Published in Cell Tissue Res on September 04, 2007
Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition. Dev Cell (2005) 1.79
The cytoplasmic plaque of tight junctions: a scaffolding and signalling center. Biochim Biophys Acta (2007) 1.35
Claudin-1 and claudin-5 expression patterns differentiate lung squamous cell carcinomas from adenocarcinomas. Mod Pathol (2007) 1.30
Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell (2006) 1.22
Molecular complexity of vertebrate tight junctions (Review). Mol Membr Biol (2002) 1.12
Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression. J Cell Sci (2004) 1.07
Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions. Mol Biol Cell (2008) 1.06
Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. Mol Cancer Res (2004) 1.05
A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells. J Biol Chem (2011) 1.03
PLEKHA7 is an adherens junction protein with a tissue distribution and subcellular localization distinct from ZO-1 and E-cadherin. PLoS One (2010) 1.03
Evidence for a functional interaction between cingulin and ZO-1 in cultured cells. J Biol Chem (2002) 0.93
Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol (2008) 0.90
Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury. J Cell Sci (2012) 0.86
Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions. Mol Membr Biol (2010) 0.85
The control of gene expression and cell proliferation by the epithelial apical junctional complex. Essays Biochem (2012) 0.83
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. PLoS One (2013) 0.79
Distinct domains of paracingulin are involved in its targeting to the actin cytoskeleton and regulation of apical junction assembly. J Biol Chem (2012) 0.76