeastern Japan: a case report. J Med Case Rep (2011) 0.92

Genotoxic mechanism of tamoxifen in developing endometrial cancer. Drug Metab Rev (2004) 0.92

Miscoding events during DNA synthesis past the nitration-damaged base 8-nitroguanine. Biochemistry (2005) 0.92

Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents. Int J Cancer (2010) 0.91

Synthesis and antimuscarinic properties of quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives as novel muscarinic receptor antagonists. J Med Chem (2005) 0.91

Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma. J Cancer Res Ther (2015) 0.90

GSK3beta affects apical-basal polarity and cell-cell adhesion by regulating aPKC levels. Dev Dyn (2010) 0.90

Colorimetric and resistive polymer electrolyte thin films for real-time humidity sensors. ACS Appl Mater Interfaces (2012) 0.90

Molecular regulation of gene expression of catecholamine biosynthetic enzymes by stress: sympathetic ganglia versus adrenal medulla. Ann N Y Acad Sci (2004) 0.90

Translesion synthesis past equine estrogen-derived 2'-deoxyadenosine DNA adducts by human DNA polymerases eta and kappa. Biochemistry (2006) 0.90

Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol. Carcinogenesis (2007) 0.89

32P-Postlabeling/polyacrylamide gel electrophoresis analysis: application to the detection of DNA adducts. Chem Res Toxicol (2002) 0.89

Oxidative DNA damage in XPC-knockout and its wild mice treated with equine estrogen. Chem Res Toxicol (2008) 0.89

Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells. Biochemistry (2004) 0.89

NO-donating aspirin induces phase II enzymes in vitro and in vivo. Carcinogenesis (2005) 0.89

Neural-Based Adaptive Output-Feedback Control for a Class of Nonstrict-Feedback Stochastic Nonlinear Systems. IEEE Trans Cybern (2014) 0.88

Endovascular chimney technique of aortic arch pathologies: a systematic review. Ann Vasc Surg (2012) 0.88

Reactivity of a cobalt(III)-peroxo complex in oxidative nucleophilic reactions. J Inorg Biochem (2008) 0.88

NO-donating aspirin inhibits both the expression and catalytic activity of inducible nitric oxide synthase in HT-29 human colon cancer cells. Biochem Pharmacol (2005) 0.88

Mechanism of frameshift (deletion) generated by acetylaminofluorene-derived DNA adducts in vitro. Biochemistry (2004) 0.88

miR-200b as a prognostic factor targets multiple members of RAB family in glioma. Med Oncol (2014) 0.87

Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer. Med Oncol (2014) 0.87

Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene. Biochemistry (2004) 0.87

Robust Adaptive Neural Tracking Control for a Class of Stochastic Nonlinear Interconnected Systems. IEEE Trans Neural Netw Learn Syst (2015) 0.87

Differential effects of stress on gene transcription factors in catecholaminergic systems. Ann N Y Acad Sci (2004) 0.87

DIPOS: database of interacting proteins in Oryza sativa. Mol Biosyst (2011) 0.85

Loss of topoisomerase I function affects the RpoS-dependent and GAD systems of acid resistance in Escherichia coli. Microbiology (2005) 0.85

Competence-dependent endogenous DNA rearrangement and uptake of extracellular DNA give a natural variant of Streptococcus mutans without biofilm formation. J Bacteriol (2011) 0.85

miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2011) 0.85