Published in RNA on July 24, 2007
PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Mol Cell (2008) 4.48
MicroRNA assassins: factors that regulate the disappearance of miRNAs. Nat Struct Mol Biol (2010) 2.42
Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation. J Virol (2007) 1.90
RNA granules in germ cells. Cold Spring Harb Perspect Biol (2011) 1.80
2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA (2009) 1.76
Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis. Nat Struct Mol Biol (2012) 1.70
Widespread expression of piRNA-like molecules in somatic tissues. Nucleic Acids Res (2011) 1.56
Small RNA metabolism in Arabidopsis. Trends Plant Sci (2008) 1.56
Hen1 is required for oocyte development and piRNA stability in zebrafish. EMBO J (2010) 1.53
HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse. PLoS Genet (2015) 1.49
Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells. BMC Mol Biol (2009) 1.42
Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo. PLoS Pathog (2012) 1.40
The Arabidopsis nucleotidyl transferase HESO1 uridylates unmethylated small RNAs to trigger their degradation. Curr Biol (2012) 1.40
Technical variables in high-throughput miRNA expression profiling: much work remains to be done. Biochim Biophys Acta (2008) 1.36
Computational analysis of mouse piRNA sequence and biogenesis. PLoS Comput Biol (2007) 1.36
Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature (2009) 1.34
Regulation of small RNA stability: methylation and beyond. Cell Res (2012) 1.33
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans. PLoS Genet (2012) 1.20
Argonautes confront new small RNAs. Curr Opin Chem Biol (2007) 1.20
Uridylation of miRNAs by hen1 suppressor1 in Arabidopsis. Curr Biol (2012) 1.19
PIWI Expression and Function in Cancer. Front Genet (2012) 1.12
The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs. PLoS Genet (2012) 1.12
Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. RNA (2009) 1.09
Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase. RNA (2011) 0.97
The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing. Nucleic Acids Res (2010) 0.96
Posttranscriptional regulation of gene expression by Piwi proteins and piRNAs. Mol Cell (2014) 0.96
WAVY LEAF1, an ortholog of Arabidopsis HEN1, regulates shoot development by maintaining MicroRNA and trans-acting small interfering RNA accumulation in rice. Plant Physiol (2010) 0.93
Minireview: The roles of small RNA pathways in reproductive medicine. Mol Endocrinol (2011) 0.92
PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression. Natl Sci Rev (2014) 0.92
Mechanisms that impact microRNA stability in plants. RNA Biol (2012) 0.91
Identification and Functional Analysis of the Pre-piRNA 3' Trimmer in Silkworms. Cell (2016) 0.90
Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol (2016) 0.90
Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila. Genes Dev (2014) 0.88
The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev (2015) 0.88
Elements and machinery of non-coding RNAs: toward their taxonomy. EMBO Rep (2014) 0.88
DNA rearrangements directed by non-coding RNAs in ciliates. Wiley Interdiscip Rev RNA (2011) 0.88
Inhibition of 3' modification of small RNAs in virus-infected plants require spatial and temporal co-expression of small RNAs and viral silencing-suppressor proteins. Nucleic Acids Res (2008) 0.87
Developmentally programmed, RNA-directed genome rearrangement in Tetrahymena. Dev Growth Differ (2011) 0.85
piRNAs from Pig Testis Provide Evidence for a Conserved Role of the Piwi Pathway in Post-Transcriptional Gene Regulation in Mammals. PLoS One (2015) 0.84
The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway. Mol Microbiol (2012) 0.83
The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry. RNA Biol (2014) 0.83
Rapid evolution of piRNA pathway in the teleost fish: implication for an adaptation to transposon diversity. Genome Biol Evol (2014) 0.82
Mechanisms of microRNA turnover. Curr Opin Plant Biol (2015) 0.82
Synergistic and independent actions of multiple terminal nucleotidyl transferases in the 3' tailing of small RNAs in Arabidopsis. PLoS Genet (2015) 0.81
Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline. Semin Cell Dev Biol (2016) 0.81
Small RNAs meet their targets: when methylation defends miRNAs from uridylation. RNA Biol (2014) 0.80
Biogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biology. Int J Mol Sci (2012) 0.79
Profiling sex-specific piRNAs in zebrafish. Genetics (2010) 0.78
Characterization of Sus scrofa small non-coding RNAs present in both female and male gonads. PLoS One (2014) 0.76
Role of the Trypanosoma brucei HEN1 family methyltransferase in small interfering RNA modification. Eukaryot Cell (2013) 0.76
Kc167, a widely used Drosophila cell line, contains an active primary piRNA pathway. RNA (2016) 0.76
Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells. Sci Rep (2017) 0.75
Uridylation and adenylation of RNAs. Sci China Life Sci (2015) 0.75
Artificial "ping-pong" cascade of PIWI-interacting RNA in silkworm cells. RNA (2016) 0.75
High-throughput and site-specific identification of 2'-O methylation sites using ribose oxidation sequencing (RibOxi-seq). RNA (2017) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev (2001) 26.16
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr Biol (2002) 15.13
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
A distinct small RNA pathway silences selfish genetic elements in the germline. Science (2006) 11.63
The small RNA profile during Drosophila melanogaster development. Dev Cell (2003) 11.46
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol (2007) 9.65
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature (2004) 7.63
The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev (2002) 7.61
Methylation as a crucial step in plant microRNA biogenesis. Science (2005) 7.16
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol (2005) 5.99
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol (2007) 5.35
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends. Genes Dev (2007) 4.68
HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3' terminal nucleotide. Nucleic Acids Res (2006) 3.14
Mighty Piwis defend the germline against genome intruders. Cell (2007) 3.06
Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene. Genetics (2004) 2.99
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini. Nat Struct Mol Biol (2007) 2.89
A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. J Virol (2006) 2.87
The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated. Nat Struct Mol Biol (2007) 2.71
Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes. Genes Dev (2006) 2.17
A combined computational-experimental approach predicts human microRNA targets. Genes Dev (2004) 9.82
Numerous microRNPs in neuronal cells containing novel microRNAs. RNA (2003) 6.28
Microarray-based, high-throughput gene expression profiling of microRNAs. Nat Methods (2004) 5.45
RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA (2005) 4.91
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev (2005) 4.55
An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell (2007) 4.03
The microRNA world: small is mighty. Trends Biochem Sci (2003) 3.86
miRNP:mRNA association in polyribosomes in a human neuronal cell line. RNA (2004) 3.39
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. Nat Genet (2010) 3.24
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini. Nat Struct Mol Biol (2007) 2.89
A yeast functional screen predicts new candidate ALS disease genes. Proc Natl Acad Sci U S A (2011) 2.68
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol (2009) 2.42
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. J Biol Chem (2001) 2.25
A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells. RNA (2007) 2.13
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J (2006) 1.95
Precursor microRNA-programmed silencing complex assembly pathways in mammals. Mol Cell (2012) 1.81
Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis. Nat Struct Mol Biol (2012) 1.70
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum Mol Genet (2012) 1.62
MicroRNAs: biogenesis and molecular functions. Brain Pathol (2008) 1.60
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA (2009) 1.53
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA (2009) 1.48
Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein. RNA (2005) 1.45
Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment. Nat Protoc (2010) 1.41
Site-specific crosslinking of human microRNPs to RNA targets. RNA (2008) 1.35
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding. J Biol Chem (2008) 1.30
Immunoprecipitation of microRNPs and directional cloning of microRNAs. Methods Mol Biol (2005) 1.25
Arginine methylation of vasa protein is conserved across phyla. J Biol Chem (2010) 1.21
PIWI Expression and Function in Cancer. Front Genet (2012) 1.12
Detection of microRNAs and assays to monitor microRNA activities in vivo and in vitro. Methods Mol Biol (2005) 1.12
Neurological manifestations of Behçet's disease in Japan: a study of 54 patients. J Neurol (2010) 1.11
Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. Cancer Sci (2010) 1.10
Small RNAs: The seeds of silence. Nature (2008) 1.10
Transfer RNA as a source of small functional RNA. J Mol Biol Mol Imaging (2015) 1.08
Mitochondrial protein BmPAPI modulates the length of mature piRNAs. RNA (2013) 1.07
Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways. Arthritis Rheum (2012) 1.06
Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery. Hum Mol Genet (2009) 1.02
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns. RNA (2013) 1.01
Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis. Arthritis Rheum (2006) 0.98
Reversible infantile respiratory chain deficiency: a clinical and molecular study. Ann Neurol (2010) 0.95
Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases. FEBS Lett (2005) 0.95
Screening of tuberculosis by interferon-gamma assay before biologic therapy for rheumatoid arthritis. Tuberculosis (Edinb) (2009) 0.93
Heme oxygenase 1 attenuates the development of atopic dermatitis-like lesions in mice: implications for human disease. J Allergy Clin Immunol (2008) 0.93
2'-O-methyl modification in mouse piRNAs and its methylase. Nucleic Acids Symp Ser (Oxf) (2007) 0.91
Mitochondrial tRNA-lookalikes in nuclear chromosomes: could they be functional? RNA Biol (2015) 0.88
High-throughput experimental studies to identify miRNA targets directly, with special focus on the mammalian brain. Brain Res (2010) 0.86
Serum HO-1 is useful to make differential diagnosis of secondary hemophagocytic syndrome from other similar hematological conditions. Int J Hematol (2010) 0.85
Therapeutic angiogenesis in patients with systemic sclerosis by autologous transplantation of bone-marrow-derived cells. Mod Rheumatol (2010) 0.84
Identification of in vivo, conserved, TAF15 RNA binding sites reveals the impact of TAF15 on the neuronal transcriptome. Cell Rep (2013) 0.83
Circulating carbon monoxide level is elevated after sleep in patients with obstructive sleep apnea. Chest (2008) 0.82
RNA dysregulation in diseases of motor neurons. Annu Rev Pathol (2011) 0.81
Immunoprecipitation of piRNPs and directional, next generation sequencing of piRNAs. Methods Mol Biol (2011) 0.81
HITS-CLIP (CLIP-Seq) for mouse Piwi proteins. Methods Mol Biol (2014) 0.81
Elective affinities: a Tudor-Aubergine tale of germline partnership. Genes Dev (2010) 0.81
MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS. Brain Pathol (2011) 0.81
Four-leaf clover qRT-PCR: A convenient method for selective quantification of mature tRNA. RNA Biol (2015) 0.80
Asymmetric bilateral demyelinating optic neuropathy from tacrolimus toxicity. J Neurol Sci (2010) 0.79
Decoding property of C5 uridine modification at the wobble position of tRNA anticodon. Nucleic Acids Res Suppl (2003) 0.76
Analysis of sDMA modifications of PIWI proteins. Methods Mol Biol (2014) 0.76
A novel 8-joint ultrasound score is useful in daily practice for rheumatoid arthritis. Mod Rheumatol (2014) 0.75
Systemic sclerosis and pseudomesotheliomatous adenocarcinoma of the lung. Mod Rheumatol (2006) 0.75
[Liver involvement in primary Sjogren's syndrome]. Nihon Rinsho Meneki Gakkai Kaishi (2004) 0.75
Ultrasonography predicts achievement of Boolean remission after DAS28-based clinical remission of rheumatoid arthritis. Mod Rheumatol (2013) 0.75
Native gel analysis for mammalian microRNPs assembled from pre-microRNAs. Methods Mol Biol (2015) 0.75
Non-IgG4-related Multifocal Fibrosclerosis. Intern Med (2016) 0.75