Published in Mol Cell Biol on August 20, 2007
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The human T-lymphotropic virus type 1 tax protein inhibits nonsense-mediated mRNA decay by interacting with INT6/EIF3E and UPF1. J Virol (2012) 0.99
The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x. J Biol Chem (2010) 0.95
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The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. Cancer Res (2016) 0.87
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Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivo. BMC Cancer (2010) 0.81
The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways. Nucleic Acids Res (2013) 0.81
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A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation. J Biol Chem (2002) 1.43
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Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I. Cancer Res (2003) 1.12
Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. PLoS Biol (2007) 1.04
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Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis. Oncogene (2000) 1.03
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Alternative splicing of the human proto-oncogene c-H-ras renders a new Ras family protein that trafficks to cytoplasm and nucleus. Cancer Res (2003) 0.95
p19ras interacts with and activates p73 by involving the MDM2 protein. J Biol Chem (2006) 0.94
Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells. Mol Cancer Res (2004) 0.92
Nonsense-mediated mRNA decay among human caspases: the caspase-2S putative protein is encoded by an extremely short-lived mRNA. Cell Death Differ (2005) 0.89
Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists. Cancer Res (2006) 0.86
p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin. Oncogene (2001) 0.85
Cell-cycle-dependent three-dimensional redistribution of nuclear proteins, P 120, pKi-67, and SC 35 splicing factor, in the presence of the topoisomerase I inhibitor camptothecin. Exp Cell Res (2003) 0.80
Cytoplasmic nonsense-mediated mRNA decay for a nonsense (W262X) transcript of the gene responsible for hereditary tyrosinemia, fumarylacetoacetate hydrolase. Biochem Biophys Res Commun (2004) 0.80
p19ras brings a new twist to the regulation of p73 by Mdm2. Sci STKE (2006) 0.79
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. Nat Struct Mol Biol (2010) 2.19
Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth. Cancer Res (2009) 1.98
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy. Nat Med (2011) 1.87
Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy. Nat Struct Mol Biol (2011) 1.73
Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness. Nat Struct Mol Biol (2012) 1.67
Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell (2005) 1.66
The YTH domain is a novel RNA binding domain. J Biol Chem (2010) 1.45
Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer. Proc Natl Acad Sci U S A (2008) 1.43
Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol (2002) 1.42
Cotranscriptional exon skipping in the genotoxic stress response. Nat Struct Mol Biol (2010) 1.39
Splicing factor and exon profiling across human tissues. Nucleic Acids Res (2010) 1.37
Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation. J Cell Biol (2011) 1.25
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22
HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects. Hum Mol Genet (2010) 1.21
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants. BMC Bioinformatics (2007) 1.21
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Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis. Cancer Res (2010) 1.12
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A distinct mechanism for coactivator versus corepressor function by histone methyltransferase G9a in transcriptional regulation. J Biol Chem (2011) 1.09
Coregulators: transducing signal from transcription to alternative splicing. Trends Endocrinol Metab (2007) 1.09
Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer. Cancer Res (2010) 1.08
Gene-specific patterns of coregulator requirements by estrogen receptor-α in breast cancer cells. Mol Endocrinol (2012) 1.07
ASEtrap: a biological method for speeding up the exploration of spliceomes. Genome Res (2006) 1.07
Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function. PLoS One (2011) 1.07
Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin. Genome Res (2013) 1.06
Splicing programs and cancer. J Nucleic Acids (2011) 1.06
The emerging role of pre-messenger RNA splicing in stress responses: sending alternative messages and silent messengers. RNA Biol (2011) 1.04
Follicle-stimulating hormone increases testicular Anti-Mullerian hormone (AMH) production through sertoli cell proliferation and a nonclassical cyclic adenosine 5'-monophosphate-mediated activation of the AMH Gene. Mol Endocrinol (2003) 0.97
Mechanistic differences in the activation of estrogen receptor-alpha (ER alpha)- and ER beta-dependent gene expression by cAMP signaling pathway(s). J Biol Chem (2003) 0.97
Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F. PLoS One (2012) 0.95
Coupled alteration of transcription and splicing by a single oncogene: boosting the effect on cyclin D1 activity. Cell Cycle (2008) 0.93
Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes. Mol Cell Biol (2008) 0.92
BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells. Blood (2013) 0.92
The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling. EMBO Mol Med (2013) 0.91
Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers. PLoS One (2008) 0.90
Alternative splicing and breast cancer. RNA Biol (2010) 0.89
Sudemycin E influences alternative splicing and changes chromatin modifications. Nucleic Acids Res (2014) 0.88
In vivo NMDA receptor activation accelerates motor unit maturation, protects spinal motor neurons, and enhances SMN2 gene expression in severe spinal muscular atrophy mice. J Neurosci (2010) 0.88
Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion. J Cell Sci (2012) 0.87
Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis. J Hepatol (2013) 0.86
Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis. Cell Reprogram (2013) 0.86
The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export. Nucleic Acids Res (2012) 0.86
SKF-82958 is a subtype-selective estrogen receptor-alpha (ERalpha ) agonist that induces functional interactions between ERalpha and AP-1. J Biol Chem (2001) 0.85
Analysis of co-transcriptional RNA processing by RNA-ChIP assay. Methods Mol Biol (2012) 0.85
A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas. Carcinogenesis (2012) 0.84
hCAF1/CNOT7 regulates interferon signalling by targeting STAT1. EMBO J (2013) 0.83
CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia. Oncotarget (2013) 0.82
The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways. Nucleic Acids Res (2013) 0.81
Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro. Biochim Biophys Acta (2013) 0.81
Molecular characterization of a patient presumed to have prader-willi syndrome. Clin Med Insights Case Rep (2013) 0.80
Hypothalamic-pituitary dysfunction following traumatic brain injury affects functional improvement during acute inpatient rehabilitation. J Head Trauma Rehabil (2013) 0.80
Autoimmune mediated regulation of ovarian tumor growth. Gynecol Oncol (2011) 0.78
Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene. Br J Haematol (2011) 0.75