Peter Parham

Author PubWeight™ 164.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A human genome diversity cell line panel. Science 2002 14.11
2 Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet 2007 6.83
3 IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex. Nucleic Acids Res 2003 5.64
4 Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood 2010 4.46
5 KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu Rev Immunol 2001 4.24
6 The IMGT/HLA database. Nucleic Acids Res 2012 3.61
7 Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A 2011 3.53
8 Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function. J Exp Med 2006 3.50
9 Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry. Sci Transl Med 2013 3.41
10 Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood 2008 3.18
11 The IMGT/HLA database. Nucleic Acids Res 2010 2.89
12 Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3. J Immunol 2008 2.76
13 MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response. Blood 2008 2.71
14 The shaping of modern human immune systems by multiregional admixture with archaic humans. Science 2011 2.63
15 A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature. Blood 2007 2.39
16 Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT. Blood 2007 2.36
17 Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans. Nat Genet 2007 2.36
18 Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B. J Immunol 2007 2.28
19 Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues. J Exp Med 2005 2.23
20 The IMGT/HLA database. Nucleic Acids Res 2008 2.22
21 Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation. Blood 2003 2.08
22 KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand. J Immunol 2005 2.07
23 Genetic control of human NK cell repertoire. J Immunol 2002 2.01
24 KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. J Exp Med 2009 1.99
25 Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells. J Immunol 2007 1.94
26 The protein made from a common allele of KIR3DL1 (3DL1*004) is poorly expressed at cell surfaces due to substitution at positions 86 in Ig domain 0 and 182 in Ig domain 1. J Immunol 2003 1.89
27 Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype. J Immunol 2002 1.79
28 NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection. J Immunol 2007 1.78
29 Reconstructing the population genetic history of the Caribbean. PLoS Genet 2013 1.68
30 Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus. PLoS One 2010 1.62
31 Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates. Genome Res 2005 1.56
32 T cell-dependent production of IFN-gamma by NK cells in response to influenza A virus. J Clin Invest 2004 1.56
33 Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes. J Immunol 2003 1.52
34 Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit Rev Immunol 2002 1.52
35 Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression. Immunogenetics 2002 1.51
36 Domain shuffling has been the main mechanism forming new hominoid killer cell Ig-like receptors. J Immunol 2004 1.51
37 Donor-recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell transplantation. Hum Immunol 2007 1.43
38 Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes. Genome Res 2009 1.42
39 Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics 2002 1.37
40 Stress management: MHC class I and class I-like molecules as reporters of cellular stress. Immunity 2003 1.36
41 Mini-review: defense strategies and immunity-related genes. Eur J Immunol 2004 1.35
42 Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc Natl Acad Sci U S A 2009 1.35
43 Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402. J Immunol 2009 1.32
44 NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C. J Immunol 2002 1.32
45 Distinctive KIR and HLA diversity in a panel of north Indian Hindus. Immunogenetics 2002 1.32
46 Evolution of killer cell Ig-like receptor (KIR) genes: definition of an orangutan KIR haplotype reveals expansion of lineage III KIR associated with the emergence of MHC-C. J Immunol 2007 1.28
47 Variable receptors controlling activation and inhibition of NK cells. Curr Opin Immunol 2002 1.26
48 Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B. Immunogenetics 2002 1.22
49 Conservation and variation in human and common chimpanzee CD94 and NKG2 genes. J Immunol 2002 1.21
50 Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I. J Immunol 2010 1.20
51 Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia. J Immunol 2014 1.20
52 Complex interactions: the immunogenetics of human leukocyte antigen and killer cell immunoglobulin-like receptors. Semin Hematol 2005 1.19
53 Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1. J Immunol 2008 1.19
54 The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer. J Exp Med 2002 1.19
55 Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3. J Immunol 2012 1.19
56 High-throughput killer cell immunoglobulin-like receptor genotyping by MALDI-TOF mass spectrometry with discovery of novel alleles. Immunogenetics 2007 1.17
57 High KIR diversity in Amerindians is maintained using few gene-content haplotypes. Immunogenetics 2006 1.17
58 Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells. PLoS Genet 2010 1.16
59 Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002. Immunogenetics 2003 1.16
60 The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates. Immunogenetics 2007 1.15
61 Nomenclature for Factors of the HLA System, 2004. Hum Immunol 2005 1.14
62 Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation? J Immunol 2008 1.13
63 Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes. J Immunol 2009 1.12
64 Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells. J Immunol 2010 1.09
65 Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans. PLoS Genet 2013 1.08
66 NK cells--from bench to clinic. Biol Blood Marrow Transplant 2012 1.08
67 Single-cell analysis of the human NK cell response to missing self and its inhibition by HLA class I. Blood 2004 1.06
68 Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution. Proc Natl Acad Sci U S A 2005 1.03
69 Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA. PLoS Pathog 2012 1.02
70 Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002. Hum Immunol 2003 1.00
71 A small, variable, and irregular killer cell Ig-like receptor locus accompanies the absence of MHC-C and MHC-G in gibbons. J Immunol 2009 1.00
72 Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3. Front Immunol 2012 0.99
73 Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. BMC Genomics 2011 0.99
74 Evolution and survival of marine carnivores did not require a diversity of killer cell Ig-like receptors or Ly49 NK cell receptors. J Immunol 2009 0.98
75 Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention. J Immunol 2010 0.95
76 The inhibitory receptor NKG2A determines lysis of vaccinia virus-infected autologous targets by NK cells. J Immunol 2006 0.94
77 Rhesus macaque KIR bind human MHC class I with broad specificity and recognize HLA-C more effectively than HLA-A and HLA-B. Immunogenetics 2011 0.93
78 Episodes of natural selection shaped the interactions of IgA-Fc with FcalphaRI and bacterial decoy proteins. J Immunol 2007 0.92
79 Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals. J Immunol 2009 0.91
80 Killer cell immunoglobulin-like receptor workshop: insights into evolution, genetics, function, and translation. Immunity 2011 0.88
81 NK cell-mediated lysis of autologous HCMV-infected skin fibroblasts is highly variable among NK cell clones and polyclonal NK cell lines. Clin Immunol 2002 0.88
82 Nomenclature for factors of the HLA system, 2002. Hum Immunol 2002 0.88
83 Exome capture from saliva produces high quality genomic and metagenomic data. BMC Genomics 2014 0.86
84 Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires. J Immunol 2011 0.84
85 Computational analyses of an evolutionary arms race between mammalian immunity mediated by immunoglobulin A and its subversion by bacterial pathogens. PLoS One 2013 0.82
86 KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand. Immunogenetics 2014 0.81
87 Nomenclature for factors of the HLA system, 2002. Eur J Immunogenet 2002 0.81
88 Do NK-cell receptors and alloreactivity affect solid organ transplantation? Transpl Immunol 2006 0.81
89 Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I. Immunogenetics 2011 0.81
90 Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines. Immunogenetics 2015 0.81
91 Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism. Immunogenetics 2012 0.80
92 The beta 2-microglobulin locus of rainbow trout (Oncorhynchus mykiss) contains three polymorphic genes. J Immunol 2004 0.79
93 High diversity of MIC genes in non-human primates. Immunogenetics 2014 0.78
94 Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes). Immunogenetics 2002 0.77
95 The evolution of NK cell diversity. Semin Immunol 2008 0.76
96 Structures of two major histocompatibility complex class I genes of the rainbow trout (Oncorhynchus mykiss). Immunogenetics 2002 0.76
97 Immunology: adaptable innate killers. Nature 2006 0.75