PubRank

Stuart K Calderwood

Author PubWeight™ 75.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002 6.16
2 Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 2005 5.22
3 Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes. J Immunol 2006 2.13
4 Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene 2005 1.64
5 OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Mol Pharmacol 2008 1.52
6 The dual immunoregulatory roles of stress proteins. Trends Biochem Sci 2008 1.51
7 Role of scavenger receptors in the binding and internalization of heat shock protein 70. J Immunol 2006 1.48
8 The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. J Immunol 2007 1.43
9 Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J Biol Chem 2002 1.43
10 Mechanisms for Hsp70 secretion: crossing membranes without a leader. Methods 2007 1.42
11 Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo. Cell Stress Chaperones 2005 1.41
12 Induction of hsp70-mediated Th17 autoimmunity can be exploited as immunotherapy for metastatic prostate cancer. Cancer Res 2007 1.37
13 Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J Immunol 2002 1.34
14 Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells. FEBS Lett 2005 1.34
15 The role of heat shock proteins in antigen cross presentation. Front Immunol 2012 1.33
16 Targeting the oncogene and kinome chaperone CDC37. Nat Rev Cancer 2008 1.32
17 Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants. Cell Stress Chaperones 2010 1.31
18 A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use. J Immunol 2009 1.28
19 mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. PLoS One 2012 1.25
20 Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. J Biol Chem 2005 1.22
21 Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol 2010 1.20
22 Heat-shock proteins in cancer vaccines: agents of antigen cross-presentation. Expert Rev Vaccines 2008 1.19
23 Targeting Cdc37 inhibits multiple signaling pathways and induces growth arrest in prostate cancer cells. Cancer Res 2007 1.19
24 Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1. Mol Cell Biol 2003 1.18
25 Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol 2006 1.16
26 Heat shock proteins and cancer vaccines: developments in the past decade and chaperoning in the decade to come. Expert Rev Vaccines 2011 1.11
27 Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J Biol Chem 2003 1.10
28 The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways. Shock 2006 1.10
29 Co-expression of steroid receptors (estrogen receptor alpha and/or progesterone receptors) and Her-2/neu: Clinical implications. J Steroid Biochem Mol Biol 2006 1.09
30 Antitumor immunity can be uncoupled from autoimmunity following heat shock protein 70-mediated inflammatory killing of normal pancreas. Cancer Res 2009 1.09
31 OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells. PLoS One 2013 1.09
32 The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions? Cell Stress Chaperones 2009 1.08
33 T cell activation by heat shock protein 70 vaccine requires TLR signaling and scavenger receptor expressed by endothelial cells-1. J Immunol 2009 1.05
34 Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2. Biochem Biophys Res Commun 2003 1.03
35 Protein kinase A binds and activates heat shock factor 1. PLoS One 2010 1.02
36 Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers. Breast Cancer Res 2012 1.02
37 Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells. Int J Hyperthermia 2006 1.02
38 Double-stranded RNA-dependent protein kinase (pkr) is essential for thermotolerance, accumulation of HSP70, and stabilization of ARE-containing HSP70 mRNA during stress. J Biol Chem 2002 1.00
39 Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress. J Biol Chem 2004 0.99
40 Induction of cytotoxic T lymphocytes against ovarian cancer-initiating cells. Int J Cancer 2011 0.98
41 Expression of a dominant negative heat shock factor-1 construct inhibits aneuploidy in prostate carcinoma cells. J Biol Chem 2004 0.97
42 Cell fusion: from hybridoma to dendritic cell-based vaccine. Expert Rev Vaccines 2008 0.95
43 NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells. Biochem Biophys Res Commun 2002 0.93
44 Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation. J Immunol 2013 0.93
45 Heat shock factor 1 contains two functional domains that mediate transcriptional repression of the c-fos and c-fms genes. J Biol Chem 2002 0.91
46 Protein kinase A regulates molecular chaperone transcription and protein aggregation. PLoS One 2011 0.90
47 Stress proteins in aging and life span. Int J Hyperthermia 2013 0.90
48 Oxidative stress impairs the heat stress response and delays unfolded protein recovery. PLoS One 2009 0.90
49 Investigating receptors for extracellular heat shock proteins. Methods Mol Biol 2011 0.87
50 Autophagy, protein aggregation and hyperthermia: a mini-review. Int J Hyperthermia 2011 0.87
51 Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people. Cell Stress Chaperones 2011 0.85
52 Plasma adenosine triphosphate and heat shock protein 72 concentrations after aerobic and eccentric exercise. Exerc Immunol Rev 2011 0.84
53 Purification, preparation, and use of chaperone-peptide complexes for tumor immunotherapy. Methods Mol Biol 2013 0.82
54 Hyperthermia classic article commentary: 'Re-induction of hsp70 synthesis: an assay for thermotolerance' by Gloria C. Li and Johnson Y. Mak, International Journal of Hyperthermia 1989;5:389-403. Int J Hyperthermia 2009 0.81
55 The role of heat shock factors in stress-induced transcription. Methods Mol Biol 2011 0.79
56 Preparation of a heat-shock protein 70-based vaccine from DC-tumor fusion cells. Methods Mol Biol 2011 0.78
57 Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment. Breast Cancer Res 2010 0.78
58 Heat shock proteins in physiology and pathology: the Berlin meeting. Cell Stress Chaperones 2007 0.77
59 From stress protein biochemistry to novel immunotherapeutics. Int J Hyperthermia 2013 0.75