Published in CMAJ on August 14, 2007
Data-driven Quality Improvement in Primary Care - Trial (DQIP) | NCT01425502
Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. N Engl J Med (2012) 5.69
The Norwegian General Practice (NORGEP) criteria for assessing potentially inappropriate prescriptions to elderly patients. A modified Delphi study. Scand J Prim Health Care (2009) 1.56
Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. Biochem Pharmacol (2009) 1.49
Adverse interaction of warfarin and paracetamol: evidence from a post-mortem study. Eur J Clin Pharmacol (2009) 1.44
Drug interactions in general dental practice--considerations for the dental practitioner. Br Dent J (2014) 1.40
Withdrawal of antithrombotic agents and its impact on ischemic stroke occurrence. Stroke (2011) 1.17
Concurrent use of warfarin and antibiotics and the risk of bleeding in older adults. Am J Med (2012) 1.16
Different mechanisms in formation and prevention of indomethacin-induced gastric ulcers. Inflammation (2010) 1.13
Randomized clinical trial of a customized electronic alert requiring an affirmative response compared to a control group receiving a commercial passive CPOE alert: NSAID--warfarin co-prescribing as a test case. J Am Med Inform Assoc (2010) 1.12
Drug interactions with warfarin: what clinicians need to know. CMAJ (2007) 1.05
Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look. Br J Clin Pharmacol (2008) 1.02
Pain management: Part 1: Managing acute and postoperative dental pain. Anesth Prog (2010) 0.89
Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting. Scand J Gastroenterol (2013) 0.88
Drug interactions with phenprocoumon and the risk of serious haemorrhage: a nested case-control study in a large population-based German database. Eur J Clin Pharmacol (2011) 0.87
Long-term anticoagulation in Kawasaki disease: Initial use of low molecular weight heparin is a viable option for patients with severe coronary artery abnormalities. Pediatr Cardiol (2010) 0.87
Co-development of pyogenic granuloma and capillary hemangioma on the alveolar ridge associated with a dental implant: a case report. J Med Case Rep (2014) 0.85
Protocol for the Effective Feedback to Improve Primary Care Prescribing Safety (EFIPPS) study: a cluster randomised controlled trial using ePrescribing data. BMJ Open (2012) 0.84
Demographic, medical, and behavioral characteristics associated with over the counter non-steroidal anti-inflammatory drug use in a population-based cohort: results from the Multi-Ethnic Study of Atherosclerosis. Pharmacoepidemiol Drug Saf (2010) 0.84
Mechanical circulatory support for elderly heart failure patients. Heart Fail Rev (2012) 0.83
Adverse drug interactions. Anesth Prog (2011) 0.83
Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy. World J Gastroenterol (2013) 0.83
Recombinant protein production of earthworm lumbrokinase for potential antithrombotic application. Evid Based Complement Alternat Med (2013) 0.81
Newer antithrombotic drugs. Indian J Crit Care Med (2010) 0.81
The positivity assumption and marginal structural models: the example of warfarin use and risk of bleeding. Eur J Epidemiol (2011) 0.79
The evolving role of nonsteroidal anti-inflammatory drugs in colon cancer prevention: a cause for optimism. J Pharmacol Exp Ther (2015) 0.78
Clinical significance of Helicobacter pylori infection in patients with acute coronary syndromes: an overview of current evidence. Clin Res Cardiol (2014) 0.78
Plenty of pills: polypharmacy prevails in patients of a Danish anticoagulant clinic. Eur J Clin Pharmacol (2011) 0.78
High-risk prescribing and monitoring in primary care: how common is it, and how can it be improved? Ther Adv Drug Saf (2012) 0.77
Physician's fear of anticoagulant therapy in nonvalvular atrial fibrillation. Am J Med Sci (2014) 0.77
Cardiovascular drugs: implications for dental practice. Part 2--antihyperlipidemics and antithrombotics. Anesth Prog (2008) 0.77
Novel single nucleotide polymorphism markers for low dose aspirin-associated small bowel bleeding. PLoS One (2013) 0.77
Characteristics of hemorrhagic peptic ulcers in patients receiving antithrombotic/nonsteroidal antiinflammatory drug therapy. Gut Liver (2012) 0.77
[Analgesics in geriatric patients. Adverse side effects and interactions]. Z Gerontol Geriatr (2015) 0.76
Adherence to guidelines for avoiding drug interactions associated with warfarin--a Nationwide Swedish Register Study. PLoS One (2014) 0.76
Combined antithrombotic therapy. CMAJ (2008) 0.75
Antithrombotic drugs: pharmacology and implications for dental practice. Anesth Prog (2013) 0.75
Prescribing warfarin appropriately to meet patient safety goals. Am Health Drug Benefits (2008) 0.75
Adverse drug reactions in dental practice. Anesth Prog (2014) 0.75
Identification and weighting of the most critical "real-life" drug-drug interactions with acenocoumarol in a tertiary care hospital. Eur J Clin Pharmacol (2012) 0.75
[Polypharmacy and pain treatment]. Wien Med Wochenschr (2010) 0.75
Concern Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med (2000) 29.03
The UK General Practice Research Database. Lancet (1997) 10.62
Validity of the general practice research database. Pharmacotherapy (2003) 6.78
Clinical information for research; the use of general practice databases. J Public Health Med (1999) 3.53
Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: a meta-analysis of randomized trials. Arch Intern Med (2007) 2.50
Extra-cranial bleeding and other symptoms due to low dose aspirin and low intensity oral anticoagulation. Thromb Haemost (1992) 2.24
Warfarin plus aspirin after myocardial infarction or the acute coronary syndrome: meta-analysis with estimates of risk and benefit. Ann Intern Med (2005) 2.22
Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction. Arch Intern Med (2005) 1.91
Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case-control study. BMJ (2006) 1.91
Time variations in the risk of myocardial infarction among elderly users of COX-2 inhibitors. CMAJ (2006) 1.82
Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: A population-based, nested case-control analysis. Am J Epidemiol (2006) 1.59
Diagnosis and treatment of deep-vein thrombosis. CMAJ (2006) 1.44
Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin. Thromb Haemost (2005) 1.23
The incidence of bleeding complications associated with warfarin treatment in general practice in the United Kingdom. Br J Gen Pract (2003) 1.08
Cerebral haemorrhage induced by warfarin - the influence of drug-drug interactions. Pharmacoepidemiol Drug Saf (2007) 0.98
Monitoring anticoagulation in atrial fibrillation. J Thromb Thrombolysis (2006) 0.96
Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA (2005) 6.87
Renal and retinal effects of enalapril and losartan in type 1 diabetes. N Engl J Med (2009) 6.75
Dopamine agonists and the risk of cardiac-valve regurgitation. N Engl J Med (2007) 6.23
Use of statins and the risk of death in patients with prostate cancer. J Clin Oncol (2013) 5.28
Oral fluoroquinolones and the risk of retinal detachment. JAMA (2012) 4.43
Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia. Am J Respir Crit Care Med (2007) 3.94
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study. BMJ (2012) 3.82
The risk for myocardial infarction with cyclooxygenase-2 inhibitors: a population study of elderly adults. Ann Intern Med (2005) 3.82
A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents. Lancet (2004) 3.52
Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus. Am J Psychiatry (2009) 3.33
Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy. CMAJ (2006) 3.18
Androgen deprivation therapy and risk of acute kidney injury in patients with prostate cancer. JAMA (2013) 3.16
Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ (2010) 3.09
The cost-effectiveness of drug-eluting stents: a systematic review. CMAJ (2006) 3.00
A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis. Arthritis Res Ther (2008) 2.87
Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood. Neurology (2008) 2.87
Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study. Chest (2012) 2.65
ACE-I and ARBs in early diabetic nephropathy. J Renin Angiotensin Aldosterone Syst (2002) 2.64
The risk of hospitalized infection in patients with rheumatoid arthritis. J Rheumatol (2008) 2.60
Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study. BMJ (2010) 2.40
Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction. Circulation (2006) 2.34
Antirheumatic drugs and the risk of tuberculosis. Clin Infect Dis (2006) 2.29
The intention-to-treat approach in randomized controlled trials: are authors saying what they do and doing what they say? Clin Trials (2007) 2.19
Fluoroquinolones and the risk of serious arrhythmia: a population-based study. Clin Infect Dis (2012) 2.17
The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom. Arthritis Rheum (2007) 2.16
Use of oral bisphosphonates and the risk of aseptic osteonecrosis: a nested case-control study. J Rheumatol (2008) 2.08
Cardiovascular morbidity and mortality in COPD. Chest (2005) 2.01
Benzodiazepines and elderly drivers: a comparison of pharmacoepidemiological study designs. Pharmacoepidemiol Drug Saf (2007) 1.98
Hepatitis B vaccination and the risk of childhood-onset multiple sclerosis. Arch Pediatr Adolesc Med (2007) 1.96
Traditional risk factors and a Genetic Risk Score are associated with age of first acute coronary syndrome. Heart (2014) 1.95
Discontinuation of statin therapy following an acute myocardial infarction: a population-based study. Eur Heart J (2008) 1.94
Patterns of antibiotic use and risk of hospital admission because of Clostridium difficile infection. CMAJ (2008) 1.91
Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease. J Am Coll Cardiol (2006) 1.91
Natural history of multiple sclerosis with childhood onset. N Engl J Med (2007) 1.89
The nested case-control study in cardiology. Am Heart J (2003) 1.84
Time variations in the risk of myocardial infarction among elderly users of COX-2 inhibitors. CMAJ (2006) 1.82
Gender differences in survival following hospitalisation for COPD. Thorax (2010) 1.73
Isotretinoin and risk for inflammatory bowel disease: a nested case-control study and meta-analysis of published and unpublished data. JAMA Dermatol (2013) 1.70
The early natural history of nephropathy in Type 1 Diabetes: III. Predictors of 5-year urinary albumin excretion rate patterns in initially normoalbuminuric patients. Diabetes (2005) 1.67
The use of inhaled corticosteroids and the risk of adrenal insufficiency. Eur Respir J (2012) 1.67
Clinical utility of C-reactive protein measured at admission, hospital discharge, and 1 month later to predict outcome in patients with acute coronary disease. The RISCA (recurrence and inflammation in the acute coronary syndromes) study. J Am Coll Cardiol (2008) 1.64
Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: A population-based, nested case-control analysis. Am J Epidemiol (2006) 1.59
Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. CMAJ (2012) 1.55
The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation. Thromb Haemost (2013) 1.53
Treating the right patient at the right time: access to specialist consultation and non-invasive testing. Can J Cardiol (2006) 1.52
Oral contraceptives and the risk of gallbladder disease: a comparative safety study. CMAJ (2011) 1.52
Usefulness of soluble fas levels for improving diagnostic accuracy and prognosis for acute coronary syndromes. Am J Cardiol (2010) 1.51
Acute disseminated encephalomyelitis cohort study: prognostic factors for relapse. Eur J Paediatr Neurol (2006) 1.49
First episode of acute CNS inflammatory demyelination in childhood: prognostic factors for multiple sclerosis and disability. J Pediatr (2004) 1.48
Coronary revascularization in diabetic patients: a systematic review and Bayesian network meta-analysis. Ann Intern Med (2014) 1.46
Statin use and risk of epilepsy: a nested case-control study. Neurology (2010) 1.45
The utility of the Health Plan Employer Data and Information Set (HEDIS) asthma measure to predict asthma-related outcomes. Ann Allergy Asthma Immunol (2004) 1.44
Use of lithium and the risk of injurious motor vehicle crash in elderly adults: case-control study nested within a cohort. BMJ (2004) 1.44
End-user involvement in health technology assessment (HTA) development: a way to increase impact. Int J Technol Assess Health Care (2005) 1.44
Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: a nested case-control analysis. Ann Rheum Dis (2012) 1.43
Contemporary cost analysis of single instillation of mitomycin after transurethral resection of bladder tumor in a universal health care system. Urology (2010) 1.42
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes. Diabetes Care (2012) 1.42
Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort. Chest (2012) 1.42
The relationship of diabetic retinopathy to preclinical diabetic glomerulopathy lesions in type 1 diabetic patients: the Renin-Angiotensin System Study. Diabetes (2005) 1.40
Metformin and the incidence of prostate cancer in patients with type 2 diabetes. Cancer Epidemiol Biomarkers Prev (2010) 1.39
Antibiotics in primary prevention of stroke in the elderly. Stroke (2003) 1.39
Willingness to pay to eliminate the risk of restenosis following percutaneous coronary intervention: a contingent valuation. Circ Cardiovasc Qual Outcomes (2010) 1.39
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study. Stroke (2006) 1.38
Androgen-deprivation therapy and the risk of stroke in patients with prostate cancer. Eur Urol (2011) 1.37
Point: were industry-sponsored roflumilast trials appropriate? Yes. Chest (2014) 1.36
Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study. BMJ (2010) 1.32
Probiotic therapy for the prevention and treatment of Clostridium difficile-associated diarrhea: a systematic review. CMAJ (2005) 1.31
MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood. Brain (2004) 1.31
Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: cohort study. BMJ (2014) 1.27
The impact of hepatitis C virus coinfection on HIV progression before and after highly active antiretroviral therapy. J Acquir Immune Defic Syndr (2003) 1.24
Impact of care at a multidisciplinary congestive heart failure clinic: a randomized trial. CMAJ (2005) 1.23
Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster disease. Br J Clin Pharmacol (2008) 1.23
Incidence of and mortality from venous thromboembolism in a real-world population: the Q-VTE Study Cohort. Am J Med (2013) 1.22
The case-crossover study design in pharmacoepidemiology. Stat Methods Med Res (2008) 1.21
Association Between Incretin-Based Drugs and the Risk of Acute Pancreatitis. JAMA Intern Med (2016) 1.21
Trends in the prescription of anti-diabetic medications in the United Kingdom: a population-based analysis. Pharmacoepidemiol Drug Saf (2009) 1.19
Mortality after infection with methicillin-resistant Staphylococcus aureus (MRSA) diagnosed in the community. BMC Med (2008) 1.18
Lifestyle variables and the risk of myocardial infarction in the general practice research database. BMC Cardiovasc Disord (2007) 1.12
Risks of pneumonia in patients with asthma taking inhaled corticosteroids. Am J Respir Crit Care Med (2010) 1.12
Rheumatoid arthritis, its treatments, and the risk of tuberculosis in Quebec, Canada. Arthritis Rheum (2009) 1.10
Gout, allopurinol use, and heart failure outcomes. Arch Intern Med (2010) 1.10
Hematologic malignant neoplasms after drug exposure in rheumatoid arthritis. Arch Intern Med (2008) 1.09
Secular trends of antibacterial prescribing in UK paediatric primary care. J Antimicrob Chemother (2010) 1.08
Fluctuating inflammatory markers in patients with stable ischemic heart disease. Arch Intern Med (2005) 1.07
Associations between ambient air pollution and daily mortality among elderly persons in Montreal, Quebec. Sci Total Environ (2013) 1.06
Body mass index (BMI) and waist circumference (WC) as screening tools for cardiovascular risk factors in Guadeloupean women. J Clin Epidemiol (2002) 1.06
Antimicrobial drugs and community-acquired Clostridium difficile-associated disease, UK. Emerg Infect Dis (2007) 1.06
Rehabilitating digoxin. Eur Heart J (2005) 1.05
Impact of prolonged cyclooxygenase-2 inhibition on inflammatory markers and endothelial function in patients with ischemic heart disease and raised C-reactive protein: a randomized placebo-controlled study. Circulation (2004) 1.05
The association between systemic glucocorticoid therapy and the risk of infection in patients with rheumatoid arthritis: systematic review and meta-analyses. Arthritis Res Ther (2011) 1.04