Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy.

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Published in Breast Cancer Res on January 01, 2007

Authors

Anna L Stratford1, Golareh Habibi, Arezoo Astanehe, Helen Jiang, Kaiji Hu, Eugene Park, Ashleen Shadeo, Timon P H Buys, Wan Lam, Trevor Pugh, Marco Marra, Torsten O Nielsen, Uwe Klinge, Peter R Mertens, Samuel Aparicio, Sandra E Dunn

Author Affiliations

1: Laboratory for Oncogenomic Research, Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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