Published in J Neuropathol Exp Neurol on October 01, 2007
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge. Nat Rev Cancer (2014) 2.10
De novo induction of genetically engineered brain tumors in mice using plasmid DNA. Cancer Res (2009) 1.49
The cellular origin for malignant glioma and prospects for clinical advancements. Expert Rev Mol Diagn (2012) 1.02
Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens. Mol Biol Cell (2012) 0.97
From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity. Oncotarget (2015) 0.96
Studying a complex tumor: potential and pitfalls. Cancer J (2012) 0.87
Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors. J Oncol (2010) 0.86
MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation. J Neurooncol (2010) 0.83
A multi-resolution textural approach to diagnostic neuropathology reporting. J Neurooncol (2015) 0.80
Frequent heterogeneous missense mutations of GGAP2 in prostate cancer: implications for tumor biology, clonality and mutation analysis. PLoS One (2012) 0.78
Mutations of the human interferon alpha-2b gene in brain tumor patients exposed to different environmental conditions. Cancer Gene Ther (2015) 0.75
Clinical neuropathology practice guide 1-2013: molecular subtyping of glioblastoma: ready for clinical use? Clin Neuropathol (2013) 0.75
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron (2011) 18.73
The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment. J Clin Oncol (2005) 3.48
p53 suppresses the self-renewal of adult neural stem cells. Development (2006) 3.35
Muscle injuries: biology and treatment. Am J Sports Med (2005) 3.15
Four-fold increase in direct costs of stroke survivors with spasticity compared with stroke survivors without spasticity: the first year after the event. Stroke (2009) 3.10
The UMD-p53 database: new mutations and analysis tools. Hum Mutat (2003) 2.89
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission. EMBO J (2011) 2.71
The significance of latissimus dorsi flap innervation in delayed breast reconstruction: a prospective randomized study-magnetic resonance imaging and histologic findings. Plast Reconstr Surg (2011) 2.61
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain (2010) 2.49
Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells. Circ Res (2008) 2.15
Retracted VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification. Cell (2009) 2.11
The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone. Nat Genet (2005) 2.05
Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle (2008) 2.03
Mechanical loading regulates the expression of tenascin-C in the myotendinous junction and tendon but does not induce de novo synthesis in the skeletal muscle. J Cell Sci (2003) 1.71
Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc Natl Acad Sci U S A (2004) 1.69
Muscle injuries: optimising recovery. Best Pract Res Clin Rheumatol (2007) 1.62
Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice. Gastroenterology (2002) 1.57
The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice. Neurobiol Aging (2005) 1.53
UMD (Universal Mutation Database): 2005 update. Hum Mutat (2005) 1.52
Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors. Cancer Biol Ther (2003) 1.52
Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination. Cancer Biol Ther (2008) 1.48
Distal myopathy caused by homozygous missense mutations in the nebulin gene. Brain (2007) 1.46
Bedside diagnosis of rippling muscle disease in CAV3 p.A46T mutation carriers. Muscle Nerve (2010) 1.43
PDGF and PDGF receptors in glioma. Ups J Med Sci (2012) 1.43
Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma. Haematologica (2010) 1.42
VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy. Acta Neuropathol (2013) 1.34
Mitochondrial DNA sequence variation and mutation rate in patients with CADASIL. Neurogenetics (2006) 1.30
The UMD TP53 database and website: update and revisions. Hum Mutat (2006) 1.26
TP53 mutations in human cancer: database reassessment and prospects for the next decade. Hum Mutat (2014) 1.24
Cdk5 regulates the organization of Nestin and its association with p35. Mol Cell Biol (2003) 1.24
Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients. Brain (2009) 1.23
Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis. J Biol Chem (2010) 1.22
Fibrosis and stenosis of the long penetrating cerebral arteries: the cause of the white matter pathology in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Brain Pathol (2004) 1.22
Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases. J Neural Transm (Vienna) (2009) 1.22
Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors. Proc Natl Acad Sci U S A (2012) 1.17
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization. J Pathol (2012) 1.16
Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile. Neuro Oncol (2011) 1.16
Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma. PLoS One (2011) 1.16
Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation. PLoS One (2010) 1.16
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proc Natl Acad Sci U S A (2011) 1.08
Metabolic characterization of childhood brain tumors: comparison of 18F-fluorodeoxyglucose and 11C-methionine positron emission tomography. Cancer (2002) 1.07
Time-course and determinants of spasticity during the first six months following first-ever stroke. J Rehabil Med (2010) 1.07
Transcription factor PROX1: its role in development and cancer. Cancer Metastasis Rev (2012) 1.05
Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma. Neuro Oncol (2009) 1.05
CADASIL and CARASIL. Brain Pathol (2014) 1.05
Complementary effects of platelet-derived growth factor autocrine stimulation and p53 or Ink4a-Arf deletion in a mouse glioma model. Cancer Res (2003) 1.04
Low expression of p27 indicates a poor prognosis in patients with high-grade astrocytomas. Cancer (2003) 1.03
A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice. Neurobiol Aging (2008) 1.02
Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array. Neuro Oncol (2009) 1.02
Sox10 has a broad expression pattern in gliomas and enhances platelet-derived growth factor-B--induced gliomagenesis. Mol Cancer Res (2007) 1.01
GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background. Glia (2009) 1.00
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. Nucleic Acids Res (2012) 0.98
Mapping of tissue tropism determinants in coxsackievirus genomes. J Gen Virol (2002) 0.98
Rapid and sensitive p53 alteration analysis in biopsies from lung cancer patients using a functional assay and a universal oligonucleotide array: a prospective study. Clin Cancer Res (2004) 0.98
Insidious cognitive decline in CADASIL. Stroke (2004) 0.97
Tissue tropism of recombinant coxsackieviruses in an adult mouse model. J Gen Virol (2005) 0.97
Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells. Brain Pathol (2008) 0.97
Focus on the p53 gene and cancer: advances in TP53 mutation research. Hum Mutat (2003) 0.95
Differences in aberrant expression and splicing of sarcomeric proteins in the myotonic dystrophies DM1 and DM2. Acta Neuropathol (2010) 0.94
Expression of PROX1 Is a common feature of high-grade malignant astrocytic gliomas. J Neuropathol Exp Neurol (2010) 0.94
Arterioles of the lenticular nucleus in CADASIL. Stroke (2006) 0.94
Meta-analysis of cancer gene expression signatures reveals new cancer genes, SAGE tags and tumor associated regions of co-regulation. Nucleic Acids Res (2010) 0.94
Positron emission tomography examination of cerebral blood flow and glucose metabolism in young CADASIL patients. Stroke (2004) 0.93
Restoration of myofiber continuity after transection injury in the rat soleus. Neuromuscul Disord (2004) 0.93
Serum p53 antibodies in patients with lung cancer: correlation with clinicopathologic features and smoking. Lung Cancer (2003) 0.93
Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates. Cell Mol Life Sci (2012) 0.93
An endonuclease/ligase based mutation scanning method especially suited for analysis of neoplastic tissue. Oncogene (2002) 0.93
Neuropathologic findings of dementia with lewy bodies (DLB) in a population-based Vantaa 85+ study. J Alzheimers Dis (2009) 0.93
The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene. Gene (2002) 0.93
Quantitative fish determination of chromosome 3 arm imbalances in lung tumors by automated image cytometry. Med Sci Monit (2004) 0.93
Frozen tissue biobanks. Tissue handling, cryopreservation, extraction, and use for proteomic analysis. Acta Oncol (2006) 0.92
PI3K/PTEN/Akt pathway status affects the sensitivity of high-grade glioma cell cultures to the insulin-like growth factor-1 receptor inhibitor NVP-AEW541. Neuro Oncol (2010) 0.92
Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival. J Neurooncol (2006) 0.92
Prognostic but not predictive role of platelet-derived growth factor receptors in patients with recurrent glioblastoma. Int J Cancer (2011) 0.91
Novel mutations consolidate KCTD7 as a progressive myoclonus epilepsy gene. J Med Genet (2012) 0.91
Harmonized microarray/mutation scanning analysis of TP53 mutations in undissected colorectal tumors. Hum Mutat (2004) 0.91
The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation. J Cell Sci (2009) 0.90
Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients. J Cereb Blood Flow Metab (2007) 0.90
alpha-Synuclein pathology in the spinal cord autonomic nuclei associates with alpha-synuclein pathology in the brain: a population-based Vantaa 85+ study. Acta Neuropathol (2010) 0.89
Four new Finnish families with LGMD1D; refinement of the clinical phenotype and the linked 7q36 locus. Neuromuscul Disord (2011) 0.89
Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype. Genesis (2005) 0.89
A comparison between stem cells from the adult human brain and from brain tumors. Neurosurgery (2008) 0.89
Perfusion and diffusion MRI combined with ¹¹C-methionine PET in the preoperative evaluation of suspected adult low-grade gliomas. J Neurooncol (2013) 0.88
Neurofibrillary tau pathology modulated by genetic variation of alpha-synuclein. Ann Neurol (2008) 0.88
Detection of the founder effect in Finnish CADASIL families. Eur J Hum Genet (2004) 0.88
Adult course in dynamin 2 dominant centronuclear myopathy with neonatal onset. Neuromuscul Disord (2009) 0.88
A study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survival. Int J Cancer (2013) 0.88
ThinPrep-processed fine-needle samples of breast are effective material for RNA- and DNA-based molecular diagnosis: application to p53 mutation analysis. Cancer (2003) 0.88
Expression of alpha7beta1 integrin splicing variants during skeletal muscle regeneration. Am J Pathol (2002) 0.87
Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12. PLoS One (2011) 0.86
Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors. J Oncol (2010) 0.86