PubRank

Nikolaus Pfanner

Author PubWeight™ 149.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Importing mitochondrial proteins: machineries and mechanisms. Cell 2009 5.46
2 The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 2003 5.13
3 Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature 2003 3.46
4 Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell 2008 2.97
5 Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 2006 2.92
6 Mitochondrial protein import: from proteomics to functional mechanisms. Nat Rev Mol Cell Biol 2010 2.87
7 Mitochondrial import and the twin-pore translocase. Nat Rev Mol Cell Biol 2004 2.78
8 An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem 2003 2.59
9 Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell 2011 2.52
10 Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 2005 2.49
11 Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 2004 2.43
12 Multiple pathways for sorting mitochondrial precursor proteins. EMBO Rep 2008 2.19
13 Isolation of yeast mitochondria. Methods Mol Biol 2006 2.09
14 The protein import machinery of mitochondria. J Biol Chem 2004 2.02
15 The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell 2004 1.98
16 Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell 2009 1.96
17 The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell 2002 1.95
18 Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J 2005 1.92
19 Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science 2003 1.89
20 Mechanisms of protein import into mitochondria. Curr Biol 2003 1.76
21 Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 2006 1.75
22 A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol 2003 1.71
23 Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol 2007 1.64
24 Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol 2004 1.63
25 Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol 2009 1.62
26 Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains. J Mol Biol 2012 1.61
27 The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J 2007 1.58
28 Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway. J Biol Chem 2004 1.55
29 Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 2006 1.55
30 Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway. J Mol Biol 2006 1.53
31 Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour. J Mol Biol 2003 1.43
32 Regulation of mitochondrial protein import by cytosolic kinases. Cell 2011 1.42
33 The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins. J Mol Biol 2005 1.40
34 Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem 2004 1.37
35 Role of MINOS in mitochondrial membrane architecture and biogenesis. Trends Cell Biol 2012 1.36
36 Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J Cell Biol 2007 1.36
37 Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol 2005 1.34
38 The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem 2004 1.34
39 Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 2007 1.33
40 The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol 2008 1.32
41 A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 2006 1.32
42 Import of proteins into mitochondria. Methods Cell Biol 2007 1.30
43 Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase. J Cell Biol 2008 1.28
44 Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40. J Biol Chem 2007 1.27
45 Cooperation of translocase complexes in mitochondrial protein import. J Cell Biol 2007 1.26
46 Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10. J Biol Chem 2006 1.24
47 The mitochondrial proteome: from inventory to function. Cell 2008 1.23
48 Mitochondrial protein import: from transport pathways to an integrated network. Trends Biochem Sci 2011 1.23
49 Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins. J Cell Biol 2007 1.22
50 Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space. Mol Biol Cell 2007 1.22
51 Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 2003 1.21
52 Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex. Mol Cell Biol 2002 1.19
53 Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol 2005 1.16
54 Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem 2007 1.15
55 Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol 2003 1.14
56 Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane. Mol Cell 2011 1.14
57 Protein translocase of the outer mitochondrial membrane: role of import receptors in the structural organization of the TOM complex. J Mol Biol 2002 1.12
58 Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol 2010 1.11
59 Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell 2013 1.11
60 Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel. Mol Cell 2002 1.11
61 A dynamic machinery for import of mitochondrial precursor proteins. FEBS Lett 2007 1.10
62 Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes. J Mol Biol 2012 1.10
63 Mitofilin complexes: conserved organizers of mitochondrial membrane architecture. Biol Chem 2012 1.06
64 Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex. Mol Cell Biol 2003 1.05
65 The MIA system for protein import into the mitochondrial intermembrane space. Biochim Biophys Acta 2007 1.05
66 Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase. Mol Biol Cell 2008 1.04
67 The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol 2011 1.03
68 Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40. J Biol Chem 2008 1.01
69 Two modular forms of the mitochondrial sorting and assembly machinery are involved in biogenesis of alpha-helical outer membrane proteins. J Mol Biol 2009 1.01
70 The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes. EMBO Rep 2006 1.00
71 Preprotein translocase of the outer mitochondrial membrane: reconstituted Tom40 forms a characteristic TOM pore. J Mol Biol 2005 1.00
72 Biogenesis of mitochondrial membrane proteins. Curr Opin Cell Biol 2009 1.00
73 Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell 2011 0.97
74 Mitochondrial morphology and protein import--a tight connection? Biochim Biophys Acta 2006 0.97
75 Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane. Mol Biol Cell 2012 0.96
76 Powering mitochondrial protein import. Nat Struct Biol 2002 0.96
77 Cooperation of stop-transfer and conservative sorting mechanisms in mitochondrial protein transport. Curr Biol 2010 0.94
78 How mitochondria import hydrophilic and hydrophobic proteins. Trends Cell Biol 2002 0.92
79 Diverse mechanisms and machineries for import of mitochondrial proteins. Biol Chem 2007 0.92
80 Import of precursor proteins into isolated yeast mitochondria. Methods Mol Biol 2006 0.92
81 Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol 2012 0.91
82 Biochemistry. Assembling the outer membrane. Science 2010 0.91
83 Mechanisms of protein sorting in mitochondria. Cold Spring Harb Perspect Biol 2012 0.91
84 Biogenesis of mitochondria: dual role of Tom7 in modulating assembly of the preprotein translocase of the outer membrane. J Mol Biol 2010 0.90
85 Mitochondrial protein import machineries and lipids: a functional connection. Biochim Biophys Acta 2010 0.90
86 Chaperoning through the mitochondrial intermembrane space. Mol Cell 2006 0.90
87 The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases. Mol Cell Biol 2008 0.89
88 Biogenesis of yeast mitochondrial cytochrome c: a unique relationship to the TOM machinery. J Mol Biol 2003 0.89
89 Cell biology. Connecting organelles. Science 2009 0.87
90 Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol 2011 0.87
91 Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex. Mol Biol Cell 2011 0.86
92 Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase. EMBO Rep 2008 0.84
93 Role of membrane contact sites in protein import into mitochondria. Protein Sci 2015 0.84
94 Assembly of the mitochondrial protein import channel: role of Tom5 in two-stage interaction of Tom40 with the SAM complex. Mol Biol Cell 2010 0.84
95 Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import. Mol Biol Cell 2012 0.83
96 Evolution of mitochondrial protein biogenesis. Biochim Biophys Acta 2009 0.83
97 The mitochondrial machinery for import of precursor proteins. Methods Mol Biol 2007 0.82
98 Mitochondrial inner membrane protease promotes assembly of presequence translocase by removing a carboxy-terminal targeting sequence. Nat Commun 2013 0.81
99 The protein import and assembly machinery of the mitochondrial outer membrane. Biochim Biophys Acta 2004 0.81
100 Mitochondrial F1Fo-ATP synthase: the small subunits e and g associate with monomeric complexes to trigger dimerization. J Mol Biol 2009 0.81
101 Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins. J Mol Biol 2007 0.80
102 Role of phosphatidylethanolamine in the biogenesis of mitochondrial outer membrane proteins. J Biol Chem 2013 0.80
103 Glucose-induced regulation of protein import receptor Tom22 by cytosolic and mitochondria-bound kinases. Cell Metab 2013 0.79
104 SnapShot: import and sorting of mitochondrial proteins. Cell 2009 0.79
105 Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation. Mol Cell 2013 0.76
106 Native techniques for analysis of mitochondrial protein import. Methods Mol Biol 2010 0.76
107 Voltage-coupled conformational dynamics of mitochondrial protein-import channel. Nat Struct Mol Biol 2013 0.75
108 Dynamic organization of the mitochondrial protein import machinery. Biol Chem 2016 0.75