Published in Chem Biodivers on August 01, 2007
Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. J Am Chem Soc (2009) 1.18
Biosynthesis, degradation and pharmacological importance of the fatty acid amides. Drug Discov Today (2008) 1.00
Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates. J Med Chem (2008) 0.97
Structure-property relationships of a class of carbamate-based fatty acid amide hydrolase (FAAH) inhibitors: chemical and biological stability. ChemMedChem (2009) 0.93
Mutations in Arabidopsis fatty acid amide hydrolase reveal that catalytic activity influences growth but not sensitivity to abscisic acid or pathogens. J Biol Chem (2009) 0.90
Differential effects of single versus repeated alcohol withdrawal on the expression of endocannabinoid system-related genes in the rat amygdala. Alcohol Clin Exp Res (2011) 0.88
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet (2013) 0.84
Neurochemical and neuropharmacological aspects of circadian disruptions: an introduction to asynchronization. Curr Neuropharmacol (2011) 0.84
Application of a SCC-DFTB QM/MM approach to the investigation of the catalytic mechanism of fatty acid amide hydrolase. J Mol Model (2011) 0.79
Biochemical and mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase inhibition. PLoS One (2012) 0.79
Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors. J Med Chem (2013) 0.77
The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119. Br J Pharmacol (2012) 0.76
Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs. Eur J Med Chem (2003) 1.60
Gauging a hydrocarbon ruler by an intrinsic exciton probe. Biochemistry (2007) 1.14
Spectral and crystallographic study of pyridinic analogues of nimesulide: determination of the active form of methanesulfonamides as COX-2 selective inhibitors. J Med Chem (2002) 0.87
First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: discovery of an extra-pocket in the catalytic domain responsible for its endo-activity. Biochimie (2012) 0.86
Advantages of cocrystallization in the field of solid-state pharmaceutical chemistry: L-Proline and MnCl(2). Eur J Med Chem (2010) 0.85
Combined effect of stacking and solvation on the spontaneous mutation in DNA. Phys Chem Chem Phys (2011) 0.81
beta-Lactams derived from a carbapenem chiron are selective inhibitors of human fatty acid amide hydrolase versus human monoacylglycerol lipase. J Med Chem (2009) 0.79
Stochastic simulation of structural properties of natively unfolded and denatured proteins. J Mol Model (2012) 0.79
Synthesis, molecular modelling and enzymatic evaluation of (+/-)3,5-diphenyl-2-thioxoimidazolidin-4-ones as new potential cyclooxygenase inhibitors. Bioorg Med Chem (2005) 0.78
Towards a universal method for protein refolding: the trimeric beta barrel membrane Omp2a as a test case. Biotechnol Bioeng (2012) 0.78
Design, synthesis and evaluation of graftable thrombin inhibitors for the preparation of blood-compatible polymer materials. Org Biomol Chem (2005) 0.78
Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor. Bioorg Med Chem Lett (2002) 0.77
An unprecedented reversible mode of action of β-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH). Eur J Med Chem (2012) 0.77
Asparagine 42 of the conserved endo-inulinase INU2 motif WMNDPN from Aspergillus ficuum plays a role in activity specificity. FEBS Open Bio (2013) 0.77
New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers. Bioorg Med Chem (2008) 0.77
Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition. Eur J Med Chem (2011) 0.76
Exploration of the binding mode of indanesulfonamides as selective inhibitors of human carbonic anhydrase type VII by targeting Lys 91. ChemMedChem (2007) 0.75
(S)-1-(Pent-4'-enoyl)-4-(hydroxymethyl)-azetidin-2-one derivatives as inhibitors of human fatty acid amide hydrolase (hFAAH): synthesis, biological evaluation and molecular modelling. J Enzyme Inhib Med Chem (2013) 0.75
Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels. J Med Chem (2011) 0.75
Structural study of piracetam polymorphs and cocrystals: crystallography redetermination and quantum mechanics calculations. Acta Crystallogr B (2011) 0.75
Polypyrrole-supported membrane proteins for bio-inspired ion channels. ACS Appl Mater Interfaces (2015) 0.75
Comparison of microhydration methods: protonated glycine as a working example. J Phys Chem B (2011) 0.75
Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors. J Med Chem (2004) 0.75
Multiscale molecular dynamics simulations of sodium dodecyl sulfate micelles: from coarse-grained to all-atom resolution. J Mol Model (2014) 0.75
Refolding of SDS-denatured proteins using amphipathic cosolvents and osmolytes. Curr Protoc Protein Sci (2013) 0.75
Specific interactions in complexes formed by DNA and conducting polymer building blocks: guanine and 3,4-(ethylenedioxy)thiophene. J Phys Chem A (2011) 0.75
Cobalt-mediated radical polymerization of acrylonitrile: kinetics investigations and DFT calculations. Chemistry (2008) 0.75