Published in J Biol Chem on September 19, 2007
Fine-tuning of GPCR activity by receptor-interacting proteins. Nat Rev Mol Cell Biol (2009) 2.39
Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins. Br J Pharmacol (2012) 1.69
Na+/H+ exchanger regulatory factor 1 (NHERF1) directly regulates osteogenesis. J Biol Chem (2012) 1.52
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis. J Biol Chem (2010) 1.25
Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling. J Bone Miner Res (2012) 1.22
Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors. Pharmacol Rev (2011) 1.22
NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding. Mol Pharmacol (2009) 1.20
Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway. Mol Biol Cell (2008) 1.16
Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits. J Biol Chem (2010) 1.02
The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis. J Biol Chem (2008) 1.00
Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation. J Biol Chem (2013) 0.96
Non-canonical signaling of the PTH receptor. Trends Pharmacol Sci (2012) 0.95
Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains. J Biol Chem (2011) 0.94
Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling. Oncogene (2010) 0.93
Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking. Mol Endocrinol (2009) 0.93
Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells. J Biol Chem (2010) 0.93
Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer. J Biol Chem (2010) 0.92
Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. J Biol Chem (2016) 0.92
Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transport. J Biol Chem (2012) 0.91
Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease. PLoS One (2013) 0.90
The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membrane. PLoS One (2010) 0.90
Structural basis for NHERF1 PDZ domain binding. Biochemistry (2012) 0.90
Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth. Mol Biol Cell (2016) 0.89
EBP50 inhibits the anti-mitogenic action of the parathyroid hormone type 1 receptor in vascular smooth muscle cells. J Mol Cell Cardiol (2010) 0.88
Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor. J Biol Chem (2010) 0.87
The parathyroid hormone 1 receptor directly binds to the FERM domain of ezrin, an interaction that supports apical receptor localization and signaling in LLC-PK1 cells. Mol Endocrinol (2009) 0.87
G protein-coupled receptors: what a difference a 'partner' makes. Int J Mol Sci (2014) 0.86
Subcellular sorting of the G-protein coupled mouse somatostatin receptor 5 by a network of PDZ-domain containing proteins. PLoS One (2014) 0.86
Structural insights into neutrophilic migration revealed by the crystal structure of the chemokine receptor CXCR2 in complex with the first PDZ domain of NHERF1. PLoS One (2013) 0.85
Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells. Mol Endocrinol (2009) 0.85
NHERF1 regulation of PTH-dependent bimodal Pi transport in osteoblasts. Bone (2012) 0.84
Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization. J Biol Chem (2012) 0.84
International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors. Pharmacol Rev (2015) 0.83
Regulation of human organic anion transporter 4 by protein kinase C and NHERF-1: altering the endocytosis of the transporter. Pharm Res (2010) 0.83
Moesin controls clathrin-mediated S1PR1 internalization in T cells. PLoS One (2013) 0.81
Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase. J Biomol Tech (2009) 0.81
The rates of protein synthesis and degradation account for the differential response of neurons to spaced and massed training protocols. PLoS Comput Biol (2011) 0.80
A naturally occurring isoform inhibits parathyroid hormone receptor trafficking and signaling. J Bone Miner Res (2011) 0.79
Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins. Pharmacol Rev (2015) 0.78
Two distinct calmodulin binding sites in the third intracellular loop and carboxyl tail of angiotensin II (AT(1A)) receptor. PLoS One (2013) 0.78
Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting. J Bone Miner Res (2011) 0.78
Fluorescent ligand-directed co-localization of the parathyroid hormone 1 receptor with the brush-border scaffold complex of the proximal tubule reveals hormone-dependent changes in ezrin immunoreactivity consistent with inactivation. Biochim Biophys Acta (2012) 0.77
Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells. PLoS One (2012) 0.77
Disruption of β-catenin binding to parathyroid hormone (PTH) receptor inhibits PTH-stimulated ERK1/2 activation. Biochem Biophys Res Commun (2015) 0.77
Sustained signalling by PTH modulates IP3 accumulation and IP3 receptors through cyclic AMP junctions. J Cell Sci (2014) 0.76
Oxidation inhibits PTH receptor signaling and trafficking. Biochem Biophys Res Commun (2016) 0.75
Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. Biochemistry (2017) 0.75
Establishment of HIV-1 model cell line GHOST(3) with stable DRiP78 and NHERF1 knockdown. Dongwuxue Yanjiu (2015) 0.75
Heterotrimeric G proteins in the control of parathyroid hormone actions. J Mol Endocrinol (2017) 0.75
Induction of leptin resistance through direct interaction of C-reactive protein with leptin. Nat Med (2006) 4.35
The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol (2006) 2.18
A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: the PrOP study. J Bone Miner Res (2013) 1.65
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50). J Biol Chem (2003) 1.60
An HSV vector system for selection of ligand-gated ion channel modulators. Nat Methods (2007) 1.57
Na+/H+ exchanger regulatory factor 1 (NHERF1) directly regulates osteogenesis. J Biol Chem (2012) 1.52
NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors. J Biol Chem (2007) 1.48
Continuous PTH and PTHrP infusion causes suppression of bone formation and discordant effects on 1,25(OH)2 vitamin D. J Bone Miner Res (2005) 1.34
D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. Am J Physiol Regul Integr Comp Physiol (2006) 1.32
Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. Cell Mol Life Sci (2010) 1.30
Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis. Diabetes (2007) 1.29
Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity. Adv Pharmacol (2011) 1.27
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis. J Biol Chem (2010) 1.25
Caveolin-1 regulates cellular trafficking and function of the glucagon-like Peptide 1 receptor. Mol Endocrinol (2006) 1.23
Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors. Pharmacol Rev (2011) 1.22
NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding. Mol Pharmacol (2009) 1.20
Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway. Mol Biol Cell (2008) 1.16
Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport. Am J Physiol Renal Physiol (2003) 1.15
Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR. Pflugers Arch (2008) 1.12
Parathyroid hormone receptor trafficking contributes to the activation of extracellular signal-regulated kinases but is not required for regulation of cAMP signaling. J Biol Chem (2004) 1.10
Regulation of parathyroid hormone type 1 receptor dynamics, traffic, and signaling by the Na+/H+ exchanger regulatory factor-1 in rat osteosarcoma ROS 17/2.8 cells. Mol Endocrinol (2008) 1.06
Calcium-sensing receptor regulation of PTH-dependent calcium absorption by mouse cortical ascending limbs. Am J Physiol Renal Physiol (2002) 1.06
Angiotensin II type 1 receptor antagonists inhibit cell proliferation and angiogenesis in breast cancer. Cancer Lett (2012) 1.06
Parathyroid hormone-related protein for the treatment of postmenopausal osteoporosis: defining the maximal tolerable dose. J Clin Endocrinol Metab (2010) 1.03
Frequent low expression of chromatin remodeling gene ARID1A in breast cancer and its clinical significance. Cancer Epidemiol (2011) 1.03
Calcium and bone disease. Biofactors (2011) 1.02
Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits. J Biol Chem (2010) 1.02
Effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter pylori eradication: a meta-analysis. Helicobacter (2008) 1.00
Safety and tolerability of subcutaneous PTHrP(1-36) in healthy human volunteers: a dose escalation study. Osteoporos Int (2005) 1.00
Development of potent glucagon-like peptide-1 agonists with high enzyme stability via introduction of multiple lactam bridges. J Med Chem (2010) 0.99
Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization. Endocrinology (2007) 0.98
Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: definition of an arterial smooth muscle PTHrP/p27kip1 pathway. Circ Res (2006) 0.98
Insights into the evolution of gene organization and multidrug resistance from Klebsiella pneumoniae plasmid pKF3-140. Gene (2013) 0.97
A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. J Am Chem Soc (2014) 0.96
Ligand-selective dissociation of activation and internalization of the parathyroid hormone (PTH) receptor: conditional efficacy of PTH peptide fragments. Endocrinology (2004) 0.95
Calcium-sensing receptor regulation of renal mineral ion transport. Cell Calcium (2004) 0.95
COX-2 expression is correlated with VEGF-C, lymphangiogenesis and lymph node metastasis in human cervical cancer. Microvasc Res (2011) 0.95
Differential effects of intermittent PTH(1-34) and PTH(7-34) on bone microarchitecture and aortic calcification in experimental renal failure. Bone (2008) 0.94
Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains. J Biol Chem (2011) 0.94
A 7-day continuous infusion of PTH or PTHrP suppresses bone formation and uncouples bone turnover. J Bone Miner Res (2011) 0.94
Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway. J Cell Physiol (2010) 0.93
Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking. Mol Endocrinol (2009) 0.93
Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transport. J Biol Chem (2012) 0.91
Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells. Am J Physiol Renal Physiol (2006) 0.91
Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers. PLoS One (2013) 0.90
Structural basis for NHERF1 PDZ domain binding. Biochemistry (2012) 0.90
Parathyroid hormone-related protein: an essential physiological regulator of adult bone mass. Endocrinology (2004) 0.90
Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger expression in distal convoluted tubule cells. Am J Physiol Renal Physiol (2002) 0.90
Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy. Cardiovasc Res (2012) 0.90
Implication of USP22 in the regulation of BMI-1, c-Myc, p16INK4a, p14ARF, and cyclin D2 expression in primary colorectal carcinomas. Diagn Mol Pathol (2010) 0.88
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model. Carcinogenesis (2013) 0.88
EBP50 inhibits the anti-mitogenic action of the parathyroid hormone type 1 receptor in vascular smooth muscle cells. J Mol Cell Cardiol (2010) 0.88
Identification of differentially expressed proteins of Arthrospira (Spirulina) plantensis-YZ under salt-stress conditions by proteomics and qRT-PCR analysis. Proteome Sci (2013) 0.87
COX-2-mediated regulation of VEGF-C in association with lymphangiogenesis and lymph node metastasis in lung cancer. Anat Rec (Hoboken) (2010) 0.87
Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor. J Biol Chem (2010) 0.87
Fangchinoline induces G1 arrest in breast cancer cells through cell-cycle regulation. Phytother Res (2013) 0.87
AT2 receptors cross talk with AT1 receptors through a nitric oxide- and RhoA-dependent mechanism resulting in decreased phospholipase D activity. Am J Physiol Renal Physiol (2004) 0.86
Bioinformatic analysis of the Acinetobacter baumannii phage AB1 genome. Gene (2012) 0.86
PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes. Nitric Oxide (2013) 0.86
Arsenic trioxide induces G2/M arrest in hepatocellular carcinoma cells by increasing the tumor suppressor PTEN expression. J Cell Biochem (2012) 0.86
Effects of curcumin on levels of nitric oxide synthase and AQP-4 in a rat model of hypoxia-ischemic brain damage. Brain Res (2012) 0.85
Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells. Mol Endocrinol (2009) 0.85
Angiotensin II suppresses adriamycin-induced apoptosis through activation of phosphatidylinositol 3-kinase/Akt signaling in human breast cancer cells. Acta Biochim Biophys Sin (Shanghai) (2008) 0.85
Knockdown of osteopontin chemosensitizes MDA-MB-231 cells to cyclophosphamide by enhancing apoptosis through activating p38 MAPK pathway. Cancer Biother Radiopharm (2011) 0.85
Mechanical nanosprings: induced coiling and uncoiling of ultrathin Au nanowires. J Am Chem Soc (2010) 0.84
High capacity Na+/H+ exchange activity in mineralizing osteoblasts. J Cell Physiol (2011) 0.84
The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1). Arterioscler Thromb Vasc Biol (2011) 0.84
NHERF1 regulation of PTH-dependent bimodal Pi transport in osteoblasts. Bone (2012) 0.84
Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria. Chem Commun (Camb) (2010) 0.83
EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration. J Mol Cell Cardiol (2012) 0.83
Genetic data of 15 STR loci in Chinese Yunnan Han population. Forensic Sci Int Genet (2008) 0.83
Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer. Cell Biochem Biophys (2012) 0.82
ABCC3 as a marker for multidrug resistance in non-small cell lung cancer. Sci Rep (2013) 0.82
Ultrafast and directional diffusion of lithium in phosphorene for high-performance lithium-ion battery. Nano Lett (2015) 0.82
Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese. Med Oncol (2011) 0.82
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C. Anat Rec (Hoboken) (2009) 0.81
Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase. J Biomol Tech (2009) 0.81
Fluoride promotes viability and differentiation of osteoblast-like Saos-2 cells via BMP/Smads signaling pathway. Biol Trace Elem Res (2013) 0.81
Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-κB (NF-κB): a feed-forward loop for systemic and vascular inflammation. J Biol Chem (2013) 0.80
Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells. Hypertension (2003) 0.80
Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking. Mol Endocrinol (2013) 0.80
AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells. J Pharmacol Exp Ther (2004) 0.79
A naturally occurring isoform inhibits parathyroid hormone receptor trafficking and signaling. J Bone Miner Res (2011) 0.79
[Inhibitory effects of genistein on the synthesis of DNA and the protein expression of cyclin D1 in human gastric carcinoma cell-line]. Wei Sheng Yan Jiu (2002) 0.78
Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting. J Bone Miner Res (2011) 0.78
Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells. J Cardiovasc Pharmacol (2005) 0.78