Published in Endocr Dev on January 01, 2007
Biological roles for the NOX family NADPH oxidases. J Biol Chem (2008) 1.96
NOX enzymes as novel targets for drug development. Semin Immunopathol (2008) 1.90
Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation. J Biol Chem (2009) 1.29
European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. J Clin Endocrinol Metab (2014) 1.26
Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract. Semin Immunopathol (2008) 1.11
Nox enzymes in immune cells. Semin Immunopathol (2008) 1.01
Detection and treatment of congenital hypothyroidism. Nat Rev Endocrinol (2011) 0.95
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs. PLoS One (2013) 0.89
KCNE2 and the K (+) channel: the tail wagging the dog. Channels (Austin) (2012) 0.84
Role of the NADPH Oxidases DUOX and NOX4 in Thyroid Oxidative Stress. Eur Thyroid J (2013) 0.80
Sonographic evaluation of children with congenital hypothyroidism. Radiol Bras (2015) 0.79
Permanent and Transient Congenital Hypothyroidism in Hamadan West Province of Iran. Int J Endocrinol Metab (2016) 0.78
DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ. Eur Thyroid J (2015) 0.75
Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation. Lancet (2004) 2.98
Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J Biol Chem (2003) 2.71
Thyroid hormone concentrations, disease, physical function, and mortality in elderly men. J Clin Endocrinol Metab (2005) 2.35
Localisation and mechanism of renal retention of radiolabelled somatostatin analogues. Eur J Nucl Med Mol Imaging (2005) 2.26
The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. Endocrinology (2005) 2.14
Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction. Endocrinology (2007) 2.06
Mutations in the iodotyrosine deiodinase gene and hypothyroidism. N Engl J Med (2008) 2.06
Iodothyronine levels in the human developing brain: major regulatory roles of iodothyronine deiodinases in different areas. J Clin Endocrinol Metab (2004) 1.95
Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the generation R study. J Clin Endocrinol Metab (2010) 1.93
Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects. J Clin Endocrinol Metab (2003) 1.86
Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. J Clin Invest (2007) 1.80
Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. J Clin Endocrinol Metab (2010) 1.72
Minireview: thyroid hormone transporters: the knowns and the unknowns. Mol Endocrinol (2010) 1.67
Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study. Toxicology (2007) 1.63
Maternal thyroid autoimmunity during pregnancy and the risk of attention deficit/hyperactivity problems in children: the Generation R Study. Thyroid (2011) 1.61
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet (2008) 1.60
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. J Clin Endocrinol Metab (2003) 1.50
A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). Toxicol Lett (2008) 1.48
Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology (2011) 1.47
Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. Mol Endocrinol (2008) 1.44
Clinical phenotype and mutant TRα1. N Engl J Med (2012) 1.43
Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats. J Clin Invest (2008) 1.43
Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study. J Clin Endocrinol Metab (2014) 1.40
High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study. Arch Intern Med (2008) 1.39
Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities. J Clin Endocrinol Metab (2005) 1.37
Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities. Eur J Nucl Med Mol Imaging (2003) 1.34
Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism. Mol Endocrinol (2006) 1.33
Thyroid hormone transport in and out of cells. Trends Endocrinol Metab (2008) 1.32
Maternal thyroid function during pregnancy and behavioral problems in the offspring: the generation R study. Pediatr Res (2011) 1.27
Induction of thyroid hormone-degrading deiodinase in cardiac hypertrophy and failure. Endocrinology (2002) 1.25
Genetics and phenomics of thyroid hormone transport by MCT8. Mol Cell Endocrinol (2010) 1.25
Minireview: Pathophysiological importance of thyroid hormone transporters. Endocrinology (2009) 1.25
Effects of serum TSH and FT4 levels and the TSHR-Asp727Glu polymorphism on bone: the Rotterdam Study. Clin Endocrinol (Oxf) (2007) 1.25
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). Mol Nutr Food Res (2008) 1.23
Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients. Clin Endocrinol (Oxf) (2007) 1.22
Identification and functional characterization of zebrafish solute carrier Slc16a2 (Mct8) as a thyroid hormone membrane transporter. Endocrinology (2011) 1.20
A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice. Environ Health Perspect (2007) 1.19
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. J Clin Endocrinol Metab (2002) 1.16
A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine. J Clin Endocrinol Metab (2008) 1.15
Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases. Eur J Endocrinol (2006) 1.14
Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts. J Clin Endocrinol Metab (2009) 1.14
Thyroid hormone transporters. Vitam Horm (2005) 1.13
Consequences of monocarboxylate transporter 8 deficiency for renal transport and metabolism of thyroid hormones in mice. Endocrinology (2009) 1.13
Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference. Endocrinology (2003) 1.12
Large induction of type III deiodinase expression after partial hepatectomy in the regenerating mouse and rat liver. Endocrinology (2008) 1.12
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet (2013) 1.12
Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain. Endocrinology (2012) 1.09
Left-ventricular remodeling after myocardial infarction is associated with a cardiomyocyte-specific hypothyroid condition. Endocrinology (2010) 1.09
Biochemical mechanisms of thyroid hormone deiodination. Thyroid (2005) 1.08
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression. J Clin Endocrinol Metab (2011) 1.08
Impact of monocarboxylate transporter-8 deficiency on the hypothalamus-pituitary-thyroid axis in mice. Endocrinology (2010) 1.08
The impact of a TSH receptor gene polymorphism on thyroid-related phenotypes in a healthy Danish twin population. Clin Endocrinol (Oxf) (2007) 1.08
A 28-day oral dose toxicity study enhanced to detect endocrine effects of hexabromocyclododecane in Wistar rats. Toxicol Sci (2006) 1.07
The type II iodothyronine deiodinase is up-regulated in skeletal muscle during prolonged critical illness. J Clin Endocrinol Metab (2007) 1.06
Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism. Mol Endocrinol (2004) 1.05
Neuroanatomical pathways for thyroid hormone feedback in the human hypothalamus. J Clin Endocrinol Metab (2005) 1.05
The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. J Clin Endocrinol Metab (2006) 1.04
A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. Am J Physiol Endocrinol Metab (2005) 1.04
Thyroid hormones, dementia, and atrophy of the medial temporal lobe. J Clin Endocrinol Metab (2006) 1.03
A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. Eur J Endocrinol (2011) 1.03
Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study. J Clin Endocrinol Metab (2012) 1.03
Thyroid hormone transporters in health and disease. Thyroid (2005) 1.02
A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats. Toxicology (2007) 1.02
Genotype-phenotype relationship in patients with mutations in thyroid hormone transporter MCT8. Endocrinology (2008) 1.02
Human fetal and cord serum thyroid hormones: developmental trends and interrelationships. J Clin Endocrinol Metab (2004) 1.01
Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters. J Mol Endocrinol (2009) 1.00
Deiodinase activity is present in Xenopus laevis during early embryogenesis. Endocrinology (2006) 0.99
Clinical phenotype of a new type of thyroid hormone resistance caused by a mutation of the TRα1 receptor: consequences of LT4 treatment. J Clin Endocrinol Metab (2013) 0.99
Mechanisms of disease: psychomotor retardation and high T3 levels caused by mutations in monocarboxylate transporter 8. Nat Clin Pract Endocrinol Metab (2006) 0.99
Preclinical comparison of (111)In-labeled DTPA- or DOTA-bombesin analogs for receptor-targeted scintigraphy and radionuclide therapy. J Nucl Med (2002) 0.99
Thyroid hormone transport by monocarboxylate transporters. Best Pract Res Clin Endocrinol Metab (2007) 0.98
Functional analysis of monocarboxylate transporter 8 mutations identified in patients with X-linked psychomotor retardation and elevated serum triiodothyronine. J Clin Endocrinol Metab (2007) 0.98
Thyroid hormone independent associations between serum TSH levels and indicators of bone turnover in cured patients with differentiated thyroid carcinoma. Eur J Endocrinol (2008) 0.97
Tissue thyroid hormone levels in critical illness. J Clin Endocrinol Metab (2005) 0.96
Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children. J Nutr (2012) 0.96
Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial. Arch Intern Med (2010) 0.96
Psychological well-being correlates with free thyroxine but not free 3,5,3'-triiodothyronine levels in patients on thyroid hormone replacement. J Clin Endocrinol Metab (2006) 0.96
Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism. Endocrinology (2008) 0.95
Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis. J Clin Invest (2014) 0.95
Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting. J Clin Endocrinol Metab (2009) 0.95
Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes. Thyroid (2008) 0.94
Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism. Endocrinology (2003) 0.94
Changes within the thyroid axis during the course of critical illness. Endocrinol Metab Clin North Am (2006) 0.93
Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency. Endocrinology (2013) 0.93
Identification, functional analysis, prevalence and treatment of monocarboxylate transporter 8 (MCT8) mutations in a cohort of adult patients with mental retardation. Clin Endocrinol (Oxf) (2013) 0.93
Identification of molecular mechanisms related to nonthyroidal illness syndrome in skeletal muscle and adipose tissue from patients with septic shock. Clin Endocrinol (Oxf) (2007) 0.93
Serum thyroid hormones in preterm infants: associations with postnatal illnesses and drug usage. J Clin Endocrinol Metab (2005) 0.93
Changes within the thyroid axis during critical illness. Crit Care Clin (2006) 0.93
Sorafenib induced thyroiditis in two patients with hepatocellular carcinoma. Thyroid (2011) 0.93
Developmental trends in cord and postpartum serum thyroid hormones in preterm infants. J Clin Endocrinol Metab (2004) 0.92
Early expression of thyroid hormone deiodinases and receptors in human fetal cerebral cortex. Brain Res Dev Brain Res (2002) 0.92
Novel pathogenic mechanism suggested by ex vivo analysis of MCT8 (SLC16A2) mutations. Hum Mutat (2009) 0.92
The pathophysiological consequences of thyroid hormone transporter deficiencies: Insights from mouse models. Biochim Biophys Acta (2012) 0.92
Serum thyroid hormones in preterm infants and relationships to indices of severity of intercurrent illness. J Clin Endocrinol Metab (2004) 0.92
Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study. J Clin Endocrinol Metab (2013) 0.92
Polymorphisms in the brain-specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients. Clin Endocrinol (Oxf) (2008) 0.91
Regulation of type III iodothyronine deiodinase expression in human cell lines. Endocrinology (2006) 0.91
Type 3 deiodinase is highly expressed in infiltrating neutrophilic granulocytes in response to acute bacterial infection. Thyroid (2008) 0.91
Iodothyronine deiodinase enzyme activities in bone. Bone (2008) 0.91