Published in Curr Opin Chem Biol on October 01, 2007
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26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2009) 1.71
Genome-wide identification, organization and phylogenetic analysis of Dicer-like, Argonaute and RNA-dependent RNA Polymerase gene families and their expression analysis during reproductive development and stress in rice. BMC Genomics (2008) 1.46
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Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. EMBO J (2012) 1.21
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Small RNAs with 5'-polyphosphate termini associate with a Piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica. PLoS Pathog (2008) 1.17
Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing. RNA Biol (2012) 1.10
The PIWI protein acts as a predictive marker for human gastric cancer. Int J Clin Exp Pathol (2012) 1.09
MIWI-independent small RNAs (MSY-RNAs) bind to the RNA-binding protein, MSY2, in male germ cells. Proc Natl Acad Sci U S A (2009) 1.00
Cell stress is related to re-localization of Argonaute 2 and to decreased RNA interference in human cells. Nucleic Acids Res (2010) 0.96
Historical survey on chromatoid body research. Acta Histochem Cytochem (2008) 0.94
Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product. Dev Biol (2010) 0.92
Cigarette smoke exposure-associated alterations to non-coding RNA. Front Genet (2012) 0.91
Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration. Dev Growth Differ (2012) 0.91
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Modeling the asymmetric evolution of a mouse and rat-specific microRNA gene cluster intron 10 of the Sfmbt2 gene. BMC Genomics (2011) 0.79
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Host-virus interaction: the antiviral defense function of small interfering RNAs can be enhanced by host microRNA-7 in vitro. Sci Rep (2015) 0.75
Paramecium tetraurelia chromatin assembly factor-1-like protein PtCAF-1 is involved in RNA-mediated control of DNA elimination. Nucleic Acids Res (2014) 0.75
Global identification and expression analysis of stress-responsive genes of the Argonaute family in apple. Mol Genet Genomics (2016) 0.75
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
Crystal structure of Argonaute and its implications for RISC slicer activity. Science (2004) 12.48
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol (2005) 12.12
A distinct small RNA pathway silences selfish genetic elements in the germline. Science (2006) 11.63
The small RNA profile during Drosophila melanogaster development. Dev Cell (2003) 11.46
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
Ribo-gnome: the big world of small RNAs. Science (2005) 10.10
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature (2006) 9.88
On the role of RNA amplification in dsRNA-triggered gene silencing. Cell (2001) 9.78
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev (2006) 8.78
RNAi-mediated targeting of heterochromatin by the RITS complex. Science (2004) 8.73
Characterization of the piRNA complex from rat testes. Science (2006) 7.86
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat Cell Biol (2005) 7.69
Developmentally regulated piRNA clusters implicate MILI in transposon control. Science (2007) 7.68
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature (2004) 7.63
A role for the P-body component GW182 in microRNA function. Nat Cell Biol (2005) 7.54
Methylation as a crucial step in plant microRNA biogenesis. Science (2005) 7.16
EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr Biol (2000) 7.16
Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science (2006) 7.15
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell (2006) 7.14
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature (2005) 7.12
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr Biol (2001) 7.06
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol (2003) 6.90
A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev (1998) 6.74
Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol (2005) 6.64
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev (2006) 6.60
Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science (2004) 6.35
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature (2005) 6.23
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science (2006) 5.49
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol (2007) 5.35
Strategies for silencing human disease using RNA interference. Nat Rev Genet (2007) 5.19
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA (2005) 5.15
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain. Nature (2003) 4.92
RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol Cell (2002) 4.90
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends. Genes Dev (2007) 4.68
Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat Struct Mol Biol (2004) 4.38
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. Mol Cell (2005) 4.11
Slicer and the argonautes. Nat Chem Biol (2007) 3.99
zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev Cell (2007) 3.29
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini. Nat Struct Mol Biol (2007) 2.89
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated. Nat Struct Mol Biol (2007) 2.71
Argonaute: A scaffold for the function of short regulatory RNAs. Trends Biochem Sci (2006) 2.28
Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. EMBO J (2006) 2.23
MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay. Cold Spring Harb Symp Quant Biol (2006) 2.12
Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05
Structure and function of argonaute proteins. Structure (2005) 1.84
The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs. RNA (2007) 1.77
Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site. Proteins (1993) 1.46
Argonaute and RNA--getting into the groove. Curr Opin Struct Biol (2006) 1.35
Evidence for "unseen" transposase--DNA contacts. J Mol Biol (2002) 0.93
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Crystal structure of Argonaute and its implications for RISC slicer activity. Science (2004) 12.48
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell (2006) 7.14
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol (2003) 6.90
Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol (2005) 6.64
Mechanism of DNA translocation in a replicative hexameric helicase. Nature (2006) 4.91
Slicer and the argonautes. Nat Chem Biol (2007) 3.99
Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell (2005) 3.79
The structure of human argonaute-2 in complex with miR-20a. Cell (2012) 2.83
Argonaute slicing is required for heterochromatic silencing and spreading. Science (2006) 2.48
On helicases and other motor proteins. Curr Opin Struct Biol (2008) 2.43
A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails. Genes Dev (2012) 2.13
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature (2012) 1.97
High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin. Mol Cell (2009) 1.65
Strategies for protein coexpression in Escherichia coli. Nat Methods (2006) 1.58
Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex. EMBO J (2002) 1.45
Argonaute and RNA--getting into the groove. Curr Opin Struct Biol (2006) 1.35
Eukaryotic Argonautes come into focus. Trends Biochem Sci (2013) 1.19
The making of a slicer: activation of human Argonaute-1. Cell Rep (2013) 1.15
NADP regulates the yeast GAL induction system. Science (2008) 1.15
The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nat Struct Mol Biol (2011) 1.02
Dynamic look at DNA unwinding by a replicative helicase. Proc Natl Acad Sci U S A (2014) 0.96
Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell Rep (2013) 0.92
Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster. Biochemistry (2002) 0.90
The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J Biol Chem (2003) 0.88
Argonaute MID domain takes centre stage. EMBO Rep (2010) 0.84
The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes Dev (2012) 0.81
Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants. J Biol Chem (2001) 0.79
Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure. Biochem J (2007) 0.79
CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Proc Natl Acad Sci U S A (2014) 0.78
siRNAs at RISC. Structure (2004) 0.77
Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution. Acta Crystallogr D Biol Crystallogr (2002) 0.75