Essential role for Dicer during skeletal muscle development.

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The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell (2013) 3.27

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10

MicroRNA control of muscle development and disease. Curr Opin Cell Biol (2009) 3.04

MicroRNA-206: the skeletal muscle-specific myomiR. Biochim Biophys Acta (2008) 2.64

Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol (2008) 2.51

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50

Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44

MicroRNAs as novel regulators of angiogenesis. Circ Res (2009) 2.33

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miR-206 and -486 induce myoblast differentiation by downregulating Pax7. Mol Cell Biol (2010) 2.10

Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol (2008) 1.91

Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation. Nat Cell Biol (2012) 1.89

MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. Mol Biol Cell (2010) 1.89

Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury. J Am Soc Nephrol (2010) 1.82

MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesis. Genes Dev (2010) 1.79

microRNAs and muscle disorders. J Cell Sci (2009) 1.73

Dicer1 is essential for female fertility and normal development of the female reproductive system. Endocrinology (2008) 1.71

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat Immunol (2011) 1.67

Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol (2009) 1.62

IGF-II is regulated by microRNA-125b in skeletal myogenesis. J Cell Biol (2011) 1.62

The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60

MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3. J Cell Biol (2010) 1.52

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Dev Biol (2010) 1.52

In search of adrenocortical stem and progenitor cells. Endocr Rev (2009) 1.51

miR-26a is required for skeletal muscle differentiation and regeneration in mice. Genes Dev (2012) 1.46

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microRNAs and genetic diseases. Pathogenetics (2009) 1.32

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The pro-apoptotic protein Bim is a microRNA target in kidney progenitors. J Am Soc Nephrol (2011) 1.27

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MicroRNA-148a promotes myogenic differentiation by targeting the ROCK1 gene. J Biol Chem (2012) 1.20

A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAs. BMC Genomics (2011) 1.20

MicroRNA-deficient Schwann cells display congenital hypomyelination. J Neurosci (2010) 1.19

Dicer is required for survival of differentiating neural crest cells. Dev Biol (2010) 1.19

Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem (2012) 1.15

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis. Cell Death Differ (2011) 1.11

Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects. PLoS One (2011) 1.10

MicroRNA expression in alpha and beta cells of human pancreatic islets. PLoS One (2013) 1.08

A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene (2013) 1.04

Estrogen induces distinct patterns of microRNA expression within the mouse uterus. Reprod Sci (2010) 1.03

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Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. PLoS One (2009) 1.01

Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Mol Cell Biol (2010) 1.00

Reduction of Dicer impairs Schwann cell differentiation and myelination. J Neurosci Res (2010) 0.99

Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn (2009) 0.98

MicroRNAs in metabolism. Acta Physiol (Oxf) (2016) 0.97

Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro. Exp Neurol (2011) 0.96

Role of heme oxygenase-1 in postnatal differentiation of stem cells: a possible cross-talk with microRNAs. Antioxid Redox Signal (2014) 0.94

The magic and mystery of miR-21. J Clin Invest (2010) 0.94

Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice. PLoS One (2014) 0.93

MicroRNA signature of the human developing pancreas. BMC Genomics (2010) 0.93

Steroidal regulation of uterine miRNAs is associated with modulation of the miRNA biogenesis components Exportin-5 and Dicer1. Endocrine (2010) 0.93

MicroRNAs regulate and provide robustness to the myogenic transcriptional network. Curr Opin Pharmacol (2012) 0.93

Integrative analysis of porcine microRNAome during skeletal muscle development. PLoS One (2013) 0.92

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts. Genes Dev (2013) 0.91

Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells (2010) 0.90

MicroRNA-34a modulates cytoskeletal dynamics through regulating RhoA/Rac1 cross-talk in chondroblasts. J Biol Chem (2012) 0.90

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet (2012) 0.89

The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol (2011) 0.89

Dicer activity in neural crest cells is essential for craniofacial organogenesis and pharyngeal arch artery morphogenesis. Mech Dev (2011) 0.89

Epigenetic regulation of muscle phenotype and adaptation: a potential role in COPD muscle dysfunction. J Appl Physiol (1985) (2013) 0.88

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Identification of differences in microRNA transcriptomes between porcine oxidative and glycolytic skeletal muscles. BMC Mol Biol (2013) 0.88

MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality. Mol Cancer (2011) 0.88

Epigenetic regulation of muscle development. J Muscle Res Cell Motil (2017) 0.87

The role of muscle microRNAs in repairing the neuromuscular junction. PLoS One (2014) 0.86

MicroRNA-206: a promising theranostic marker. Theranostics (2014) 0.85

Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol (2013) 0.85

Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations. PLoS One (2012) 0.85

MicroRNA-146b promotes myogenic differentiation and modulates multiple gene targets in muscle cells. PLoS One (2014) 0.84

The role of microRNAs in skeletal muscle health and disease. Front Biosci (Landmark Ed) (2015) 0.84

MicroRNAs in cardiac development and remodeling. Pediatr Cardiol (2010) 0.84

miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. Genes Dev (2015) 0.83

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Regulation of lipid metabolism by Dicer revealed through SILAC mice. J Proteome Res (2012) 0.82

Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes (2013) 0.82

Comparison of skeletal muscle miRNA and mRNA profiles among three pig breeds. Mol Genet Genomics (2015) 0.82

Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers. Mol Cell Biol (2015) 0.81

miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One (2015) 0.81

RNA surveillance-an emerging role for RNA regulatory networks in aging. Ageing Res Rev (2010) 0.81

Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. Biomed Res Int (2015) 0.80

The role of Dicer1 in the male reproductive tract. Asian J Androl (2015) 0.80

Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells. Physiol Genomics (2014) 0.80

The tiny world of microRNAs in the cross hairs of the mammalian eye. Hum Genomics (2009) 0.80

Novel DICER1 mutation as cause of multinodular goiter in children. Head Neck (2013) 0.80

MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nat Commun (2015) 0.79

Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J (2013) 0.79

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Identification and profiling of microRNAs in the embryonic breast muscle of pekin duck. PLoS One (2014) 0.78

MicroRNA-30a regulates zebrafish myogenesis through targeting the transcription factor Six1. J Cell Sci (2014) 0.77

Measuring microRNA reporter activity in skeletal muscle using hydrodynamic limb vein injection of plasmid DNA combined with in vivo imaging. Skelet Muscle (2013) 0.76

miRNA transcriptome of hypertrophic skeletal muscle with overexpressed myostatin propeptide. Biomed Res Int (2014) 0.76

Mechanical stretch regulates microRNA expression profile via NF-κB activation in C2C12 myoblasts. Mol Med Rep (2016) 0.75

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Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15

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MicroRNA-cancer connection: the beginning of a new tale. Cancer Res (2006) 7.38

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Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87

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The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol (2006) 3.64

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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56

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Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med (2008) 4.68

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Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98

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A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell (2013) 3.53

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A (2003) 3.48

Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron (2010) 3.37

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33

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Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27

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Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. Mol Cell (2004) 3.15

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MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 2.80

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Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy. J Clin Invest (2007) 2.68

The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61

Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev (2004) 2.55

MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex. Mol Cell Biol (2005) 2.55

Identification of progenitor cells that contribute to heterotopic skeletogenesis. J Bone Joint Surg Am (2009) 2.53

RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy. Hum Mol Genet (2009) 2.51

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Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet (2013) 2.46

RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet (2009) 2.45

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Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A (2008) 2.32

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IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science (2012) 2.25

An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. Hum Mol Genet (2007) 2.25

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A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation. Genes Dev (2004) 2.16

Regulation of thalamocortical patterning and synaptic maturation by NeuroD2. Neuron (2006) 2.15

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Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol (2007) 2.03

Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. Nat Genet (2005) 1.99

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Small molecule regulators of protein arginine methyltransferases. J Biol Chem (2004) 1.99

TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98

Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods (2009) 1.98

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Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. J Biol Chem (2010) 1.93

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TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology (2009) 1.86

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Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy. J Gen Physiol (2006) 1.83

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J (2010) 1.82

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Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron (2012) 1.78

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