Published in Arch Intern Med on July 09, 2007
The science of stroke: mechanisms in search of treatments. Neuron (2010) 6.14
Measures of adiposity and risk of stroke in China: a result from the Kailuan study. PLoS One (2013) 1.25
Cardiovascular disease risk of abdominal obesity vs. metabolic abnormalities. Obesity (Silver Spring) (2010) 1.18
The role of bone marrow and visceral fat on bone metabolism. Curr Osteoporos Rep (2011) 1.16
Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization. Vasc Health Risk Manag (2010) 1.16
Adipose tissue: a motor for the inflammation associated with obesity. IUBMB Life (2009) 1.12
Estimation of the burden of cardiovascular disease attributable to modifiable risk factors and cost-effectiveness analysis of preventative interventions to reduce this burden in Argentina. BMC Public Health (2010) 1.08
Body mass index and the risk of dementia among Louisiana low income diabetic patients. PLoS One (2012) 1.07
The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection. Eur J Epidemiol (2013) 1.03
Race- and sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) study. Stroke (2010) 1.00
Cognitive function in morbidly obese individuals with and without binge eating disorder. Compr Psychiatry (2011) 0.97
Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther (2012) 0.96
Relationship between blood mercury concentration and waist-to-hip ratio in elderly Korean individuals living in coastal areas. J Prev Med Public Health (2011) 0.91
Stroke incidence and association with risk factors in women: a 32-year follow-up of the Prospective Population Study of Women in Gothenburg. BMJ Open (2014) 0.88
Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women. J Clin Endocrinol Metab (2009) 0.88
Hyperglycemia and stroke mortality: comparison between fasting and 2-h glucose criteria. Diabetes Care (2008) 0.85
Association between stroke and metabolic syndrome in a Japanese population: Jichi Medical School (JMS) Cohort Study. J Epidemiol (2009) 0.84
A comparison of the predictive power of anthropometric indices for hypertension and hypotension risk. PLoS One (2014) 0.82
Association between different obesity measures and the risk of stroke in the EPIC Spanish cohort. Eur J Nutr (2014) 0.80
Prevalence, incidence and concomitant co-morbidities of type 2 diabetes mellitus in South Western Germany--a retrospective cohort and case control study in claims data of a large statutory health insurance. BMC Public Health (2015) 0.80
Adiposity and ischemic and hemorrhagic stroke: Prospective study in women and meta-analysis. Neurology (2016) 0.80
The mediating effect of chronic pain on the relationship between obesity and physical function and disability in older adults. J Am Geriatr Soc (2013) 0.79
BMI and coronary heart disease risk among low-income and underinsured diabetic patients. Diabetes Care (2014) 0.77
Predictors of Treatment Response to Tesamorelin, a Growth Hormone-Releasing Factor Analog, in HIV-Infected Patients with Excess Abdominal Fat. PLoS One (2015) 0.77
Obesity and stroke: Can we translate from rodents to patients? J Cereb Blood Flow Metab (2016) 0.76
The Abundance of Epicardial Adipose Tissue Surrounding Left Atrium Is Associated With the Occurrence of Stroke in Patients With Atrial Fibrillation. Medicine (Baltimore) (2016) 0.76
Interactive effects of physical fitness and body mass index on risk of stroke: A national cohort study. Int J Stroke (2016) 0.76
Glucose regulation and cognitive function after bariatric surgery. J Clin Exp Neuropsychol (2015) 0.75
Statistical evaluation of adding multiple risk factors improves Framingham stroke risk score. BMC Med Res Methodol (2017) 0.75
Association with increased risk of stroke. Dtsch Arztebl Int (2010) 0.75
Waist to hip ratio as a supplement to body mass index. Arch Intern Med (2008) 0.75
Metabolic Syndrome and its Profound Effect on Prevalence of Ischemic Stroke. Am Med Stud Res J (2014) 0.75
Obesity paradox in stroke - Myth or reality? A systematic review. PLoS One (2017) 0.75
Obesity Disease and Surgery. Int J Chronic Dis (2014) 0.75
The Relationship between Metabolically Obese Non-Obese Weight and Stroke: The Korea National Health and Nutrition Examination Survey. PLoS One (2016) 0.75
Overweight, obesity, and risk of cardiometabolic multimorbidity: pooled analysis of individual-level data for 120 813 adults from 16 cohort studies from the USA and Europe. Lancet Public Health (2017) 0.75
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA (2002) 18.43
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature (2003) 13.00
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. Lancet (2006) 11.64
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA (2003) 9.06
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
The diabetes risk score: a practical tool to predict type 2 diabetes risk. Diabetes Care (2003) 7.74
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med (2014) 6.12
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
The burden of mortality attributable to diabetes: realistic estimates for the year 2000. Diabetes Care (2005) 5.80
The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care (2003) 5.48
Thirty-five-year trends in cardiovascular risk factors in Finland. Int J Epidemiol (2009) 5.37
European population substructure: clustering of northern and southern populations. PLoS Genet (2006) 5.27
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet (2008) 4.84
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study. Lancet (2008) 4.66
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurol (2006) 4.54
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol (2005) 4.49
Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study. Diabetes (2003) 4.44
Comparison of body mass index, waist circumference, and waist/hip ratio in predicting incident diabetes: a meta-analysis. Epidemiol Rev (2007) 4.43
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes (2008) 4.20
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol (2005) 3.95
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Age at initiation and frequency of screening to detect type 2 diabetes: a cost-effectiveness analysis. Lancet (2010) 3.92
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med (2004) 3.68
The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch Intern Med (2002) 3.61
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet (2011) 3.56
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci. PLoS Genet (2007) 3.47
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol (2008) 3.28
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care (2007) 3.10
Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. Eur Heart J (2006) 2.94
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Joint effects of physical activity, body mass index, waist circumference and waist-to-hip ratio with the risk of cardiovascular disease among middle-aged Finnish men and women. Eur Heart J (2004) 2.92
Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome. Diab Vasc Dis Res (2005) 2.91
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet (2013) 2.87
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study. Diabetes (2005) 2.82
The validity of the Finnish Hospital Discharge Register and Causes of Death Register data on coronary heart disease. Eur J Cardiovasc Prev Rehabil (2005) 2.78
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes (2006) 2.58
Lifestyle intervention for prevention of type 2 diabetes in primary health care: one-year follow-up of the Finnish National Diabetes Prevention Program (FIN-D2D). Diabetes Care (2010) 2.50
Type 2 diabetes and the risk of Parkinson's disease. Diabetes Care (2007) 2.48
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes (2004) 2.43
Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med (2002) 2.41
Prevalence of the metabolic syndrome among Omani adults. Diabetes Care (2003) 2.35
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study. Thromb Haemost (2006) 2.25
Metabonomic, transcriptomic, and genomic variation of a population cohort. Mol Syst Biol (2010) 2.17
Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr (2011) 2.16
Serum γ-glutamyltransferase and the risk of heart failure in men and women in Finland. Heart (2012) 2.10
Physical activity, body mass index, and risk of type 2 diabetes in patients with normal or impaired glucose regulation. Arch Intern Med (2004) 2.05
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes (2006) 2.03
Coffee consumption and risk of type 2 diabetes mellitus among middle-aged Finnish men and women. JAMA (2004) 2.03
Remapping the insulin gene/IDDM2 locus in type 1 diabetes. Diabetes (2004) 2.02