Published in Crit Care on January 01, 2007
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Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med (2014) 1.20
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Therapeutic endoscopy for acute upper gastrointestinal bleeding. Nat Rev Gastroenterol Hepatol (2010) 1.02
Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought. Pediatr Crit Care Med (2014) 1.00
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Before-after study of a standardized hospital order set for the management of septic shock. Crit Care Med (2006) 4.10
Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med (2001) 3.95
The epidemiology of the systemic inflammatory response. Intensive Care Med (2000) 3.67
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Early goal-directed therapy, corticosteroid, and recombinant human activated protein C for the treatment of severe sepsis and septic shock in the emergency department. Acad Emerg Med (2005) 2.46
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Influences on physicians' choices of intravenous colloids. Intensive Care Med (2002) 0.97
Sepsis: state of the art. Dis Mon (2001) 0.92
Equipment review: the success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation. Crit Care (2005) 0.88
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A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med (2013) 8.94
Randomized trials stopped early for benefit: a systematic review. JAMA (2005) 8.43
Transfusion strategies for patients in pediatric intensive care units. N Engl J Med (2007) 7.21
A guide for the design and conduct of self-administered surveys of clinicians. CMAJ (2008) 6.72
Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. JAMA (2012) 6.69
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
The need for an institute of continuing health education. CMAJ (2008) 6.36
Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data. CMAJ (2009) 6.27
Hypoglycemia and risk of death in critically ill patients. N Engl J Med (2012) 6.17
Hypothermia therapy after traumatic brain injury in children. N Engl J Med (2008) 6.10
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90
A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med (2006) 5.74
Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis. JAMA (2002) 5.57
Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2007) 5.51
An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations. Am J Respir Crit Care Med (2006) 5.29
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med (2008) 5.20
A systematic review and meta-analysis of studies comparing mortality rates of private for-profit and private not-for-profit hospitals. CMAJ (2002) 4.84
Does this patient have deep vein thrombosis? JAMA (2006) 4.44
Need for expertise based randomised controlled trials. BMJ (2005) 4.34
An observational study of orthopaedic abstracts and subsequent full-text publications. J Bone Joint Surg Am (2002) 4.25
Clinical trial registration--looking back and moving ahead. N Engl J Med (2007) 4.07
No more dithering on e-health: let's keep patients safe instead. CMAJ (2010) 4.01
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
Reliability of point-of-care testing for glucose measurement in critically ill adults. Crit Care Med (2005) 3.84
Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials. CMAJ (2007) 3.77
CONSORT 2010 changes and testing blindness in RCTs. Lancet (2010) 3.68
Clinical consequences of red cell storage in the critically ill. Transfusion (2006) 3.57
Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism? Ann Intern Med (2008) 3.56
The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med (2013) 3.43
Family satisfaction with care in the intensive care unit: results of a multiple center study. Crit Care Med (2002) 3.36
Barriers to full-text publication following presentation of abstracts at annual orthopaedic meetings. J Bone Joint Surg Am (2003) 3.36
Overdiagnosis of asthma in obese and nonobese adults. CMAJ (2008) 3.23
Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis. BMJ (2009) 3.22
Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15
Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review. Crit Care Med (2011) 3.07
Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med (2006) 3.06
The H1N1 vaccine race: can we beat the pandemic? CMAJ (2009) 3.01
Methodologic issues in systematic reviews and meta-analyses. Clin Orthop Relat Res (2003) 2.90
Rationing critical care beds: a systematic review. Crit Care Med (2004) 2.86
Binge drinking: all too prevalent and hazardous. CMAJ (2011) 2.85
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med (2015) 2.85
Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids. Crit Care Med (2010) 2.82
Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest (2006) 2.79
The Very Elderly Admitted to ICU: A Quality Finish? Crit Care Med (2015) 2.77
Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock. Crit Care Med (2009) 2.77
Is it time for another medical curriculum revolution? CMAJ (2008) 2.76
Payments for care at private for-profit and private not-for-profit hospitals: a systematic review and meta-analysis. CMAJ (2004) 2.76
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One (2012) 2.75
Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions. JAMA (2003) 2.74
Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review. JAMA (2003) 2.73
One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med (2016) 2.73
Acute rehabilitation practices in critically ill children: a multicenter study. Pediatr Crit Care Med (2014) 2.71
Clinician predictions of intensive care unit mortality. Crit Care Med (2004) 2.65
End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61
Frequency of colorectal cancer screening and the impact of family physicians on screening behaviour. CMAJ (2007) 2.60
Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med (2011) 2.59
Age of transfused blood in critically ill adults. N Engl J Med (2015) 2.52
Uniform format for disclosure of competing interests in ICMJE journals. N Engl J Med (2009) 2.46
Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ (2007) 2.44
Preservation of renal function following partial or radical nephrectomy using 24-hour creatinine clearance. Eur Urol (2008) 2.43
Measuring performance is essential to patient-centred care. CMAJ (2010) 2.42
The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med (2009) 2.38
Nonleg venous thrombosis in critically ill adults: a nested prospective cohort study. JAMA Intern Med (2014) 2.36
The need for public engagement in choosing health priorities. CMAJ (2010) 2.35
Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest (2004) 2.35
Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med (2011) 2.35
Early intravenous unfractionated heparin and mortality in septic shock. Crit Care Med (2008) 2.35
Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ (2007) 2.33
Treatment of new-onset atrial fibrillation in noncardiac intensive care unit patients: a systematic review of randomized controlled trials. Crit Care Med (2008) 2.33
Mortality predictions in the intensive care unit: comparing physicians with scoring systems. Crit Care Med (2006) 2.29
Written informed consent and selection bias in observational studies using medical records: systematic review. BMJ (2009) 2.27
A systematic review of studies comparing health outcomes in Canada and the United States. Open Med (2007) 2.26
Dying in the ICU: perspectives of family members. Chest (2003) 2.25
Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest (2013) 2.24
Can erythropoietin eradicate red cell transfusions in the critically ill? Crit Care Med (2006) 2.21