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A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med (2003) 11.17

The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group. Lancet (1997) 9.34

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Clinical and echocardiographic features of hypereosinophilic syndromes. Am J Cardiol (2000) 2.54

Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature (1986) 2.41

Meta-analysis: low-molecular-weight heparin and bleeding in patients with severe renal insufficiency. Ann Intern Med (2006) 2.40

Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders. Blood (2002) 2.34

Comparison of high-dose with low-dose subcutaneous heparin to prevent left ventricular mural thrombosis in patients with acute transmural anterior myocardial infarction. N Engl J Med (1989) 2.28

Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest (2004) 2.19

Department of Veterans Affairs Cooperative Studies Program Clinical Trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results of the CHAMP study. Circulation (2002) 2.16

Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet (1987) 1.98

Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med (1983) 1.96

Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction. Arch Intern Med (2005) 1.91

Prophylactic anticoagulation with enoxaparin: Is the subcutaneous route appropriate in the critically ill? Crit Care Med (2003) 1.87

Neurologic dysfunction in the idiopathic hypereosinophilic syndrome. Ann Intern Med (1985) 1.87

The natural history of left ventricular thrombus in myocardial infarction: a rationale in support of masterly inactivity. J Am Coll Cardiol (1989) 1.85

Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease. Int J Cardiol (2007) 1.75

Clinical, haemodynamic, and angiographic findings in Löffler's eosinophilic endocarditis. Br Heart J (1976) 1.72

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Evaluation of cardiac involvement in hypereosinophilic syndrome: complementary roles of transthoracic, transesophageal, and contrast echocardiography. Echocardiography (2006) 1.66

Eosinophils are a major intravascular location for tissue factor storage and exposure. Blood (2006) 1.45

Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations. J Infect Dis (1986) 1.45

Eosinophil cationic granule proteins impair thrombomodulin function. A potential mechanism for thromboembolism in hypereosinophilic heart disease. J Clin Invest (1993) 1.45

Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Blood (2003) 1.37

Eosinophilic myocarditis. Heart Fail Clin (2005) 1.34

Endomyocardial fibrosis and intracardiac thrombus occurring in idiopathic hypereosinophilic syndrome. AJR Am J Roentgenol (2005) 1.33

Enhancement of factor XII dependent reactions by eosinophil cationic protein. Thromb Res (1979) 1.30

Activation of platelets by eosinophil granule proteins. J Exp Med (1990) 1.29

Acenocoumarol and heparin compared with acenocoumarol alone in the initial treatment of proximal-vein thrombosis. N Engl J Med (1992) 1.27

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states. Blood (2005) 1.18

Cardiac manifestations of Churg-Strauss syndrome: report of a case and review of the literature. Am Heart J (1990) 1.08

Thrombotic microangiopathy associated with the hypereosinophilic syndrome. Kidney Int (2005) 1.08

Identification of risk factors for bleeding during treatment of acute venous thromboembolism with heparin or low molecular weight heparin. Blood (1991) 1.07

Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis. JAMA (1999) 1.05

Cardiac involvement in the Churg-Strauss syndrome. Am J Cardiol (2006) 1.04

Endomyocardiopathy with eosinophilia. Mayo Clin Proc (1976) 1.03

Left ventricular thrombus following acute myocardial infarction: a prospective serial echocardiographic study of 96 patients. Eur Heart J (1983) 1.01

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Magnetic resonance imaging of the heart in a patient with hypereosinophilic syndrome. Am J Med (2006) 1.00

Hypereosinophilia with systemic thrombophlebitis. Hum Pathol (2005) 0.99

Serum concentration of cardiac Troponin T in patients with hypereosinophilic syndrome treated with imatinib is predictive of adverse outcomes. Blood (2003) 0.98

Heart transplantation in a patient with endomyocardial fibrosis due to hypereosinophilic syndrome. Transplantation (2007) 0.97

Noncardiovascular findings associated with heart disease in the idiopathic hypereosinophilic syndrome. Am J Cardiol (1983) 0.96

Idiopathic hypereosinophilic syndrome: magnetic resonance imaging findings in endomyocardial fibrosis. Australas Radiol (2001) 0.96

Sudden death of a patient with primary hypereosinophilia, colon tumours, and pulmonary emboli. J Clin Pathol (2004) 0.93

Frequency of major hemorrhage in patients treated with unfractionated intravenous heparin for deep venous thrombosis or pulmonary embolism: a study in routine clinical practice. Arch Intern Med (2000) 0.93

Veno-occlusive disease in hypereosinophilic syndrome. Intern Med (1995) 0.93

In reply to 'Cardiotoxicity of the cancer therapeutic agent imatinib mesylate'. Nat Med (2007) 0.92

Cerebral sinovenous thrombosis in the idiopathic hypereosinophilic syndrome in childhood. Pediatr Radiol (1999) 0.92

Eosinophilic pericarditis: a rare complication of idiopathic hypereosinophilic syndrome in a child. Pediatr Cardiol (2005) 0.92

Portal vein thrombosis in hypereosinophilic syndrome. Am J Gastroenterol (2002) 0.91

Biventricular assist device placement and immunosuppression as therapy for necrotizing eosinophilic myocarditis. Nat Clin Pract Cardiovasc Med (2005) 0.90

Idiopathic hypereosinophilic syndrome associated with cutaneous infarction and deep venous thrombosis. Br J Dermatol (2003) 0.89

Effect of early anticoagulation on the frequency of left ventricular thrombi after anterior wall acute myocardial infarction. Am J Cardiol (1986) 0.89

Possible mechanisms of fibrin deposition in the hypereosinophilic syndrome. Haemostasis (1989) 0.88

Clinical correlations in patients with acute myocardial infarction and left ventricular thrombus detected by two-dimensional echocardiography. Am J Med (1982) 0.88

A case of idiopathic hypereosinophilic syndrome complicated with disseminated intravascular coagulation. Am J Hematol (1998) 0.88

Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. J Card Surg (2005) 0.88

Hypereosinophilic syndrome with rapid progression of cardiac involvement and early echocardiographic abnormalities. Am Heart J (1995) 0.87

Idiopathic hypereosinophilic syndrome complicated by central sinovenous thrombosis. Brain Dev (2006) 0.87

Aortic and mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg (1988) 0.84

Mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg (1991) 0.84

Hypereosinophilic multiple thrombosis. A proposal of a new designation of disseminated eosinophilic "collagen disease". Angiology (1977) 0.83

Acute aortic thrombosis despite anticoagulant therapy in idiopathic hypereosinophilic syndrome. J R Soc Med (1998) 0.83

Effects of full-dose heparin anticoagulation on the development of left ventricular thrombosis in acute transmural myocardial infarction. J Am Coll Cardiol (1986) 0.83

Hepatic vein obstruction in idiopathic hypereosinophilic syndrome. Arch Intern Med (1985) 0.83

Hypereosinophilic thrombus causing aortic stenosis and myocardial infarction. Ann Thorac Surg (2003) 0.82

Duration of therapy for acute venous thromboembolism. Clin Chest Med (2003) 0.81

A case of hypereosinophilic syndrome associated with factor V Leiden mutation and thrombosis. Br J Haematol (1998) 0.81

Thromboembolism in a patient with transient eosinophilia. Ann Hematol (1996) 0.80

Deep venous thrombosis in hypereosinophilic syndrome. Am Fam Physician (1994) 0.79

Platelet interactions with vessel wall components during thrombogenesis. Blood Cells Mol Dis (2006) 0.79

Cutaneous microthrombi: a histologic clue to the diagnosis of hypereosinophilic syndrome. Am J Dermatopathol (1987) 0.78

Idiopathic hypereosinophilia associated with hepatic vein thrombosis. Arch Intern Med (1987) 0.77

Hypereosinophilic syndrome accompanying gangrene of the toes with peripheral arterial occlusion--a case report. Angiology (2006) 0.77

Cine-MRI-aided endomyocardectomy in idiopathic hypereosinophilic syndrome. Ann Thorac Surg (1996) 0.77

Increased heparin requirement with hypereosinophilic syndrome. Anesthesiology (1981) 0.77

Unusual cardiac manifestation of hypereosinophilic syndrome. Postgrad Med J (2002) 0.77

Mitral valve repair in idiopathic hypereosinophilic syndrome. J Heart Valve Dis (2004) 0.77

Recurrent thrombosis of prosthetic mitral valve in idiopathic hypereosinophilic syndrome. J Heart Valve Dis (2002) 0.76

Multiple valvar replacements for hypereosinophilic syndrome. Cardiol Young (2002) 0.76

Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol (2007) 2.76

Cardiac studies in patients treated with depsipeptide, FK228, in a phase II trial for T-cell lymphoma. Clin Cancer Res (2006) 2.61

Aortic dilatation and dissection in Turner syndrome. Circulation (2007) 1.65

Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with [corrected] human epidermal growth factor receptor 2-positive metastatic breast cancer. Clin Cancer Res (2008) 1.50

Individualized treatment for iron-deficiency anemia in adults. Am J Med (2008) 1.50

Growth hormone treatment and left ventricular dimensions in Turner syndrome. J Pediatr (2007) 1.44

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Clinical and molecular responses in lung cancer patients receiving Romidepsin. Clin Cancer Res (2008) 1.34

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Oxidative stress in asymptomatic subjects with hereditary hemochromatosis. Am J Hematol (2007) 1.08

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Aortic valve disease in Turner syndrome. J Am Coll Cardiol (2008) 1.00

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Prolonged rate-corrected QT interval and other electrocardiogram abnormalities in girls with Turner syndrome. Pediatrics (2006) 0.94

Challenges of evaluating the cardiac effects of anticancer agents. Clin Cancer Res (2006) 0.90

Disseminated intravascular coagulation in an ambulatory young woman. J Lab Clin Med (2005) 0.90

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Spectrum of aortic valve abnormalities associated with aortic dilation across age groups in Turner syndrome. Circ Cardiovasc Imaging (2013) 0.88

Left ventricular systolic function during stress echocardiography exercise in subjects with asymptomatic hereditary hemochromatosis. Am J Cardiol (2006) 0.88

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Association between fetal lymphedema and congenital cardiovascular defects in Turner syndrome. Pediatrics (2005) 0.87

Prolongation of the cardiac QTc interval in Turner syndrome. Medicine (Baltimore) (2006) 0.87

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Exercise capacity of cardiac asymptomatic hereditary hemochromatosis subjects. Med Sci Sports Exerc (2007) 0.84

Venlafaxine-induced ecchymoses and impaired platelet aggregation. Eur J Haematol (2006) 0.83

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Serious aortic complications in a patient with Turner syndrome. Eur J Pediatr (2012) 0.75

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